This paper deals with the numerical implementation of the exponential Drucker-Parger plasticitymodel in the commercial finite element software,ABAQUS,via user subroutine UMAT for adhesive joint simulations.The influen...This paper deals with the numerical implementation of the exponential Drucker-Parger plasticitymodel in the commercial finite element software,ABAQUS,via user subroutine UMAT for adhesive joint simulations.The influence of hydrostatic pressure on adhesive strength was investigated by a modified Arcan fixture designed particularly to induce a different state of hydrostatic pressure within an adhesive layer.The developed user subroutine UMAT,which utilizes an associated plastic flow during a plastic deformation,can provide a good agreement between the simulations and the experimental data.Better numerical stability at highly positive hydrostatic pressure loads for a very high order of exponential function can also be achieved compared to when a non-associated flow is used.展开更多
Compaction process simulation and residual stress prediction of green PM compact were carried out with elasto-plastic 3D FEA based on the modified Drueker-Prager Cap model in Abaqus. The model parameters of the invest...Compaction process simulation and residual stress prediction of green PM compact were carried out with elasto-plastic 3D FEA based on the modified Drueker-Prager Cap model in Abaqus. The model parameters of the investigated powder Distaloy AE were determined as functions of relative density through typical mechanical property tests of powder. The model was implemented as a user subroutine USDFLD. Single sided compaction of a d20 ram^5 mm disk green compact of Distaloy AE was simulated, and the residual stress of the disk after ejection was predicted with FEA. The FEA results of the compaction process and the residual stress of the disk show good agreement with compaction experiments and X-ray diffraction measurements, which validates the model and its parameters. The results indicate that the compressive residual stresses exist mainly in a thin layer on the side surface, but the residual stresses are very small on the top and bottom surfaces.展开更多
A constitutive model for methane hydrate-bearing sediment(MHBS)is essential for the analysis of mechanical response of MHBS to the change of hydrate saturation caused by gas extraction. A new elasto-plastic constituti...A constitutive model for methane hydrate-bearing sediment(MHBS)is essential for the analysis of mechanical response of MHBS to the change of hydrate saturation caused by gas extraction. A new elasto-plastic constitutive model is built in order to simulate the mechanical behavior of MHBS in this paper. This model represents more significant mechanical properties of MHBS such as bonding, higher stiffness, softening and stress-strain nonlinear relationship. The bonding behavior can be described by use of a parameter related to mechanical hydrate saturation. Higher stiffness can be modeled by the introduction of hydrate saturation into traditional expression of soil stiffness. Softening can be controlled by a function describing the relationship between cohesion and bonding structure factor. Dilatancy can be estimated by establishing the relationship between the lateral strain and axial strain. Meanwhile, the hypothesis of isotropic expanding is applied to the calculation of the volumetric strain. The stress-strain curves under different hydrate saturation conditions predicted by the proposed model are in good agreement with the test data. All the coefficients can be easily obtained by the triaxial test of MHBS.展开更多
In order to investigate the sand mold strength after the aeration sand filling-high pressure squeeze moldingprocess,a tree-dimentional(3D)numerical simulation was introduced.The commercial finite element method(FEM)so...In order to investigate the sand mold strength after the aeration sand filling-high pressure squeeze moldingprocess,a tree-dimentional(3D)numerical simulation was introduced.The commercial finite element method(FEM)software ABAQUScombined with a revised Drucker-Prager/Cap model was used to simulate the squeeze compaction process.Additionally,the sand bulk density after the aeration sand filling process was tested by a specially designed experiment,which divided the whole sand bulk in the molding chamber into5x9regions and it was used as the input to simulate the squeeze process.During the simulation process,the uniform modeling simulation and the patition modeling simulation methods were used a d the3D numercal simulation results were compared with correlative benchmark testings.From the3D numerica simulation results,it can be concluded that the uniform sand bulk density distribution can obtain a high quality sandmold and the revised Drncker-Pager/Cap model is suitable for handling the situation with the complex paaern.The3D numerical simulation results can predict well the sand mold strength distribution and can be used as guidelines for the production practice.展开更多
Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 km.Because they can significantly influence radio communications and navigation systems,...Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 km.Because they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite systems.In this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde observations.The deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular.展开更多
