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Use of Network Pharmacology and Molecular Docking to Investigate the Mechanism by Which Ginseng Ameliorates Hypoxia 被引量:3
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作者 WANG Tao LI Hao Tian +7 位作者 WEI Shi Zhang CAI Hua Dan ZHU Yun LIU Hong Hong LI Yong Zhi WANG Jia Ping ZOU Wen Jun ZHAO Yan Ling 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第11期855-858,共4页
Hypoxia is a common pathological process in various clinical diseases and is characterized by abnormal changes in metabolism, function, and morphological structure of tissues resulting from insufficient oxygen supply ... Hypoxia is a common pathological process in various clinical diseases and is characterized by abnormal changes in metabolism, function, and morphological structure of tissues resulting from insufficient oxygen supply or oxygen barriers in tissues. In particular, hypoxia in vital organs such as the brain and heart is an important cause of death;. The prevention of tissue hypoxia and the 展开更多
关键词 In Use of Network Pharmacology and Molecular Docking to investigate the Mechanism by Which Ginseng Ameliorates Hypoxia FIGURE
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Propagation Properties of Backward Lamb Waves in Plate Investigated by Dynamic Photoelastic Technique 被引量:2
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作者 胡中韬 安志武 +1 位作者 廉国选 王小民 《Chinese Physics Letters》 SCIE CAS CSCD 2017年第11期45-47,共3页
The dynamic photoelastic technique is employed to visualize and quantify the propagation properties of backward Lamb waves in a plate. Higher energy leakage of second-order symmetric backward wave mode S2b in contrast... The dynamic photoelastic technique is employed to visualize and quantify the propagation properties of backward Lamb waves in a plate. Higher energy leakage of second-order symmetric backward wave mode S2b in contrast to third-order anti-symmetric backward mode A3b is shown by the dispersion curve of a plate immersed in water, and then verified by experiments. To avoid the considerable high leakage, the plate is placed in air, both group and phase velocities of modes S2b and A3b in the glass plate are experimentally measured. In comparison with the theoretical values, less than 5% errors are found in experiments. 展开更多
关键词 In Propagation Properties of Backward Lamb Waves in Plate investigated by Dynamic Photoelastic Technique
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Investigate Evaluation of Oxidative Stress and Lipid Profile in STZ-Induced Rats Treated with Antioxidant Vitamin 被引量:1
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作者 Abdella Emam Abdella Baragob Waleed Hassan AlMalki +3 位作者 Hassan Elsiddig Hassan Farag Alla Asim Ibrahim Salwa Khojali Muhammed Samia Abdella 《Pharmacology & Pharmacy》 2014年第3期272-279,共8页
The objective of this study was designed to investigate, evaluate the effect of vitamin E on streptozotocin (STZ)-induced diabetic rats by showing significant changes in blood glucose, water, food intake, lipid profil... The objective of this study was designed to investigate, evaluate the effect of vitamin E on streptozotocin (STZ)-induced diabetic rats by showing significant changes in blood glucose, water, food intake, lipid profile, serum urea and ceratinine level, and antioxidant enzyme parameters activity. Streptozotocin (STZ)-induced toxicity was studied in male Waster rats;each divided into four groups: G1, GII, GIII, and GIV. Control rats GI, rats treated with vitamin E (GII), STZ-induced diabetic rats (GIII), and STZ-induced diabetic rats treated with vitamin E (G1V). Moreover, vitamin E reduced (p < 0.05) blood glucose and urea, thus, our study improved the lipid profile (reduced the serum levels of amount of total cholesterol, LDL, VLDL, cholesterol and triacyglycerols, and increased HDL cholesterol) and increased total amount protein in STZ-induced diabetic rats (GIV). Vitamin prevented modification in the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSX-Px) and in the concentration of the lipid hydroperoxide. Finally the study suggested that vitamin E improved hyperglycaemia and dyslipidaemia while inhibiting the progression of oxidative stress in STZ-induced diabetic rats. 展开更多
关键词 investigate LIPID Profile STZ OXIDATIVE Stress VITAMIN E
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Dissociate Hb of materials plasma gathering by Autopheresis-C 200 investigate and analyse by content
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《中国输血杂志》 CAS CSCD 2001年第S1期423-,共1页
关键词 HB Dissociate Hb of materials plasma gathering by Autopheresis-C 200 investigate and analyse by content
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ISO DEVCO President investigates poverty alleviation through standardization
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《China Standardization》 2018年第1期15-15,共1页
