Pu-erh tea is one of post fermented tea manufactured through oxidative maturing by microorganisms. We investigated the preventive effects of pu-erh tea extract on oxazolone-induced type IV allergy in male (ICR) mice. ...Pu-erh tea is one of post fermented tea manufactured through oxidative maturing by microorganisms. We investigated the preventive effects of pu-erh tea extract on oxazolone-induced type IV allergy in male (ICR) mice. Oral administration of 50 mg/kg water extract of pu-erh tea leaves resulted in significant preventive effects against mouse type IV allergy. The hydrophilic Theabrownin-like fraction (TBW-ND), with a high molecular weight of approximately 12,000 or higher, was prepared from pu-erh tea leaves by a solvent-extraction method, followed by Diaion HP-20 column chro-matography and dialysis. Oral and percutaneous administrations of TBW-ND at doses of 18.7 mg/kg and 0.037 mg/ear also resulted in significant preventive effects, which included preventing increases in levels of the proinflam-matory cytokine interleukin-12. The anti-allergic ingredients in TBW-ND were predicted to be highly complex compounds containing of polyphenols, polysaccharides and/or proteins. The results suggest pu-erh tea leaves could be a beneficial food for protecting against delayed-type allergy.展开更多
The reduction stripping behavior of Pu(IV)from 30%TBP/OK with hydroxysemicarbazide(HSC)was investigated,and the separation efficiency of HSC and DMHAN-MMH for U/Pu partitioning in Purex process was compared.The result...The reduction stripping behavior of Pu(IV)from 30%TBP/OK with hydroxysemicarbazide(HSC)was investigated,and the separation efficiency of HSC and DMHAN-MMH for U/Pu partitioning in Purex process was compared.The results show that HSC can effectively realize the separation of Pu from U;using mixer-settlers to simulate U/Pu separation in 1B bank of PUREX,from 16-stage counter current extraction experiment(in which6 stages for supplemental extraction,10 stages for stripping)with flow rate ratio(1BF:1BX:1BS)=4:1:1in 1B contactor,good result was achieved that the yields are both more than 99.99%for uranium and Pu,the separation factor of plutonium from uranium(SF4Pu/U)is 2.8×10,and separation factor of uranium from plutonium(SFU/Pu)is 5.9×104.As a stripping reductant,HSC can effectively achieve the separation of Pu from U and the separation effect is nearly the same with DMHAN-MMH,which contributed to replace enough the latter with HSC in the U/Pu separation in Advanced Purex Process Based on Organic Reagent(APOR)process.展开更多
文摘Pu-erh tea is one of post fermented tea manufactured through oxidative maturing by microorganisms. We investigated the preventive effects of pu-erh tea extract on oxazolone-induced type IV allergy in male (ICR) mice. Oral administration of 50 mg/kg water extract of pu-erh tea leaves resulted in significant preventive effects against mouse type IV allergy. The hydrophilic Theabrownin-like fraction (TBW-ND), with a high molecular weight of approximately 12,000 or higher, was prepared from pu-erh tea leaves by a solvent-extraction method, followed by Diaion HP-20 column chro-matography and dialysis. Oral and percutaneous administrations of TBW-ND at doses of 18.7 mg/kg and 0.037 mg/ear also resulted in significant preventive effects, which included preventing increases in levels of the proinflam-matory cytokine interleukin-12. The anti-allergic ingredients in TBW-ND were predicted to be highly complex compounds containing of polyphenols, polysaccharides and/or proteins. The results suggest pu-erh tea leaves could be a beneficial food for protecting against delayed-type allergy.
基金Supported by China National Nuclear Corporation fund(No.61601090401)
文摘The reduction stripping behavior of Pu(IV)from 30%TBP/OK with hydroxysemicarbazide(HSC)was investigated,and the separation efficiency of HSC and DMHAN-MMH for U/Pu partitioning in Purex process was compared.The results show that HSC can effectively realize the separation of Pu from U;using mixer-settlers to simulate U/Pu separation in 1B bank of PUREX,from 16-stage counter current extraction experiment(in which6 stages for supplemental extraction,10 stages for stripping)with flow rate ratio(1BF:1BX:1BS)=4:1:1in 1B contactor,good result was achieved that the yields are both more than 99.99%for uranium and Pu,the separation factor of plutonium from uranium(SF4Pu/U)is 2.8×10,and separation factor of uranium from plutonium(SFU/Pu)is 5.9×104.As a stripping reductant,HSC can effectively achieve the separation of Pu from U and the separation effect is nearly the same with DMHAN-MMH,which contributed to replace enough the latter with HSC in the U/Pu separation in Advanced Purex Process Based on Organic Reagent(APOR)process.