A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,t...A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,the aging rates between two age groups are set to be constant.The existence-and-uniqueness of global positive solution is firstly showed.Then,by constructing several appropriate Lyapunov functions and using the high-dimensional Itô’s formula,the sufficient conditions for the stochastic extinction and stochastic persistence of the exposed individuals and the infected individuals are obtained.The stochastic extinction indicator and the stochastic persistence indicator are less-valued expressions compared with the basic reproduction number.Meanwhile,the main results of this study are modified into multi-age groups.Furthermore,by using the surveillance data for Fujian Provincial Center for Disease Control and Prevention,Fuzhou COVID-19 epidemic is chosen to carry out the numerical simulations,which show that the age group of the population plays the vital role when studying infectious diseases.展开更多
A 3D crustal model was constructed using a combination of cutting-edge techniques,which were integrated to provide a density model for Egypt and address the sporadic distribution of seismic data.These techniques inclu...A 3D crustal model was constructed using a combination of cutting-edge techniques,which were integrated to provide a density model for Egypt and address the sporadic distribution of seismic data.These techniques include obtaining gravity data from the Gravity Field and Steady-State Ocean Circulation Explorer(GOCE),creating seismic profiles,analyzing the receiver functions of seismic data,obtaining information from boreholes,and providing geological interpretations.GOCE satellite gravity data were processed to construct a preliminary model based on nonlinear inversions of the data.A regional crustal thickness model was developed using receiver functions,seismic refraction profiles,and geological insights.The inverted model was validated using borehole data and compared with seismic estimates.The model exhibited strong consistency and revealed a correlation between crustal thickness,geology,and tectonics of Egypt.It showed that the shallowest depths of the Moho are located in the north along the Mediterranean Sea and in the eastern part along the Red Sea,reflecting an oceanic plate with a thin,high-density crust.The deepest Moho depths are located in the southwestern part of Egypt,Red Sea coastal mountains,and Sinai Peninsula.The obtained 3D model of crustal thickness provided finely detailed Moho depth estimates that aligned closely with geology and tectonic characteristics of Egypt,contributing valuable insights into the subsurface structure and tectonic processes of region.展开更多
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism rem...Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.展开更多
In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis...In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis nonlinear characteristics of piezo-positioning actuator.The static nonlinear part and dynamic linear part of the Hammerstein model are represented by models obtained through the Prandtl-Ishlinskii(PI)model and Hankel matrix system identification method,respectively.This model demonstrates good generalization capability for typical input frequencies below 200 Hz.A sliding mode inverse compensation tracking control strategy based on P-I inverse model and integral augmentation is proposed.Experimental results show that compared with PID inverse compensation control and sliding mode control without inverse compensation,the sliding mode inverse compensation control has a more ideal step response and no overshoot,moreover,the settling time is only 6.2 ms.In the frequency domain,the system closed-loop tracking bandwidth reaches 119.9 Hz,and the disturbance rejection bandwidth reaches 86.2 Hz.The proposed control strategy can effectively compensate the hysteresis nonlinearity,and improve the tracking accuracy and antidisturbance capability of piezo-positioning system.展开更多
Solar flare prediction is an important subject in the field of space weather.Deep learning technology has greatly promoted the development of this subject.In this study,we propose a novel solar flare forecasting model...Solar flare prediction is an important subject in the field of space weather.Deep learning technology has greatly promoted the development of this subject.In this study,we propose a novel solar flare forecasting model integrating Deep Residual Network(ResNet)and Support Vector Machine(SVM)for both≥C-class(C,M,and X classes)and≥M-class(M and X classes)flares.We collected samples of magnetograms from May 1,2010 to September 13,2018 from Space-weather Helioseismic and Magnetic Imager(HMI)Active Region Patches and then used a cross-validation method to obtain seven independent data sets.We then utilized five metrics to evaluate our fusion model,based on intermediate-output extracted by ResNet and SVM using the Gaussian kernel function.Our results show that the primary metric true skill statistics(TSS)achieves a value of 0.708±0.027 for≥C-class prediction,and of 0.758±0.042 for≥M-class prediction;these values indicate that our approach performs significantly better than those of previous studies.The metrics of our fusion model’s performance on the seven datasets indicate that the model is quite stable and robust,suggesting that fusion models that integrate an excellent baseline network with SVM can achieve improved performance in solar flare prediction.Besides,we also discuss the performance impact of architectural innovation in our fusion model.展开更多
