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Gastrointestinal tuberculosis:Diagnostic approaches for this uncommon pathology
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作者 Lottie Brown Michael Colwill Andrew Poullis 《World Journal of Clinical Cases》 SCIE 2024年第23期5283-5287,共5页
A case report entitled“Primary gastroduodenal tuberculosis presenting as gastric outlet obstruction”recently published in the World Journal of Clinical Cases presented a rare cause of gastric outlet obstruction and ... A case report entitled“Primary gastroduodenal tuberculosis presenting as gastric outlet obstruction”recently published in the World Journal of Clinical Cases presented a rare cause of gastric outlet obstruction and highlighted the atypical manner in which gastrointestinal tuberculosis(TB)can present.The literature with regards to this rare pathology is limited to case reports and case series with the largest being published using data from between 2003 and 2013.However,since then the diagnostic tools available have significantly changed with more modern and increasingly accurate tests now available.This editorial reviews the current state of the art with regards to diagnosis in gastrointestinal TB. 展开更多
关键词 Gastrointestinal tuberculosis Diagnostic approach MICROBIOLOGY SEROLOGY Molecular diagnosis Infectious disease
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Enhancing perianal disease management with integrated physical and psychological approaches
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作者 Uchenna E Okpete Haewon Byeon 《World Journal of Clinical Cases》 SCIE 2025年第2期59-63,共5页
This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal disease... This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal diseases.The study sheds light on how illness perception,anxiety,and depression significantly influence recovery outcomes.Hou et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor recovery.The article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for patients.The study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases. 展开更多
关键词 Perianal disease Post-operative recovery ANXIETY DEPRESSION Pain management Emotional well-being Multidisciplinary approach
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Contemporary strategies and approaches for characterizing composition and enhancing biofilm penetration targeting bacterial extracellular polymeric substances
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作者 Lan Lu Yuting Zhao +4 位作者 Mingxing Li Xiaobo Wang Jie Zhu Li Liao Jingya Wang 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第4期506-524,共19页
Extracellular polymeric substances(EPS)constitutes crucial elements within bacterial biofilms,facili-tating accelerated antimicrobial resistance and conferring defense against the host's immune cells.Developing pr... Extracellular polymeric substances(EPS)constitutes crucial elements within bacterial biofilms,facili-tating accelerated antimicrobial resistance and conferring defense against the host's immune cells.Developing precise and effective antibiofilm approaches and strategies,tailored to the specific charac-teristics of EPS composition,can offer valuable insights for the creation of novel antimicrobial drugs.This,in turn,holds the potential to mitigate the alarming issue of bacterial drug resistance.Current analysis of EPS compositions relies heavily on colorimetric approaches with a significant bias,which is likely due to the selection of a standard compound and the cross-interference of various EPS compounds.Considering the pivotal role of EPS in biofilm functionality,it is imperative for EPS research to delve deeper into the analysis of intricate compositions,moving beyond the current focus on polymeric materials.This ne-cessitates a shift from heavy reliance on colorimetric analytic methods to more comprehensive and nuanced analytical approaches.In this study,we have provided a comprehensive summary of existing analytical methods utilized in the characterization of EPS compositions.Additionally,novel strategies aimed at targeting EPS to enhance biofilm penetration were explored,with a specific focus on high-lighting the limitations associated with colorimetric methods.Furthermore,we have outlined the challenges faced in identifying additional components of EPS and propose a prospective research plan to address these challenges.This review has the potential to guide future researchers in the search for novel compounds capable of suppressing EPS,thereby inhibiting biofilm formation.This insight opens up a new avenue for exploration within this research domain. 展开更多
关键词 Analytic strategies and approaches Composition characterization Extracellular polymeric substances(EPS) Promoting biofilm penetration
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Optimizing a Transportation System Using Metaheuristics Approaches (EGD/GA/ACO): A Forest Vehicle Routing Case Study
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作者 Hossein Havaeji Thien-My Dao Tony Wong 《World Journal of Engineering and Technology》 2024年第1期141-157,共17页
The large-scale optimization problem requires some optimization techniques, and the Metaheuristics approach is highly useful for solving difficult optimization problems in practice. The purpose of the research is to o... The large-scale optimization problem requires some optimization techniques, and the Metaheuristics approach is highly useful for solving difficult optimization problems in practice. The purpose of the research is to optimize the transportation system with the help of this approach. We selected forest vehicle routing data as the case study to minimize the total cost and the distance of the forest transportation system. Matlab software helps us find the best solution for this case by applying three algorithms of Metaheuristics: Genetic Algorithm (GA), Ant Colony Optimization (ACO), and Extended Great Deluge (EGD). The results show that GA, compared to ACO and EGD, provides the best solution for the cost and the length of our case study. EGD is the second preferred approach, and ACO offers the last solution. 展开更多
