Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients...Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.展开更多
Doxorubicin is an anthracycline antibiotic.As a broad-spectrum antitumor drug,it is widely used in clinic.However,doxorubicin is dose-dependent and shows obvious cardiotoxicity,which limits its clinical application.At...Doxorubicin is an anthracycline antibiotic.As a broad-spectrum antitumor drug,it is widely used in clinic.However,doxorubicin is dose-dependent and shows obvious cardiotoxicity,which limits its clinical application.At present,the mechanism of doxorubicin induced cardiotoxicity has not been fully clarified.Reducing cardiotoxicity and improving the scope of clinical application have become the focus of research in recent years.This paper reviews the mechanism of doxorubicin cardiotoxicity and the prevention and treatment of doxorubicin cardiotoxicity with traditional Chinese medicine,in order to provide reference for the combined application of doxorubicin.展开更多
Objective:This paper aims to discuss the prevention and treatment strategies of gastrointestinal diseases in college students.Methods:A sample of 60 college students suffering from gastrointestinal diseases,from Augus...Objective:This paper aims to discuss the prevention and treatment strategies of gastrointestinal diseases in college students.Methods:A sample of 60 college students suffering from gastrointestinal diseases,from August 2021 to August 2022,was used to discuss the symptoms,causes,prevention strategies,and treatment strategies of gastrointestinal diseases based on questionnaire survey.Results:The high-incidence types of gastrointestinal diseases in college students mainly included chronic gastritis,acute gastritis,duodenal ulcer,and dyspepsia,which were closely related to mental state,diet,and living habits.Conclusion:There are many causes of gastrointestinal diseases in college students.During the period of active symptomatic treatment,it is necessary to focus on the prevention of gastrointestinal diseases in colleges and universities,correct the unhealthy lifestyle of students,and reduce the risk of gastrointestinal diseases.展开更多
Corona virus disease 2019(COVID-19)infection has become a major public health issue affecting human health.The main goal of epidemic prevention and control at the current stage in China is to“protect people’s health...Corona virus disease 2019(COVID-19)infection has become a major public health issue affecting human health.The main goal of epidemic prevention and control at the current stage in China is to“protect people’s health and prevent severe cases”.Patients with lung cancer who receive antitumor therapy have low immunity,and the risk of severe illness and death once infected is much higher than healthy people,so they are vulnerable to COVID-19 infection.At present,less attention has been paid to the prevention and treatment of COVID-19 infection in patients with lung cancer in domestic guidelines and consensus.Based on the published data in China and abroad,we proposed recommendations and formed expert consensus on the vaccination of COVID-19,the use of neutralizing antibodies and small molecule antiviral drugs for patients with lung cancer,for physician’s reference.展开更多
Seeds of flax or linseed(Linum usitatissimum L.)are important nutraceutical foods with antioxidant,anti-inflammatory,estrogenic,laxative,and antibacterial properties.Flaxseed oil and seeds are the richest vegetarian s...Seeds of flax or linseed(Linum usitatissimum L.)are important nutraceutical foods with antioxidant,anti-inflammatory,estrogenic,laxative,and antibacterial properties.Flaxseed oil and seeds are the richest vegetarian source of omega-3 fatty acids.Consumption of flaxseeds helps in prevention and control of cardiovascular disease,neurodegenerative disorders,obesity,diabetes mellitus,polycystic ovary syndrome,gout,liver and kidney dysfunction,oxidative stress-related diseases,post-menopausal symptoms,osteoporosis,irritable bowel syndrome,dry eye disease,cystic fibrosis,diarrhea,and cancer,particularly of the mammary and prostate gland cancer.Of late,flaxseed is gaining more importance not only because of its industrial values but also due to its nutraceutical and pharmaceutical properties.The literature review was performed using PubMed,Scopus,PubMed Central,Google Scholar,and Web of Science from 1995 onwards.Data was also obtained from websites/books/book chapters.展开更多
Objective:Using big data mining technology and network pharmacology,this study aimed to identify the dominant traditional Chinese medicine(TCM)for the prophylaxis and treatment of severe Corona Virus Disease 2019(COVI...Objective:Using big data mining technology and network pharmacology,this study aimed to identify the dominant traditional Chinese medicine(TCM)for the prophylaxis and treatment of severe Corona Virus Disease 2019(COVID-19),predict the pharmacological mechanism of the dominant anti-epidemic TCM,and provide clinical guidance for COVID-19 prevention and control.Methods:The Traditional Chinese Medicine Inheritance Computing Platform V3.0 was utilized to identify the high-frequency TCM in the adult severe prescriptions of the national Diagnosis and Treatment Plan for COVID-19(Trial 10th edition)and the TCM prophylaxis and cure plan for COVID-19 in 27 regions.The active ingredients and potential targets of the high-frequency core drugs were analyzed using Traditional Chinese Medicine Systems Pharmacology Technology Platform,Traditional Chinese Medicine Integrated Database,and Traditional Chinese Medicine Encyclopedia Database,and the network of“core drug active ingredient-potential targets”was obtained.The String platform was used to establish the protein-protein interaction structure chart,and Cytoscape software was used for visualization and network topology analysis to identify pivotal targets.Signal pathway enrichment analysis of the core targets was performed,and the affinity of the active components entering the blood was predicted by docking with the related targets of the novel coronavirus.Results:Ellagic acid,Vestitol,naringin,dehydroglyasperins C,quercetin,and kaemol were identified as 67 active constituents in the blood.After docking the active constituents with angiotensin-converting enzyme II,3C-likeProteinase,and tyrosine protein kinase receptor UFO,they all showed good affinity.The pivotal targets mainly involved inflammatory factors such as IL-6 and TNF.Pathway concentration analysis of gene ontology and Kyoto Encyclopedia of Genes and Genomes pathways focused on inflammatory and immune-related pathways such as the TNF signaling pathway.Conclusion:The high-frequency core drugs may act on the body through active components such as ellagic acid,Vestitol,naringin,dehydroglyasperins C,quercetin,and kaemol.Inflammatory and related immune pathways,such as the TNF signaling pathway,may suppress cytokine storms and effectively treat patients with severe COVID-19.展开更多
