Objective: To study the effect of RFTVR and CO2 laser on the improvement of symptoms, QOL and vas of patients with early laryngeal cancer. Methods: In this study, 120 patients with laryngeal cancer diagnosed and treat...Objective: To study the effect of RFTVR and CO2 laser on the improvement of symptoms, QOL and vas of patients with early laryngeal cancer. Methods: In this study, 120 patients with laryngeal cancer diagnosed and treated from January 2015 to December 2016 were taken as research objects. All patients were randomly divided into observation group and control group, 60 patients in each group. Patients in observation group were treated with RFTVR, and patients in control group were treated with new-type fiber-optic CO2 laser. The patients in the two groups were treated with cisplatin injection. The differences of perioperative indexes, swallowing function, pronunciation function, survival period, QOL score and VAS score between the two groups were compared. Results: There was no significant difference in the amount of intraoperative bleeding, operation time and hospitalization time between the two groups (P > 0.05);the correct swallowing of the observation group was significantly higher than that of the control group. After treatment, jitter, shimmer and HNR of the two groups were significantly improved, and jitter and shimmer of the observation group were significantly lower than that of the control group, and HNR was significantly higher than that of the control group (P < 0.05) The QOL score and VAS score of the two groups were significantly improved, and the QOL score of the observation group was significantly higher than that of the control group and the VAS score was significantly lower than that of the control group (P < 0.05);the total survival period and tumor free survival period of the observation group were significantly higher than that of the control group. Conclusion: Compared with CO2 laser treatment, the swallowing function and voice function of patients treated by low temperature plasma radiofrequency ablation were significantly improved, and the life quality of patients was significantly improved by prolonging the survival period of patients..展开更多
Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Er...Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed展开更多
Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injectio...Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.展开更多
目的比较CO2激光鼓膜造孔术及鼓膜置管术治疗儿童分泌性中耳炎(Otitis media with effusion,OME的临床疗效,探讨CO2激光鼓膜造孔术能否替代鼓膜置管术。方法79例(139耳)OME患儿随机分为两组:激光组:40例(73耳)采用CO2激光鼓膜造孔术;置...目的比较CO2激光鼓膜造孔术及鼓膜置管术治疗儿童分泌性中耳炎(Otitis media with effusion,OME的临床疗效,探讨CO2激光鼓膜造孔术能否替代鼓膜置管术。方法79例(139耳)OME患儿随机分为两组:激光组:40例(73耳)采用CO2激光鼓膜造孔术;置管组:39例(66耳)采用鼓膜置管术。比较两种手术方法的有效率、复发率、并发症发生率以及浆液型、粘液型鼓室积液的治疗效果。结果术后6月激光组治疗有效率63.01%,置管组治疗有效率84.85%,两组差异有统计学意义(χ^2=8.460,P=0.004);激光组鼓膜穿孔平均愈合时间为19.49±5.774天;激光组的复发率为31.5%,置管组的复发率为9.09%,两组差异有统计学意义(χ^2=10.549,P=0.001);激光组并发症发生率为2.74%,置管组并发症发生率为13.64%,两组差异有统计学意义(χ^2=5.648,P=0.017);浆液型积液耳激光组与置管组治疗有效率比较差异无统计学意义(χ^2=1.801,P=0.180),粘液型积液耳激光组与置管组治疗有效率比较差异有统计学意义(χ^2=5.064,P=0.024),置管组有效率优于激光组。结论CO2激光鼓膜造孔术是治疗儿童OME的一种安全、有效的术式,但并未能因此代替鼓膜置管术,需根据患儿是否伴发合并症情况及鼓室积液类型选择合适的手术方法,对于鼓室积液粘稠、同时合并有腺样体肥大、慢性鼻-鼻窦炎或过敏性鼻炎等合并症患者,鼓膜置管术仍为最有效的手术方式。展开更多
报道了一种采用双路高速伺服电机驱动光栅选线的方式,实现9~11μm CO2激光快速调谐输出。双光路谱线切换时间小于100μs,单光路谱线切换时间小于50 ms。激光器输出谱线达70条,其中9P(20)、9P(28)单脉冲输出能量大于100 m J,9R(30)、9P(...报道了一种采用双路高速伺服电机驱动光栅选线的方式,实现9~11μm CO2激光快速调谐输出。双光路谱线切换时间小于100μs,单光路谱线切换时间小于50 ms。激光器输出谱线达70条,其中9P(20)、9P(28)单脉冲输出能量大于100 m J,9R(30)、9P(40)单脉冲能量大于90 m J,激光脉冲宽度小于100 ns,重复频率为20 Hz。展开更多