To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precis...To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precisely pinpointing misfire faults.In the experiment,we established a total of 11 distinct states,encompassing the engine’s normal state,single-cylinder misfire faults,and dual-cylinder misfire faults for different cylinders.Data collection was facilitated by a highly sensitive acceleration signal collector with a high sampling rate of 20,840Hz.The collected data were methodically divided into training and testing sets based on different experimental groups to ensure generalization and prevent overlap between the two sets.The results revealed that,with a vibration acceleration sequence of 1000 time steps(approximately 50 ms)as input,the SENET model achieved a misfire fault detection accuracy of 99.8%.For comparison,we also trained and tested several commonly used models,including Long Short-Term Memory(LSTM),Transformer,and Multi-Scale Residual Networks(MSRESNET),yielding accuracy rates of 84%,79%,and 95%,respectively.This underscores the superior accuracy of the SENET model in detecting engine misfire faults compared to other models.Furthermore,the F1 scores for each type of recognition in the SENET model surpassed 0.98,outperforming the baseline models.Our analysis indicated that the misclassified samples in the LSTM and Transformer models’predictions were primarily due to intra-class misidentifications between single-cylinder and dual-cylinder misfire scenarios.To delve deeper,we conducted a visual analysis of the features extracted by the LSTM and SENET models using T-distributed Stochastic Neighbor Embedding(T-SNE)technology.The findings revealed that,in the LSTMmodel,data points of the same type tended to cluster together with significant overlap.Conversely,in the SENET model,data points of various types were more widely and evenly dispersed,demonstrating its effectiveness in distinguishing between different fault types.展开更多
This paper presents a comparative study of ARIMA and Neural Network AutoRegressive (NNAR) models for time series forecasting. The study focuses on simulated data generated using ARIMA(1, 1, 0) and applies both models ...This paper presents a comparative study of ARIMA and Neural Network AutoRegressive (NNAR) models for time series forecasting. The study focuses on simulated data generated using ARIMA(1, 1, 0) and applies both models for training and forecasting. Model performance is evaluated using MSE, AIC, and BIC. The models are further applied to neonatal mortality data from Saudi Arabia to assess their predictive capabilities. The results indicate that the NNAR model outperforms ARIMA in both training and forecasting.展开更多
Bangladesh has a denser population in comparison with many other countries. Though the rate of population increase has been regarded as a concerning issue, estimation of the population instability in the upcoming year...Bangladesh has a denser population in comparison with many other countries. Though the rate of population increase has been regarded as a concerning issue, estimation of the population instability in the upcoming years may be useful for national planning. To predict Bangladesh’s future population, this study compares the estimated populations of two popular population models, the Malthusian and the logistic population models, with the country’s census population published by BBS. We also tried to find out which model gives a better approximation for forecasting the past, present, and future population between these two models.展开更多
This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble lear...This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and AB-RBFN.Additionally,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and validation.The models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to roads.These factors were instrumental in predicting the output variable,which was the probability of landslide occurrence.Statistical analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other models.The AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of 0.926.These results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.展开更多
This study directs the discussion of HIV disease with a novel kind of complex dynamical generalized and piecewise operator in the sense of classical and Atangana Baleanu(AB)derivatives having arbitrary order.The HIV i...This study directs the discussion of HIV disease with a novel kind of complex dynamical generalized and piecewise operator in the sense of classical and Atangana Baleanu(AB)derivatives having arbitrary order.The HIV infection model has a susceptible class,a recovered class,along with a case of infection divided into three sub-different levels or categories and the recovered class.The total time interval is converted into two,which are further investigated for ordinary and fractional order operators of the AB derivative,respectively.The proposed model is tested separately for unique solutions and existence on bi intervals.The numerical solution of the proposed model is treated by the piece-wise numerical iterative scheme of Newtons Polynomial.The proposed method is established for piece-wise derivatives under natural order and non-singular Mittag-Leffler Law.The cross-over or bending characteristics in the dynamical system of HIV are easily examined by the aspect of this research having a memory effect for controlling the said disease.This study uses the neural network(NN)technique to obtain a better set of weights with low residual errors,and the epochs number is considered 1000.The obtained figures represent the approximate solution and absolute error which are tested with NN to train the data accurately.展开更多
基金funded by King Mongkut’s University of Technology North Bangkok.Contract No.KMUTNB-PHD-62-07.