Chronic venous insufficiency is characterized by high incidence,difficult treatment and high recurrence rate.Traditional Chinese Medicine Preventive Treatment Theory is one of the important core contents in the theory...Chronic venous insufficiency is characterized by high incidence,difficult treatment and high recurrence rate.Traditional Chinese Medicine Preventive Treatment Theory is one of the important core contents in the theory of TCM.By using the theory of Traditional Chinese Medicine Preventive Treatment,using the theory of“prevention before illness,prevention the disease continues to change and prevention repeated when the disease has been cured”,can reduce the incidence rate effectively,improve the effect of clinical treatment,it is also to enrich and develop the theory of Traditional Chinese Medicine Preventive Treatment.展开更多
While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID‑19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the ...While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID‑19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the immune function and relieving symptoms in COVID‑19 patients.This article elaborates the long history of Tuina in treating and preventing epidemic diseases and its effect in improving the immune function.It also introduces some special Tuina methods,for instance,sputum drainage by the back‑patting method to enable the discharge of sputum;slant‑scrubbing method applied on the hypochondriac regions to bring the effect of soothing the liver to regulate qi,which may also relieve anxiety of patients with COVID‑19;and spine‑pinching method to enhance human resistance to diseases,which is more suitable for the elderly and for children with mild or common types of COVID‑19 and can also be used for health care and disease prevention among the general population.Tuina methods for children using the common children’s specific Tuina points and manipulations to improve children’s body constitution are also mentioned in the article.Self‑acupoint Tuina for health care,including acupoints for prevention purposes,acupoints for early clinical stage(mild stage)and recovery stage,as well as acupoints for children health care and specific operations,is also illustrated in the article.Moreover,basic exercises for health care,such as eight‑section brocade,Shaolin internal exercises,six‑character formula,and change of tendons,are also presented.In the final analysis,this article is aimed at some ideas and feasible applications of Tuina therapy in the prevention and treatment of COVID‑19,in the hope to provide some worthy experience and introduce methods in preventing and fighting against COVID‑19 to people all over the world.展开更多
While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID-19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the ...While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID-19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the immune function and relieving symptoms in COVID-19 patients.This article elaborates the long history of Tuina in treating and preventing epidemic diseases and its effect in improving the immune function.It also introduces some special Tuina methods,lor instance,sputum drainage by the back-patting method to enable the discharge of sputum;slant-scrubbing method applied on the hypochondriac regions to bring the effect of soothing the liver to regulate qi,which may also relieve anxiety of patients with COVID-19;and spine-pinching method to enhance human resistance to diseases,which is more suitable for the elderly and for children with mild or common types of COVID-19 and can also be used for health care and disease prevention among the general population.Tuina methods for children using the common childreifs specific Tuina points and manipulations to improve children’s body constitution are also mentioned in the article.Self-acupoint Tuina for health care,including acupoints for prevention purposes,acupoints for early clinical stage(mild stage)and recovery stage,as well as acupoints for children health care and specific operations,is also illustrated in the article.Moreover,basic exercises for health care,such as eight-section brocade,Shaolin internal exercises,six-character formula,and change of tendons,are also presented.In the final analysis,this article is aimed at some ideas and feasible applications of Tuina therapy in the prevention and treatment of COVID-19,in the hope to provide some worthy experience and introduce methods in preventing and fighting against COVID-19 to people all over the world.展开更多
Objective:The objective of this study is to investigate the risk factors for the occurrence of lower limb lymphedema in patients with endometrial cancer after surgery and to make recommendations for prevention and tre...Objective:The objective of this study is to investigate the risk factors for the occurrence of lower limb lymphedema in patients with endometrial cancer after surgery and to make recommendations for prevention and treatment.Materials and Methods:We retrospectively reviewed the clinical data of 135 patients with endometrial cancer treated in the Department of Gynecology of the Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine from January 2013 to December 2019 and analyzed the risk factors of lower limb lymphedema in patients with endometrial cancer after surgery using single factor analysis and multi-factor logistic regression analysis.Results:The incidence of postoperative lower limb lymphedema in patients with endometrial cancer was 11.11%.The results of one-way Chi-square test analysis showed that body mass index(BMI),surgical method,number of lymph node dissection,and radiotherapy were related to the occurrence of lower limb lymphedema,and multi-factor logistic analysis showed that BMI(odds ratio[OR]=6.207),number of lymph node dissection(OR=4.223),and radiotherapy(OR=8.081)were the risk factors for lower limb lymphedema after endometrial cancer surgery.Conclusion:Patients with endometrial cancer with BMI≥≥25 kg/m^(2),high number of lymph node dissection,and postoperative radiotherapy are more likely to develop lower limb lymphedema,and they should be given priority attention and timely preventive and curative measures.展开更多
