Angiomyolipomas are uncommon tumors in the skin. Neoplasms with the same name are more typically associated with a renal location, many in the context of tube rous sclerosis. Three cases of cutaneous angiomyolipoma ar...Angiomyolipomas are uncommon tumors in the skin. Neoplasms with the same name are more typically associated with a renal location, many in the context of tube rous sclerosis. Three cases of cutaneous angiomyolipoma are reported, which were all HMB45 negative and not associated with tuberous sclerosis. This is the firs t series of such tumors to be stained with HMB45. The presence of fat in histolo gically similar cutaneous angioleiomyomas has been previously documented and a r eview of 40 archival cases revealed fat in 1 case. The author proposes that cuta neous angiomyolipomas should be termed angioleiomyoma with fat to avoid confusio n with unrelated non-cutaneous angiomyolipomas that are HMB45 negative and requ ire investigation for tuberous sclerosis.展开更多
用抗黑素瘤特异性单抗(HMB45)对恶性黑素瘤(MM)、色素痣和其他肿瘤组织进行染色,旨在探讨其在 MM 诊断和鉴别诊断中的作用。一、资料和方法选取 MM 54例(原发于皮肤46例,淋巴结转移性8例,其中色素性33例,无色素性21例)、色素痣13例(皮...用抗黑素瘤特异性单抗(HMB45)对恶性黑素瘤(MM)、色素痣和其他肿瘤组织进行染色,旨在探讨其在 MM 诊断和鉴别诊断中的作用。一、资料和方法选取 MM 54例(原发于皮肤46例,淋巴结转移性8例,其中色素性33例,无色素性21例)、色素痣13例(皮内痣和复合痣各5例,交界痣3例)展开更多
文摘Angiomyolipomas are uncommon tumors in the skin. Neoplasms with the same name are more typically associated with a renal location, many in the context of tube rous sclerosis. Three cases of cutaneous angiomyolipoma are reported, which were all HMB45 negative and not associated with tuberous sclerosis. This is the firs t series of such tumors to be stained with HMB45. The presence of fat in histolo gically similar cutaneous angioleiomyomas has been previously documented and a r eview of 40 archival cases revealed fat in 1 case. The author proposes that cuta neous angiomyolipomas should be termed angioleiomyoma with fat to avoid confusio n with unrelated non-cutaneous angiomyolipomas that are HMB45 negative and requ ire investigation for tuberous sclerosis.