At the invitation of SAC,ISO DEVCO President Lena Dargham investigated the targeted poverty alleviation work through standardization in China from November 21 to 25.SAC Administrator Tian Shihong introduced the povert... At the invitation of SAC,ISO DEVCO President Lena Dargham investigated the targeted poverty alleviation work through standardization in China from November 21 to 25.SAC Administrator Tian Shihong introduced the poverty alleviation work in China to Lena at their meeting. 展开更多
关键词 ISO DEVCO President investigates poverty alleviation through standardization SAC
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西藏交通警察道路执法工作的风险与防范
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作者 尼桑拉 《时代汽车》 2024年第12期184-186,共3页
西藏自治区自然、地理与气候环境复杂且特殊,道路交通环境相对恶劣,这导致当地交通警察道路执法工作面临诸多风险,包括警员人身安全和执法效能等风险。对此,文章对西藏交通警察道路执法工作风险进行了调查分析,从地区环境、警员安全意... 西藏自治区自然、地理与气候环境复杂且特殊,道路交通环境相对恶劣,这导致当地交通警察道路执法工作面临诸多风险,包括警员人身安全和执法效能等风险。对此,文章对西藏交通警察道路执法工作风险进行了调查分析,从地区环境、警员安全意识与技能、执法装备、社会宣传和教育等角度探讨了相关风险的成因,针对性相关风险成因,提出从优化警力配置与道路信息推送、加强警员培训、完善警务装备、加强法治化宣传教育等工作来消除相关风险,以期保障警员安全并改善西藏交通环境。 展开更多
关键词 西藏 道路执法 信息推送 警用装备 法治化 harsh which leads to the local traffic POLICE road LAW ENFORCEMENT work to face a lot of RISKS including the personal SAFETY of the POLICE officers and LAW ENFORCEMENT effectiveness and other risks. In this regard this paper investigates and analyzes the RISKS of road LAW ENFORCEMENT work of the Xi Zang traffic POLICE discusses the causes of the RISKS from the perspectives of regional environment POLICE SAFETY awareness and skills LAW ENFORCEMENT equipment social publicity and education and proposes to eliminate the RISKS by optimizing the allocation of POLICE force and road information delivery strengthening POLICE training improving POLICE equipment and strengthening the rule of LAW publicity and education etc. so as to guarantee the SAFETY of POLICE officers and improve the effectiveness of LAW ENFORCEMENT so as to ensure the SAFETY of POLICE officers and improve the traffic environment in Xi Zang.
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Experimental investigation on coal pore-fracture variation and fractal characteristics synergistically affected by solvents for improving clean gas extraction 被引量:1
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作者 Feilin Han Sheng Xue +3 位作者 Chunshan Zheng Zhongwei Chen Guofu Li Bingyou Jiang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期413-425,共13页
Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal... Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal synergistically affected by solvents have not been fully understood.Ultrasonic testing,nuclear magnetic resonance analysis,liquid phase mass spectrometry was adopted to comprehensively analyze pore-fracture change characteristics of lean coal treated by combined solvent(NMP and CS_(2)).Meanwhile,quantitative characterization of above changing properties was conducted using geometric fractal theory.Relationship model between permeability,fractal dimension and porosity were established.Results indicate that the end face fractures of coal are well developed after CS2and combined solvent treatments,of which,end face box-counting fractal dimensions range from 1.1227 to 1.4767.Maximum decreases in ultrasonic longitudinal wave velocity of coal affected by NMP,CS_(2)and combined solvent are 2.700%,20.521%,22.454%,respectively.Solvent treatments could lead to increasing amount of both mesopores and macropores.Decrease ratio of fractal dimension Dsis 0.259%–2.159%,while permeability increases ratio of NMR ranges from 0.1904 to 6.4486.Meanwhile,combined solvent could dissolve coal polar and non-polar small molecules and expand flow space.Results could provide reference for solvent selection and parameter optimization of permeability-enhancement technology. 展开更多
关键词 Clean gas extraction Chemical solvent Experimental investigation Fractal characteristics Pore fracture
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Investigation of the epidemiology,pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023 被引量:1
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作者 Qinghua Shang Wenhui Gao +7 位作者 Xiangting Zhang Jianqing Zhao Ying Wu Haoqi Li Ming Zhou Zhen F.Fu Chengguang Zhang Ling Zhao 《Animal Diseases》 CAS 2024年第3期156-172,共17页
Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially availa... Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially available vaccine.Live vaccines containing Bb that are widely used abroad are generally efective but can establish latency and potentially reactivate to cause illness in some immunodefcient vaccinated recipients,raising safety concerns.In this study,34 canine-derived and two feline-derived Bb strains were isolated from 1809 canine and 113 feline nasopharyngeal swab samples collected from eight provinces in China from 2021 to 2023.The PCR results showed that the percentage of positive Bb was 22.94%(441/1922),and more than 90%of the Bb isolates had four virulence factor-encoding genes(VFGs),namely,fhaB,prn,betA and dnt.All the isolated strains displayed a multidrug-resistant phenotype.The virulence of 10 Bb strains isolated from dogs with respiratory symptoms was tested in mice,and we found that eight isolates were highly virulent.Furthermore,the eight Bb isolates with high virulence were inactivated and intramuscularly injected into mice,and three Bb strains(WH1218,WH1203 and WH1224)with the best protective efcacy were selected.Dogs immunized with these three strains exhibited strong protection against challenge with the Bb feld strain WH1218.Ultimately,the WH1218 strain with the greatest protection in dogs was selected as the vaccine candidate.Dogs and cats that received a vaccine containing 109 CFU of the inactivated WH1218 strain showed complete protection against challenge with the Bb feld strain WH1218.This study revealed that Bb is an important pathogen that causes respiratory diseases in domestic dogs and cats in China,and all the isolates exhibited multidrug resistance.The present work contributes to the current understanding of the prevalence,antimicrobial resistance,and virulence genes of Bb in domestic dogs and cats.Additionally,our results suggest that the WH1218 strain is a promising candidate safe and efcacious inactivated Bb vaccine. 展开更多
关键词 Bordetella bronchiseptica Epidemiological investigation PATHOGENICITY IMMUNOGENICITY Inactivated vaccine
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Relationship between Kawasaki disease and abdominal pain 被引量:1
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作者 Yan Pan Fu-Yong Jiao 《World Journal of Clinical Cases》 SCIE 2024年第17期2932-2934,共3页
This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral muco... This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral mucosal changes,and swelling of the extremities.This editorial aims to delve into the intricate relationship between KD and abdominal pain,drawing insights from recent research findings to provide a comprehensive understanding and potential avenues for future investigation. 展开更多
关键词 Kawasaki disease Abdominal pain RELATIONSHIP RESEARCH INVESTIGATION
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Experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering boundary effect
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作者 Xuwei Wang Yeshuang Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期1072-1084,共13页
The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundar... The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundary effect is conducted,where the hydraulic head difference(DH)varies,and the boundary includes non-loss and soil-loss conditions.Soil samples are filled into seven soil storerooms connected in turn.After evaluation,the variation in content of fine sand(ΔR_(f))and the hydraulic conductivity of soils in each storeroom(C_(i))are analyzed.In the non-loss test,the soil sample filling area is divided into runoff,transited,and accumulated areas according to the negative or positive ΔR_(f) values.ΔR_(f) increases from negative to positive along the seepage path,and Ci decreases from runoff area to transited area and then rebounds in accumulated area.In the soil-loss test,all soil sample filling areas belong to the runoff area,where the gentle-loss,strengthened-loss,and alleviated-loss parts are further divided.ΔR_(f) decreases from the gentle-loss part to the strengthened-loss part and then rebounds in the alleviated-loss part,and C_(i) increases and then decreases along the seepage path.The relationship between ΔR_(f) and Ci is different with the boundary condition.Ci exponentially decreases with ΔR_(f) in the non-loss test and increases with ΔR_(f) generally in the soil-loss test. 展开更多
关键词 Suffusion PERMEABILITY Experimental investigation Boundary effect Horizontal seepage
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Numerical investigation of friction-heating-pressurization and its control parameters in the shear band of high-speed landslides
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作者 ZHAO Nenghao CUI Shenghua LU Haijun 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3380-3395,共16页