Through the painstaking efforts,the situation of epidemic prevention and control is now developing in a positive direction.Nutritional Diet health management is an important part of health management.The main objectiv...Through the painstaking efforts,the situation of epidemic prevention and control is now developing in a positive direction.Nutritional Diet health management is an important part of health management.The main objective of nutritional diet health management is to improve the clinical outcomes,quality of life and cost-effectiveness ratio of patients with COVID-19 through standardized nutritional support,nutritional diet supplement and medical nutritional diet therapy,for the benefit of patients with COVID-19.展开更多
Objective:To review the research progress of using Chinese medicine ginseng to prevent and treat AIDS in China.Methods:Based on the method of TCM syndrome differentiation,Chinese medical researchers divided AIDS into ...Objective:To review the research progress of using Chinese medicine ginseng to prevent and treat AIDS in China.Methods:Based on the method of TCM syndrome differentiation,Chinese medical researchers divided AIDS into four types:heat toxin stagnation type,Qi and blood deficiency type,stasis and internal resistance type,and Qi and Yin injury type.Results:The therapeutic effects of the compound preparation of traditional Chinese medicine were significant,such as Aikang capsule,Tangcao tablet,Wuweilingqi capsule,Aining granule,compound Sanhuang powder,etc.Astragalus,licorice,honeysuckle,Scutellaria,bupleurum,Salvia miltiorrhiza,Viola,Hedyotis diffusa and other 8 kinds of traditional Chinese medicine have been proved to have anti HIV effect.Conclusion:Among the 27 kinds of Chinese medicine ginseng,Andrographis paniculata,Viola,Arnebia,Arctium lappa,Sophora flavescens,honeysuckle,Guanzhong,Prunella,Coptis,Wolfberry,Wedelia and epimedium have been proved to have the effect of preventing HIV replication.展开更多
Objective:To observe the clinical effect of traditional Chinese medicine on the prevention and treatment ofjuvenile mild myopia.Methods:One hundred and twenty cases of juvenile mild myopia were randomly divided into s...Objective:To observe the clinical effect of traditional Chinese medicine on the prevention and treatment ofjuvenile mild myopia.Methods:One hundred and twenty cases of juvenile mild myopia were randomly divided into six groups,with 20 cases in each group:western medicine group,ultrasonic group,acupuncture group,auricular point group,traditional Chinese oral decoction group,and traditional Chinese medicine comprehensive therapy group.The therapeutic effects of the treatment administered to the six groups were compared.Result:In the post-treatment and follow-up stages,the visual acuity of the traditional Chinese medicine comprehensive therapy group significantly improved along with reduced diopter compared to the other groups(p<0.05).However,the axial length of the six groups had no significant change compared with that before treatment(p>0.05).There were no adverse reactions in any of the patients.Conclusion:In the treatment of juvenile mild myopia,traditional Chinese medicine comprehensive therapy has good therapeutic effect without any adverse reactions;thus,it is worthy of clinical promotion.展开更多
Objective To analyze the complications of laparoscopic cholecystectomy (LC) and their affecting factors and investigate their prevention and treatment. Methods The clinical data of 18 726 patients treated with LC betw...Objective To analyze the complications of laparoscopic cholecystectomy (LC) and their affecting factors and investigate their prevention and treatment. Methods The clinical data of 18 726 patients treated with LC between March 1992 to January 2001 in our hospital were retrospectively analyzed. Results The complications were common bile duct injury in 28 cases (0. 15%), bile leakage in 62 (0. 33% ), introabdominal hemorrhage in 6 (0.03) and postoperative introabdominal abscess in 4 (0. 02). The causes for these complications were improper choice of indications and surgeon’s back of knowledge and experience in identifying the abnormality of bile duct anatomy. Conclusion The major complications of LC are bile duct leakage and injury. The injury can be avoided through careful performance of LC. Immediate discovery and proper treatment will result in good outcome.7 refs.1 fig,2 tabs.展开更多
Objective To analyze the causes and prevention and treatment of cerebrospinal fluid leak during transsphenoidal pituitary adenoma surgery. Methods Retrospective study of 260 cases of microscopic transsphenoidal surger...Objective To analyze the causes and prevention and treatment of cerebrospinal fluid leak during transsphenoidal pituitary adenoma surgery. Methods Retrospective study of 260 cases of microscopic transsphenoidal surgery and 274 cases of endoscopic surgery for resection of the pituitary adenomas was performed. CSF leak occurred展开更多
With the recent advances in detection and treatment of cancer,there is an increasing emphasis on the efficacy and safety aspects of cancer therapy.Radiation therapy is a common treatment for a wide variety of cancers,...With the recent advances in detection and treatment of cancer,there is an increasing emphasis on the efficacy and safety aspects of cancer therapy.Radiation therapy is a common treatment for a wide variety of cancers,either alone or in combination with other treatments.Ionising radiation injury to the gastrointestinal tract is a frequent side effect of radiation therapy and a considerable proportion of patients suffer acute or chronic gastrointestinal symptoms as a result.These side effects often cause morbidity and may in some cases lower the efficacy of radiotherapy treatment.Radiation injury to the gastrointestinal tract can be minimised by either of two strategies:technical strategies which aim to physically shift radiation dose away from the normal intestinal tissues,and biological strategies which aim to modulate the normal tissue response to ionising radiation or to increase its resistance to it.Although considerable improvement in the safety of radiotherapy treatment has been achieved through the use of modern optimised planning and delivery techniques,biological techniques may offer additional further promise.Different agents have been used to prevent or minimize the severity of gastrointestinal injury induced by ionising radiation exposure,including biological,chemical and pharmacological agents.In this review we aim to discuss various technical strategies to prevent gastrointestinal injury during cancer radiotherapy,examine the different therapeutic options for acute and chronic gastrointestinal radiation injury and outline some examples of research directions and considerations for prevention at a pre-clinical level.展开更多
