In August of 2022,I gave the opening keynote address at the 5th North American Congress on Biomechanics,in Ottawa,Canada.The topic of my talk was about whether the research ecosystem was getting a reasonable return on...In August of 2022,I gave the opening keynote address at the 5th North American Congress on Biomechanics,in Ottawa,Canada.The topic of my talk was about whether the research ecosystem was getting a reasonable return on its investment in biomedical research.I provided several examples as to why I posed this question.展开更多
An ADS （automated dispensing system） was implemented in our hospital pharmacy in 2008 to optimize and secure the medication process. The main objective of this study was to compare the projected and the real ROI （r...An ADS （automated dispensing system） was implemented in our hospital pharmacy in 2008 to optimize and secure the medication process. The main objective of this study was to compare the projected and the real ROI （return on investment）, after seven years of use. ROI was calculated annually （from 2008 to 2015）, by deducting the cost of investment （ADS buying and implementation, maintenance, repairs and ADS upgrade） from the cost saving （drugs stock reduction and decrease of pharmacy staff dedicated to global dispensing）. In 2015, total costs saving （＋$1,141,987） were divided between decreasing drug stock value and reduction of pharmacy staff. Total costs of investment （-$978,656） were acquisition, maintenance, repairs and an unplanned upgrade costs. Finally, the real ROI was ＋$163,331 after seven years of use. In 2008, projected ROI was ＋$410,786. The real payback period has been increased by approximately two years （six years of use, instead of four years as expected）. Despite their cost, ADSs are a worthwhile investment, leading to a ROI within a few years. These economic considerations should be put into perspective with optimization of drugs stock management, greater efficiency of the global dispensing process, securitization of medication process and redeployment of pharmacy staff.展开更多
This review article examines the relationship between health and economic development,highlighting the economic benefits of investing in health.The rise of non-communicable diseases(NCDs)and the COVID-19 pandemic have...This review article examines the relationship between health and economic development,highlighting the economic benefits of investing in health.The rise of non-communicable diseases(NCDs)and the COVID-19 pandemic have exposed high demand for increased investment in health as well as critical gaps in the global health system,particularly in low-and middle-income countries,where investments in primary healthcare and innovations in health technologies are lacking.The article emphasizes the importance of examining the economic impact of health,providing a summary of the different pathways through which health impacts the economy and reviewing various economic analyses,including a novel methodology called the health-augmented macroeconomic model(HMM)for evaluating the macroeconomic value of investing in health.The article suggests that reducing disease burdens can effectively generate sizable economic returns,and it is vital to integrate the concept of economic value in health policies and interventions.展开更多
The key aspect to the successful implementation of BOT concept is the raising of finance by project sponsor,so financial engineering techniques and capital structuring skills are required to find the proper mix of deb...The key aspect to the successful implementation of BOT concept is the raising of finance by project sponsor,so financial engineering techniques and capital structuring skills are required to find the proper mix of debt and equity.The capital structure and present a model to determine the equity level from the aspects of financing scale,construction time and return on investment are analyzed.The resulting model can help the sponsor to avoid the capital risk,and offer the government a criterion to evaluate management ability of the sponsor.To show the application and availability of this model,a case study is conducted.Thus,this paper is concern with the determination of financing scale,construction time,and return on investment which would assist the sponsor to ensure that the equity level for optimal capital structure is available prior to the implementation stage in BOT project operation.展开更多
Hongkong’s smooth return creates vast prospect and numerous opportunities for Guangdong-Hongkong economic cooperation. Over the past decade the cooperation has gone a long way, from non-governmental to governmental, ...Hongkong’s smooth return creates vast prospect and numerous opportunities for Guangdong-Hongkong economic cooperation. Over the past decade the cooperation has gone a long way, from non-governmental to governmental, from processing trade to high technology. Presently, it has become a highprofile activity which covers various areas.More than 20,000 representatives from 5,063 corporations participated the symposium. And 1,559 agreements, involving $ 13.159 billion, were signed. Of the investment, $8.7851 billion, or 66.8 per cent is from overseas investors. Of the agreements, 810 or 65 per cent, are high new展开更多