High-speed sliding often leads to catastrophic landslides,many of which,in the initial sliding phase before disintegration,experience a friction-induced thermal pressurization effect in the bottom shear band,accelerat... High-speed sliding often leads to catastrophic landslides,many of which,in the initial sliding phase before disintegration,experience a friction-induced thermal pressurization effect in the bottom shear band,accelerating the movement of the overlying sliding mass.To quantitatively investigate this complex multiphysical phenomenon,we established a set of equations that describe the variations in temperature and excess pore pressure within the shear band,as well as the conservation of momentum equation for the overlying sliding mass.With a simplified landslide model,we investigated the variations of temperature and excess pore pressure within the shear band and their impacts on the velocity of the overlying sliding mass.On this basis,we studied the impact of seven key parameters on the maximum temperature and excess pore pressure in the shear band,as well as the impact on the velocity of the overlying sliding mass.The simulation results of the standard model show that the temperature and excess pore pressure in the shear band are significantly higher than those in the adjacent areas,and reach the maximum values in the center.Within a few seconds after the start,the maximum excess pore pressure in the shear zone is close to the initial stress,and the shear strength loss rate exceeds 90%.The thermal pressurization mechanism significantly increases the velocity of the overlying sliding mass.The results of parameter sensitivity analysis show that the thermal expansion coefficient has the most significant impact on the temperature and excess pore pressure in the shear band,and the sliding surface dip angle has the most significant impact on the velocity of the overlying sliding mass.The results of this study are of great significance for clarifying the mechanism of thermal pressurization-induced high-speed sliding. 展开更多
关键词 High-speed landslide Shear band Friction-heating-pressurization Numerical investigation
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Experimental investigation of dynamic characteristics of leaching tubing for solution mining of salt cavern carbon and energy storage
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作者 Yin-Ping Li Xin-Bo Ge +1 位作者 Xi-Lin Shi Hong-Ling Ma 《Petroleum Science》 SCIE EI CAS CSCD 2024年第4期2703-2722,共20页
Salt caverns are extensively utilized for storing various substances such as fossil energy,hydrogen,compressed air,nuclear waste,and industrial solid waste.In China,when the salt cavern is leached through single-well ... Salt caverns are extensively utilized for storing various substances such as fossil energy,hydrogen,compressed air,nuclear waste,and industrial solid waste.In China,when the salt cavern is leached through single-well water solution mining with oil as a cushion,engineering challenges arise with the leaching tubing,leading to issues like damage and instability.These problems significantly hinder the progress of cavern construction and the control of cavern shape.The primary cause of this is the flowinduced vibration instability of leaching tubing within a confined space,which results in severe bending or damage to the tubing.This study presents a model experimental investigation on the dynamic characteristics of leaching tubing using a self-developed liquid-solid coupling physical model experiment apparatus.The experiment utilizes a silicone-rubber pipe(SRP)and a polycarbonate pipe(PCP)to examine the effects of various factors on the dynamic stability of cantilevered pipes conveying fluid.These factors include external space constraint,flexural rigidity,medium outside the pipe,overhanging length,and end conditions.The experiments reveal four dynamic response phenomena:water hammer,static buckling,chaotic motion,and flutter instability.The study further demonstrates that the length of the external space constraint has a direct impact on the flutter critical flow velocity of the cantilevered pipe conveying fluid.Additionally,the flutter critical flow velocity is influenced by the end conditions and different external media. 展开更多
关键词 Salt cavern storage Solution mining Leaching tubing Experimental investigation Flutter instability
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Effect of trigger system on experimental dispersion characteristics of active surface wave testing
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作者 Lin Shibin Jeramy C.Ashlock +4 位作者 Zhu Liming Qin Zexiang Li Bo Zhu Xingji Zhai Changhai 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期311-318,共8页
