The stress and the strain should be defined as statistical variables averaged over the representative volume elements for any real continuum system.It is shown that their nonlinear spatial distributions undermine the ...The stress and the strain should be defined as statistical variables averaged over the representative volume elements for any real continuum system.It is shown that their nonlinear spatial distributions undermine the classical framework of solid mechanics and may cause non-ignorable errors to the solutions.With considering the high-order gradients of the stress and the strain,a two-step solution scheme is proposed to compensate for the influence.Through a revisit to three simple but typical problems,i.e.,the hole size-dependence of the fracture strength of perforated plates,the indentation depth-dependence of the measured elastic modulus by micro-indentation tests,and the tensile necking of metallic materials as well as hyperelastic materials,the effect of the nonlinear spatial distribution of stress and strain on solving these problems is illustrated.The observed size effect and the instability of deformation can be quantitatively explained if the effect is properly considered by the proposed method.展开更多
Precisely quantifying the strength of the proximal femur and accurately assessing hip fracture risk would enable those at high risk to be identified so that preventive interventions could be taken.Development of bette...Precisely quantifying the strength of the proximal femur and accurately assessing hip fracture risk would enable those at high risk to be identified so that preventive interventions could be taken.Development of better measures of femoral strength using the clinically展开更多
Objective:To explore the effects of daily mean temperature(°C),average daily air pressure(hPa),humidity(%),wind speed(m/s),particulate matter(PM)2.5(μg/m3)and PM10(μg/m3)on the admission rate of chronic kidney ...Objective:To explore the effects of daily mean temperature(°C),average daily air pressure(hPa),humidity(%),wind speed(m/s),particulate matter(PM)2.5(μg/m3)and PM10(μg/m3)on the admission rate of chronic kidney disease(CKD)patients admitted to the Second Affiliated Hospital of Harbin Medical University in Harbin and to identify the indexes and lag days that impose the most critical influence.Methods:The R language Distributed Lag Nonlinear Model(DLNM),Excel,and SPSS were used to analyze the disease and meteorological data of Harbin from 01 January 2010 to 31 December 2019 according to the inclusion and exclusion criteria.Results:Meteorological factors and air pollution influence the number of hospitalizations of CKD to vary degrees in cold regions,and differ in persistence or delay.Non-optimal temperature increases the risk of admission of CKD,high temperature increases the risk of obstructive kidney disease,and low temperature increases the risk of other major types of chronic kidney disease.The greater the temperature difference is,the higher its contribution is to the risk.The non-optimal wind speed and non-optimal atmospheric pressure are associated with increased hospital admissions.PM2.5 concentrations above 40μg/m3 have a negative impact on the results.Conclusion:Cold region meteorology and specific environment do have an impact on the number of hospital admissions for chronic kidney disease,and we can apply DLMN to describe the analysis.展开更多
Objective:To assess the correlation between atmospheric pollutants,meteorological factors,and emergency department visits for respiratory diseases in Haikou City.Methods:Daily data on atmospheric pollutants,meteorolog...Objective:To assess the correlation between atmospheric pollutants,meteorological factors,and emergency department visits for respiratory diseases in Haikou City.Methods:Daily data on atmospheric pollutants,meteorological factors,and emergency department visits for respiratory diseases in Haikou City from 2018 to 2021 were collected.The Spearman rank correlation test was used to analyze the correlation,and a distributed lag non-linear model was employed to analyze the health effects and lag impacts of environmental factors.Subgroup analyses were conducted based on sex and age.Results:According to the criteria of International Classification of Diseases(ICD-10:J00-J99),a total of 221913 cases were included,accounting for 21.3%of the total emergency department visits in Haikou City.For every 1℃increase in temperature,the risk of emergency department visits increased by 1.029%(95%CI 1.016%-1.042%).Relative humidity greater than 80%reduced the risk of visits,while higher atmospheric pressure(>1010 hpa)also decreased the likelihood of daily emergency department visits.Higher concentrations of PM_(2.5)(30-50μg/m^(3)),PM10(>60μg/m^(3)),and O_(3)(75-125μg/m^(3))were associated with increased visits.Higher temperatures(>25℃)have a greater impact on females and children aged 0-14 years,while males are more sensitive to low atmospheric pressure.Individuals aged 65 and above exhibited increased sensitivity to O_(3)concentration,and the effects of PM2.5,PM10,and O_(3)are more pronounced in individuals over 14 years old.Conclusions:Short-term exposure to high temperatures,particulate matter pollutants(PM_(2.5)and PM_(10)),and ozone(O_(3))is associated with increased emergency department visits for respiratory diseases.展开更多
The sensitivity of collinear nonlinear nondestructive testing technique based on harmonic detection is high,but the results are vulnerable to interference from other nonlinear of experiment sources,which leads to this...The sensitivity of collinear nonlinear nondestructive testing technique based on harmonic detection is high,but the results are vulnerable to interference from other nonlinear of experiment sources,which leads to this technology limited in industrial applications.To solve this problem,a non-collinear nonlinear ultrasonic testing experimental system is established based on non-collinear beam mixing technology.The non-collinear nonlinear response is observed in the steel and LY12 aluminum alloy.The results show that:1 Based on the benefits of space selection,mode conversion,frequency and steerable optional of non-collinear beam mixing technology,the interference of system nonlinear effects can be suppressed effectively;2 Mode conversion and beam mixing are present in steel and LY12 aluminum alloy,and the non-collinear non-linear response of LY12 aluminum alloy is stronger than steel and the measurement results are more obvious;3 The technology has the feasibility to evaluate the uniformity of material internal.展开更多
