The basic rhythms of nature that left their imprint on the existence of all living organism on the Earth, arose under the influence of the Earth’s rotation relative to the Sun, the Moon and other planets and stars of...The basic rhythms of nature that left their imprint on the existence of all living organism on the Earth, arose under the influence of the Earth’s rotation relative to the Sun, the Moon and other planets and stars of the Universe. This periodicity gave rise to the rhythm that has become essential for their life. Life is a continual chemical process of building up and breaking down of organic substances, which results from the substance exchange between an organism and the environment. This makes it impossible for a living organism to exist without the external environment. Since 1978-1979 we have been carrying out a task-oriented research with the aim to approximate the moment when we are able to answer all these questions. Daily fluctuations of cardiac and motor activity of the fetus have been studied (uninterrupted daily recording of fetal ECG);polysomnography of nocturnal sleep was recorded;daily fluctuations of endocrine system activity in the pregnant were studied. A correlation was made between the functional state of maternal sleep-wakefulness biological rhythm, biological clock of the human fetus and the “light-darkness” cycle of a 24-hour solar day. In the process of the study we have developed an original method of day-to-day analysis of maternal and fetal ECGs. It has been established that a healthy fetus has distinct, diurnal variations of physiological functions. The fetal biorhythms coordinate with the status of the maternal organism being, however, in an opposite phase. The curve of the dynamics of fetal physiological system functioning shows a biphasic nature (one-phase in adults). “Active” and “quiet” (sleep-like) periods have been singled out in the human fetus. No reaction is observed in “quiet” periods. However, the “zero”-type fetal reaction recorded by us within the period from 2 p.m. to 9 p.m. does not indicate unsatisfactory condition of the fetus but rather is suggestive of a definite reduction of functional levels of the fetal physiological systems, which is necessary for vital activity. Although conventionally recognized as an indicator of poor state of the fetus, this type only calls for precise attention when recorded in fetal “active” hours. The present study has been the first in the world’s medicine and biorhythmology to detect and establish the daily rhythms of cardiac and motor activity in the human fetus.展开更多
Dear editor,In July 2015,a 39-year-old gravida 2,para 0 lady at 35 weeks’gestation was found collapsed at home and sent to the emergency department(ED)by ambulance.She had a background of chronic hypertension on anti...Dear editor,In July 2015,a 39-year-old gravida 2,para 0 lady at 35 weeks’gestation was found collapsed at home and sent to the emergency department(ED)by ambulance.She had a background of chronic hypertension on antihypertensives and aspirin,but repeatedly refused inpatient treatment for her uncontrolled hypertension.展开更多
Extraskeletal osteosarcoma (ESO) is a rare malignant mesenchymal neoplasm accounting for 1% - 2% of all soft tissue sarcomas that produce osteoid, bone, and/or chondroid material. Here we report the first case of a re...Extraskeletal osteosarcoma (ESO) is a rare malignant mesenchymal neoplasm accounting for 1% - 2% of all soft tissue sarcomas that produce osteoid, bone, and/or chondroid material. Here we report the first case of a retroperitoneal ESO in a 35-year-old pregnant woman. A retroperitoneal ESO was incidentally found at cesarean section. Despite treatment, she rapidly died from wide spread dissemination. We focus on histological characteristics including immunohistochemical results and differential diagnosis of ESO.展开更多
Valsalva retinopathy is caused by a sudden increase in intra-thoracic or abdominal pressure, following forced expiration, with mouth and nose closed (Valsalva maneuver). We report a case of Valsalva retinopathy in a p...Valsalva retinopathy is caused by a sudden increase in intra-thoracic or abdominal pressure, following forced expiration, with mouth and nose closed (Valsalva maneuver). We report a case of Valsalva retinopathy in a pregnant woman. A 36 years old patient, pregnant at 24 weeks of amenorrhea, who consulted for sudden visual acuity decrease of the left eye, evolving since 24 hours after Valsalva maneuvers to calm down her panic and control her breathing. The refraction has demonstrated a decrease of visual acuity in the left eye to “can see a hand moving”, while the visual acuity remained normal in the right eye. Spontaneous evolution was marked by a fast and progressive reduction of hemorrhage and progressive recovery of vision in the left eye. Valsava retinopathy was first described in 1972 by Thomas Duane. Physical activity is usually found before it occurs. Many situations are usually associated to this occurrence among which: pregnancy, vomiting, weightlifting or trauma. Regression of this hemorrhage without sequelae is usual. But sometimes, we need a Nd:Yag laser treatment or surgery to evacuate the blood.展开更多