关键词 Metaheuristics Algorithms Transportation Costs Optimization approach Cost Minimisation
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Exploring Ester Prodrugs: A Comprehensive Review of Approaches, Applications, and Methods
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作者 Guangyang Zhou 《Pharmacology & Pharmacy》 2024年第8期269-284,共16页
The review provides an overview of the approaches, applications, and methods for ester prodrugs. Ester prodrugs are pharmacologically inactive compounds in their original form but become active drugs on biotransformat... The review provides an overview of the approaches, applications, and methods for ester prodrugs. Ester prodrugs are pharmacologically inactive compounds in their original form but become active drugs on biotransformation within the body, which offers advantages concerning the solubility, stability, and targeted delivery of the active drug. Several approaches of ester prodrugs have been reviewed in this review, including simple ester prodrugs, amino acid ester prodrugs, sugar ester prodrugs, lipid ester prodrugs, and polymeric ester prodrugs. This review incorporates in vitro and in vivo methods as well as the characterization of physical and chemical properties for ester prodrugs, cell culture systems, enzymatic assays, and animal models—all of these having a very important bearing on the evaluation of stability, bioavailability, and efficacy for ester prodrugs. While the benefits of using ester prodrugs are significant, there are also disadvantages like instability, poor or variable enzymatic hydrolysis, and toxicity from released promoieties or by-products. This review discusses solutions to the various limitations that include enhancing stability with ionizable promoieties and using physiologically-based pharmacokinetic modeling. The review also highlights the application of ester prodrugs in neurological disorders, such as Parkinson’s disease, and the ongoing efforts to address the critical limitations in treatment efficacy. Future prodrug strategies are poised to advance significantly by harnessing diverse transport mechanisms across the blood-brain barrier and integrating nanotechnology. 展开更多
关键词 Ester Prodrugs Solubility BIOAVAILABILITY Stability Ester Prodrug approaches Simple Ester Prodrugs Amino Acid Ester Prodrugs Sugar Ester Prodrugs Lipid Ester Prodrugs Polymeric Ester Prodrugs Esterase-Responsive Nanoparticles Hydrolysis Cancer Treatment Cardiovascular Diseases Neurological Disorders
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Task-based approaches to second language pedagogy and the design of Chinese textbooks at Tertiary Level 被引量:2
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作者 Jianjun Urwin Du Liping 《世界汉语教学》 CSSCI 北大核心 2003年第3期84-98,共15页
近年来 ,以任务为基础的第二语言教学法"task basedapproaches"引起了语言教学科研人员以及课程设计者的广泛兴趣。本文作者认为 ,采用这种教学法 ,对以非中国学生为对象的中文教学来说 ,是大有益处的。这种益处可通过使用以... 近年来 ,以任务为基础的第二语言教学法"task basedapproaches"引起了语言教学科研人员以及课程设计者的广泛兴趣。本文作者认为 ,采用这种教学法 ,对以非中国学生为对象的中文教学来说 ,是大有益处的。这种益处可通过使用以任务为基础编写的教科书来获得。本文首先从理论上对这种教学法做了阐释 ,并根据应用语言学及成人教育学的有关理论论证了这种教学方法的益处 ,然后介绍实用专题的类型 ,并论述了如何使学生能够在学习过程中发现有效地领会所学语言的特点 ,文章还有针对性地评议了两本中文教科书。最后 ,作者论述了在今后一段时期内设计编写中文教科书的方向 。 展开更多
关键词 第二语言教学 任务式教学法 教材 应用语言学 对外汉语教学
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On the Application of Task-based Language Teaching Approach to English Phonetic Teaching 被引量:1
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作者 林璐 《海外英语》 2011年第8X期390-391,共2页
Task-based language teaching approach(TBLTA), which lays stress on "learning by doing", gained increasing popularity in English teaching in recent years. The design of phonetic teaching calls for more emphas... Task-based language teaching approach(TBLTA), which lays stress on "learning by doing", gained increasing popularity in English teaching in recent years. The design of phonetic teaching calls for more emphasis from English educators since it is one of the basic rounds of English teaching. This paper made a trial on the utilization of TBLTA in the English phonetic teaching context and designed a TBLTA model for English phonetic teaching based on discussions about model and merits of TBLTA. 展开更多
关键词 task-based language TEACHING approach(TBLTA) model MERITS ENGLISH PHONETIC TEACHING
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Task-Based Approach in Language Teaching
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作者 王坚 《思想战线》 CSSCI 北大核心 2015年第S1期82-84,共3页
During recent years,some notions about tasks have been considered as the major part of analysis in different teaching approaches and teachers are being more interested in the use of taskbased approach both in foreign ... During recent years,some notions about tasks have been considered as the major part of analysis in different teaching approaches and teachers are being more interested in the use of taskbased approach both in foreign and in second language teaching.The main goal of this article is to introduce and discuss some major principles of task-based language teaching and indicates how teachers can apply them in their curriculum. 展开更多
关键词 TASK task-based approach LANGUAGE TEACHING
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Task-Based Approach在高职英语专业《综合英语》中的应用
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作者 杨建国 钟永发 《四川职业技术学院学报》 2008年第4期84-86,共3页
Task-Based Approach(TBA:任务型教学法)不仅有利于提高学生综合运用英语的能力,而且有助于培养学生的自主学习意识与合作精神.本文介绍了任务型语言教学法运用于高职英语专业《综合英语》教学的实施原则和教学模式.
