Dear Editor,We report a case of recurrence after spontaneous separation of epiretinal membrane (ERM) in a young woman with suspected retinal vasculitis.ERM is defined as the fibrocellular membrane that proliferates on...Dear Editor,We report a case of recurrence after spontaneous separation of epiretinal membrane (ERM) in a young woman with suspected retinal vasculitis.ERM is defined as the fibrocellular membrane that proliferates on the inner surface of neurosensory retina at the macular area.Idiopathic ERM(iERM) usually occurs without a clearly identifiable cause in patients of more than 50 years of age and a great discrepancy in its prevalence from 1.02%to 28.9%among different ethnic groups were noted in previous epidemiologic studies^([1-3]).展开更多
The FDA has recently approved Krystal biotech's beremagene gep erpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the tre...The FDA has recently approved Krystal biotech's beremagene gep erpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the treatment of this devastating disease, but also for the whole field of non-replicative (nr) recombinant HSV-1vectors for gene therapy. To view this Bench to Bedside, open or download the PDF.展开更多
目的观察小牛血去蛋白提取物眼凝胶对机械法准分子激光上皮瓣下角膜磨镶术(epipolis laser in situ keratomileusis,Epi-LASIK)术后角膜上皮修复的影响,评价其有效性与安全性。方法79例(158眼)接受Epi-LASIK的患者随机分为2组,对照组40...目的观察小牛血去蛋白提取物眼凝胶对机械法准分子激光上皮瓣下角膜磨镶术(epipolis laser in situ keratomileusis,Epi-LASIK)术后角膜上皮修复的影响,评价其有效性与安全性。方法79例(158眼)接受Epi-LASIK的患者随机分为2组,对照组40例(80眼)术后常规给予3g.L-1泰利必妥滴眼液、1g.L-1氟美瞳滴眼液和泪然滴眼液滴眼,每天4次,共7d,之后常规滴用人工泪液和皮质类固醇滴眼液;试验组39例(78眼)给予3g.L-1泰利必妥滴眼液、1g.L-1氟美瞳滴眼液和泪然眼液滴眼,并加用小牛血去蛋白提取物眼凝胶,每天4次,共7d,之后常规滴用人工泪液和皮质类固醇滴眼液。术后随访6个月,定期观察2组患者术后疼痛反应、角膜上皮愈合时间、视力、等效球镜度数及角膜上皮下雾状混浊(haze)情况。结果术后第1天和第2天试验组疼痛程度评分为1.50±0.43和1.03±0.61,对照组为2.02±0.44和1.60±0.57,试验组疼痛程度均明显轻于对照组(均为P<0.05)。试验组角膜上皮愈合平均时间为(3.01±1.36)d,对照组为(4.08±1.59)d,试验组明显短于对照组(t=4.54,P<0.05)。2组患眼术后视力恢复、等效球镜度数和haze情况差异均无统计学意义(均为P>0.05)。结论Epi-LASIK术后短期应用小牛血去蛋白提取物眼凝胶能够减轻术后疼痛症状,加快角膜上皮愈合,并且安全、无毒副作用。展开更多
基金Supported by Beijing Natural Science Foundation (No.J190005)。
文摘Dear Editor,We report a case of recurrence after spontaneous separation of epiretinal membrane (ERM) in a young woman with suspected retinal vasculitis.ERM is defined as the fibrocellular membrane that proliferates on the inner surface of neurosensory retina at the macular area.Idiopathic ERM(iERM) usually occurs without a clearly identifiable cause in patients of more than 50 years of age and a great discrepancy in its prevalence from 1.02%to 28.9%among different ethnic groups were noted in previous epidemiologic studies^([1-3]).
文摘The FDA has recently approved Krystal biotech's beremagene gep erpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the treatment of this devastating disease, but also for the whole field of non-replicative (nr) recombinant HSV-1vectors for gene therapy. To view this Bench to Bedside, open or download the PDF.
文摘目的观察小牛血去蛋白提取物眼凝胶对机械法准分子激光上皮瓣下角膜磨镶术(epipolis laser in situ keratomileusis,Epi-LASIK)术后角膜上皮修复的影响,评价其有效性与安全性。方法79例(158眼)接受Epi-LASIK的患者随机分为2组,对照组40例(80眼)术后常规给予3g.L-1泰利必妥滴眼液、1g.L-1氟美瞳滴眼液和泪然滴眼液滴眼,每天4次,共7d,之后常规滴用人工泪液和皮质类固醇滴眼液;试验组39例(78眼)给予3g.L-1泰利必妥滴眼液、1g.L-1氟美瞳滴眼液和泪然眼液滴眼,并加用小牛血去蛋白提取物眼凝胶,每天4次,共7d,之后常规滴用人工泪液和皮质类固醇滴眼液。术后随访6个月,定期观察2组患者术后疼痛反应、角膜上皮愈合时间、视力、等效球镜度数及角膜上皮下雾状混浊(haze)情况。结果术后第1天和第2天试验组疼痛程度评分为1.50±0.43和1.03±0.61,对照组为2.02±0.44和1.60±0.57,试验组疼痛程度均明显轻于对照组(均为P<0.05)。试验组角膜上皮愈合平均时间为(3.01±1.36)d,对照组为(4.08±1.59)d,试验组明显短于对照组(t=4.54,P<0.05)。2组患眼术后视力恢复、等效球镜度数和haze情况差异均无统计学意义(均为P>0.05)。结论Epi-LASIK术后短期应用小牛血去蛋白提取物眼凝胶能够减轻术后疼痛症状,加快角膜上皮愈合,并且安全、无毒副作用。