BACKGROUND Post endoscopic retrograde cholangiopancreatography (ERCP) is comparatively complex application. Researchers has been investigated prevention of post-ERCP pancreatitis (PEP), since it has been considered to...BACKGROUND Post endoscopic retrograde cholangiopancreatography (ERCP) is comparatively complex application. Researchers has been investigated prevention of post-ERCP pancreatitis (PEP), since it has been considered to be the most common complication of ERCP. Although ERCP can lead various complications, it can also be avoided. AIM To study the published evidence and systematically review the literature on the prevention and treatment for PEP. METHODS A systematic literature review on the prevention of PEP was conducted using the electronic databases of ISI Web of Science, PubMed and Cochrane Library for relevant articles. The electronic search for the review was performed by using the search terms “Post endoscopic retrograde cholangiopancreatography pancreatitis” AND “prevention” through different criteria. The search was restricted to randomized controlled trials (RCTs) performed between January 2009 and February 2019. Duplicate studies were detected by using EndNote and deleted by the author. PRISMA checklist and flow diagram were adopted for evaluation and reporting. The reference lists of the selected papers were also scanned to find other relevant studies. RESULTS 726 studies meeting the search criteria and 4 relevant articles found in the edited books about ERCP were identified. Duplicates and irrelevant studies were excluded by screening titles and abstracts and assessing full texts. 54 studies were evaluated for full text review. Prevention methods were categorized into three groups as (1) assessment of patient related factors;(2) pharmacoprevention;and (3) procedural techniques for prevention. Most of studies in the literature showed that young age, female gender, absence of chronic pancreatitis, suspected Sphincter of Oddi dysfunction, recurrent pancreatitis and history of previous PEP played a crucial role in posing high risks for PEP. 37 studies designed to assess the impact of 24 different pharmacologic agents to reduce the development of PEP delivered through various administration methods were reviewed. Nonsteroidal anti-inflammatory drugs are widely used to reduce risks for PEP. Rectal administration of indomethacin immediately prior to or after ERCP in all patients is recommended by European Society for Gastrointestinal Endoscopy guidelines to prevent the development of PEP. The majority of the studies reviewed revealed that rectally administered indomethacin had efficacy to prevent PEP. Results of the other studies on the other pharmacological interventions had both controversial and promising results. Thirteen studies conducted to evaluate the efficacy of 4 distinct procedural techniques to prevent the development of PEP were reviewed. Pancreatic Stent Placement has been frequently used in this sense and has potent and promising benefits in the prevention of PEP. Studies on the other procedural techniques have had inconsistent results. CONCLUSION Prevention of PEP involves multifactorial aspects, including assessment of patients with high risk factors for alternative therapeutic and diagnostic techniques, administration of pharmacological agents and procedural techniques with highly precise results in the literature.展开更多
Table of Contents Preamble 1 Prevalence of hypertension in Chinese population 1.1 Prevalence,incidence and epidemic trend of hypertension in Chinese population 1.2 Awareness,treatment and control of Hypertension in Ch...Table of Contents Preamble 1 Prevalence of hypertension in Chinese population 1.1 Prevalence,incidence and epidemic trend of hypertension in Chinese population 1.2 Awareness,treatment and control of Hypertension in China 1.3 Important risk factors for hypertension in Chinese population 2 Hypertension and cardiovascular risk 2.1 Relationship between blood pressure and cardiovascular risk 2.2 Cardiovascular risk characteristics of hypertension population in China 3 Diagnostic evaluation 3.1 Medical history 3.2 Physical examination 3.3 Laboratory examinations 3.4 Genetic analysis 3.5 BP measurement 3.6 Evaluation of target organ damage.展开更多
Traditional Chinese medicine(TCM) has played a positive role in the management of hepatocarcinoma. Hepatocarcinoma patients may present Qi-stagnation, damp-heat, blood stasis, Qi-deficiency, Yin-deficiency and other T...Traditional Chinese medicine(TCM) has played a positive role in the management of hepatocarcinoma. Hepatocarcinoma patients may present Qi-stagnation, damp-heat, blood stasis, Qi-deficiency, Yin-deficiency and other TCM syndromes(Zheng). Modern treatments such as surgery, transarterial chemoembolization(TACE) and high intensity focus ultrasound treatment would influence the manifestation of TCM syndromes. Herbs with traditional efficacy of tonifying Qi, blood and Yin, soothing liver-Qi stagnation, clearing heat and detoxifying and dissolving stasis, have been demonstrated to be potent to prevent hepatocarcinogenesis. TCM has been widely used in all aspects of integrative therapy in hepatocarcinoma, including surgical resection, liver transplantation, TACE, local ablative therapies and even as monotherapy for middle-advanced stage hepatocarcinoma. Clinical practices have confirmed that TCM is effective to alleviate clinical symptoms, improve quality of life and immune function, prevent recurrence and metastasis, delay tumor progression, and prolong survival time in hepatocarcinoma patients. The effective mechanism of TCM against hepatocarcinoma is related to inducing apoptosis, autophagy, anoikis and cell senescence, arresting cell cycle, regulating immune function, inhibiting metastasis and angiogenesis, reversing drug resistance and enhancing effects of chemotherapy. Along with the progress of research in this field, TCM will contribute more to the prevention and treatment of hepatocarcinoma.展开更多
For prevention and treatment of Kaschin-Beck disease by applying Se fertilizer to soil to increase Se up to normal level for the wheat grains is introduced in this paper. After use this measure the intake of Se by the...For prevention and treatment of Kaschin-Beck disease by applying Se fertilizer to soil to increase Se up to normal level for the wheat grains is introduced in this paper. After use this measure the intake of Se by the residents in the exemplary area increased from 10.4μg to 33.6 μg per day in average. After supplementing Se to human body one year, there is no new patient found among 300 healthy children in the exemplary area but 4 patients found among 264 healthy children in the control area. It is shown that by applying Se fertilizer to KBD area is a effective way for preventing and cure this disease.展开更多
文摘Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.