The nonlinear dynamics of cantilevered piezoelectric beams is investigated under simultaneous parametric and external excitations. The beam is composed of a substrate and two piezoelectric layers and assumed as an Eul...The nonlinear dynamics of cantilevered piezoelectric beams is investigated under simultaneous parametric and external excitations. The beam is composed of a substrate and two piezoelectric layers and assumed as an Euler-Bernoulli model with inextensible deformation. A nonlinear distributed parameter model of cantilevered piezoelectric energy harvesters is proposed using the generalized Hamilton's principle. The proposed model includes geometric and inertia nonlinearity, but neglects the material nonlinearity. Using the Galerkin decomposition method and harmonic balance method, analytical expressions of the frequency-response curves are presented when the first bending mode of the beam plays a dominant role. Using these expressions, we investigate the effects of the damping, load resistance, electromechanical coupling, and excitation amplitude on the frequency-response curves. We also study the difference between the nonlinear lumped-parameter and distributed- parameter model for predicting the performance of the energy harvesting system. Only in the case of parametric excitation, we demonstrate that the energy harvesting system has an initiation excitation threshold below which no energy can be harvested. We also illustrate that the damping and load resistance affect the initiation excitation threshold.展开更多
Objective This study aimed to determine the spatiotemporal distribution and epidemiological characteristics of hospital admissions for carbon monoxide poisoning(COP)in Guangdong,China,from 2013 to 2020.Methods Data on...Objective This study aimed to determine the spatiotemporal distribution and epidemiological characteristics of hospital admissions for carbon monoxide poisoning(COP)in Guangdong,China,from 2013 to 2020.Methods Data on age-and sex-specific numbers of hospital admissions due to COP in Guangdong(2013-2020)were collected.Daily temperatures were downloaded through the China Meteorological Data Sharing Service System.We analyzed temporal trends through time series decomposition and used spatial autocorrelation analysis to detect spatial clustering.The distributed lag nonlinear model was used to quantify the effects of temperature.Results There were 48,854 COP admissions over the study period.The sex ratio(male to female)was1:1.74.The concentration ratios(M)ranged from 0.73-0.82.The highest risk occurred in January(season index=3.59).Most cases were concentrated in the northern mountainous areas of Guangdong with high-high clustering.COP in the study region showed significant spatial autocorrelation,and the global Moran’s I value of average annual hospital admission rates for COP was 0.447(P<0.05).Low temperatures were associated with high hospital admission rates for COP,with a lag lasting 7 days.With a lag of 0 days,the effects of low temperatures[5th(12℃)]on COP were 2.24-3.81,as compared with the reference temperature[median(24℃)].Conclusion COP in Guangdong province showed significant temporal and spatial heterogeneity.Low temperature was associated with a high risk of COP,and the influence had a lag lasting 7 days.展开更多
We find an upper viscosity solution and give a proof of the existence-uniqueness in the space C^∞(t∈(0,∞);H2^s+2(R^n))∩C^0(t∈[0,∞);H^s(R^n)),s∈R,to the nonlinear time fractional equation of distribu...We find an upper viscosity solution and give a proof of the existence-uniqueness in the space C^∞(t∈(0,∞);H2^s+2(R^n))∩C^0(t∈[0,∞);H^s(R^n)),s∈R,to the nonlinear time fractional equation of distributed order with spatial Laplace operator subject to the Cauchy conditions ∫0^2p(β)D*^βu(x,t)dβ=△xu(x,t)+f(t,u(t,x)),t≥0,x∈R^n,u(0,x)=φ(x),ut(0,x)=ψ(x),(0.1) where △xis the spatial Laplace operator,D*^β is the operator of fractional differentiation in the Caputo sense and the force term F satisfies the Assumption 1 on the regularity and growth. For the weight function we take a positive-linear combination of delta distributions concentrated at points of interval (0, 2), i.e., p(β) =m∑k=1bkδ(β-βk),0〈βk〈2,bk〉0,k=1,2,…,m.The regularity of the solution is established in the framework of the space C^∞(t∈(0,∞);C^∞(R^n))∩C^0(t∈[0,∞);C^∞(R^n))when the initial data belong to the Sobolev space H2^8(R^n),s∈R.展开更多
Statistical analysis was done on simultaneous wave and wind using data recorded by discus-shape wave buoy. The area is located in the southern Caspian Sea near the Anzali Port. Recorded wave data were obtained through...Statistical analysis was done on simultaneous wave and wind using data recorded by discus-shape wave buoy. The area is located in the southern Caspian Sea near the Anzali Port. Recorded wave data were obtained through directional spectrum wave analysis. Recorded wind direction and wind speed were obtained through the related time series as well. For 12-month measurements(May 25 2007-2008), statistical calculations were done to specify the value of nonlinear auto-correlation of wave and wind using the probability distribution function of wave characteristics and statistical analysis in various time periods. The paper also presents and analyzes the amount of wave energy for the area mentioned on the basis of available database. Analyses showed a suitable comparison between the amounts of wave energy in different seasons. As a result, the best period for the largest amount of wave energy was known. Results showed that in the research period, the mean wave and wind auto correlation were about three hours. Among the probability distribution functions, i.e Weibull, Normal, Lognormal and Rayleigh, "Weibull" had the best consistency with experimental distribution function shown in different diagrams for each season. Results also showed that the mean wave energy in the research period was about 49.88 k W/m and the maximum density of wave energy was found in February and March, 2010.展开更多
