[Objectives]To examine the effects of Wumen Qingyi Decoction on inflammatory responses in patients with acute pancreatitis(AP).[Methods]Eighty patients with mild or severe AP were randomly allocated to a treatment gro...[Objectives]To examine the effects of Wumen Qingyi Decoction on inflammatory responses in patients with acute pancreatitis(AP).[Methods]Eighty patients with mild or severe AP were randomly allocated to a treatment group(Wumen Qingyi Decoction+baseline treated)or a control group(baseline treated).All patients were managed conservatively.In addition,the Group A received Wumen Qingyi Decoction for 400 mL/d for 7 d.Laboratory parameters,condition of disease and therapeutic effect indexes,and so on,between the two groups were compared.[Results]The recovery of serum levels of amylase(AMS),C reaction protein(CRP),and tumor necrosis factor(TNF-α),interleukin1(IL-1),IL-6,IL-10,as well as the scores of Balthazar and BISAP in Treatment group were quicker than those in Control group(P<0.05).In addition,the improvement of organic dysfunction in Treatment group was better than that in Control group.[Conclusions]The course of combined Wumen Qingyi Decoction and basic treatment of western medicine could effectively adjust the body's inflammatory response to promote the recovery process of acute pancreatitis.展开更多
Objective: To evaluate the short-term therapeutic effects of TCM for IgA nephropathy in children. Methods: Sixty-two children with primary IgA nephropathy diagnosed for the first time by renal biopsy in the authors’ ...Objective: To evaluate the short-term therapeutic effects of TCM for IgA nephropathy in children. Methods: Sixty-two children with primary IgA nephropathy diagnosed for the first time by renal biopsy in the authors’ hospital were randomly divided into a group of 34 cases treated with both TCM and Western medicine and a group of 28 cases treated with Western medicine for six months. The improvements in urinary protein and red blood cell (RBC) were observed and the scores for TCM symptoms and signs were evaluated after 3 months and 6months of treatment. Results: There was no significant difference in the total effective rate between the two groups (χ2=4.743, P>0.05 after treatment for 3 months; and χ2=1.953, P>0.05 after treatment for 6 months). However, the cure plus marked effect rate in the group treated with both TCM and Western medicine was higher than that in the group treated with Western medicine (71.9% vs 45.5%, P<0.05 after treatment for 3 months). At the end of treatment, significant difference were found in the effective rate (9.3% vs 10.5%, χ2=9.653, P<0.01) and in the total score (0.81+1.18 vs 3.42+2.52,t=4.19, P<0.001) between the two groups. Conclusion: Treatment with both TCM and Western medicine can effectively improve the TCM symptoms and signs in child patients with IgA nephropathy, and alleviate hematuria and albuminuria.展开更多
基金Supported by the Science and Technology Project of Suzhou Municipal Health Commission(Special Technical Project for Diagnosis and Treatment of Key Clinical Diseases:LCZX201917)2020 Science and Technology Development Plan Project of Suzhou Science and Technology Bureau(SYSD2020149).
文摘[Objectives]To examine the effects of Wumen Qingyi Decoction on inflammatory responses in patients with acute pancreatitis(AP).[Methods]Eighty patients with mild or severe AP were randomly allocated to a treatment group(Wumen Qingyi Decoction+baseline treated)or a control group(baseline treated).All patients were managed conservatively.In addition,the Group A received Wumen Qingyi Decoction for 400 mL/d for 7 d.Laboratory parameters,condition of disease and therapeutic effect indexes,and so on,between the two groups were compared.[Results]The recovery of serum levels of amylase(AMS),C reaction protein(CRP),and tumor necrosis factor(TNF-α),interleukin1(IL-1),IL-6,IL-10,as well as the scores of Balthazar and BISAP in Treatment group were quicker than those in Control group(P<0.05).In addition,the improvement of organic dysfunction in Treatment group was better than that in Control group.[Conclusions]The course of combined Wumen Qingyi Decoction and basic treatment of western medicine could effectively adjust the body's inflammatory response to promote the recovery process of acute pancreatitis.
基金supported by the Capital Medical Development Fund (Traditional Chinese Medicine Category) (No.SF-2007П07)
文摘Objective: To evaluate the short-term therapeutic effects of TCM for IgA nephropathy in children. Methods: Sixty-two children with primary IgA nephropathy diagnosed for the first time by renal biopsy in the authors’ hospital were randomly divided into a group of 34 cases treated with both TCM and Western medicine and a group of 28 cases treated with Western medicine for six months. The improvements in urinary protein and red blood cell (RBC) were observed and the scores for TCM symptoms and signs were evaluated after 3 months and 6months of treatment. Results: There was no significant difference in the total effective rate between the two groups (χ2=4.743, P>0.05 after treatment for 3 months; and χ2=1.953, P>0.05 after treatment for 6 months). However, the cure plus marked effect rate in the group treated with both TCM and Western medicine was higher than that in the group treated with Western medicine (71.9% vs 45.5%, P<0.05 after treatment for 3 months). At the end of treatment, significant difference were found in the effective rate (9.3% vs 10.5%, χ2=9.653, P<0.01) and in the total score (0.81+1.18 vs 3.42+2.52,t=4.19, P<0.001) between the two groups. Conclusion: Treatment with both TCM and Western medicine can effectively improve the TCM symptoms and signs in child patients with IgA nephropathy, and alleviate hematuria and albuminuria.