基金State key laboratory of medical immunology open project (NKMI2019K07)
文摘Objective: To study the effect of RFTVR and CO2 laser on the improvement of symptoms, QOL and vas of patients with early laryngeal cancer. Methods: In this study, 120 patients with laryngeal cancer diagnosed and treated from January 2015 to December 2016 were taken as research objects. All patients were randomly divided into observation group and control group, 60 patients in each group. Patients in observation group were treated with RFTVR, and patients in control group were treated with new-type fiber-optic CO2 laser. The patients in the two groups were treated with cisplatin injection. The differences of perioperative indexes, swallowing function, pronunciation function, survival period, QOL score and VAS score between the two groups were compared. Results: There was no significant difference in the amount of intraoperative bleeding, operation time and hospitalization time between the two groups (P > 0.05);the correct swallowing of the observation group was significantly higher than that of the control group. After treatment, jitter, shimmer and HNR of the two groups were significantly improved, and jitter and shimmer of the observation group were significantly lower than that of the control group, and HNR was significantly higher than that of the control group (P < 0.05) The QOL score and VAS score of the two groups were significantly improved, and the QOL score of the observation group was significantly higher than that of the control group and the VAS score was significantly lower than that of the control group (P < 0.05);the total survival period and tumor free survival period of the observation group were significantly higher than that of the control group. Conclusion: Compared with CO2 laser treatment, the swallowing function and voice function of patients treated by low temperature plasma radiofrequency ablation were significantly improved, and the life quality of patients was significantly improved by prolonging the survival period of patients..
文摘Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed
基金This work was supported by the Distinguished Professors Funding from Shenzhen University, the National Science Foundation of China （Grant 11174064）, and the Science ＆ Technology Innovation Commission of Shenzhen （Grant KQCX20120815161444632）.
文摘Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.
文摘目的比较CO2激光鼓膜造孔术及鼓膜置管术治疗儿童分泌性中耳炎(Otitis media with effusion,OME的临床疗效,探讨CO2激光鼓膜造孔术能否替代鼓膜置管术。方法79例(139耳)OME患儿随机分为两组:激光组:40例(73耳)采用CO2激光鼓膜造孔术;置管组:39例(66耳)采用鼓膜置管术。比较两种手术方法的有效率、复发率、并发症发生率以及浆液型、粘液型鼓室积液的治疗效果。结果术后6月激光组治疗有效率63.01%,置管组治疗有效率84.85%,两组差异有统计学意义(χ^2=8.460,P=0.004);激光组鼓膜穿孔平均愈合时间为19.49±5.774天;激光组的复发率为31.5%,置管组的复发率为9.09%,两组差异有统计学意义(χ^2=10.549,P=0.001);激光组并发症发生率为2.74%,置管组并发症发生率为13.64%,两组差异有统计学意义(χ^2=5.648,P=0.017);浆液型积液耳激光组与置管组治疗有效率比较差异无统计学意义(χ^2=1.801,P=0.180),粘液型积液耳激光组与置管组治疗有效率比较差异有统计学意义(χ^2=5.064,P=0.024),置管组有效率优于激光组。结论CO2激光鼓膜造孔术是治疗儿童OME的一种安全、有效的术式,但并未能因此代替鼓膜置管术,需根据患儿是否伴发合并症情况及鼓室积液类型选择合适的手术方法,对于鼓室积液粘稠、同时合并有腺样体肥大、慢性鼻-鼻窦炎或过敏性鼻炎等合并症患者,鼓膜置管术仍为最有效的手术方式。
文摘报道了一种采用双路高速伺服电机驱动光栅选线的方式,实现9~11μm CO2激光快速调谐输出。双光路谱线切换时间小于100μs,单光路谱线切换时间小于50 ms。激光器输出谱线达70条,其中9P(20)、9P(28)单脉冲输出能量大于100 m J,9R(30)、9P(40)单脉冲能量大于90 m J,激光脉冲宽度小于100 ns,重复频率为20 Hz。