基金National Natural Science Foundation of China(No.82074419)"Double First-Class"Key Research Project of Gansu Provincial Education Department(No.GSSYLxM-05)。
文摘Doxorubicin is an anthracycline antibiotic.As a broad-spectrum antitumor drug,it is widely used in clinic.However,doxorubicin is dose-dependent and shows obvious cardiotoxicity,which limits its clinical application.At present,the mechanism of doxorubicin induced cardiotoxicity has not been fully clarified.Reducing cardiotoxicity and improving the scope of clinical application have become the focus of research in recent years.This paper reviews the mechanism of doxorubicin cardiotoxicity and the prevention and treatment of doxorubicin cardiotoxicity with traditional Chinese medicine,in order to provide reference for the combined application of doxorubicin.
文摘Objective:This paper aims to discuss the prevention and treatment strategies of gastrointestinal diseases in college students.Methods:A sample of 60 college students suffering from gastrointestinal diseases,from August 2021 to August 2022,was used to discuss the symptoms,causes,prevention strategies,and treatment strategies of gastrointestinal diseases based on questionnaire survey.Results:The high-incidence types of gastrointestinal diseases in college students mainly included chronic gastritis,acute gastritis,duodenal ulcer,and dyspepsia,which were closely related to mental state,diet,and living habits.Conclusion:There are many causes of gastrointestinal diseases in college students.During the period of active symptomatic treatment,it is necessary to focus on the prevention of gastrointestinal diseases in colleges and universities,correct the unhealthy lifestyle of students,and reduce the risk of gastrointestinal diseases.
文摘Corona virus disease 2019(COVID-19)infection has become a major public health issue affecting human health.The main goal of epidemic prevention and control at the current stage in China is to“protect people’s health and prevent severe cases”.Patients with lung cancer who receive antitumor therapy have low immunity,and the risk of severe illness and death once infected is much higher than healthy people,so they are vulnerable to COVID-19 infection.At present,less attention has been paid to the prevention and treatment of COVID-19 infection in patients with lung cancer in domestic guidelines and consensus.Based on the published data in China and abroad,we proposed recommendations and formed expert consensus on the vaccination of COVID-19,the use of neutralizing antibodies and small molecule antiviral drugs for patients with lung cancer,for physician’s reference.
文摘Seeds of flax or linseed(Linum usitatissimum L.)are important nutraceutical foods with antioxidant,anti-inflammatory,estrogenic,laxative,and antibacterial properties.Flaxseed oil and seeds are the richest vegetarian source of omega-3 fatty acids.Consumption of flaxseeds helps in prevention and control of cardiovascular disease,neurodegenerative disorders,obesity,diabetes mellitus,polycystic ovary syndrome,gout,liver and kidney dysfunction,oxidative stress-related diseases,post-menopausal symptoms,osteoporosis,irritable bowel syndrome,dry eye disease,cystic fibrosis,diarrhea,and cancer,particularly of the mammary and prostate gland cancer.Of late,flaxseed is gaining more importance not only because of its industrial values but also due to its nutraceutical and pharmaceutical properties.The literature review was performed using PubMed,Scopus,PubMed Central,Google Scholar,and Web of Science from 1995 onwards.Data was also obtained from websites/books/book chapters.
基金supported by the Scientific Research Project of Hebei Provincial Administration of Traditional Chinese Medicine (No.2021175).
文摘Objective:Using big data mining technology and network pharmacology,this study aimed to identify the dominant traditional Chinese medicine(TCM)for the prophylaxis and treatment of severe Corona Virus Disease 2019(COVID-19),predict the pharmacological mechanism of the dominant anti-epidemic TCM,and provide clinical guidance for COVID-19 prevention and control.Methods:The Traditional Chinese Medicine Inheritance Computing Platform V3.0 was utilized to identify the high-frequency TCM in the adult severe prescriptions of the national Diagnosis and Treatment Plan for COVID-19(Trial 10th edition)and the TCM prophylaxis and cure plan for COVID-19 in 27 regions.The active ingredients and potential targets of the high-frequency core drugs were analyzed using Traditional Chinese Medicine Systems Pharmacology Technology Platform,Traditional Chinese Medicine Integrated Database,and Traditional Chinese Medicine Encyclopedia Database,and the network of“core drug active ingredient-potential targets”was obtained.The String platform was used to establish the protein-protein interaction structure chart,and Cytoscape software was used for visualization and network topology analysis to identify pivotal targets.Signal pathway enrichment analysis of the core targets was performed,and the affinity of the active components entering the blood was predicted by docking with the related targets of the novel coronavirus.Results:Ellagic acid,Vestitol,naringin,dehydroglyasperins C,quercetin,and kaemol were identified as 67 active constituents in the blood.After docking the active constituents with angiotensin-converting enzyme II,3C-likeProteinase,and tyrosine protein kinase receptor UFO,they all showed good affinity.The pivotal targets mainly involved inflammatory factors such as IL-6 and TNF.Pathway concentration analysis of gene ontology and Kyoto Encyclopedia of Genes and Genomes pathways focused on inflammatory and immune-related pathways such as the TNF signaling pathway.Conclusion:The high-frequency core drugs may act on the body through active components such as ellagic acid,Vestitol,naringin,dehydroglyasperins C,quercetin,and kaemol.Inflammatory and related immune pathways,such as the TNF signaling pathway,may suppress cytokine storms and effectively treat patients with severe COVID-19.
