Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with ...Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with suspected diagnosis of congenital uterine anomalies by previous HSG or 2D US examinations, were evaluated by transvaginal 3-D US. The 3-D US diagnoses were compared to the initial HSG diagnosis, and to hysteroscopic evaluation when performed. Results: 3-D scan confirmed the initial HSG diagnosis in 27 out of 51 (52.9%) women. The concordancy rates between the initial diagnosis by HSG and 3-D US results were 30.4% for bicornuate uterus;75% for arcuate uterus;83% for septate uterus;and 80% for unicornuate uterus. Of the 13 cases with normal HSG and suspicious 2-D US, 30.8% were found to be normal by 3D sonography. In cases where hysteroscopy was done, the results were 100% in concordance with the 3-D US evaluations. Conclusions: 3-D US is an accurate test for the assessment of uterine congenital anomalies. Its ability to concomitantly visualized, the external uterine contour with the uterine cavity on the same coronal plan, makes this noninvasive, easy to perform test the procedure of choice for the diagnosis of uterine anomalies.展开更多
Lie group analysis method is applied to the extended(3+1)-dimensional Kadomtsev–Petviashvili–Boussinesq equation and the corresponding similarity reduction equations are obtained with various infinitesimal generator...Lie group analysis method is applied to the extended(3+1)-dimensional Kadomtsev–Petviashvili–Boussinesq equation and the corresponding similarity reduction equations are obtained with various infinitesimal generators.By selecting suitable arbitrary functions in the similarity reduction solutions,we obtain abundant invariant solutions,including the trigonometric solution,the kink-lump interaction solution,the interaction solution between lump wave and triangular periodic wave,the two-kink solution,the lump solution,the interaction between a lump and two-kink and the periodic lump solution in different planes.These exact solutions are also given graphically to show the detailed structures of this high dimensional integrable system.展开更多
Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing...Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.展开更多
Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast ...Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast nodules of BI-RADS 3 or above were selected as the research subjects.After pathological diagnosis,24 cases were malignant breast nodules of BI-RADS 3 or above,while 139 cases were benign breast nodules of BI-RADS 3 or above.The diagnosis rate of malignant and benign breast nodules of BI-RADS 3 or above,including 95%CI,was observed and analyzed.Results:The malignant and benign detection rates of conventional ultrasound were 88.63%and 75.00%,respectively,and the malignant and benign detection rates of ultrasound imaging were 93.18%and 87.50%,respectively,with 95%CIs greater than 0.7.Conclusion:Ultrasound imaging can help improve the diagnostic accuracy of benign and malignant breast nodules of BI-RADS 3 and above and reduce the misdiagnosis rate.展开更多
Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with a...Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically.展开更多
Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions be...Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions.展开更多
Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of t...Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.展开更多
The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its ma...The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data展开更多
Using elementary integral method, a complete classification of all possible exact traveling wave solutions to （3＋1）-dimensional Nizhnok-Novikov-Veselov equation is given. Some solutions are new.
Using the modified find some new exact solutions to Lie point symmetry groups and also get conservation laws, of the CK＇s direct method, we build the relationship between new solutions and old ones and the （3＋1）-d...Using the modified find some new exact solutions to Lie point symmetry groups and also get conservation laws, of the CK＇s direct method, we build the relationship between new solutions and old ones and the （3＋1）-dimensional potentiaial-YTSF equation. Baaed on the invariant group theory, Lie symmetries of the （3＋1）-dimensional potential-YTSF equation are obtained. We equation with the given Lie symmetry.展开更多
This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome（OSAHS） by using dynamic 3-Dimensional（3-D） CT imaging.A tota...This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome（OSAHS） by using dynamic 3-Dimensional（3-D） CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller＇s maneuver.The soft palate length（SPL）,the minimal cross-sectional area of the retropalatal region（mXSA-RP）,and the vertical distance from the hard palate to the upper posterior part of the hyoid（hhL） were compared between the two breathing states.These parameters,together with hard palate length（HPL）,were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index（AHI） and the lowest saturation of blood oxygen（LSaO2）] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller＇s maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters（except the position of the hyoid bone） between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index（BMI）≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller＇s maneuver than those in group with BMI26（P0.05 for all）.It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26.展开更多
Based on the Pfaffian derivative formulae,a Grammian determinant solution for a(3+1)-dimensionalsoliton equation is obtained.Moreover,the Pfaffianization procedure is applied for the equation to generate a newcoupled ...Based on the Pfaffian derivative formulae,a Grammian determinant solution for a(3+1)-dimensionalsoliton equation is obtained.Moreover,the Pfaffianization procedure is applied for the equation to generate a newcoupled system.At last,a Gram-type Pfaffian solution to the new coupled system is given.展开更多