Background Tuberculosis(TB)remains a pressing public health issue,posing a significant threat to individuals'well-being and lives.This study delves into the TB incidence in Chinese mainland during 2014-2021,aiming...Background Tuberculosis(TB)remains a pressing public health issue,posing a significant threat to individuals'well-being and lives.This study delves into the TB incidence in Chinese mainland during 2014-2021,aiming to gain deeper insights into their epidemiological characteristics and explore macro-level factors to enhance control and prevention.Methods TB incidence data in Chinese mainland from 2014 to 2021 were sourced from the National Notifiable Disease Reporting System(NNDRS).A two-stage distributed lag nonlinear model(DLNM)was constructed to evaluate the lag and non-linearity of daily average temperature(℃,Atemp),average relative humidity(%,ARH),average wind speed(m/s,AWS),sunshine duration(h,SD)and precipitation(mm,PRE)on the TB incidence.A spatial panel data model was used to assess the impact of demographic,medical and health resource,and economic factors on TB incidence.Results A total of 6,587,439 TB cases were reported in Chinese mainland during 2014-2021,with an average annual incidence rate of 59.17/100,000.The TB incidence decreased from 67.05/100,000 in 2014 to 46.40/100,000 in 2021,notably declining from 2018 to 2021(APC=-8.87%,95%CI:-11.97,-6.85%).TB incidence rates were higher among males,farmers,and individuals aged 65 years and older.Spatiotemporal analysis revealed a significant cluster in Xinjiang,Qinghai,and Xizang from March 2017 to June 2019(RR=3.94,P<0.001).From 2014 to 2021,the proportion of etiologically confirmed cases increased from 31.31%to 56.98%,and the time interval from TB onset to diagnosis shortened from 26 days(IQR:10-56 days)to 19 days(IQR:7-44 days).Specific meteorological conditions,including low temperature(<16.69℃),high relative humidity(>71.73%),low sunshine duration(<6.18 h)increased the risk of TB incidence,while extreme low wind speed(<2.79 m/s)decreased the risk.The spatial Durbin model showed positive associations between TB incidence rates and sex ratio(β=1.98),number of beds in medical and health institutions per 10,000 population(β=0.90),and total health expenses(β=0.55).There were negative associations between TB incidence rates and population(β=-1.14),population density(β=-0.19),urbanization rate(β=-0.62),number of medical and health institutions(β=-0.23),and number of health technicians per 10,000 population(β=-0.70).Conclusions Significant progress has been made in TB control and prevention in China,but challenges persist among some populations and areas.Varied relationships were observed between TB incidence and factors from meteorological,demographic,medical and health resource,and economic aspects.These findings underscore the importance of ongoing efforts to strengthen TB control and implement digital/intelligent surveillance for early risk detection and comprehensive interventions.展开更多
Background:Light at night(LAN)has become a concern in interdisciplinary research in recent years.This global interdisciplinary study aimed to explore the exposure-lag-response association between LAN exposure and lung...Background:Light at night(LAN)has become a concern in interdisciplinary research in recent years.This global interdisciplinary study aimed to explore the exposure-lag-response association between LAN exposure and lung cancer incidence.Methods:LAN data were obtained from the Defense Meteorological Satellite Program’s Operational Linescan System.Data of lung cancer incidence,socio-demographic index,and smoking prevalence of populations in 201 countries/territories from 1992 to 2018 were collected from the Global Burden of Disease Study.Spearman correlation tests and population-weighted linear regression analysis were used to evaluate the correlation between LAN exposure and lung cancer incidence.A distributed lag nonlinear model(DLNM)was used to assess the exposure-lag effects of LAN exposure on lung cancer incidence.Results:The Spearman correlation coefficients were 0.286-0.355 and the population-weighted linear regression correlation coefficients were 0.361-0.527.After adjustment for socio-demographic index and smoking preva-lence,the Spearman correlation coefficients were 0.264-0.357 and the population-weighted linear regression correlation coefficients were 0.346-0.497.In the DLNM,the maximum relative risk was 1.04(1.02-1.06)at LAN exposure of 8.6 with a 2.6-year lag time.After adjustment for socio-demographic index and smoking prevalence,the maximum relative risk was 1.05(1.02-1.07)at LAN exposure of 8.6 with a 2.4-year lag time.Conclusion:High LAN exposure was associated with increased lung cancer incidence,and this effect had a specific lag period.Compared with traditional individual-level studies,this group-level study provides a novel paradigm of effective,efficient,and scalable screening for risk factors.展开更多
This paper considers the stabilization of non-homogeneous rotating body-beam system with the torque and nonlinear distributed controls. To stabilize the system, the authors propose the torque and nonlinear distributed...This paper considers the stabilization of non-homogeneous rotating body-beam system with the torque and nonlinear distributed controls. To stabilize the system, the authors propose the torque and nonlinear distributed controls applied on the disk and flexible beam respectively. As long as the angular velocity of the disk does not exceed the square root of the first eigenvalue of the related self-adjoint positive definite operator, the authors show that the torque and nonlinear distributed control laws suppress the system vibrations, in the sense that the beam vibrations are forced to decay exponentially to zero and the body rotates with a desired angular velocity.展开更多
This paper studies the stabilization problem of uniform Euler-Bernoulli beam with a nonlinear locally distributed feedback control. By virtue of nonlinear semigroup theory, energy-perturbed approach and polynomial mul...This paper studies the stabilization problem of uniform Euler-Bernoulli beam with a nonlinear locally distributed feedback control. By virtue of nonlinear semigroup theory, energy-perturbed approach and polynomial multiplier skill, the authors show that, corresponding to the different values of the parameters involved in the nonlinear locally distributed feedback control, the energy of the beam under the proposed feedback decays exponentially or in negative power of time t as t →∞.展开更多