基金Beijing innovation cultivation research funding project for biomedicine and life science(No.Z151100003915132)The youth project of national natural science foundation(No.81804095)。
文摘Chronic venous insufficiency is characterized by high incidence,difficult treatment and high recurrence rate.Traditional Chinese Medicine Preventive Treatment Theory is one of the important core contents in the theory of TCM.By using the theory of Traditional Chinese Medicine Preventive Treatment,using the theory of“prevention before illness,prevention the disease continues to change and prevention repeated when the disease has been cured”,can reduce the incidence rate effectively,improve the effect of clinical treatment,it is also to enrich and develop the theory of Traditional Chinese Medicine Preventive Treatment.
文摘While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID‑19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the immune function and relieving symptoms in COVID‑19 patients.This article elaborates the long history of Tuina in treating and preventing epidemic diseases and its effect in improving the immune function.It also introduces some special Tuina methods,for instance,sputum drainage by the back‑patting method to enable the discharge of sputum;slant‑scrubbing method applied on the hypochondriac regions to bring the effect of soothing the liver to regulate qi,which may also relieve anxiety of patients with COVID‑19;and spine‑pinching method to enhance human resistance to diseases,which is more suitable for the elderly and for children with mild or common types of COVID‑19 and can also be used for health care and disease prevention among the general population.Tuina methods for children using the common children’s specific Tuina points and manipulations to improve children’s body constitution are also mentioned in the article.Self‑acupoint Tuina for health care,including acupoints for prevention purposes,acupoints for early clinical stage(mild stage)and recovery stage,as well as acupoints for children health care and specific operations,is also illustrated in the article.Moreover,basic exercises for health care,such as eight‑section brocade,Shaolin internal exercises,six‑character formula,and change of tendons,are also presented.In the final analysis,this article is aimed at some ideas and feasible applications of Tuina therapy in the prevention and treatment of COVID‑19,in the hope to provide some worthy experience and introduce methods in preventing and fighting against COVID‑19 to people all over the world.
文摘While traditional Chinese medicine has displayed a positive and effective role in saving lives of COVID-19 patients,Tuina,which is an important component in Chinese medicine,has also shown its merits in enhancing the immune function and relieving symptoms in COVID-19 patients.This article elaborates the long history of Tuina in treating and preventing epidemic diseases and its effect in improving the immune function.It also introduces some special Tuina methods,lor instance,sputum drainage by the back-patting method to enable the discharge of sputum;slant-scrubbing method applied on the hypochondriac regions to bring the effect of soothing the liver to regulate qi,which may also relieve anxiety of patients with COVID-19;and spine-pinching method to enhance human resistance to diseases,which is more suitable for the elderly and for children with mild or common types of COVID-19 and can also be used for health care and disease prevention among the general population.Tuina methods for children using the common childreifs specific Tuina points and manipulations to improve children’s body constitution are also mentioned in the article.Self-acupoint Tuina for health care,including acupoints for prevention purposes,acupoints for early clinical stage(mild stage)and recovery stage,as well as acupoints for children health care and specific operations,is also illustrated in the article.Moreover,basic exercises for health care,such as eight-section brocade,Shaolin internal exercises,six-character formula,and change of tendons,are also presented.In the final analysis,this article is aimed at some ideas and feasible applications of Tuina therapy in the prevention and treatment of COVID-19,in the hope to provide some worthy experience and introduce methods in preventing and fighting against COVID-19 to people all over the world.
文摘Objective:The objective of this study is to investigate the risk factors for the occurrence of lower limb lymphedema in patients with endometrial cancer after surgery and to make recommendations for prevention and treatment.Materials and Methods:We retrospectively reviewed the clinical data of 135 patients with endometrial cancer treated in the Department of Gynecology of the Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine from January 2013 to December 2019 and analyzed the risk factors of lower limb lymphedema in patients with endometrial cancer after surgery using single factor analysis and multi-factor logistic regression analysis.Results:The incidence of postoperative lower limb lymphedema in patients with endometrial cancer was 11.11%.The results of one-way Chi-square test analysis showed that body mass index(BMI),surgical method,number of lymph node dissection,and radiotherapy were related to the occurrence of lower limb lymphedema,and multi-factor logistic analysis showed that BMI(odds ratio[OR]=6.207),number of lymph node dissection(OR=4.223),and radiotherapy(OR=8.081)were the risk factors for lower limb lymphedema after endometrial cancer surgery.Conclusion:Patients with endometrial cancer with BMI≥≥25 kg/m^(2),high number of lymph node dissection,and postoperative radiotherapy are more likely to develop lower limb lymphedema,and they should be given priority attention and timely preventive and curative measures.