We presented a case of a 32-week pregnant woman with coronavirus disease 2019 and tuberculosis delivering a healthy baby.She was treated with antituberculosis and other symptomatic treatments,and the nucleic acid test...We presented a case of a 32-week pregnant woman with coronavirus disease 2019 and tuberculosis delivering a healthy baby.She was treated with antituberculosis and other symptomatic treatments,and the nucleic acid test;the sputum tuberculosis bacterial smear turned negative;and the symptoms were significantly relieved.展开更多
虽然妊娠期合并恶性肿瘤较为罕见,但随着女性妊娠期年龄的增大、头颈部癌症(head and neck cancer,HNC)患者的年轻化,妊娠期合并HNC的发病率略有增加。然而,目前临床尚缺乏关于妊娠期HNC的规范化诊疗标准。本研究通过系统检索PubMed数据...虽然妊娠期合并恶性肿瘤较为罕见,但随着女性妊娠期年龄的增大、头颈部癌症(head and neck cancer,HNC)患者的年轻化,妊娠期合并HNC的发病率略有增加。然而,目前临床尚缺乏关于妊娠期HNC的规范化诊疗标准。本研究通过系统检索PubMed数据库,评估孕妇(含围产期)患HNC的频率、肿瘤类型、相关因素和特异性生物标志物,并依据循证医学证据,对妊娠期合并HNC的研究进行综述,以期为临床工作提供指导。展开更多
目的明确孕妇分娩恐惧的危险因素。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国知网、万方数据知识服务平台和维普中文科技期刊数据库中有关孕妇分娩恐惧的研究。使用RevMan 5.4软件进行Meta分...目的明确孕妇分娩恐惧的危险因素。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国知网、万方数据知识服务平台和维普中文科技期刊数据库中有关孕妇分娩恐惧的研究。使用RevMan 5.4软件进行Meta分析。结果共纳入13篇研究。文化程度[OR=3.24,95%CI(1.26,8.30),P=0.010]、经济状况[OR=2.78,95%CI(1.69,4.59),P<0.001]、产前教育[OR=3.14,95%CI(2.27,4.33),P<0.001]、偏好分娩方式[OR=4.28,95%CI(2.56,7.15),P<0.001]、非计划妊娠[OR=5.27,95%CI(2.41,11.52),P<0.001]、妊娠并发症[OR=5.07,95%CI(2.03,12.71),P=0.001]、负面分娩经历[OR=7.98,95%CI(5.57,11.42),P<0.001]、社会支持[OR=2.04,95%CI(1.22,3.41),P=0.007]、焦虑和抑郁[OR=6.77,95%CI(4.72,9.72),P<0.001]是孕妇发生分娩恐惧的危险因素。结论文化程度低、经济状况差、未参加产前教育、偏好剖宫产分娩、非计划妊娠、妊娠并发症、负面分娩经历、社会支持低、焦虑和抑郁是孕妇发生分娩恐惧的危险因素,未来应采取针对性干预措施预防和降低孕妇分娩恐惧的发生。展开更多
文摘The basic rhythms of nature that left their imprint on the existence of all living organism on the Earth, arose under the influence of the Earth’s rotation relative to the Sun, the Moon and other planets and stars of the Universe. This periodicity gave rise to the rhythm that has become essential for their life. Life is a continual chemical process of building up and breaking down of organic substances, which results from the substance exchange between an organism and the environment. This makes it impossible for a living organism to exist without the external environment. Since 1978-1979 we have been carrying out a task-oriented research with the aim to approximate the moment when we are able to answer all these questions. Daily fluctuations of cardiac and motor activity of the fetus have been studied (uninterrupted daily recording of fetal ECG);polysomnography of nocturnal sleep was recorded;daily fluctuations of endocrine system activity in the pregnant were studied. A correlation was made between the functional state of maternal sleep-wakefulness biological rhythm, biological clock of the human fetus and the “light-darkness” cycle of a 24-hour solar day. In the process of the study we have developed an original method of day-to-day analysis of maternal and fetal ECGs. It has been established that a healthy fetus has distinct, diurnal variations of physiological functions. The fetal biorhythms coordinate with the status of the maternal organism being, however, in an opposite phase. The curve of the dynamics of fetal physiological system functioning shows a biphasic nature (one-phase in adults). “Active” and “quiet” (sleep-like) periods have been singled out in the human fetus. No reaction is observed in “quiet” periods. However, the “zero”-type fetal reaction recorded by us within the period from 2 p.m. to 9 p.m. does not indicate unsatisfactory condition of the fetus but rather is suggestive of a definite reduction of functional levels of the fetal physiological systems, which is necessary for vital activity. Although conventionally recognized as an indicator of poor state of the fetus, this type only calls for precise attention when recorded in fetal “active” hours. The present study has been the first in the world’s medicine and biorhythmology to detect and establish the daily rhythms of cardiac and motor activity in the human fetus.
