Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mo...Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mongolian medicine combined with external application for treatment,combination of Mongolian medicine acupuncture therapy and oral administration of Mongolian medicine for treatment,integrated treatment of Mongolian and Western medicine,and combination therapy of Mongolian and traditional Chinese medicine,providing new ideas and choices for clinical research.展开更多
Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie ...Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.展开更多
In this work,the current status,technical capabilities,and development trends of the Chinese intelligent furniture industry were in focus.Based on combining a literature review with field investigations and analysis o...In this work,the current status,technical capabilities,and development trends of the Chinese intelligent furniture industry were in focus.Based on combining a literature review with field investigations and analysis of major scientific research projects in Zhejiang Province,China,an in-depth overview and discussion about previous experience,features,technologies,products and control methods in the intelligent furniture industry in China were conducted.The key technologies in current Chinese intelligent furniture industry include embedded systems,sensors,short-range wireless communication,artificial intelligence and intelligent interaction techniques.This work also mentions the challenges and opportunities for the industry,pointing out how to innovate and dominate the furniture market in the era of transformation from the traditional furniture industry to intelligent upgrading.The results are proposed to help readers from all over the world to understand the development trend and progress of the Chinese intelligent furniture industry.展开更多
Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future developmen...Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future development of high-speed rail technology.Design/methodology/approach–This paper elaborates on the demand and significance of developing high-speed maglev technology worldwide and examines the current status and technological maturity of several major high-speed maglev systems globally.Findings–This paper summarizes the challenges in the development of high-speed maglev railways in China.Based on this analysis,it puts forward considerations for future research on high-speed maglev railways.Originality/value–This paper describes the development status and technical maturity of several major high-speed maglev systems in the world for the first time,summarizes the existing problems in the development of China’s high-speed maglev railway and on this basis,puts forward the thinking of the next research of China’s high-speed maglev railway.展开更多
The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity ...The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity and mortality remain high,and many patients progress to end-stage heart failure.Heart transplantation has become standard treatment for selected patients with end-stage heart failure,though challenges still exist.However,multiple advances over the past few years will improve the survival and quality-of-life of heart transplant recipients.This article elaborates on the specific characteristics of heart transplantation in China,the current issues,development trends,and related experiences with heart transplantation in Wuhan Union Hospital.展开更多
Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improve...Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improvement. Although homology-directed repair(HDR)is a feasible approach to achieve precise gene replacement and base substitution in some plant species, the dominance of the non-homologous end joining pathway and low efficiency of HDR in plant cells have limited its application. Base editing has emerged as an alternative tool to HDR-mediated replacement, facilitating precise editing of plant genome by converting one single base to another in a programmable manner without a doublestranded break and a donor repair template. In this review, we summarize the latest developments in base-editing technologies as well as their underlying mechanisms. We review current applications of these technologies in plant species. Finally, we address the challenges and future perspectives of this emerging technology in plants.展开更多
Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean w...Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean was first introduced to SSA by Chinese traders in the19 th century and was cultivated as an economic crop as early as 1903 in South Africa. In the past four decades, soybean cultivation area and production in SSA has increased exponentially, from about 20,000 ha and 13,000 t in the early 1970 s to 1,500,000 ha and2,300,000 t in 2016. Soybean yield has been stagnant in SSA for decades at about 1.1 t ha^(-1),much lower than the world average, representing one of the most challenging issues in the soybean industry in SSA. The low soybean yield in SSA can be attributed to the use of poorperforming varieties and to the limited application of fertilizers and rhizobial inoculants in soils with no history of soybean production. South Africa, Nigeria, Zambia, and Uganda are the leading soybean producers in SSA. Soybean research in SSA is conducted by international and national research institutions, including IITA, national soybean improvement programs, universities, and the private sector. Between 1970 and 2011, 195 soybean varieties were released by IITA, private breeders, and national soybean improvement programs in SSA. This paper reviews the history and current state of soybean production and of the utilization and adoption of tropical varieties in SSA, addresses the major soybean yield-limiting factors across the region, and discusses the potential of the soybean industry in SSA. It also highlights soybean improvement efforts and lessons learned from previous soybean improvement efforts and the current progress of some national soybean improvement programs in SSA. Opportunities for scaling up tropical soybean as a major crop across SSA countries are promising.展开更多
Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory disease, leading toa great number of death and a huge disease burden to China. Recently, as the promulgation of a series of nation...Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory disease, leading toa great number of death and a huge disease burden to China. Recently, as the promulgation of a series of national healthpolicies, the diagnosis and treatment of COPD has gradually gained attention. The prevention and treatment capacity ofCOPD in China has been greatly improved, but there are still problems of insufficient diagnosis and irregular treatment. Theproblem is mainly related to the lack of universal pulmonary function test, insufficient number and level of doctors, and thenonstandard use of drugs. The prevention and treatment of COPD in primary medical institutions is particularly lacking. Inorder to promote the prevention and treatment of COPD, China has innovatively adopted a number of measures, including"Happy Breathing" project, standardized diagnosis and treatment system and capacity building for respiratory diseases inprimary medical institutions, el at. Effective progress has been made through these methods, and great improvement of theprevention, diagnosis and treatment of COPD has been achieved.展开更多
Introduction Dr.Ching-Yu Cheng(Figure 1)is currently an Associate Professor of the Academic Medicine Research Institute and the Academic Clinical Program for Ophthalmology and Visual Sciences(Eye ACP)at Duke-NUS Gradu...Introduction Dr.Ching-Yu Cheng(Figure 1)is currently an Associate Professor of the Academic Medicine Research Institute and the Academic Clinical Program for Ophthalmology and Visual Sciences(Eye ACP)at Duke-NUS Graduate School of Medicine;and Department of Ophthalmology,Yong Loo Lin School of Medicine,National University of Singapore.展开更多
Pancreatic cancer is the fourth leading cause of cancer death worldwide and leads to an estimated 220 000 deaths per year[1].The malignancy is difficult to detect and diagnose,as there are no noticeable signs or sympt...Pancreatic cancer is the fourth leading cause of cancer death worldwide and leads to an estimated 220 000 deaths per year[1].The malignancy is difficult to detect and diagnose,as there are no noticeable signs or symptoms in the early stages of the disease,and the pancreas is located deep in the abdomen.Surgical resection is widely accepted as the only potentially curative therapy展开更多
In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as...In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as different standard in educational management and requirements, insufficiency of trilingual teachers and unreasonableness in teacher structure, shortage both in the number and characteristics of trilingual teaching materials, lateness in the study on TETAC and insufficiency of study result, and backwardness in teaching approaches and methods, etc.展开更多
The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as governm...The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as government begin to attach importance to it.There is a hospice and palliative care movement now in China.This article gives an overview of the progress and the current status in multiple aspects of hospice and palliative care in China's Mainland,and points out the barriers and challenges for its further development in the future.展开更多
文摘Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mongolian medicine combined with external application for treatment,combination of Mongolian medicine acupuncture therapy and oral administration of Mongolian medicine for treatment,integrated treatment of Mongolian and Western medicine,and combination therapy of Mongolian and traditional Chinese medicine,providing new ideas and choices for clinical research.
基金Guangzhou Planned Project of Science and Technology,No.2023A04J0612。
文摘Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.
基金support from National Key Research&Design Program of China(2018YFD0600304)Postgraduate Education Reform Project of Jiangsu Province(JGLX18_101)Technology Innovation Alliance of Wood/Bamboo Industry(TIAWBI201808).
文摘In this work,the current status,technical capabilities,and development trends of the Chinese intelligent furniture industry were in focus.Based on combining a literature review with field investigations and analysis of major scientific research projects in Zhejiang Province,China,an in-depth overview and discussion about previous experience,features,technologies,products and control methods in the intelligent furniture industry in China were conducted.The key technologies in current Chinese intelligent furniture industry include embedded systems,sensors,short-range wireless communication,artificial intelligence and intelligent interaction techniques.This work also mentions the challenges and opportunities for the industry,pointing out how to innovate and dominate the furniture market in the era of transformation from the traditional furniture industry to intelligent upgrading.The results are proposed to help readers from all over the world to understand the development trend and progress of the Chinese intelligent furniture industry.
基金This paper was supported by the funding of Strategic research and consulting project of Chinese Academy of Engineering(Grant No.2022-XBZD-20).
文摘Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future development of high-speed rail technology.Design/methodology/approach–This paper elaborates on the demand and significance of developing high-speed maglev technology worldwide and examines the current status and technological maturity of several major high-speed maglev systems globally.Findings–This paper summarizes the challenges in the development of high-speed maglev railways in China.Based on this analysis,it puts forward considerations for future research on high-speed maglev railways.Originality/value–This paper describes the development status and technical maturity of several major high-speed maglev systems in the world for the first time,summarizes the existing problems in the development of China’s high-speed maglev railway and on this basis,puts forward the thinking of the next research of China’s high-speed maglev railway.
文摘The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity and mortality remain high,and many patients progress to end-stage heart failure.Heart transplantation has become standard treatment for selected patients with end-stage heart failure,though challenges still exist.However,multiple advances over the past few years will improve the survival and quality-of-life of heart transplant recipients.This article elaborates on the specific characteristics of heart transplantation in China,the current issues,development trends,and related experiences with heart transplantation in Wuhan Union Hospital.