基金The 2019 Project of Sichuan Sexual Sociology and Sex Education Research Center(SXJYZ1912)the first batch of doctoral special scientific research funds of Sichuan University of Arts and Sciences(2019BS003R).
文摘Through the painstaking efforts,the situation of epidemic prevention and control is now developing in a positive direction.Nutritional Diet health management is an important part of health management.The main objective of nutritional diet health management is to improve the clinical outcomes,quality of life and cost-effectiveness ratio of patients with COVID-19 through standardized nutritional support,nutritional diet supplement and medical nutritional diet therapy,for the benefit of patients with COVID-19.
基金Chongqing Science and Technology Project of Science and health joint traditional Chinese medicine in 2017(No.ZY201703020)Yanghe decoction combined with minimally invasive percutaneous Catheter Drainage and local chemotherapy for the treatment of abscess of Crista tuberculosis.
文摘Objective:To review the research progress of using Chinese medicine ginseng to prevent and treat AIDS in China.Methods:Based on the method of TCM syndrome differentiation,Chinese medical researchers divided AIDS into four types:heat toxin stagnation type,Qi and blood deficiency type,stasis and internal resistance type,and Qi and Yin injury type.Results:The therapeutic effects of the compound preparation of traditional Chinese medicine were significant,such as Aikang capsule,Tangcao tablet,Wuweilingqi capsule,Aining granule,compound Sanhuang powder,etc.Astragalus,licorice,honeysuckle,Scutellaria,bupleurum,Salvia miltiorrhiza,Viola,Hedyotis diffusa and other 8 kinds of traditional Chinese medicine have been proved to have anti HIV effect.Conclusion:Among the 27 kinds of Chinese medicine ginseng,Andrographis paniculata,Viola,Arnebia,Arctium lappa,Sophora flavescens,honeysuckle,Guanzhong,Prunella,Coptis,Wolfberry,Wedelia and epimedium have been proved to have the effect of preventing HIV replication.
基金Xi'an Hospital of Traditional Chinese Medicine 2019 Hospital Level Scientific Research Project(Project Number:YJ201905)。
文摘Objective:To observe the clinical effect of traditional Chinese medicine on the prevention and treatment ofjuvenile mild myopia.Methods:One hundred and twenty cases of juvenile mild myopia were randomly divided into six groups,with 20 cases in each group:western medicine group,ultrasonic group,acupuncture group,auricular point group,traditional Chinese oral decoction group,and traditional Chinese medicine comprehensive therapy group.The therapeutic effects of the treatment administered to the six groups were compared.Result:In the post-treatment and follow-up stages,the visual acuity of the traditional Chinese medicine comprehensive therapy group significantly improved along with reduced diopter compared to the other groups(p<0.05).However,the axial length of the six groups had no significant change compared with that before treatment(p>0.05).There were no adverse reactions in any of the patients.Conclusion:In the treatment of juvenile mild myopia,traditional Chinese medicine comprehensive therapy has good therapeutic effect without any adverse reactions;thus,it is worthy of clinical promotion.
文摘Objective To analyze the complications of laparoscopic cholecystectomy (LC) and their affecting factors and investigate their prevention and treatment. Methods The clinical data of 18 726 patients treated with LC between March 1992 to January 2001 in our hospital were retrospectively analyzed. Results The complications were common bile duct injury in 28 cases (0. 15%), bile leakage in 62 (0. 33% ), introabdominal hemorrhage in 6 (0.03) and postoperative introabdominal abscess in 4 (0. 02). The causes for these complications were improper choice of indications and surgeon’s back of knowledge and experience in identifying the abnormality of bile duct anatomy. Conclusion The major complications of LC are bile duct leakage and injury. The injury can be avoided through careful performance of LC. Immediate discovery and proper treatment will result in good outcome.7 refs.1 fig,2 tabs.
文摘Objective To analyze the causes and prevention and treatment of cerebrospinal fluid leak during transsphenoidal pituitary adenoma surgery. Methods Retrospective study of 260 cases of microscopic transsphenoidal surgery and 274 cases of endoscopic surgery for resection of the pituitary adenomas was performed. CSF leak occurred
文摘With the recent advances in detection and treatment of cancer,there is an increasing emphasis on the efficacy and safety aspects of cancer therapy.Radiation therapy is a common treatment for a wide variety of cancers,either alone or in combination with other treatments.Ionising radiation injury to the gastrointestinal tract is a frequent side effect of radiation therapy and a considerable proportion of patients suffer acute or chronic gastrointestinal symptoms as a result.These side effects often cause morbidity and may in some cases lower the efficacy of radiotherapy treatment.Radiation injury to the gastrointestinal tract can be minimised by either of two strategies:technical strategies which aim to physically shift radiation dose away from the normal intestinal tissues,and biological strategies which aim to modulate the normal tissue response to ionising radiation or to increase its resistance to it.Although considerable improvement in the safety of radiotherapy treatment has been achieved through the use of modern optimised planning and delivery techniques,biological techniques may offer additional further promise.Different agents have been used to prevent or minimize the severity of gastrointestinal injury induced by ionising radiation exposure,including biological,chemical and pharmacological agents.In this review we aim to discuss various technical strategies to prevent gastrointestinal injury during cancer radiotherapy,examine the different therapeutic options for acute and chronic gastrointestinal radiation injury and outline some examples of research directions and considerations for prevention at a pre-clinical level.