This paper studies the problem of adaptive neural networks control(ANNC) for uncertain parabolic distributed parameter systems(DPSs) with nonlinear periodic time-varying parameter(NPTVP). Firstly, the uncertain nonlin...This paper studies the problem of adaptive neural networks control(ANNC) for uncertain parabolic distributed parameter systems(DPSs) with nonlinear periodic time-varying parameter(NPTVP). Firstly, the uncertain nonlinear dynamic and unknown periodic TVP are represented by using neural networks(NNs) and Fourier series expansion(FSE), respectively. Secondly, based on the ANNC and reparameterization approaches, two control algorithms are designed to make the uncertain parabolic DPSs with NPTVP asymptotically stable. The sufficient conditions of the asymptotically stable for the resulting closed-loop systems are also derived. Finally, a simulation is carried out to verify the effectiveness of the two control algorithms designed in this work.展开更多
In most of partially averaged Navier-Stokes(PANS)methods,the Reynolds stress is solved by a linear hypothesis isotropic model.They could not capture all kinds of vortexes in tubomachineries.In this paper,a PANS mode...In most of partially averaged Navier-Stokes(PANS)methods,the Reynolds stress is solved by a linear hypothesis isotropic model.They could not capture all kinds of vortexes in tubomachineries.In this paper,a PANS model is modified from the RNG k-?turbulence model and is used to investigate the influence of the nonlinear shear stress on the simulation of the high pressure gradient flows and the large curvature flows.Comparisons are made between the result obtained by using the PANS model modified from the RNG k-?model and that obtained by using the nonlinear PANS methods.The flow past a curved rectangular duct is calculated by using the PANS methods.The obtained nonlinear shear stress agrees well with the experimental results,especially in the high pressure gradient region.The calculation results show that the nonlinear PANS methods are more reliable than the linear PANS methods for the high pressure gradient flows,the large curvature flows,and they can be used to capture complex vortexes in a turbomachinary.展开更多
Climate change has resulted in an increase in the frequency and intensity of extreme cold weather events,but few multicity or multicounty researches have explored the association between cold spells and mortality risk...Climate change has resulted in an increase in the frequency and intensity of extreme cold weather events,but few multicity or multicounty researches have explored the association between cold spells and mortality risk and burden.We collected daily data on climate,sociodemo-graphic factors and mortality in 18 cities/counties across 11 geographical regions for the period of November to March 2014-2018.A distributed lag nonlinear model was used to examine the association between cold spells and mortality after adjustment for confounding factors.Twelve definitions of cold spells were used.Multi-meta regression analysis was applied to pool the impacts over different regions.Cold spells were significantly associated with all-cause mortality at lag 0-21(CRR:1.38,95%CI:1.21,1.57).In addition to respiratory diseases and cir-culatory system diseases,digestive,endocrine and nervous system diseases and injury were also affected by cold spells.The magnitude of the impacts of cold spells on mortality varied among the diseases investigated,with the highest risk estimate found for influenza and pneumonia(CRR:2.00,95%CI:1.45,2.76)and the lowest estimate found for injury(CRR:1.26,95%CI:1.09,1.46).The fraction of all-cause mortality attributable to cold spells was 2.31%(95%CI:0.90%,3.46%).Among the regional differences,the attributable burden of all-cause mortality was higher in rural areas and subtropical monsoon climate zone,with attributable fractions of 2.85%(95%CI:1.23%,4.11%)and 3.36%(95%CI:0.55%,5.35%),respectively.Cold spells increased mortality from a range of diseases.Women,older adults and residents of rural areas and subtropical monsoon climate zone were more vulnerable to cold spells impacts.The findings may help to formulate preventive strategies and early warning response plans to reduce mortality burden of extreme cold events.展开更多
Monitoring of viral signal in wastewater is considered a useful tool for monitoring the burden of COVID-19,especially during times of limited availability in testing.Studies have shown that COVID-19 hospitalizations a...Monitoring of viral signal in wastewater is considered a useful tool for monitoring the burden of COVID-19,especially during times of limited availability in testing.Studies have shown that COVID-19 hospitalizations are highly correlated with wastewater viral signals and the increases in wastewater viral signals can provide an early warning for increasing hospital admissions.The association is likely nonlinear and time-varying.This project employs a distributed lag nonlinear model(DLNM)(Gasparrini et al.,2010)to study the nonlinear exposure-response delayed association of the COVID-19 hospitalizations and SARS-CoV-2 wastewater viral signals using relevant data from Ottawa,Canada.We consider up to a 15-day time lag from the average of SARS-CoV N1 and N2 gene concen-trations to COVID-19 hospitalizations.The expected reduction in hospitalization is adjusted for vaccination efforts.A correlation analysis of the data verifies that COVID-19 hospital-izations are highly correlated with wastewater viral signals with a time-varying rela-tionship.Our DLNM based analysis yields a reasonable estimate of COVID-19 hospitalizations and enhances our understanding of the association of COVID-19 hospi-talizations with wastewater viral signals.展开更多
We investigate three kinds of strong laws of large numbers for capacities with a new notion of independently and identically distributed(IID) random variables for sub-linear expectations initiated by Peng.It turns out...We investigate three kinds of strong laws of large numbers for capacities with a new notion of independently and identically distributed(IID) random variables for sub-linear expectations initiated by Peng.It turns out that these theorems are natural and fairly neat extensions of the classical Kolmogorov's strong law of large numbers to the case where probability measures are no longer additive. An important feature of these strong laws of large numbers is to provide a frequentist perspective on capacities.展开更多
Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and q...Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics.展开更多
This study revisits the Fisher effect using a different empirical method that considers a potential nonlinear relationship between interest rates(treasury bond rates)and inflation in China.The rising uncertainty and a...This study revisits the Fisher effect using a different empirical method that considers a potential nonlinear relationship between interest rates(treasury bond rates)and inflation in China.The rising uncertainty and asymmetric information in financial markets between bond holders and bond issuers suggest such a potential nonlinear relationship.To this aim,we apply Shin et al.'s(2014)nonlinear autoregressive distributed lag(NARDL)model with asymmetric dynamic multipliers for the sample period 2002M7-2018M4.The empirical findings reveal symmetric and asymmetric partial Fisher effects for all sample bond rates in China.Furthermore,we find that 20-year bond rates experience the lowest partial Fisher effect.展开更多
基金supported by the Original Exploration Project of Natural Science Foundation of China(No.12150001)the National Key Research and Development Program of China(No.2018YFB1900400)+1 种基金the National Natural Science Foundation of China(No.11832019)the Nuclear Power Technology Innovation Center of Science Technology and Industry for National Defense of China(No.HDLCXZX-2021-HD-035)。
文摘The stress and the strain should be defined as statistical variables averaged over the representative volume elements for any real continuum system.It is shown that their nonlinear spatial distributions undermine the classical framework of solid mechanics and may cause non-ignorable errors to the solutions.With considering the high-order gradients of the stress and the strain,a two-step solution scheme is proposed to compensate for the influence.Through a revisit to three simple but typical problems,i.e.,the hole size-dependence of the fracture strength of perforated plates,the indentation depth-dependence of the measured elastic modulus by micro-indentation tests,and the tensile necking of metallic materials as well as hyperelastic materials,the effect of the nonlinear spatial distribution of stress and strain on solving these problems is illustrated.The observed size effect and the instability of deformation can be quantitatively explained if the effect is properly considered by the proposed method.
基金supported by The HongKong Polytechnic University Research Grants(No.1-BB81)grants from National Natural Science Foundation of China,Nos.10872078 and 10832012
文摘Precisely quantifying the strength of the proximal femur and accurately assessing hip fracture risk would enable those at high risk to be identified so that preventive interventions could be taken.Development of better measures of femoral strength using the clinically
文摘Objective:To explore the effects of daily mean temperature(°C),average daily air pressure(hPa),humidity(%),wind speed(m/s),particulate matter(PM)2.5(μg/m3)and PM10(μg/m3)on the admission rate of chronic kidney disease(CKD)patients admitted to the Second Affiliated Hospital of Harbin Medical University in Harbin and to identify the indexes and lag days that impose the most critical influence.Methods:The R language Distributed Lag Nonlinear Model(DLNM),Excel,and SPSS were used to analyze the disease and meteorological data of Harbin from 01 January 2010 to 31 December 2019 according to the inclusion and exclusion criteria.Results:Meteorological factors and air pollution influence the number of hospitalizations of CKD to vary degrees in cold regions,and differ in persistence or delay.Non-optimal temperature increases the risk of admission of CKD,high temperature increases the risk of obstructive kidney disease,and low temperature increases the risk of other major types of chronic kidney disease.The greater the temperature difference is,the higher its contribution is to the risk.The non-optimal wind speed and non-optimal atmospheric pressure are associated with increased hospital admissions.PM2.5 concentrations above 40μg/m3 have a negative impact on the results.Conclusion:Cold region meteorology and specific environment do have an impact on the number of hospital admissions for chronic kidney disease,and we can apply DLMN to describe the analysis.
基金the National Natural Science Foundation of China(No:81960351)Research Foundation for Advanced Talents of Hainan(No:822RC835)Province Natural Science Key Foundation of Hainan(No:ZDYF 2019125).
文摘Objective:To assess the correlation between atmospheric pollutants,meteorological factors,and emergency department visits for respiratory diseases in Haikou City.Methods:Daily data on atmospheric pollutants,meteorological factors,and emergency department visits for respiratory diseases in Haikou City from 2018 to 2021 were collected.The Spearman rank correlation test was used to analyze the correlation,and a distributed lag non-linear model was employed to analyze the health effects and lag impacts of environmental factors.Subgroup analyses were conducted based on sex and age.Results:According to the criteria of International Classification of Diseases(ICD-10:J00-J99),a total of 221913 cases were included,accounting for 21.3%of the total emergency department visits in Haikou City.For every 1℃increase in temperature,the risk of emergency department visits increased by 1.029%(95%CI 1.016%-1.042%).Relative humidity greater than 80%reduced the risk of visits,while higher atmospheric pressure(>1010 hpa)also decreased the likelihood of daily emergency department visits.Higher concentrations of PM_(2.5)(30-50μg/m^(3)),PM10(>60μg/m^(3)),and O_(3)(75-125μg/m^(3))were associated with increased visits.Higher temperatures(>25℃)have a greater impact on females and children aged 0-14 years,while males are more sensitive to low atmospheric pressure.Individuals aged 65 and above exhibited increased sensitivity to O_(3)concentration,and the effects of PM2.5,PM10,and O_(3)are more pronounced in individuals over 14 years old.Conclusions:Short-term exposure to high temperatures,particulate matter pollutants(PM_(2.5)and PM_(10)),and ozone(O_(3))is associated with increased emergency department visits for respiratory diseases.