This paper meant to analyze the spatial evolution of a large country in its process of integration with the world economy in general, and, to look into the possible effect of China′s accession into WTO on the future ...This paper meant to analyze the spatial evolution of a large country in its process of integration with the world economy in general, and, to look into the possible effect of China′s accession into WTO on the future development of its spatial economy in particular. Through an approach of increasing returns, external economy, product differentiation and path-dependence, with foreign trade costs incurred by different regions within the large country discriminated, a model of investment and employment flow is developed as a simulation of a large country′s process of integration with the world economy. The modeling indicates that in the process of integration, as there exist differences in foreign trade costs among different regions within the large country, either the spatial economy of the country deviates from its symmetric structure in autarky and falls into a core-periphery relationship, or the effect of industrial agglomeration is reinforced, amplified and locked in, if the agglomeration had been started. The economic gap on either the aggregate or structural basis between different regions within the large country will increase rapidly as the integration proceeds.展开更多
Although widely used, both the Markowitz model and VAR (Value at Risk) model have some limitations in evaluating the risk and return of stock investment. By the analysis of the conceptions of risk and return, together...Although widely used, both the Markowitz model and VAR (Value at Risk) model have some limitations in evaluating the risk and return of stock investment. By the analysis of the conceptions of risk and return, together with the three hypotheses of technological analysis, a novelty model of metering and evaluating the risk and return of stock investment is established. The major indicator of this model , risk-return ratio K, combines the characteristic indicators of risk and return. Regardless of the form of the risk-return probability density functions, this indicator K can always reflect the risk-return performances of the invested stocks clearly and accurately. How to use the model to make optimum investment and how to make portfolio combined with clustering analysis is also explained.展开更多
In order to improve the performance of higher education in the United States, the Goodgrant Foundation intends to donate a total of $100,000,000 (US 100 million) to an appropriate group of schools per year, for five y...In order to improve the performance of higher education in the United States, the Goodgrant Foundation intends to donate a total of $100,000,000 (US 100 million) to an appropriate group of schools per year, for five years, starting in July 2016. For this, our team puts forward upon an optimal investment strategy, which includes the schools to invest, the investment amount of each school, and the return due to investment, to solve this problem. Our main idea is as follows. First of all, we choose suitable investment school universities in the United States. Secondly, we use Analytic Hierarchy Process to get the rate of return on investment and venture capital. Thirdly, we establish a venture capital return model. Finally, solving the mathematical model ensures the investment amount of each school and the return due to investment. To implement this strategy, first of all, we obtain the candidate school based on students score card. Then, according to the factor analysis, we analyze the factors which mainly affect the choice of school. Secondly, we employ Analytic Hierarchy Process to get the rate of return on investment and capital risk. In the end, we establish a risk return model to get investment amount for each school, amount of risk and return. In order to ensure the minimum risk and the maximum return, we set up a multi objective programming model and solve it by using the constraint method. We get the result that includes the maximum net profit of the investment and risk loss rate. According to statistical analysis, we can get the overall return of net income within five years. Finally, we choose 320 candidate schools and get the investment amount of each school according to the principle of as many schools as possible. We have proved that the foundation will receive a return of more than 295.363 million in the next 5 years. After-verification, our strategy can be directly applied to the investment field and get good results.展开更多
文摘In August of 2022,I gave the opening keynote address at the 5th North American Congress on Biomechanics,in Ottawa,Canada.The topic of my talk was about whether the research ecosystem was getting a reasonable return on its investment in biomedical research.I provided several examples as to why I posed this question.
文摘An ADS （automated dispensing system） was implemented in our hospital pharmacy in 2008 to optimize and secure the medication process. The main objective of this study was to compare the projected and the real ROI （return on investment）, after seven years of use. ROI was calculated annually （from 2008 to 2015）, by deducting the cost of investment （ADS buying and implementation, maintenance, repairs and ADS upgrade） from the cost saving （drugs stock reduction and decrease of pharmacy staff dedicated to global dispensing）. In 2015, total costs saving （＋$1,141,987） were divided between decreasing drug stock value and reduction of pharmacy staff. Total costs of investment （-$978,656） were acquisition, maintenance, repairs and an unplanned upgrade costs. Finally, the real ROI was ＋$163,331 after seven years of use. In 2008, projected ROI was ＋$410,786. The real payback period has been increased by approximately two years （six years of use, instead of four years as expected）. Despite their cost, ADSs are a worthwhile investment, leading to a ROI within a few years. These economic considerations should be put into perspective with optimization of drugs stock management, greater efficiency of the global dispensing process, securitization of medication process and redeployment of pharmacy staff.
