BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary art...BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.展开更多
Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass...Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.展开更多
The study makes a contrastive analysis of the differences in the comments of people from different social status in their Mini-blogs.It aims to find the manifestations of those differences by analyzing the underlying ...The study makes a contrastive analysis of the differences in the comments of people from different social status in their Mini-blogs.It aims to find the manifestations of those differences by analyzing the underlying causes and provide constructive suggestions on how to build a more harmonious public platform,which is of its great significance.展开更多
With the rising and spreading of micro-blog, the sentiment classification of short texts has become a research hotspot. Some methods have been developed in the past decade. However, since the Chinese and English are d...With the rising and spreading of micro-blog, the sentiment classification of short texts has become a research hotspot. Some methods have been developed in the past decade. However, since the Chinese and English are different in language syntax, semantics and pragmatics, sentiment classification methods that are effective for English twitter may fail on Chinese micro-blog. In addition, the colloquialism and conciseness of short Chinese texts introduces additional challenges to sentiment classification. In this work, a novel hybrid learning model was proposed for sentiment classification of Chinese micro-blogs, which included two stages. In the first stage, emotional scores were calculated over the whole dataset by utilizing an improved Chinese-oriented sentiment dictionary classification method. Data with extremely high or low scores were directly labeled. In the second stage, the remaining data were labeled by using an integrated classification method based on sentiment dictionary, support vector machine(SVM) and k-nearest neighbor(KNN). An improved feature selection method was adopted to enhance the discriminative power of the selected features. The two-stage hybrid framework made the proposed method effective for sentiment classification of Chinese micro-blogs. Experiments on the COAE2014(Chinese Opinion Analysis Evaluation 2014) dataset show that the proposed method outperforms other schemes.展开更多
In this work, a rumor’s spreading and controlling in a directed Micro-blog user network being consisted with 580 000 nodes are simulated. By defining some authority nodes that release anti-rumor information as the pr...In this work, a rumor’s spreading and controlling in a directed Micro-blog user network being consisted with 580 000 nodes are simulated. By defining some authority nodes that release anti-rumor information as the prevention strategy, the effect of the nodes’ role in network on rumor’s suppression is studied. The findings show that rumor will be spread out fast and reach a stable level within limited steps. The suppression of rumor is more predominated by the intervening opportunity, the earlier the intervention strategy was implemented, the better the rumor’s controlling could be achieved. The controlling effect is less relevant with the role of the authority nodes in network.展开更多
After the occurrence of unexpected group events of network, the relevant opinion information will spread rapidly through micro-blog, and the negative public opinion information will aggravate the unexpected the group ...After the occurrence of unexpected group events of network, the relevant opinion information will spread rapidly through micro-blog, and the negative public opinion information will aggravate the unexpected the group events to upgrade and expand the scope of harm. It is difficult to deal. So public opinion control is very important. In this paper, we establish an influence model for spreading of public opinion based on SIR model. Through the political analysis, this paper finds that the network group events will subside, but the influence scope, time and ability of event cannot be ignored. As a result of this study, the corresponding strategies are put forward in this paper.展开更多
User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influenc...User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influence on the information multi-step communication in a micro-biog. The multi-steps of information communication are divided into first-step and non-first-step, and user influence is classified into five dimensions. Actual data from the Sina micro-blog is collected to construct the model by means of an approach based on structural equations that uses the Partial Least Squares （PLS） technique. Our experimental results indicate that the dimensions of the number of fans and their authority significantly impact the information of first-step conxrnunication. Leader rank has a positive impact on both first-step and non-first-step communication. Moreover, global centrality and weight of friends are positively related to the information non-first-step communication, but authority is found to have much less relation to it.展开更多