文摘Dear editor,In July 2015,a 39-year-old gravida 2,para 0 lady at 35 weeks’gestation was found collapsed at home and sent to the emergency department(ED)by ambulance.She had a background of chronic hypertension on antihypertensives and aspirin,but repeatedly refused inpatient treatment for her uncontrolled hypertension.
文摘Extraskeletal osteosarcoma (ESO) is a rare malignant mesenchymal neoplasm accounting for 1% - 2% of all soft tissue sarcomas that produce osteoid, bone, and/or chondroid material. Here we report the first case of a retroperitoneal ESO in a 35-year-old pregnant woman. A retroperitoneal ESO was incidentally found at cesarean section. Despite treatment, she rapidly died from wide spread dissemination. We focus on histological characteristics including immunohistochemical results and differential diagnosis of ESO.
文摘Valsalva retinopathy is caused by a sudden increase in intra-thoracic or abdominal pressure, following forced expiration, with mouth and nose closed (Valsalva maneuver). We report a case of Valsalva retinopathy in a pregnant woman. A 36 years old patient, pregnant at 24 weeks of amenorrhea, who consulted for sudden visual acuity decrease of the left eye, evolving since 24 hours after Valsalva maneuvers to calm down her panic and control her breathing. The refraction has demonstrated a decrease of visual acuity in the left eye to “can see a hand moving”, while the visual acuity remained normal in the right eye. Spontaneous evolution was marked by a fast and progressive reduction of hemorrhage and progressive recovery of vision in the left eye. Valsava retinopathy was first described in 1972 by Thomas Duane. Physical activity is usually found before it occurs. Many situations are usually associated to this occurrence among which: pregnancy, vomiting, weightlifting or trauma. Regression of this hemorrhage without sequelae is usual. But sometimes, we need a Nd:Yag laser treatment or surgery to evacuate the blood.
基金provincial and ministerial joint project of the State Key Laboratory for the Prevention and Treatment of High Morbidity in Central Asia(SKL-HIDCA-2019-ZY4)Prevention and Treatment of Major Infectious Diseases such as AIDS and Hepatitis(SQ2018ZX100302).
文摘We presented a case of a 32-week pregnant woman with coronavirus disease 2019 and tuberculosis delivering a healthy baby.She was treated with antituberculosis and other symptomatic treatments,and the nucleic acid test;the sputum tuberculosis bacterial smear turned negative;and the symptoms were significantly relieved.
文摘虽然妊娠期合并恶性肿瘤较为罕见,但随着女性妊娠期年龄的增大、头颈部癌症(head and neck cancer,HNC)患者的年轻化,妊娠期合并HNC的发病率略有增加。然而,目前临床尚缺乏关于妊娠期HNC的规范化诊疗标准。本研究通过系统检索PubMed数据库,评估孕妇(含围产期)患HNC的频率、肿瘤类型、相关因素和特异性生物标志物,并依据循证医学证据,对妊娠期合并HNC的研究进行综述,以期为临床工作提供指导。
文摘目的明确孕妇分娩恐惧的危险因素。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国知网、万方数据知识服务平台和维普中文科技期刊数据库中有关孕妇分娩恐惧的研究。使用RevMan 5.4软件进行Meta分析。结果共纳入13篇研究。文化程度[OR=3.24,95%CI(1.26,8.30),P=0.010]、经济状况[OR=2.78,95%CI(1.69,4.59),P<0.001]、产前教育[OR=3.14,95%CI(2.27,4.33),P<0.001]、偏好分娩方式[OR=4.28,95%CI(2.56,7.15),P<0.001]、非计划妊娠[OR=5.27,95%CI(2.41,11.52),P<0.001]、妊娠并发症[OR=5.07,95%CI(2.03,12.71),P=0.001]、负面分娩经历[OR=7.98,95%CI(5.57,11.42),P<0.001]、社会支持[OR=2.04,95%CI(1.22,3.41),P=0.007]、焦虑和抑郁[OR=6.77,95%CI(4.72,9.72),P<0.001]是孕妇发生分娩恐惧的危险因素。结论文化程度低、经济状况差、未参加产前教育、偏好剖宫产分娩、非计划妊娠、妊娠并发症、负面分娩经历、社会支持低、焦虑和抑郁是孕妇发生分娩恐惧的危险因素,未来应采取针对性干预措施预防和降低孕妇分娩恐惧的发生。