文摘BACKGROUND Post endoscopic retrograde cholangiopancreatography (ERCP) is comparatively complex application. Researchers has been investigated prevention of post-ERCP pancreatitis (PEP), since it has been considered to be the most common complication of ERCP. Although ERCP can lead various complications, it can also be avoided. AIM To study the published evidence and systematically review the literature on the prevention and treatment for PEP. METHODS A systematic literature review on the prevention of PEP was conducted using the electronic databases of ISI Web of Science, PubMed and Cochrane Library for relevant articles. The electronic search for the review was performed by using the search terms “Post endoscopic retrograde cholangiopancreatography pancreatitis” AND “prevention” through different criteria. The search was restricted to randomized controlled trials (RCTs) performed between January 2009 and February 2019. Duplicate studies were detected by using EndNote and deleted by the author. PRISMA checklist and flow diagram were adopted for evaluation and reporting. The reference lists of the selected papers were also scanned to find other relevant studies. RESULTS 726 studies meeting the search criteria and 4 relevant articles found in the edited books about ERCP were identified. Duplicates and irrelevant studies were excluded by screening titles and abstracts and assessing full texts. 54 studies were evaluated for full text review. Prevention methods were categorized into three groups as (1) assessment of patient related factors;(2) pharmacoprevention;and (3) procedural techniques for prevention. Most of studies in the literature showed that young age, female gender, absence of chronic pancreatitis, suspected Sphincter of Oddi dysfunction, recurrent pancreatitis and history of previous PEP played a crucial role in posing high risks for PEP. 37 studies designed to assess the impact of 24 different pharmacologic agents to reduce the development of PEP delivered through various administration methods were reviewed. Nonsteroidal anti-inflammatory drugs are widely used to reduce risks for PEP. Rectal administration of indomethacin immediately prior to or after ERCP in all patients is recommended by European Society for Gastrointestinal Endoscopy guidelines to prevent the development of PEP. The majority of the studies reviewed revealed that rectally administered indomethacin had efficacy to prevent PEP. Results of the other studies on the other pharmacological interventions had both controversial and promising results. Thirteen studies conducted to evaluate the efficacy of 4 distinct procedural techniques to prevent the development of PEP were reviewed. Pancreatic Stent Placement has been frequently used in this sense and has potent and promising benefits in the prevention of PEP. Studies on the other procedural techniques have had inconsistent results. CONCLUSION Prevention of PEP involves multifactorial aspects, including assessment of patients with high risk factors for alternative therapeutic and diagnostic techniques, administration of pharmacological agents and procedural techniques with highly precise results in the literature.
文摘Table of Contents Preamble 1 Prevalence of hypertension in Chinese population 1.1 Prevalence,incidence and epidemic trend of hypertension in Chinese population 1.2 Awareness,treatment and control of Hypertension in China 1.3 Important risk factors for hypertension in Chinese population 2 Hypertension and cardiovascular risk 2.1 Relationship between blood pressure and cardiovascular risk 2.2 Cardiovascular risk characteristics of hypertension population in China 3 Diagnostic evaluation 3.1 Medical history 3.2 Physical examination 3.3 Laboratory examinations 3.4 Genetic analysis 3.5 BP measurement 3.6 Evaluation of target organ damage.
基金National Natural Science Foundation of China,Nos.81273726 and 81473625Three-year Action Program of Shanghai Municipality for Traditional Chinese Medicine,No.ZY3-CCCX-3-3025
文摘Traditional Chinese medicine(TCM) has played a positive role in the management of hepatocarcinoma. Hepatocarcinoma patients may present Qi-stagnation, damp-heat, blood stasis, Qi-deficiency, Yin-deficiency and other TCM syndromes(Zheng). Modern treatments such as surgery, transarterial chemoembolization(TACE) and high intensity focus ultrasound treatment would influence the manifestation of TCM syndromes. Herbs with traditional efficacy of tonifying Qi, blood and Yin, soothing liver-Qi stagnation, clearing heat and detoxifying and dissolving stasis, have been demonstrated to be potent to prevent hepatocarcinogenesis. TCM has been widely used in all aspects of integrative therapy in hepatocarcinoma, including surgical resection, liver transplantation, TACE, local ablative therapies and even as monotherapy for middle-advanced stage hepatocarcinoma. Clinical practices have confirmed that TCM is effective to alleviate clinical symptoms, improve quality of life and immune function, prevent recurrence and metastasis, delay tumor progression, and prolong survival time in hepatocarcinoma patients. The effective mechanism of TCM against hepatocarcinoma is related to inducing apoptosis, autophagy, anoikis and cell senescence, arresting cell cycle, regulating immune function, inhibiting metastasis and angiogenesis, reversing drug resistance and enhancing effects of chemotherapy. Along with the progress of research in this field, TCM will contribute more to the prevention and treatment of hepatocarcinoma.
文摘For prevention and treatment of Kaschin-Beck disease by applying Se fertilizer to soil to increase Se up to normal level for the wheat grains is introduced in this paper. After use this measure the intake of Se by the residents in the exemplary area increased from 10.4μg to 33.6 μg per day in average. After supplementing Se to human body one year, there is no new patient found among 300 healthy children in the exemplary area but 4 patients found among 264 healthy children in the control area. It is shown that by applying Se fertilizer to KBD area is a effective way for preventing and cure this disease.