Taking Meteorological Knowledge official micro-blog ＂ Meteorological Knowledge＂ and Beijing Meteorological Bureau official micro-blog ＂ Meteorology Beijing＂ as the research objects,the differences of different typ...Taking Meteorological Knowledge official micro-blog ＂ Meteorological Knowledge＂ and Beijing Meteorological Bureau official micro-blog ＂ Meteorology Beijing＂ as the research objects,the differences of different types of meteorological government micro-blog and the contribution of each factor were analyzed by comparing changes of the number of fans,micro-blog comments and forwarding and other key elements during March1 to May 31 in 2012. The results showed that the number of fans was one of important indexes to determine the influence of meteorological government micro-blog,and the high active fans played a more prominent role. During the period of study,the fans number of ＂ Meteorology Beijing＂ was far more than ＂ Meteorological Knowledge＂,the daily micro-blog released number and comment forwarding number were both more than ＂ Meteorological knowledge＂,but the proportion of active fans of ＂ Meteorological knowledge＂ was larger than ＂ Meteorology Beijing＂. Timeliness was of greater contribution to advancing the meteorological government micro-blog influence. During the period of study,the proportions of comments and forwarding number of morning weather forecast were the largest,the evening weather forecast took the second place,and the noon was the smallest.But the influence of noon weather forecast micro-blog increased most highly approximately by 15% because of the higher timeliness. The content and form also made great contribution to the influence of meteorological government micro-blog. Comparison of different types of meteorological micro-blog showed that,the number of fans and the influence of meteorological government micro-blog which mainly published real-time meteorological information were larger than which mainly published meteorological popular science knowledge.展开更多
Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly re...Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly rely on traditional bottom-up method,which involves tedious steps,time-consuming treatments,or additional alkaline media,and is unfavorable for high-efficiency production.Herein,we present a facile,ultrafast and general avenue to synthesize transition metal hydroxides on carbon substrate within 13 s by Joule-heating method.With high reaction kinetics caused by the instantaneous high temperature,seven kinds of transition metal-layered hydroxides(TM-LDHs)are formed on carbon cloth.Therein,the fastest synthesis rate reaches~0.46 cm^(2)s^(-1).Density functional theory calculations further demonstrate the nucleation energy barriers and potential mechanism for the formation of metal-based hydroxides on carbon substrates.This efficient approach avoids the use of extra agents,multiple steps,and long production time and endows the LDHs@carbon cloth with outstanding flexibility and machinability,showing practical advantages in both common and micro-zinc ion-based energy storage devices.To prove its utility,as a cathode in rechargeable aqueous alkaline Zn(micro-)battery,the NiCo LDH@carbon cloth exhibits a high energy density,superior to most transition metal LDH materials reported so far.展开更多
By conducting experimental analyses, including thermal pyrolysis, micro-/nano-CT, argon-ion polishing field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and two-dimensiona...By conducting experimental analyses, including thermal pyrolysis, micro-/nano-CT, argon-ion polishing field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and two-dimensional nuclear magnetic resonance (2D NMR), the Gulong shale oil in the Songliao Basin was investigated with respect to formation model, pore structure and accumulation mechanism. First, in the Gulong shale, there are a large number of pico-algae, nano-algae and dinoflagellates, which were formed in brackish water environment and constituted the hydrogen-rich oil source materials of shale. Second, most of the oil-generating materials of the Qingshankou Formation shale exist in the form of organo-clay complex. During organic matter thermal evolution, clay minerals had double effects of suppression and catalytic hydrogenation, which expanded shale oil window and increased light hydrocarbon yield. Third, the formation of storage space in the Gulong Shale was related to dissolution and hydrocarbon generation. With the diagenesis, micro-/nano-pores increased, pore diameter decreased and more bedding fractures appeared, which jointly gave rise to the unique reservoir with dual media (i.e. nano-scale pores and micro-scale bedding fractures) in the Gulong shale. Fourth, the micro-/nano-scale oil storage unit in the Gulong shale exhibits independent oil/gas occurrence phase, and shows that all-size pores contain oils, which occur in condensate state in micropores or in oil-gas two phase (or liquid) state in macropores/mesopores. The understanding about Gulong shale oil formation and accumulation mechanism has theoretical and practical significance for advancing continental shale oil exploration in China.展开更多
基金the 305 Hospital Independent Scientific Research Fund,2024,No.24ZZJJLW-022.