关键词 task-based Appreach教学法 教学模式 教学改革
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On the Effects of Applying Task-based Approach to Business Oral English Teaching in Higher Vocational College
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作者 张铁英 《海外英语》 2012年第6X期82-83,共2页
A teaching experiment was conducted to investigate the feasibility and effectiveness of applying of Task-based approach(TBA) to business oral English teaching in higher vocational college.Instruments are tests and que... A teaching experiment was conducted to investigate the feasibility and effectiveness of applying of Task-based approach(TBA) to business oral English teaching in higher vocational college.Instruments are tests and questionnaire for the experimental participants.Based on the data analysis,it can be concluded that TBA proves to be more effective especially compared with PPP approach. 展开更多
关键词 task-based approach HIGHER VOCATIONAL COLLEGE busi
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Application of Task-based Approach in English Reading Classes in Senior Middle School
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作者 王雷宏 《海外英语》 2014年第9X期122-125,共4页
The traditional teaching approach is teacher-oriented,giving priority to grammar and lexical usage and neglecting the development of students’linguistic ability.The task-based approach is based on tasks and its promi... The traditional teaching approach is teacher-oriented,giving priority to grammar and lexical usage and neglecting the development of students’linguistic ability.The task-based approach is based on tasks and its prominent feature is"learning by doing and learning by using".By accomplishing tasks in target language,students can obtain linguistic knowledge and improve linguistic ability.This thesis is based on task-based approach,referring to English compulsory textbooks in senior middle school,exploring the application of task-based approach in intensive reading classes and providing case studies. 展开更多
关键词 task-based approach SENIOR ENGLISH TEACHING readin
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Application of Task-based Approach in College English Vocabulary Teaching
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作者 杨娜 《海外英语》 2019年第13期275-277,共3页
With the rapid development of economy and society,more and more people pay attention to English teaching.Vocabulary,the basic unit of language,is regarded as the center of language teaching by many linguists and educa... With the rapid development of economy and society,more and more people pay attention to English teaching.Vocabulary,the basic unit of language,is regarded as the center of language teaching by many linguists and educators.For Chinese students,vocabulary learning is also the most difficult and important problem in language learning.Unlike that in English-speaking countries,there is an absence of a foreign language environment for Chinese students,and most of their vocabulary is derived from classroom learning.Thus it is necessary to find an effective method to deal with vocabulary teaching.It analyzes college English vocabulary teaching,as college students have formed the corresponding language skills with more suitability.For a long time,students develop the habit of memorizing words repeatedly,consuming a lot of time,but the result is not satisfactory.Faced with this phenomenon,this paper analyzes the problems existing in College English vocabulary teaching and explores the reasons of the problems.Then it analyzes the application of task-based approach in college English vocabulary teaching. 展开更多
关键词 task-based approach VOCABULARY teaching COLLEGE English APPLICATION CLASSROOM INSTRUCTION
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Consideration on Vocational Students' Participation in Class:With Special Reference to Task-based Approach and Traditional Method
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作者 董晓霞 《海外英语》 2011年第4X期111-113,共3页
This paper covers an experimental study on vocational students' participation in the class under task-based approach and traditional grammar-translation teaching method.As vocational colleges in China have develop... This paper covers an experimental study on vocational students' participation in the class under task-based approach and traditional grammar-translation teaching method.As vocational colleges in China have developed rapidly,teachers are still exploring and experimenting with different teaching approaches in order to find the suitable one(s).Using the theory of task-based approach,the grammartranslation method,the author conducts an experiment by recording.The following key issue has been addressed and some conclusive results have been made.The paper intends to find an answer to the following question:Under which teaching approach can students participate in the class more actively? Based on the above research work,the following result has been reached:Task-based approach can promote students' mastering of vocabulary and grammar,and students participate in the class more actively.The author would like to share her experiences with others in pedagogical studies of teaching vocational college students English. 展开更多
关键词 task-based approach grammar-translation method students’participation
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Using Task-based Instruction Approach to Make Clear Communication
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作者 吴雪花 Teresa K.Debeacker 李恩亮 《海外英语》 2020年第1期260-261,共2页