The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmissio...The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers.展开更多
The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma（HCC） treated by sequential therapy of transcatheter arterial chemoembolization（TACE）,three-dimensional c...The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma（HCC） treated by sequential therapy of transcatheter arterial chemoembolization（TACE）,three-dimensional conformal radiotherapy（3-DCRT） and high-intensity focused ultrasound（HIFU）.From October,2005 to September,2010,120 patients with unresectable HCC received the sequential treatments of several courses of TACE followed in 2-4 weeks by 3-DCRT and then a single session of HIFU with a curative intent.The median tumor irradiation dose was 40 Gy.Tumor response,toxicity and overall survival rate were analyzed.Clinicopathologic factors affecting the primary technique effectiveness and overall survival rates were investigated by univariate analysis or multivariate analysis.All 120 HCC patients were followed up by the last follow-up time.Among these patients,hepatic toxicities due to treatment were notable in 9 cases.Gastrointestinal bleeding after the overall treatment occurred in 2 cases,leukopenia of grade III was detected in 1 case,radiation-induced liver disease（RILD） was observed in 2 patients,and first-and second-degree skin burn around the HIFU treatment zone were observed in 2 patients and 1 patient,respectively.Among 120 patients,23,83 and 14 cases achieved partial response,stable disease and progressive disease,respectively.The overall survival rates at 1 year,3 years and 5 years were 70%,35% and 15%,respectively,with a median survival time of 26 months.Both Child-Pugh liver function grading and radiation dose were determined to be independent predictors for overall survival revealed by the multivariate analysis.It is concluded that the sequential therapy of TACE,3-DCRT and HIFU is a promising therapeutic regimen for unresectable HCC.展开更多
We obtain exact spatiotemporal similaritons to a （3＋ l）-dimensional inhomogeneous nonlinear Schrodinger equation, which describes the propagation of optical pulses in a cubic-quintic nonlinearity medium with distri...We obtain exact spatiotemporal similaritons to a （3＋ l）-dimensional inhomogeneous nonlinear Schrodinger equation, which describes the propagation of optical pulses in a cubic-quintic nonlinearity medium with distributed dispersion and gain. A one-to-one correspondence between such self-similar waves and solutions of the elliptic equation is found when a certain compatibility condition is satisfied. Based on exact solutions, we discuss evolutional behaviors of self-similar cnoidal waves and chirped similaritons in two kind of typicai soliton control systems. Moreover, the comparison between chirped similaritons and chirp-free solitons is given.展开更多
Using the extended homogeneous balance method, we find some special types of single solitary wave solution and new types of the multisoliton solutions of the (3+1)-dimensional Jimbo-Miwa equation.
文摘Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with suspected diagnosis of congenital uterine anomalies by previous HSG or 2D US examinations, were evaluated by transvaginal 3-D US. The 3-D US diagnoses were compared to the initial HSG diagnosis, and to hysteroscopic evaluation when performed. Results: 3-D scan confirmed the initial HSG diagnosis in 27 out of 51 (52.9%) women. The concordancy rates between the initial diagnosis by HSG and 3-D US results were 30.4% for bicornuate uterus;75% for arcuate uterus;83% for septate uterus;and 80% for unicornuate uterus. Of the 13 cases with normal HSG and suspicious 2-D US, 30.8% were found to be normal by 3D sonography. In cases where hysteroscopy was done, the results were 100% in concordance with the 3-D US evaluations. Conclusions: 3-D US is an accurate test for the assessment of uterine congenital anomalies. Its ability to concomitantly visualized, the external uterine contour with the uterine cavity on the same coronal plan, makes this noninvasive, easy to perform test the procedure of choice for the diagnosis of uterine anomalies.
文摘Lie group analysis method is applied to the extended(3+1)-dimensional Kadomtsev–Petviashvili–Boussinesq equation and the corresponding similarity reduction equations are obtained with various infinitesimal generators.By selecting suitable arbitrary functions in the similarity reduction solutions,we obtain abundant invariant solutions,including the trigonometric solution,the kink-lump interaction solution,the interaction solution between lump wave and triangular periodic wave,the two-kink solution,the lump solution,the interaction between a lump and two-kink and the periodic lump solution in different planes.These exact solutions are also given graphically to show the detailed structures of this high dimensional integrable system.
基金Macao Polytechnic University Grant(RP/FCSD-01/2022RP/FCA-05/2022)Science and Technology Development Fund of Macao(0105/2022/A).
文摘Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.
文摘Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast nodules of BI-RADS 3 or above were selected as the research subjects.After pathological diagnosis,24 cases were malignant breast nodules of BI-RADS 3 or above,while 139 cases were benign breast nodules of BI-RADS 3 or above.The diagnosis rate of malignant and benign breast nodules of BI-RADS 3 or above,including 95%CI,was observed and analyzed.Results:The malignant and benign detection rates of conventional ultrasound were 88.63%and 75.00%,respectively,and the malignant and benign detection rates of ultrasound imaging were 93.18%and 87.50%,respectively,with 95%CIs greater than 0.7.Conclusion:Ultrasound imaging can help improve the diagnostic accuracy of benign and malignant breast nodules of BI-RADS 3 and above and reduce the misdiagnosis rate.