文摘BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.
文摘Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.
文摘The study makes a contrastive analysis of the differences in the comments of people from different social status in their Mini-blogs.It aims to find the manifestations of those differences by analyzing the underlying causes and provide constructive suggestions on how to build a more harmonious public platform,which is of its great significance.
基金Projects(61573380,61303185)supported by the National Natural Science Foundation of ChinaProject(13BTQ052)supported by the National Social Science Foundation of China+1 种基金Project(2016M592450)supported by the China Postdoctoral Science FoundationProject(2016JJ4119)supported by the Hunan Provincial Natural Science Foundation of China
文摘With the rising and spreading of micro-blog, the sentiment classification of short texts has become a research hotspot. Some methods have been developed in the past decade. However, since the Chinese and English are different in language syntax, semantics and pragmatics, sentiment classification methods that are effective for English twitter may fail on Chinese micro-blog. In addition, the colloquialism and conciseness of short Chinese texts introduces additional challenges to sentiment classification. In this work, a novel hybrid learning model was proposed for sentiment classification of Chinese micro-blogs, which included two stages. In the first stage, emotional scores were calculated over the whole dataset by utilizing an improved Chinese-oriented sentiment dictionary classification method. Data with extremely high or low scores were directly labeled. In the second stage, the remaining data were labeled by using an integrated classification method based on sentiment dictionary, support vector machine(SVM) and k-nearest neighbor(KNN). An improved feature selection method was adopted to enhance the discriminative power of the selected features. The two-stage hybrid framework made the proposed method effective for sentiment classification of Chinese micro-blogs. Experiments on the COAE2014(Chinese Opinion Analysis Evaluation 2014) dataset show that the proposed method outperforms other schemes.
文摘In this work, a rumor’s spreading and controlling in a directed Micro-blog user network being consisted with 580 000 nodes are simulated. By defining some authority nodes that release anti-rumor information as the prevention strategy, the effect of the nodes’ role in network on rumor’s suppression is studied. The findings show that rumor will be spread out fast and reach a stable level within limited steps. The suppression of rumor is more predominated by the intervening opportunity, the earlier the intervention strategy was implemented, the better the rumor’s controlling could be achieved. The controlling effect is less relevant with the role of the authority nodes in network.
文摘After the occurrence of unexpected group events of network, the relevant opinion information will spread rapidly through micro-blog, and the negative public opinion information will aggravate the unexpected the group events to upgrade and expand the scope of harm. It is difficult to deal. So public opinion control is very important. In this paper, we establish an influence model for spreading of public opinion based on SIR model. Through the political analysis, this paper finds that the network group events will subside, but the influence scope, time and ability of event cannot be ignored. As a result of this study, the corresponding strategies are put forward in this paper.
基金supported by the National Natural Science Foundation of China(Grant No.60873246)China Information Technology Security Evaluation Center
文摘User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influence on the information multi-step communication in a micro-biog. The multi-steps of information communication are divided into first-step and non-first-step, and user influence is classified into five dimensions. Actual data from the Sina micro-blog is collected to construct the model by means of an approach based on structural equations that uses the Partial Least Squares （PLS） technique. Our experimental results indicate that the dimensions of the number of fans and their authority significantly impact the information of first-step conxrnunication. Leader rank has a positive impact on both first-step and non-first-step communication. Moreover, global centrality and weight of friends are positively related to the information non-first-step communication, but authority is found to have much less relation to it.