文摘This paper deals with the numerical implementation of the exponential Drucker-Parger plasticitymodel in the commercial finite element software,ABAQUS,via user subroutine UMAT for adhesive joint simulations.The influence of hydrostatic pressure on adhesive strength was investigated by a modified Arcan fixture designed particularly to induce a different state of hydrostatic pressure within an adhesive layer.The developed user subroutine UMAT,which utilizes an associated plastic flow during a plastic deformation,can provide a good agreement between the simulations and the experimental data.Better numerical stability at highly positive hydrostatic pressure loads for a very high order of exponential function can also be achieved compared to when a non-associated flow is used.
基金Project(2009ZX04004-031-04) supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China
文摘Compaction process simulation and residual stress prediction of green PM compact were carried out with elasto-plastic 3D FEA based on the modified Drueker-Prager Cap model in Abaqus. The model parameters of the investigated powder Distaloy AE were determined as functions of relative density through typical mechanical property tests of powder. The model was implemented as a user subroutine USDFLD. Single sided compaction of a d20 ram^5 mm disk green compact of Distaloy AE was simulated, and the residual stress of the disk after ejection was predicted with FEA. The FEA results of the compaction process and the residual stress of the disk show good agreement with compaction experiments and X-ray diffraction measurements, which validates the model and its parameters. The results indicate that the compressive residual stresses exist mainly in a thin layer on the side surface, but the residual stresses are very small on the top and bottom surfaces.
基金Supported by the National Science and Technology Major Project of China(No.2011ZX05026-004)the National Natural Science Foundation of China(No.51309047 and No.51509032)
文摘A constitutive model for methane hydrate-bearing sediment(MHBS)is essential for the analysis of mechanical response of MHBS to the change of hydrate saturation caused by gas extraction. A new elasto-plastic constitutive model is built in order to simulate the mechanical behavior of MHBS in this paper. This model represents more significant mechanical properties of MHBS such as bonding, higher stiffness, softening and stress-strain nonlinear relationship. The bonding behavior can be described by use of a parameter related to mechanical hydrate saturation. Higher stiffness can be modeled by the introduction of hydrate saturation into traditional expression of soil stiffness. Softening can be controlled by a function describing the relationship between cohesion and bonding structure factor. Dilatancy can be estimated by establishing the relationship between the lateral strain and axial strain. Meanwhile, the hypothesis of isotropic expanding is applied to the calculation of the volumetric strain. The stress-strain curves under different hydrate saturation conditions predicted by the proposed model are in good agreement with the test data. All the coefficients can be easily obtained by the triaxial test of MHBS.
基金The National Natural Science Foundation of China(No.51575304)the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2012ZX04012011)
文摘In order to investigate the sand mold strength after the aeration sand filling-high pressure squeeze moldingprocess,a tree-dimentional(3D)numerical simulation was introduced.The commercial finite element method(FEM)software ABAQUScombined with a revised Drucker-Prager/Cap model was used to simulate the squeeze compaction process.Additionally,the sand bulk density after the aeration sand filling process was tested by a specially designed experiment,which divided the whole sand bulk in the molding chamber into5x9regions and it was used as the input to simulate the squeeze process.During the simulation process,the uniform modeling simulation and the patition modeling simulation methods were used a d the3D numercal simulation results were compared with correlative benchmark testings.From the3D numerica simulation results,it can be concluded that the uniform sand bulk density distribution can obtain a high quality sandmold and the revised Drncker-Pager/Cap model is suitable for handling the situation with the complex paaern.The3D numerical simulation results can predict well the sand mold strength distribution and can be used as guidelines for the production practice.
基金supported by the Project of Stable Support for Youth Team in Basic Research Field,CAS(grant No.YSBR-018)the National Natural Science Foundation of China(grant Nos.42188101,42130204)+4 种基金the B-type Strategic Priority Program of CAS(grant no.XDB41000000)the National Natural Science Foundation of China(NSFC)Distinguished Overseas Young Talents Program,Innovation Program for Quantum Science and Technology(2021ZD0300301)the Open Research Project of Large Research Infrastructures of CAS-“Study on the interaction between low/mid-latitude atmosphere and ionosphere based on the Chinese Meridian Project”.The project was supported also by the National Key Laboratory of Deep Space Exploration(Grant No.NKLDSE2023A002)the Open Fund of Anhui Provincial Key Laboratory of Intelligent Underground Detection(Grant No.APKLIUD23KF01)the China National Space Administration(CNSA)pre-research Project on Civil Aerospace Technologies No.D010305,D010301.