基金partly funded by the Transgenesis Initiative Project supported by the Ministry of Agriculture and Rural Affairs of China(2019ZX08010001,2019ZX08010003)the Central Non-Profit Fundamental Research Funding supported by the Institute of Crop Sciences,Chinese Academy of Agricultural Sciences(S2018QY05)。
文摘Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improvement. Although homology-directed repair(HDR)is a feasible approach to achieve precise gene replacement and base substitution in some plant species, the dominance of the non-homologous end joining pathway and low efficiency of HDR in plant cells have limited its application. Base editing has emerged as an alternative tool to HDR-mediated replacement, facilitating precise editing of plant genome by converting one single base to another in a programmable manner without a doublestranded break and a donor repair template. In this review, we summarize the latest developments in base-editing technologies as well as their underlying mechanisms. We review current applications of these technologies in plant species. Finally, we address the challenges and future perspectives of this emerging technology in plants.
基金supported by the Agricultural Science and Technology Innovation Program of CAAS and China Agriculture Research System (CARS-04) awarded to T.Han of CAAS and S.E.Ibrahim of Agricultural Research Corporation(ARC)Soybean Research Program,Wad Medani,Sudan
文摘Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean was first introduced to SSA by Chinese traders in the19 th century and was cultivated as an economic crop as early as 1903 in South Africa. In the past four decades, soybean cultivation area and production in SSA has increased exponentially, from about 20,000 ha and 13,000 t in the early 1970 s to 1,500,000 ha and2,300,000 t in 2016. Soybean yield has been stagnant in SSA for decades at about 1.1 t ha^(-1),much lower than the world average, representing one of the most challenging issues in the soybean industry in SSA. The low soybean yield in SSA can be attributed to the use of poorperforming varieties and to the limited application of fertilizers and rhizobial inoculants in soils with no history of soybean production. South Africa, Nigeria, Zambia, and Uganda are the leading soybean producers in SSA. Soybean research in SSA is conducted by international and national research institutions, including IITA, national soybean improvement programs, universities, and the private sector. Between 1970 and 2011, 195 soybean varieties were released by IITA, private breeders, and national soybean improvement programs in SSA. This paper reviews the history and current state of soybean production and of the utilization and adoption of tropical varieties in SSA, addresses the major soybean yield-limiting factors across the region, and discusses the potential of the soybean industry in SSA. It also highlights soybean improvement efforts and lessons learned from previous soybean improvement efforts and the current progress of some national soybean improvement programs in SSA. Opportunities for scaling up tropical soybean as a major crop across SSA countries are promising.
基金CAMS Innovation Fund for Medical Sciences (CIFMS)(No. 2018-I2M-1-001)National Key R&D Program of China, Ministry ofScience and Technology of China(No. 2016YFC1303901)。
文摘Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory disease, leading toa great number of death and a huge disease burden to China. Recently, as the promulgation of a series of national healthpolicies, the diagnosis and treatment of COPD has gradually gained attention. The prevention and treatment capacity ofCOPD in China has been greatly improved, but there are still problems of insufficient diagnosis and irregular treatment. Theproblem is mainly related to the lack of universal pulmonary function test, insufficient number and level of doctors, and thenonstandard use of drugs. The prevention and treatment of COPD in primary medical institutions is particularly lacking. Inorder to promote the prevention and treatment of COPD, China has innovatively adopted a number of measures, including"Happy Breathing" project, standardized diagnosis and treatment system and capacity building for respiratory diseases inprimary medical institutions, el at. Effective progress has been made through these methods, and great improvement of theprevention, diagnosis and treatment of COPD has been achieved.
文摘Introduction Dr.Ching-Yu Cheng(Figure 1)is currently an Associate Professor of the Academic Medicine Research Institute and the Academic Clinical Program for Ophthalmology and Visual Sciences(Eye ACP)at Duke-NUS Graduate School of Medicine;and Department of Ophthalmology,Yong Loo Lin School of Medicine,National University of Singapore.
文摘Pancreatic cancer is the fourth leading cause of cancer death worldwide and leads to an estimated 220 000 deaths per year[1].The malignancy is difficult to detect and diagnose,as there are no noticeable signs or symptoms in the early stages of the disease,and the pancreas is located deep in the abdomen.Surgical resection is widely accepted as the only potentially curative therapy
文摘In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as different standard in educational management and requirements, insufficiency of trilingual teachers and unreasonableness in teacher structure, shortage both in the number and characteristics of trilingual teaching materials, lateness in the study on TETAC and insufficiency of study result, and backwardness in teaching approaches and methods, etc.
基金supported by the Educational Reform Project of Peking Union Medical College(2015zlgc0120)
文摘The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as government begin to attach importance to it.There is a hospice and palliative care movement now in China.This article gives an overview of the progress and the current status in multiple aspects of hospice and palliative care in China's Mainland,and points out the barriers and challenges for its further development in the future.