基金Supported by the Public Industry(Meteorology) Special Funds for Scientific Research Projects(GYHY201106037)
文摘Taking Meteorological Knowledge official micro-blog ＂ Meteorological Knowledge＂ and Beijing Meteorological Bureau official micro-blog ＂ Meteorology Beijing＂ as the research objects,the differences of different types of meteorological government micro-blog and the contribution of each factor were analyzed by comparing changes of the number of fans,micro-blog comments and forwarding and other key elements during March1 to May 31 in 2012. The results showed that the number of fans was one of important indexes to determine the influence of meteorological government micro-blog,and the high active fans played a more prominent role. During the period of study,the fans number of ＂ Meteorology Beijing＂ was far more than ＂ Meteorological Knowledge＂,the daily micro-blog released number and comment forwarding number were both more than ＂ Meteorological knowledge＂,but the proportion of active fans of ＂ Meteorological knowledge＂ was larger than ＂ Meteorology Beijing＂. Timeliness was of greater contribution to advancing the meteorological government micro-blog influence. During the period of study,the proportions of comments and forwarding number of morning weather forecast were the largest,the evening weather forecast took the second place,and the noon was the smallest.But the influence of noon weather forecast micro-blog increased most highly approximately by 15% because of the higher timeliness. The content and form also made great contribution to the influence of meteorological government micro-blog. Comparison of different types of meteorological micro-blog showed that,the number of fans and the influence of meteorological government micro-blog which mainly published real-time meteorological information were larger than which mainly published meteorological popular science knowledge.
基金the NSFC(22075019)National Key R&D Program of China(2017YFB1104300)。
文摘Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly rely on traditional bottom-up method,which involves tedious steps,time-consuming treatments,or additional alkaline media,and is unfavorable for high-efficiency production.Herein,we present a facile,ultrafast and general avenue to synthesize transition metal hydroxides on carbon substrate within 13 s by Joule-heating method.With high reaction kinetics caused by the instantaneous high temperature,seven kinds of transition metal-layered hydroxides(TM-LDHs)are formed on carbon cloth.Therein,the fastest synthesis rate reaches~0.46 cm^(2)s^(-1).Density functional theory calculations further demonstrate the nucleation energy barriers and potential mechanism for the formation of metal-based hydroxides on carbon substrates.This efficient approach avoids the use of extra agents,multiple steps,and long production time and endows the LDHs@carbon cloth with outstanding flexibility and machinability,showing practical advantages in both common and micro-zinc ion-based energy storage devices.To prove its utility,as a cathode in rechargeable aqueous alkaline Zn(micro-)battery,the NiCo LDH@carbon cloth exhibits a high energy density,superior to most transition metal LDH materials reported so far.
基金Supported by the Central Guiding Local Science and Technology Development Special Project(ZY20B13)。
文摘By conducting experimental analyses, including thermal pyrolysis, micro-/nano-CT, argon-ion polishing field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and two-dimensional nuclear magnetic resonance (2D NMR), the Gulong shale oil in the Songliao Basin was investigated with respect to formation model, pore structure and accumulation mechanism. First, in the Gulong shale, there are a large number of pico-algae, nano-algae and dinoflagellates, which were formed in brackish water environment and constituted the hydrogen-rich oil source materials of shale. Second, most of the oil-generating materials of the Qingshankou Formation shale exist in the form of organo-clay complex. During organic matter thermal evolution, clay minerals had double effects of suppression and catalytic hydrogenation, which expanded shale oil window and increased light hydrocarbon yield. Third, the formation of storage space in the Gulong Shale was related to dissolution and hydrocarbon generation. With the diagenesis, micro-/nano-pores increased, pore diameter decreased and more bedding fractures appeared, which jointly gave rise to the unique reservoir with dual media (i.e. nano-scale pores and micro-scale bedding fractures) in the Gulong shale. Fourth, the micro-/nano-scale oil storage unit in the Gulong shale exhibits independent oil/gas occurrence phase, and shows that all-size pores contain oils, which occur in condensate state in micropores or in oil-gas two phase (or liquid) state in macropores/mesopores. The understanding about Gulong shale oil formation and accumulation mechanism has theoretical and practical significance for advancing continental shale oil exploration in China.