A trigger system is typically employed in active seismic testing to trigger and synchronize multichannel surface wave data acquisition.The effect of the trigger system on the dispersion image of surface waves is empir... A trigger system is typically employed in active seismic testing to trigger and synchronize multichannel surface wave data acquisition.The effect of the trigger system on the dispersion image of surface waves is empirically known to be negligible,however,theoretical explanation regarding the effect of the trigger system is insufficient.This study systematically examines the theory for surface wave dispersion analysis and proves that the effect of the trigger system on a dispersion image is negligible via a solid theoretical explanation.Subsequently,based on the new theoretical explanation,an alternative method that uses only the relative phase difference between sensors to extract dispersion characteristics with better conceptual clarity is proposed.Two active surface wave testing cases are considered to validate the theory and method.The results indicate that(1)an accurate trigger system is not necessary for surface wave data acquisition,and(2)it is unnecessary to assume that the impact point is the generation point of the surface waves for the experimental dispersion analysis. 展开更多
关键词 site investigation surface waves data acquisition DISPERSION
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Serological Investigation into the Infected Genotypes of Patients with Japanese Encephalitis in the Coastal Provinces of China
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作者 Weijia Zhang Jierong Zhao +10 位作者 Qikai Yin Shenghui Liu Ruichen Wang Shihong Fu Fan Li Ying He Kai Nie Guodong Liang Songtao Xu Guang Yang Huanyu Wang 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第7期716-725,共10页
Objective Genotypes(G)1,3,and 5 of the Japanese encephalitis virus(JEV)have been isolated in China,but the dominant genotype circulating in Chinese coastal areas remains unknown.We searched for G5 JEV-infected cases a... Objective Genotypes(G)1,3,and 5 of the Japanese encephalitis virus(JEV)have been isolated in China,but the dominant genotype circulating in Chinese coastal areas remains unknown.We searched for G5 JEV-infected cases and attempted to elucidate which JEV genotype was most closely related to human Japanese encephalitis(JE)in the coastal provinces of China.Methods In this study,we collected serum specimens from patients with JE in three coastal provinces of China(Guangdong,Zhejiang,and Shandong)from 2018 to 2020 and conducted JEV cross-neutralization tests against G1,G3,and G5.Results Acute serum specimens from clinically reported JE cases were obtained for laboratory confirmation from hospitals in Shandong(92 patients),Zhejiang(192 patients),and Guangdong(77 patients),China,from 2018 to 2020.Seventy of the 361 serum specimens were laboratory-confirmed to be infected with JEV.Two cases were confirmed to be infected with G1 JEV,32 with G3 JEV,and two with G5 JEV.Conclusion G3 was the primary infection genotype among JE cases with a definite infection genotype,and the infection caused by G5 JEV was confirmed serologically in China. 展开更多
关键词 Japanese encephalitis virus Serological investigation Plaque reduction neutralization test Cross-neutralization test GENOTYPE
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"Win-Win"Scenario of High Energy Density and Long Cycling Life in a Novel Na_(3.9)MnCr_(0.9)Zr_(0.1)(PO_(4))_(3)Cathode
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作者 Yao Wang Yukun Liu +7 位作者 Pingge He Junteng Jin Xudong Zhao Qiuyu Shen Jie Li Xuanhui Qu Yongchang Liu Lifang Jiao 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第1期83-90,共8页
The development of high-energy and long-lifespan NASICON-type cathode materials for sodium-ion batteries has always been a research hotspot but a daunting challenge.Although Na_(4)MnCr(PO_(4))_(3)has emerged as one of... The development of high-energy and long-lifespan NASICON-type cathode materials for sodium-ion batteries has always been a research hotspot but a daunting challenge.Although Na_(4)MnCr(PO_(4))_(3)has emerged as one of the most promising high-energy-density cathode materials owing to its three-electron reactions,it still suffers from serious structural distortion upon repetitive charge/discharge processes caused by the Jahn-Teller active Mn^(3+).Herein,the selective substitution of Cr by Zr in Na_(4)MnCr(PO_(4))_(3)was explored to enhance the structural stability,due to the pinning effect of Zr ions and the≈2.9-electron reactions,as-prepared Na_(3.9)MnCr_(0.9)Zr_(0.1)(PO_(4))_(3)/C delivers a high capacity retention of 85.94%over 500 cycles at 5 C and an ultrahigh capacity of 156.4 mAh g^(-1)at 0.1 C,enabling the stable energy output as high as 555.2 Wh kg^(-1).Moreover,during the whole charge/discharge process,a small volume change of only 6.7%was verified by in situ X-ray diffraction,and the reversible reactions of Cr^(3+)/Cr^(4+),Mn^(3+)/Mn^(4+),and Mn^(2+)/Mn^(3+)redox couples were identified via ex situ X-ray photoelectron spectroscopy analyses.Galvanostatic intermittent titration technique tests and density functional theory calculations further demonstrated the fast reaction kinetics of the Na_(3.9)MnCr_(0.9)Zr_(0.1)(PO_(4))_(3)/C electrode.This work offers new opportunities for designing high-energy and high-stability NASICON cathodes by ion doping. 展开更多