文摘Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 km.Because they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite systems.In this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde observations.The deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular.
基金Supported by National Natural Science Foundation of China(61911530398,12231012)Consultancy Project by the Chinese Academy of Engineering(2022-JB-06,2023-JB-12)+3 种基金the Natural Science Foundation of Fujian Province of China(2021J01621)Special Projects of the Central Government Guiding Local Science and Technology Development(2021L3018)Royal Society of Edinburgh(RSE1832)Engineering and Physical Sciences Research Council(EP/W522521/1).
文摘A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,the aging rates between two age groups are set to be constant.The existence-and-uniqueness of global positive solution is firstly showed.Then,by constructing several appropriate Lyapunov functions and using the high-dimensional Itô’s formula,the sufficient conditions for the stochastic extinction and stochastic persistence of the exposed individuals and the infected individuals are obtained.The stochastic extinction indicator and the stochastic persistence indicator are less-valued expressions compared with the basic reproduction number.Meanwhile,the main results of this study are modified into multi-age groups.Furthermore,by using the surveillance data for Fujian Provincial Center for Disease Control and Prevention,Fuzhou COVID-19 epidemic is chosen to carry out the numerical simulations,which show that the age group of the population plays the vital role when studying infectious diseases.
文摘A 3D crustal model was constructed using a combination of cutting-edge techniques,which were integrated to provide a density model for Egypt and address the sporadic distribution of seismic data.These techniques include obtaining gravity data from the Gravity Field and Steady-State Ocean Circulation Explorer(GOCE),creating seismic profiles,analyzing the receiver functions of seismic data,obtaining information from boreholes,and providing geological interpretations.GOCE satellite gravity data were processed to construct a preliminary model based on nonlinear inversions of the data.A regional crustal thickness model was developed using receiver functions,seismic refraction profiles,and geological insights.The inverted model was validated using borehole data and compared with seismic estimates.The model exhibited strong consistency and revealed a correlation between crustal thickness,geology,and tectonics of Egypt.It showed that the shallowest depths of the Moho are located in the north along the Mediterranean Sea and in the eastern part along the Red Sea,reflecting an oceanic plate with a thin,high-density crust.The deepest Moho depths are located in the southwestern part of Egypt,Red Sea coastal mountains,and Sinai Peninsula.The obtained 3D model of crustal thickness provided finely detailed Moho depth estimates that aligned closely with geology and tectonic characteristics of Egypt,contributing valuable insights into the subsurface structure and tectonic processes of region.
文摘Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.
文摘In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis nonlinear characteristics of piezo-positioning actuator.The static nonlinear part and dynamic linear part of the Hammerstein model are represented by models obtained through the Prandtl-Ishlinskii(PI)model and Hankel matrix system identification method,respectively.This model demonstrates good generalization capability for typical input frequencies below 200 Hz.A sliding mode inverse compensation tracking control strategy based on P-I inverse model and integral augmentation is proposed.Experimental results show that compared with PID inverse compensation control and sliding mode control without inverse compensation,the sliding mode inverse compensation control has a more ideal step response and no overshoot,moreover,the settling time is only 6.2 ms.In the frequency domain,the system closed-loop tracking bandwidth reaches 119.9 Hz,and the disturbance rejection bandwidth reaches 86.2 Hz.The proposed control strategy can effectively compensate the hysteresis nonlinearity,and improve the tracking accuracy and antidisturbance capability of piezo-positioning system.
基金supported by the National Key R&D Program of China (Grant No.2022YFF0503700)the National Natural Science Foundation of China (42074196, 41925018)
文摘Solar flare prediction is an important subject in the field of space weather.Deep learning technology has greatly promoted the development of this subject.In this study,we propose a novel solar flare forecasting model integrating Deep Residual Network(ResNet)and Support Vector Machine(SVM)for both≥C-class(C,M,and X classes)and≥M-class(M and X classes)flares.We collected samples of magnetograms from May 1,2010 to September 13,2018 from Space-weather Helioseismic and Magnetic Imager(HMI)Active Region Patches and then used a cross-validation method to obtain seven independent data sets.We then utilized five metrics to evaluate our fusion model,based on intermediate-output extracted by ResNet and SVM using the Gaussian kernel function.Our results show that the primary metric true skill statistics(TSS)achieves a value of 0.708±0.027 for≥C-class prediction,and of 0.758±0.042 for≥M-class prediction;these values indicate that our approach performs significantly better than those of previous studies.The metrics of our fusion model’s performance on the seven datasets indicate that the model is quite stable and robust,suggesting that fusion models that integrate an excellent baseline network with SVM can achieve improved performance in solar flare prediction.Besides,we also discuss the performance impact of architectural innovation in our fusion model.