文摘The sensitivity of collinear nonlinear nondestructive testing technique based on harmonic detection is high,but the results are vulnerable to interference from other nonlinear of experiment sources,which leads to this technology limited in industrial applications.To solve this problem,a non-collinear nonlinear ultrasonic testing experimental system is established based on non-collinear beam mixing technology.The non-collinear nonlinear response is observed in the steel and LY12 aluminum alloy.The results show that:1 Based on the benefits of space selection,mode conversion,frequency and steerable optional of non-collinear beam mixing technology,the interference of system nonlinear effects can be suppressed effectively;2 Mode conversion and beam mixing are present in steel and LY12 aluminum alloy,and the non-collinear non-linear response of LY12 aluminum alloy is stronger than steel and the measurement results are more obvious;3 The technology has the feasibility to evaluate the uniformity of material internal.
基金supported by the National Natural Science Foundation of China (Grant 11172087)
文摘The nonlinear dynamics of cantilevered piezoelectric beams is investigated under simultaneous parametric and external excitations. The beam is composed of a substrate and two piezoelectric layers and assumed as an Euler-Bernoulli model with inextensible deformation. A nonlinear distributed parameter model of cantilevered piezoelectric energy harvesters is proposed using the generalized Hamilton's principle. The proposed model includes geometric and inertia nonlinearity, but neglects the material nonlinearity. Using the Galerkin decomposition method and harmonic balance method, analytical expressions of the frequency-response curves are presented when the first bending mode of the beam plays a dominant role. Using these expressions, we investigate the effects of the damping, load resistance, electromechanical coupling, and excitation amplitude on the frequency-response curves. We also study the difference between the nonlinear lumped-parameter and distributed- parameter model for predicting the performance of the energy harvesting system. Only in the case of parametric excitation, we demonstrate that the energy harvesting system has an initiation excitation threshold below which no energy can be harvested. We also illustrate that the damping and load resistance affect the initiation excitation threshold.
基金supported by National Institute for Occupational Health and Poison Control,Chinese Center for Disease Control and Prevention Chemical Poisoning Treatment base and Health Emergency Team Operation[131031109000160007]
文摘Objective This study aimed to determine the spatiotemporal distribution and epidemiological characteristics of hospital admissions for carbon monoxide poisoning(COP)in Guangdong,China,from 2013 to 2020.Methods Data on age-and sex-specific numbers of hospital admissions due to COP in Guangdong(2013-2020)were collected.Daily temperatures were downloaded through the China Meteorological Data Sharing Service System.We analyzed temporal trends through time series decomposition and used spatial autocorrelation analysis to detect spatial clustering.The distributed lag nonlinear model was used to quantify the effects of temperature.Results There were 48,854 COP admissions over the study period.The sex ratio(male to female)was1:1.74.The concentration ratios(M)ranged from 0.73-0.82.The highest risk occurred in January(season index=3.59).Most cases were concentrated in the northern mountainous areas of Guangdong with high-high clustering.COP in the study region showed significant spatial autocorrelation,and the global Moran’s I value of average annual hospital admission rates for COP was 0.447(P<0.05).Low temperatures were associated with high hospital admission rates for COP,with a lag lasting 7 days.With a lag of 0 days,the effects of low temperatures[5th(12℃)]on COP were 2.24-3.81,as compared with the reference temperature[median(24℃)].Conclusion COP in Guangdong province showed significant temporal and spatial heterogeneity.Low temperature was associated with a high risk of COP,and the influence had a lag lasting 7 days.
基金Partially supported by projects:MNTR:174024APV:114-451-3605/2013
文摘We find an upper viscosity solution and give a proof of the existence-uniqueness in the space C^∞(t∈(0,∞);H2^s+2(R^n))∩C^0(t∈[0,∞);H^s(R^n)),s∈R,to the nonlinear time fractional equation of distributed order with spatial Laplace operator subject to the Cauchy conditions ∫0^2p(β)D*^βu(x,t)dβ=△xu(x,t)+f(t,u(t,x)),t≥0,x∈R^n,u(0,x)=φ(x),ut(0,x)=ψ(x),(0.1) where △xis the spatial Laplace operator,D*^β is the operator of fractional differentiation in the Caputo sense and the force term F satisfies the Assumption 1 on the regularity and growth. For the weight function we take a positive-linear combination of delta distributions concentrated at points of interval (0, 2), i.e., p(β) =m∑k=1bkδ(β-βk),0〈βk〈2,bk〉0,k=1,2,…,m.The regularity of the solution is established in the framework of the space C^∞(t∈(0,∞);C^∞(R^n))∩C^0(t∈[0,∞);C^∞(R^n))when the initial data belong to the Sobolev space H2^8(R^n),s∈R.
文摘Statistical analysis was done on simultaneous wave and wind using data recorded by discus-shape wave buoy. The area is located in the southern Caspian Sea near the Anzali Port. Recorded wave data were obtained through directional spectrum wave analysis. Recorded wind direction and wind speed were obtained through the related time series as well. For 12-month measurements(May 25 2007-2008), statistical calculations were done to specify the value of nonlinear auto-correlation of wave and wind using the probability distribution function of wave characteristics and statistical analysis in various time periods. The paper also presents and analyzes the amount of wave energy for the area mentioned on the basis of available database. Analyses showed a suitable comparison between the amounts of wave energy in different seasons. As a result, the best period for the largest amount of wave energy was known. Results showed that in the research period, the mean wave and wind auto correlation were about three hours. Among the probability distribution functions, i.e Weibull, Normal, Lognormal and Rayleigh, "Weibull" had the best consistency with experimental distribution function shown in different diagrams for each season. Results also showed that the mean wave energy in the research period was about 49.88 k W/m and the maximum density of wave energy was found in February and March, 2010.