关键词 high energy density mechanism investigation NASICON-type cathodes sodium-ion batteries structure modification
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Finite Element Simulation Analysis of a Novel 3D-FRSPA for Crawling Locomotion
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作者 Bingzhu Wang Xiangrui Ye 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1401-1425,共25页
A novel three-dimensional-fiber reinforced soft pneumatic actuator(3D-FRSPA)inspired by crab claw and human hand structure that can bend and deform independently in each segment is proposed.It has an omni-directional ... A novel three-dimensional-fiber reinforced soft pneumatic actuator(3D-FRSPA)inspired by crab claw and human hand structure that can bend and deform independently in each segment is proposed.It has an omni-directional bending configuration,and the fibers twined symmetrically on both sides to improve the bending performance of FRSPA.In this paper,the static and kinematic analysis of 3D-FRSPA are carried out in detail.The effects of fiber,pneumatic chamber and segment length,and circular air chamber radius of 3D-FRSPA on the mechanical performance of the actuator are discussed,respectively.The soft mobile robot composed of 3D-FRSPA has the ability to crawl.Finally,the crawling processes of the soft mobile robot on different road conditions are studied,respectively,and the motion mechanism of the mobile actuator is shown.The numerical results show that the soft mobile robots have a good comprehensive performance,which verifies the correctness of the proposedmodel.This work shows that the proposed structures have great potential in complex road conditions,unknown space detection and other operations. 展开更多
关键词 3D-FRSPA bionic structure theoretical modeling crawling application obstacle avoidance analysis numerical investigation
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Auto-parametric resonance of a continuous-beam-bridge model under two-point periodic excitation:an experimental investigation and stability analysis
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作者 Li Yuchun Shen Chao +1 位作者 Liu Wei Li Dong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期445-454,共10页
The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the ... The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the test model is conducted to observe and measure the auto-parametric resonance of a continuous beam under a two-point excitation on columns.The parametric vibration equation is established for the test model using the finite-element method.The auto-parametric resonance stability of the structure is analyzed by using Newmark's method and the energy-growth exponent method.The effects of the phase difference of the two-point excitation on the stability boundaries of auto-parametric resonance are studied for the test model.Compared with the experiment,the numerical instability predictions of auto-parametric resonance are consistent with the test phenomena,and the numerical stability boundaries of auto-parametric resonance agree with the experimental ones.For a continuous beam bridge,when the ratio of multipoint excitation frequency(applied to the columns)to natural frequency of the continuous girder is approximately equal to 2,the continuous beam may undergo a strong auto-parametric resonance.Combined with the present experiment and analysis,a hypothesis of Volgograd Bridge's serpentine vibration is discussed. 展开更多
关键词 auto-parametric resonance continuous beam bridge model two-point excitation experimental investigation stability analysis vibration of Volgograd Bridge
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Comparative study of different machine learning models in landslide susceptibility assessment: A case study of Conghua District, Guangzhou, China
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作者 Ao Zhang Xin-wen Zhao +8 位作者 Xing-yuezi Zhao Xiao-zhan Zheng Min Zeng Xuan Huang Pan Wu Tuo Jiang Shi-chang Wang Jun He Yi-yong Li 《China Geology》 CAS CSCD 2024年第1期104-115,共12页
Machine learning is currently one of the research hotspots in the field of landslide prediction.To clarify and evaluate the differences in characteristics and prediction effects of different machine learning models,Co... Machine learning is currently one of the research hotspots in the field of landslide prediction.To clarify and evaluate the differences in characteristics and prediction effects of different machine learning models,Conghua District,which is the most prone to landslide disasters in Guangzhou,was selected for landslide susceptibility evaluation.The evaluation factors were selected by using correlation analysis and variance expansion factor method.Applying four machine learning methods namely Logistic Regression(LR),Random Forest(RF),Support Vector Machines(SVM),and Extreme Gradient Boosting(XGB),landslide models were constructed.Comparative