文摘Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically.
文摘Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11975156 and 12175148)。
文摘Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.
文摘The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data
基金The project supported by Scientific Research Fund of Heilongjiang Province of China under Grant No. 11511008The author would like to thank referees for their valuable suggestions.
文摘Using elementary integral method, a complete classification of all possible exact traveling wave solutions to （3＋1）-dimensional Nizhnok-Novikov-Veselov equation is given. Some solutions are new.
基金The project supported by the Natural Science Foundation of Shandong Province of China under Grant No. 2004zx16 tCorresponding author, E-maih zzlh100@163.com
文摘Using the modified find some new exact solutions to Lie point symmetry groups and also get conservation laws, of the CK＇s direct method, we build the relationship between new solutions and old ones and the （3＋1）-dimensional potentiaial-YTSF equation. Baaed on the invariant group theory, Lie symmetries of the （3＋1）-dimensional potential-YTSF equation are obtained. We equation with the given Lie symmetry.
文摘This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome（OSAHS） by using dynamic 3-Dimensional（3-D） CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller＇s maneuver.The soft palate length（SPL）,the minimal cross-sectional area of the retropalatal region（mXSA-RP）,and the vertical distance from the hard palate to the upper posterior part of the hyoid（hhL） were compared between the two breathing states.These parameters,together with hard palate length（HPL）,were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index（AHI） and the lowest saturation of blood oxygen（LSaO2）] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller＇s maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters（except the position of the hyoid bone） between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index（BMI）≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller＇s maneuver than those in group with BMI26（P0.05 for all）.It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26.
文摘Based on the Pfaffian derivative formulae,a Grammian determinant solution for a(3+1)-dimensionalsoliton equation is obtained.Moreover,the Pfaffianization procedure is applied for the equation to generate a newcoupled system.At last,a Gram-type Pfaffian solution to the new coupled system is given.
基金This project is supported by National 863 Plan of China (No. 512-9804- 02) and 863 Opening Robot Laboratory Foundation of Shenyang Institute Automation of Chinese Academy of Sciences.
文摘The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers.
文摘The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma（HCC） treated by sequential therapy of transcatheter arterial chemoembolization（TACE）,three-dimensional conformal radiotherapy（3-DCRT） and high-intensity focused ultrasound（HIFU）.From October,2005 to September,2010,120 patients with unresectable HCC received the sequential treatments of several courses of TACE followed in 2-4 weeks by 3-DCRT and then a single session of HIFU with a curative intent.The median tumor irradiation dose was 40 Gy.Tumor response,toxicity and overall survival rate were analyzed.Clinicopathologic factors affecting the primary technique effectiveness and overall survival rates were investigated by univariate analysis or multivariate analysis.All 120 HCC patients were followed up by the last follow-up time.Among these patients,hepatic toxicities due to treatment were notable in 9 cases.Gastrointestinal bleeding after the overall treatment occurred in 2 cases,leukopenia of grade III was detected in 1 case,radiation-induced liver disease（RILD） was observed in 2 patients,and first-and second-degree skin burn around the HIFU treatment zone were observed in 2 patients and 1 patient,respectively.Among 120 patients,23,83 and 14 cases achieved partial response,stable disease and progressive disease,respectively.The overall survival rates at 1 year,3 years and 5 years were 70%,35% and 15%,respectively,with a median survival time of 26 months.Both Child-Pugh liver function grading and radiation dose were determined to be independent predictors for overall survival revealed by the multivariate analysis.It is concluded that the sequential therapy of TACE,3-DCRT and HIFU is a promising therapeutic regimen for unresectable HCC.
基金Supported by the National Natural Science Foundation of China under Grant No.10974177by the Ministry of Science and Technology of China under Grant No.2010DFA04690
文摘We obtain exact spatiotemporal similaritons to a （3＋ l）-dimensional inhomogeneous nonlinear Schrodinger equation, which describes the propagation of optical pulses in a cubic-quintic nonlinearity medium with distributed dispersion and gain. A one-to-one correspondence between such self-similar waves and solutions of the elliptic equation is found when a certain compatibility condition is satisfied. Based on exact solutions, we discuss evolutional behaviors of self-similar cnoidal waves and chirped similaritons in two kind of typicai soliton control systems. Moreover, the comparison between chirped similaritons and chirp-free solitons is given.
文摘Using the extended homogeneous balance method, we find some special types of single solitary wave solution and new types of the multisoliton solutions of the (3+1)-dimensional Jimbo-Miwa equation.