基金funded by grants from Chinese Center for Disease Control and Prevention(102393220020010000017)
文摘Background Tuberculosis(TB)remains a pressing public health issue,posing a significant threat to individuals'well-being and lives.This study delves into the TB incidence in Chinese mainland during 2014-2021,aiming to gain deeper insights into their epidemiological characteristics and explore macro-level factors to enhance control and prevention.Methods TB incidence data in Chinese mainland from 2014 to 2021 were sourced from the National Notifiable Disease Reporting System(NNDRS).A two-stage distributed lag nonlinear model(DLNM)was constructed to evaluate the lag and non-linearity of daily average temperature(℃,Atemp),average relative humidity(%,ARH),average wind speed(m/s,AWS),sunshine duration(h,SD)and precipitation(mm,PRE)on the TB incidence.A spatial panel data model was used to assess the impact of demographic,medical and health resource,and economic factors on TB incidence.Results A total of 6,587,439 TB cases were reported in Chinese mainland during 2014-2021,with an average annual incidence rate of 59.17/100,000.The TB incidence decreased from 67.05/100,000 in 2014 to 46.40/100,000 in 2021,notably declining from 2018 to 2021(APC=-8.87%,95%CI:-11.97,-6.85%).TB incidence rates were higher among males,farmers,and individuals aged 65 years and older.Spatiotemporal analysis revealed a significant cluster in Xinjiang,Qinghai,and Xizang from March 2017 to June 2019(RR=3.94,P<0.001).From 2014 to 2021,the proportion of etiologically confirmed cases increased from 31.31%to 56.98%,and the time interval from TB onset to diagnosis shortened from 26 days(IQR:10-56 days)to 19 days(IQR:7-44 days).Specific meteorological conditions,including low temperature(<16.69℃),high relative humidity(>71.73%),low sunshine duration(<6.18 h)increased the risk of TB incidence,while extreme low wind speed(<2.79 m/s)decreased the risk.The spatial Durbin model showed positive associations between TB incidence rates and sex ratio(β=1.98),number of beds in medical and health institutions per 10,000 population(β=0.90),and total health expenses(β=0.55).There were negative associations between TB incidence rates and population(β=-1.14),population density(β=-0.19),urbanization rate(β=-0.62),number of medical and health institutions(β=-0.23),and number of health technicians per 10,000 population(β=-0.70).Conclusions Significant progress has been made in TB control and prevention in China,but challenges persist among some populations and areas.Varied relationships were observed between TB incidence and factors from meteorological,demographic,medical and health resource,and economic aspects.These findings underscore the importance of ongoing efforts to strengthen TB control and implement digital/intelligent surveillance for early risk detection and comprehensive interventions.
文摘Background:Light at night(LAN)has become a concern in interdisciplinary research in recent years.This global interdisciplinary study aimed to explore the exposure-lag-response association between LAN exposure and lung cancer incidence.Methods:LAN data were obtained from the Defense Meteorological Satellite Program’s Operational Linescan System.Data of lung cancer incidence,socio-demographic index,and smoking prevalence of populations in 201 countries/territories from 1992 to 2018 were collected from the Global Burden of Disease Study.Spearman correlation tests and population-weighted linear regression analysis were used to evaluate the correlation between LAN exposure and lung cancer incidence.A distributed lag nonlinear model(DLNM)was used to assess the exposure-lag effects of LAN exposure on lung cancer incidence.Results:The Spearman correlation coefficients were 0.286-0.355 and the population-weighted linear regression correlation coefficients were 0.361-0.527.After adjustment for socio-demographic index and smoking preva-lence,the Spearman correlation coefficients were 0.264-0.357 and the population-weighted linear regression correlation coefficients were 0.346-0.497.In the DLNM,the maximum relative risk was 1.04(1.02-1.06)at LAN exposure of 8.6 with a 2.6-year lag time.After adjustment for socio-demographic index and smoking prevalence,the maximum relative risk was 1.05(1.02-1.07)at LAN exposure of 8.6 with a 2.4-year lag time.Conclusion:High LAN exposure was associated with increased lung cancer incidence,and this effect had a specific lag period.Compared with traditional individual-level studies,this group-level study provides a novel paradigm of effective,efficient,and scalable screening for risk factors.
基金supported by the National Natural Science Foundation of China under Grant Nos.61273130 and 61673061
文摘This paper considers the stabilization of non-homogeneous rotating body-beam system with the torque and nonlinear distributed controls. To stabilize the system, the authors propose the torque and nonlinear distributed controls applied on the disk and flexible beam respectively. As long as the angular velocity of the disk does not exceed the square root of the first eigenvalue of the related self-adjoint positive definite operator, the authors show that the torque and nonlinear distributed control laws suppress the system vibrations, in the sense that the beam vibrations are forced to decay exponentially to zero and the body rotates with a desired angular velocity.
基金This research is supported by the National Science Foundation of China under Grant Nos. 10671166 and 60673101.
文摘This paper studies the stabilization problem of uniform Euler-Bernoulli beam with a nonlinear locally distributed feedback control. By virtue of nonlinear semigroup theory, energy-perturbed approach and polynomial multiplier skill, the authors show that, corresponding to the different values of the parameters involved in the nonlinear locally distributed feedback control, the energy of the beam under the proposed feedback decays exponentially or in negative power of time t as t →∞.
基金supported by the National Natural Science Foundation of China (Grant No. 61573013)。
文摘This paper studies the problem of adaptive neural networks control(ANNC) for uncertain parabolic distributed parameter systems(DPSs) with nonlinear periodic time-varying parameter(NPTVP). Firstly, the uncertain nonlinear dynamic and unknown periodic TVP are represented by using neural networks(NNs) and Fourier series expansion(FSE), respectively. Secondly, based on the ANNC and reparameterization approaches, two control algorithms are designed to make the uncertain parabolic DPSs with NPTVP asymptotically stable. The sufficient conditions of the asymptotically stable for the resulting closed-loop systems are also derived. Finally, a simulation is carried out to verify the effectiveness of the two control algorithms designed in this work.