基金Yongxian Huang supported by Projects of Guangzhou Science and Technology Plan(2023A04J0409)。
文摘To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precisely pinpointing misfire faults.In the experiment,we established a total of 11 distinct states,encompassing the engine’s normal state,single-cylinder misfire faults,and dual-cylinder misfire faults for different cylinders.Data collection was facilitated by a highly sensitive acceleration signal collector with a high sampling rate of 20,840Hz.The collected data were methodically divided into training and testing sets based on different experimental groups to ensure generalization and prevent overlap between the two sets.The results revealed that,with a vibration acceleration sequence of 1000 time steps(approximately 50 ms)as input,the SENET model achieved a misfire fault detection accuracy of 99.8%.For comparison,we also trained and tested several commonly used models,including Long Short-Term Memory(LSTM),Transformer,and Multi-Scale Residual Networks(MSRESNET),yielding accuracy rates of 84%,79%,and 95%,respectively.This underscores the superior accuracy of the SENET model in detecting engine misfire faults compared to other models.Furthermore,the F1 scores for each type of recognition in the SENET model surpassed 0.98,outperforming the baseline models.Our analysis indicated that the misclassified samples in the LSTM and Transformer models’predictions were primarily due to intra-class misidentifications between single-cylinder and dual-cylinder misfire scenarios.To delve deeper,we conducted a visual analysis of the features extracted by the LSTM and SENET models using T-distributed Stochastic Neighbor Embedding(T-SNE)technology.The findings revealed that,in the LSTMmodel,data points of the same type tended to cluster together with significant overlap.Conversely,in the SENET model,data points of various types were more widely and evenly dispersed,demonstrating its effectiveness in distinguishing between different fault types.
文摘This paper presents a comparative study of ARIMA and Neural Network AutoRegressive (NNAR) models for time series forecasting. The study focuses on simulated data generated using ARIMA(1, 1, 0) and applies both models for training and forecasting. Model performance is evaluated using MSE, AIC, and BIC. The models are further applied to neonatal mortality data from Saudi Arabia to assess their predictive capabilities. The results indicate that the NNAR model outperforms ARIMA in both training and forecasting.
文摘Bangladesh has a denser population in comparison with many other countries. Though the rate of population increase has been regarded as a concerning issue, estimation of the population instability in the upcoming years may be useful for national planning. To predict Bangladesh’s future population, this study compares the estimated populations of two popular population models, the Malthusian and the logistic population models, with the country’s census population published by BBS. We also tried to find out which model gives a better approximation for forecasting the past, present, and future population between these two models.
基金the University of Transport Technology under the project entitled“Application of Machine Learning Algorithms in Landslide Susceptibility Mapping in Mountainous Areas”with grant number DTTD2022-16.
文摘This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and AB-RBFN.Additionally,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and validation.The models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to roads.These factors were instrumental in predicting the output variable,which was the probability of landslide occurrence.Statistical analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other models.The AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of 0.926.These results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.
基金supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University(IMSIU)(grant number IMSIU-RP23066).
文摘This study directs the discussion of HIV disease with a novel kind of complex dynamical generalized and piecewise operator in the sense of classical and Atangana Baleanu(AB)derivatives having arbitrary order.The HIV infection model has a susceptible class,a recovered class,along with a case of infection divided into three sub-different levels or categories and the recovered class.The total time interval is converted into two,which are further investigated for ordinary and fractional order operators of the AB derivative,respectively.The proposed model is tested separately for unique solutions and existence on bi intervals.The numerical solution of the proposed model is treated by the piece-wise numerical iterative scheme of Newtons Polynomial.The proposed method is established for piece-wise derivatives under natural order and non-singular Mittag-Leffler Law.The cross-over or bending characteristics in the dynamical system of HIV are easily examined by the aspect of this research having a memory effect for controlling the said disease.This study uses the neural network(NN)technique to obtain a better set of weights with low residual errors,and the epochs number is considered 1000.The obtained figures represent the approximate solution and absolute error which are tested with NN to train the data accurately.