analysis and evaluation of the model were conducted through statistical indices and receiver operating characteristic(ROC)curves.The results showed that LR,RF,SVM,and XGB models have good predictive performance for landslide susceptibility,with the area under curve(AUC)values of 0.752,0.965,0.996,and 0.998,respectively.XGB model had the highest predictive ability,followed by RF model,SVM model,and LR model.The frequency ratio(FR)accuracy of LR,RF,SVM,and XGB models was 0.775,0.842,0.759,and 0.822,respectively.RF and XGB models were superior to LR and SVM models,indicating that the integrated algorithm has better predictive ability than a single classification algorithm in regional landslide classification problems. 展开更多
关键词 Landslides susceptibility assessment Machine learning Logistic Regression Random Forest Support Vector Machines XGBoost Assessment model Geological disaster investigation and prevention engineering
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Systematic investigation of Radix Salviae for treating diabetic peripheral neuropathy disease based on network Pharmacology
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作者 Tao Kang Xiao Qin +1 位作者 Yan Chen Qian Yang 《World Journal of Diabetes》 SCIE 2024年第5期945-957,共13页
BACKGROUND Diabetic peripheral neuropathy(DPN)is a debilitating complication of diabetes mellitus with limited available treatment options.Radix Salviae,a traditional Chinese herb,has shown promise in treating DPN,but... BACKGROUND Diabetic peripheral neuropathy(DPN)is a debilitating complication of diabetes mellitus with limited available treatment options.Radix Salviae,a traditional Chinese herb,has shown promise in treating DPN,but its therapeutic mech-anisms have not been systematically investigated.AIM Radix Salviae(Danshen in pinin),a traditional Chinese medicine(TCM),is widely used to treat DPN in China.However,the mechanism through which Radix Salviae treats DPN remains unclear.Therefore,we aimed to explore the mechanism of action of Radix Salviae against DPN using network pharmacology.METHODS The active ingredients and target genes of Radix Salviae were screened using the TCM pharmacology database and analysis platform.The genes associated with DPN were obtained from the Gene Cards and OMIM databases,a drug-com-position-target-disease network was constructed,and a protein–protein inter-action network was subsequently constructed to screen the main targets.Gene Ontology(GO)functional annotation and pathway enrichment analysis were performed via the Kyoto Encyclopedia of Genes and Genomes(KEGG)using Bioconductor.RESULTS A total of 56 effective components,108 targets and 4581 DPN-related target genes of Radix Salviae were screened.Intervention with Radix Salviae for DPN mainly involved 81 target genes.The top 30 major targets were selected for enrichment analysis of GO and KEGG pathways.CONCLUSION These results suggested that Radix Salviae could treat DPN by regulating the AGE-RAGE signaling pathway and the PI3K-Akt signaling pathway.Therefore,Danshen may affect DPN by regulating inflammation and apoptosis. 展开更多
关键词 Diabetic peripheral neuropathy Radix Salviae Network pharmacology Systematic investigation
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A Survey of Crime Scene Investigation Image Retrieval Using Deep Learning
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作者 Ying Liu Aodong Zhou +1 位作者 Jize Xue Zhijie Xu 《Journal of Beijing Institute of Technology》 EI CAS 2024年第4期271-286,共16页
Crime scene investigation(CSI)image is key evidence carrier during criminal investiga-tion,in which CSI image retrieval can assist the public police to obtain criminal clues.Moreover,with the rapid development of deep... Crime scene investigation(CSI)image is key evidence carrier during criminal investiga-tion,in which CSI image retrieval can assist the public police to obtain criminal clues.Moreover,with the rapid development of deep learning,data-driven paradigm has become the mainstreammethod of CSI image feature extraction and representation,and in this process,datasets provideeffective support for CSI retrieval performance.However,there is a lack of systematic research onCSI image retrieval methods and datasets.Therefore,we present an overview of the existing worksabout one-class and multi-class CSI image retrieval based on deep learning.According to theresearch,based on their technical functionalities and implementation methods,CSI image retrievalis roughly classified into five categories:feature representation,metric learning,generative adversar-ial networks,autoencoder networks and attention networks.Furthermore,We analyzed the remain-ing challenges and discussed future work directions in this field. 展开更多
关键词 crime scene investigation(CSI)image image retrieval deep learning
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