基金supported by the National Natural Science Foundation of China(Grant Nos.51406010,51479166)
文摘In most of partially averaged Navier-Stokes(PANS)methods,the Reynolds stress is solved by a linear hypothesis isotropic model.They could not capture all kinds of vortexes in tubomachineries.In this paper,a PANS model is modified from the RNG k-?turbulence model and is used to investigate the influence of the nonlinear shear stress on the simulation of the high pressure gradient flows and the large curvature flows.Comparisons are made between the result obtained by using the PANS model modified from the RNG k-?model and that obtained by using the nonlinear PANS methods.The flow past a curved rectangular duct is calculated by using the PANS methods.The obtained nonlinear shear stress agrees well with the experimental results,especially in the high pressure gradient region.The calculation results show that the nonlinear PANS methods are more reliable than the linear PANS methods for the high pressure gradient flows,the large curvature flows,and they can be used to capture complex vortexes in a turbomachinary.
基金the project of Scientific Investigation on Regional Climate-sensitive Diseases in China (grant number:2017FY101201)supported by the Ministry of Science and Technology for Basic Resource Survey。
文摘Climate change has resulted in an increase in the frequency and intensity of extreme cold weather events,but few multicity or multicounty researches have explored the association between cold spells and mortality risk and burden.We collected daily data on climate,sociodemo-graphic factors and mortality in 18 cities/counties across 11 geographical regions for the period of November to March 2014-2018.A distributed lag nonlinear model was used to examine the association between cold spells and mortality after adjustment for confounding factors.Twelve definitions of cold spells were used.Multi-meta regression analysis was applied to pool the impacts over different regions.Cold spells were significantly associated with all-cause mortality at lag 0-21(CRR:1.38,95%CI:1.21,1.57).In addition to respiratory diseases and cir-culatory system diseases,digestive,endocrine and nervous system diseases and injury were also affected by cold spells.The magnitude of the impacts of cold spells on mortality varied among the diseases investigated,with the highest risk estimate found for influenza and pneumonia(CRR:2.00,95%CI:1.45,2.76)and the lowest estimate found for injury(CRR:1.26,95%CI:1.09,1.46).The fraction of all-cause mortality attributable to cold spells was 2.31%(95%CI:0.90%,3.46%).Among the regional differences,the attributable burden of all-cause mortality was higher in rural areas and subtropical monsoon climate zone,with attributable fractions of 2.85%(95%CI:1.23%,4.11%)and 3.36%(95%CI:0.55%,5.35%),respectively.Cold spells increased mortality from a range of diseases.Women,older adults and residents of rural areas and subtropical monsoon climate zone were more vulnerable to cold spells impacts.The findings may help to formulate preventive strategies and early warning response plans to reduce mortality burden of extreme cold events.
基金supported by the Natural Sciences and Engineering Research Council of Canada(NSERC EIDM)。
文摘Monitoring of viral signal in wastewater is considered a useful tool for monitoring the burden of COVID-19,especially during times of limited availability in testing.Studies have shown that COVID-19 hospitalizations are highly correlated with wastewater viral signals and the increases in wastewater viral signals can provide an early warning for increasing hospital admissions.The association is likely nonlinear and time-varying.This project employs a distributed lag nonlinear model(DLNM)(Gasparrini et al.,2010)to study the nonlinear exposure-response delayed association of the COVID-19 hospitalizations and SARS-CoV-2 wastewater viral signals using relevant data from Ottawa,Canada.We consider up to a 15-day time lag from the average of SARS-CoV N1 and N2 gene concen-trations to COVID-19 hospitalizations.The expected reduction in hospitalization is adjusted for vaccination efforts.A correlation analysis of the data verifies that COVID-19 hospital-izations are highly correlated with wastewater viral signals with a time-varying rela-tionship.Our DLNM based analysis yields a reasonable estimate of COVID-19 hospitalizations and enhances our understanding of the association of COVID-19 hospi-talizations with wastewater viral signals.
基金supported by National Natural Science Foundation of China(Grant No.11231005)
文摘We investigate three kinds of strong laws of large numbers for capacities with a new notion of independently and identically distributed(IID) random variables for sub-linear expectations initiated by Peng.It turns out that these theorems are natural and fairly neat extensions of the classical Kolmogorov's strong law of large numbers to the case where probability measures are no longer additive. An important feature of these strong laws of large numbers is to provide a frequentist perspective on capacities.
基金We thank Professor Antonio Gasparrini for providing assistance during statistical analysis.This work was supported by the National Key Research and Development Program of China(2018YFA0606200)Guangzhou Science and Technology Project(201704020194)+3 种基金and the Guangdong Health Innovation Platform.The funders were not involved in the research and preparation of the article,including study designcollection,analysis,and interpretation of datawriting of the articleand the decision to submit it for publication.
文摘Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics.
文摘This study revisits the Fisher effect using a different empirical method that considers a potential nonlinear relationship between interest rates(treasury bond rates)and inflation in China.The rising uncertainty and asymmetric information in financial markets between bond holders and bond issuers suggest such a potential nonlinear relationship.To this aim,we apply Shin et al.'s(2014)nonlinear autoregressive distributed lag(NARDL)model with asymmetric dynamic multipliers for the sample period 2002M7-2018M4.The empirical findings reveal symmetric and asymmetric partial Fisher effects for all sample bond rates in China.Furthermore,we find that 20-year bond rates experience the lowest partial Fisher effect.