Unclear,ambiguous,poor communication is one of the causes of major marine disasters.To foster the students'commu-nicative competence,the task-based instruction theory was applied in the design of English for Speci... Unclear,ambiguous,poor communication is one of the causes of major marine disasters.To foster the students'commu-nicative competence,the task-based instruction theory was applied in the design of English for Specific Purpose(ESP)instruction.This paper explored the procedures in task-based language teaching and applied them in ESP class in a Chinese vocational institute. 展开更多
关键词 COMMUNICATION task-based instruction ESP
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Colon cancer and their targeting approaches through nanocarriers:A review 被引量:1
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作者 Richa Kumari Nitin Sharma +1 位作者 Ritu Karwasra Kushagra Khanna 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2023年第3期104-111,共8页
Colon cancer is the fifth most common type of cancer in the world.Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor.Despite maj... Colon cancer is the fifth most common type of cancer in the world.Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor.Despite major medical improvements,colon cancer is still one of the leading causes of cancer-related mortality globally.One of the main issues of chemotherapy is toxicity related to conventional medicines.The targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other organs.Therefore,these delivery systems required lower doses for high therapeutic value with minimum side effects.The current review focuses on targeting therapeutic substances at the desired site using nanocarriers.Additionally,the diagnostic applications of nanocarriers in colorectal cancer are also discussed. 展开更多
关键词 Colon cancer Targeting approaches Chemotherapies NANOCARRIERS Gold nanoparticles Liposomes
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Towards Innovative Research Approaches to Investigating the Role of Emotional Variables in Promoting Language Teachers’ and Learners’ Mental Health 被引量:3
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作者 Ali Derakhshan Yongliang Wang +1 位作者 Yongxiang Wang José Luis Ortega-Martín 《International Journal of Mental Health Promotion》 2023年第7期823-832,共10页
The adequacy of language education largely depends on the favorable and unfavorable emotions that teachers and students experience throughout the education process.Simply said,emotional factors play a key role in impr... The adequacy of language education largely depends on the favorable and unfavorable emotions that teachers and students experience throughout the education process.Simply said,emotional factors play a key role in improving the quality of language teaching and learning.Furthermore,these emotional factors also promote the well-being of language teachers and learners and place them in a suitable mental condition.In view of the favorable impact of emotional factors on the mental health of language teachers and learners,many educational scholars around the world have studied these factors,their background,and their pedagogical consequences.Nonetheless,the majority of previous studies have employed traditional research methods in assessing these variables and their influences on language teachers’and learners’mental health.Because of the complex and dynamic quality of emotional factors,traditional research approaches often fail to evaluate these factors and their dynamic,non-linear connections with teachers’and learners’mental health and well-being.Accordingly,some novel research approaches are required to measure the dynamicity and complexity of emotional factors in language education settings.To address this call,the current state-of-the-art conceptual article seeks to provide new insights for investigating emotional factors and their potential impact on language teachers’and learners’mental states.This study also intends to offer a comprehensive list of emerging methods that take into account the complex and dynamic nature of emotional variables.Finally,the study outlines the potential implications of this review for educational researchers. 展开更多
关键词 Complexity dynamicity emotional factors mental health WELL-BEING innovative research approaches second and foreign language education
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Application of Task-based Teaching Approach to Business Oral English Teaching 被引量:1
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作者 陈小丽 《海外英语》 2012年第21期83-84,89,共3页
Task-based teaching approach(TBTA) is widely accepted and plays a more important role in foreign language teach ing.This paper is aimed at analyzing specific task design and the application of task-based teaching appr... Task-based teaching approach(TBTA) is widely accepted and plays a more important role in foreign language teach ing.This paper is aimed at analyzing specific task design and the application of task-based teaching approach to business oral Eng lish teaching.It briefly introduces what the task-based teaching approach is and Willis'model for TBTA.Based on this model,it probes deeply into the teaching tasks design and teaching procedures.By applying the task-based teaching approach in business oral English teaching,teachers can assign students various tasks in the class to not only arose students'interest in English but also develop their communicative competence of business English. 展开更多
