Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk...Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk of mortality. Aim: The aim was to identify the associations with absolute values of ΔSBP (|ΔSBP|) ≥10 mm Hg. Subjects and Methods: This study included 2481 patients. Patients with a body mass index ≥25 kg/m<sup>2</sup> were defined as obese. The group of A was defined as following: ankle-brachial index (ABI) was <0.9 or ≥1.3. ΔSBP was expressed as right arm BP minus left arm BP. |ΔSBP| ≥10 mm Hg were analyzed using multivariate logistic analysis. Results: |ΔSBP| ≥10 mm Hg was found in 6.0% of patients and |ΔSBP| < 5 mm Hg in 80.4%. In multivariate analysis, the odds ratios (ORs) of the associations with |ΔSBP| ≥10 mm Hg were significantly associated with abnormal ABI and obesity regardless of sex and age. Moreover, the OR of the combined effects of abnormal ABI and obesity was higher than that of abnormal ABI and obesity alone. Conclusion: |ΔSBP| ≥10 mm Hg was associated with abnormal ABI and obesity. In a primary care setting, blood pressure should be actively measured in both arms. This study suggests that the associations with |ΔSBP| ≥10 mm Hg may be a useful part of screening for abnormal ABI.展开更多
目的:观察8周有氧运动干预对单纯性肥胖患者运动后收缩压恢复(PESBPR)、体成分以及运动能力的影响,并探讨PESBPR与体成分、运动能力的关系。方法:63名肥胖患者随机分为运动组(n=35)和对照组(n=28),运动组进行为期8周的有氧运动,对照组...目的:观察8周有氧运动干预对单纯性肥胖患者运动后收缩压恢复(PESBPR)、体成分以及运动能力的影响,并探讨PESBPR与体成分、运动能力的关系。方法:63名肥胖患者随机分为运动组(n=35)和对照组(n=28),运动组进行为期8周的有氧运动,对照组保持日常生活习惯。实验前、后双能X-线吸收仪(dual-energy X-ray absorptiometry,DXA)测定体成分,包括脂肪重量(fat mass,FM)、去脂体重(fat-free mass,FFM)和体脂百分比(percentage of body fat,BF%);利用症状限制性递增负荷运动实验测试PESBPR和运动能力,PESBPR定义为运动实验后第3min的收缩压与运动后第1min收缩压的比值(即第3min收缩压恢复比,rSBPR),运动能力包括最大耗氧量(VO2max)、最大功率(MP)和力竭时间(ET)。结果:偏相关分析显示,rSBPR与BF%正相关(r=0.412,P<0.01),与VO2max、MP和ET均呈负相关(分别为r=-0.475,P<0.01;r=-0.366,P<0.01;r=-0.308,P<0.01)。8周实验后,运动组体重(P<0.05)、BMI(P<0.05)、FM(P<0.01)、BF%(P<0.01)、安静SBP(P<0.05)、SBPmax(P<0.01)、rSBPR(P<0.05)和PESBPR延迟发生率(P<0.01)降低,VO2max(P<0.05)、最大功率(P<0.05)和力竭时间(P<0.01)升高;对照组各指标均无显著性变化(均为P>0.05)。运动组实验前、后rSBPR变化与BF%变化呈正相关(r=0.315,P<0.01),与VO2max的变化呈负相关(r=-0.338,P<0.01)。结论:1)rSBPR与BF%正相关,与运动能力负相关,rSBPR可能是肥胖患者可调控的心血管危险因素;2)8周有氧运动可显著改善肥胖患者体成分,提高有氧运动能力,下调rSBPR及PESBPR延迟发生率。展开更多
文摘Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk of mortality. Aim: The aim was to identify the associations with absolute values of ΔSBP (|ΔSBP|) ≥10 mm Hg. Subjects and Methods: This study included 2481 patients. Patients with a body mass index ≥25 kg/m<sup>2</sup> were defined as obese. The group of A was defined as following: ankle-brachial index (ABI) was <0.9 or ≥1.3. ΔSBP was expressed as right arm BP minus left arm BP. |ΔSBP| ≥10 mm Hg were analyzed using multivariate logistic analysis. Results: |ΔSBP| ≥10 mm Hg was found in 6.0% of patients and |ΔSBP| < 5 mm Hg in 80.4%. In multivariate analysis, the odds ratios (ORs) of the associations with |ΔSBP| ≥10 mm Hg were significantly associated with abnormal ABI and obesity regardless of sex and age. Moreover, the OR of the combined effects of abnormal ABI and obesity was higher than that of abnormal ABI and obesity alone. Conclusion: |ΔSBP| ≥10 mm Hg was associated with abnormal ABI and obesity. In a primary care setting, blood pressure should be actively measured in both arms. This study suggests that the associations with |ΔSBP| ≥10 mm Hg may be a useful part of screening for abnormal ABI.
文摘目的:观察8周有氧运动干预对单纯性肥胖患者运动后收缩压恢复(PESBPR)、体成分以及运动能力的影响,并探讨PESBPR与体成分、运动能力的关系。方法:63名肥胖患者随机分为运动组(n=35)和对照组(n=28),运动组进行为期8周的有氧运动,对照组保持日常生活习惯。实验前、后双能X-线吸收仪(dual-energy X-ray absorptiometry,DXA)测定体成分,包括脂肪重量(fat mass,FM)、去脂体重(fat-free mass,FFM)和体脂百分比(percentage of body fat,BF%);利用症状限制性递增负荷运动实验测试PESBPR和运动能力,PESBPR定义为运动实验后第3min的收缩压与运动后第1min收缩压的比值(即第3min收缩压恢复比,rSBPR),运动能力包括最大耗氧量(VO2max)、最大功率(MP)和力竭时间(ET)。结果:偏相关分析显示,rSBPR与BF%正相关(r=0.412,P<0.01),与VO2max、MP和ET均呈负相关(分别为r=-0.475,P<0.01;r=-0.366,P<0.01;r=-0.308,P<0.01)。8周实验后,运动组体重(P<0.05)、BMI(P<0.05)、FM(P<0.01)、BF%(P<0.01)、安静SBP(P<0.05)、SBPmax(P<0.01)、rSBPR(P<0.05)和PESBPR延迟发生率(P<0.01)降低,VO2max(P<0.05)、最大功率(P<0.05)和力竭时间(P<0.01)升高;对照组各指标均无显著性变化(均为P>0.05)。运动组实验前、后rSBPR变化与BF%变化呈正相关(r=0.315,P<0.01),与VO2max的变化呈负相关(r=-0.338,P<0.01)。结论:1)rSBPR与BF%正相关,与运动能力负相关,rSBPR可能是肥胖患者可调控的心血管危险因素;2)8周有氧运动可显著改善肥胖患者体成分,提高有氧运动能力,下调rSBPR及PESBPR延迟发生率。