文摘This review article examines the relationship between health and economic development,highlighting the economic benefits of investing in health.The rise of non-communicable diseases(NCDs)and the COVID-19 pandemic have exposed high demand for increased investment in health as well as critical gaps in the global health system,particularly in low-and middle-income countries,where investments in primary healthcare and innovations in health technologies are lacking.The article emphasizes the importance of examining the economic impact of health,providing a summary of the different pathways through which health impacts the economy and reviewing various economic analyses,including a novel methodology called the health-augmented macroeconomic model(HMM)for evaluating the macroeconomic value of investing in health.The article suggests that reducing disease burdens can effectively generate sizable economic returns,and it is vital to integrate the concept of economic value in health policies and interventions.
文摘The key aspect to the successful implementation of BOT concept is the raising of finance by project sponsor,so financial engineering techniques and capital structuring skills are required to find the proper mix of debt and equity.The capital structure and present a model to determine the equity level from the aspects of financing scale,construction time and return on investment are analyzed.The resulting model can help the sponsor to avoid the capital risk,and offer the government a criterion to evaluate management ability of the sponsor.To show the application and availability of this model,a case study is conducted.Thus,this paper is concern with the determination of financing scale,construction time,and return on investment which would assist the sponsor to ensure that the equity level for optimal capital structure is available prior to the implementation stage in BOT project operation.
文摘Hongkong’s smooth return creates vast prospect and numerous opportunities for Guangdong-Hongkong economic cooperation. Over the past decade the cooperation has gone a long way, from non-governmental to governmental, from processing trade to high technology. Presently, it has become a highprofile activity which covers various areas.More than 20,000 representatives from 5,063 corporations participated the symposium. And 1,559 agreements, involving $ 13.159 billion, were signed. Of the investment, $8.7851 billion, or 66.8 per cent is from overseas investors. Of the agreements, 810 or 65 per cent, are high new
文摘This paper meant to analyze the spatial evolution of a large country in its process of integration with the world economy in general, and, to look into the possible effect of China′s accession into WTO on the future development of its spatial economy in particular. Through an approach of increasing returns, external economy, product differentiation and path-dependence, with foreign trade costs incurred by different regions within the large country discriminated, a model of investment and employment flow is developed as a simulation of a large country′s process of integration with the world economy. The modeling indicates that in the process of integration, as there exist differences in foreign trade costs among different regions within the large country, either the spatial economy of the country deviates from its symmetric structure in autarky and falls into a core-periphery relationship, or the effect of industrial agglomeration is reinforced, amplified and locked in, if the agglomeration had been started. The economic gap on either the aggregate or structural basis between different regions within the large country will increase rapidly as the integration proceeds.
文摘Although widely used, both the Markowitz model and VAR (Value at Risk) model have some limitations in evaluating the risk and return of stock investment. By the analysis of the conceptions of risk and return, together with the three hypotheses of technological analysis, a novelty model of metering and evaluating the risk and return of stock investment is established. The major indicator of this model , risk-return ratio K, combines the characteristic indicators of risk and return. Regardless of the form of the risk-return probability density functions, this indicator K can always reflect the risk-return performances of the invested stocks clearly and accurately. How to use the model to make optimum investment and how to make portfolio combined with clustering analysis is also explained.
文摘In order to improve the performance of higher education in the United States, the Goodgrant Foundation intends to donate a total of $100,000,000 (US 100 million) to an appropriate group of schools per year, for five years, starting in July 2016. For this, our team puts forward upon an optimal investment strategy, which includes the schools to invest, the investment amount of each school, and the return due to investment, to solve this problem. Our main idea is as follows. First of all, we choose suitable investment school universities in the United States. Secondly, we use Analytic Hierarchy Process to get the rate of return on investment and venture capital. Thirdly, we establish a venture capital return model. Finally, solving the mathematical model ensures the investment amount of each school and the return due to investment. To implement this strategy, first of all, we obtain the candidate school based on students score card. Then, according to the factor analysis, we analyze the factors which mainly affect the choice of school. Secondly, we employ Analytic Hierarchy Process to get the rate of return on investment and capital risk. In the end, we establish a risk return model to get investment amount for each school, amount of risk and return. In order to ensure the minimum risk and the maximum return, we set up a multi objective programming model and solve it by using the constraint method. We get the result that includes the maximum net profit of the investment and risk loss rate. According to statistical analysis, we can get the overall return of net income within five years. Finally, we choose 320 candidate schools and get the investment amount of each school according to the principle of as many schools as possible. We have proved that the foundation will receive a return of more than 295.363 million in the next 5 years. After-verification, our strategy can be directly applied to the investment field and get good results.