关键词 task-based TEACHING approach BUSINESS ORAL ENGLISH
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On the Application of Task-based Approach in English Listening Teaching at Middle Schools 被引量:1
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作者 许建平 《海外英语》 2015年第9期23-26,共4页
In order to command a foreign language, it requires a balanced development in listening, speaking, reading and writing,which are four essential skills of language competence. Listening is not only a vital approach to ... In order to command a foreign language, it requires a balanced development in listening, speaking, reading and writing,which are four essential skills of language competence. Listening is not only a vital approach to acquire language, but also an important way to communicate with others in our daily life. The Task-based Approach(TBA) focuses on the specific task, which is the learning motivation. The process of finishing the task is the process of learning. The teaching result is judged by the task performed or not. This research discusses the application of TBA in English Listening Teaching at Middle Schools in order to improve the students listening ability. In the first part, the author introduces the background and significance of the research. In the second part, it states the definition of listening comprehension, the characteristics of listening process, three models of listening processing. In the third part, it introduces the definition of Task, characteristics of task, and the principles of designing a task. Finally, it introduces the Task-based Approach. In the fourth part, discusses the current situation of English teaching at middle school,and the elaboration on the task-based model of English listening teaching. All in all, the research is to make the audience to understand the application of Task-based Approach in English listening teaching at middle schools so as to improve the students' English listening ability. 展开更多
关键词 task-based approach MIDDLE SCHOOL english listening TEACHING LISTENING TEACHING at MIDDLE SCHOOL
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Complication rates after direct anterior vs posterior approach for hip hemiarthroplasty in elderly individuals with femoral neck fractures 被引量:3
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作者 Tatiana Charles Nicolas Bloemers +1 位作者 Bilal Kapanci Marc Jayankura 《World Journal of Orthopedics》 2024年第1期22-29,共8页
BACKGROUND Dislocation rates after hemiarthroplasty reportedly vary from 1%to 17%.This serious complication is associated with increased morbidity and mortality rates.Approaches to this surgery are still debated,with ... BACKGROUND Dislocation rates after hemiarthroplasty reportedly vary from 1%to 17%.This serious complication is associated with increased morbidity and mortality rates.Approaches to this surgery are still debated,with no consensus regarding the superiority of any single approach.AIM To compare early postoperative complications after implementing the direct anterior and posterior approaches(PL)for hip hemiarthroplasty after femoral neck fractures.METHODS This is a comparative,retrospective,single-center cohort study conducted at a university hospital.Between March 2008 and December 2018,273 patients(a total of 280 hips)underwent bipolar hemiarthroplasties(n=280)for displaced femoral neck fractures using either the PL(n=171)or the minimally invasive direct anterior approach(DAA)(n=109).The choice of approach was related to the surgeons’practices;the implant types were similar and unrelated to the approach.Dislocation rates and other complications were reviewed after a minimum followup of 6 mo.RESULTS Both treatment groups had similarly aged patients(mean age:82 years),sex ratios,patient body mass indexes,and patient comorbidities.Surgical data(surgery delay time,operative time,and blood loss volume)did not differ significantly between the groups.The 30 d mortality rate was higher in the PL group(9.9%)than in the DAA group(3.7%),but the difference was not statistically significant(P=0.052).Among the one-month survivors,a significantly higher rate of dislocation was observed in the PL group(14/154;9.1%)than in the DAA group(0/105;0%)(P=0.002).Of the 14 patients with dislocation,8 underwent revision surgery for recurrent instability(posterior group),and one of them had 2 additional procedures due to a deep infection.The rate of other complications(e.g.,perioperative and early postoperative periprosthetic fractures and infection-related complications)did not differ significantly between the groups.CONCLUSION These findings suggest that the DAA to bipolar hemiarthroplasty for patients with femoral neck fractures is associated with a lower dislocation rate(<1%)than the PL. 展开更多
关键词 HEMIARTHROPLASTY Femoral neck fracture Direct anterior approach Posterior approach DISLOCATION MORTALITY
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A FLEXIBLE OBJECTIVE-CONSTRAINT APPROACH AND A NEW ALGORITHM FOR CONSTRUCTING THE PARETO FRONT OF MULTIOBJECTIVE OPTIMIZATION PROBLEMS 被引量:1
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作者 N.HOSEINPOOR M.GHAZNAVI 《Acta Mathematica Scientia》 SCIE CSCD 2024年第2期702-720,共19页
In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized pr... In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems. 展开更多
关键词 multiobjective optimization Pareto front SCALARIZATION objective-constraint approach proper efficient solution
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