To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M mode image...To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M mode images. However it is not a true and independent gold standard. We described a new TDI validation method by using a specially developed left ventricular balloon model mounted in a water bath and constructed using two pear shaped balloons. It was connected to a pulsatile flow pump at 8 stroke volumes (50-85 ml/beat). The displacement and velocity of the balloon walls were recorded simultaneously by video imaging and TDI on a GE Vingmed System Five with a 5 MHz phased array probe at the highest frame rates available. Conventional M mode and 2 D imaging verified that our balloon model mimicked the shape and wall motion of left ventricle. There was a good correlation and agreement between the maximum video excursion of the anterior and posterior walls of the phantom and the results of the temporal integration of digital distance data by TDI (Anterior wall: r =0.97, SEE=0.24 mm, ±s =0.04±0.24 mm; Posterior wall: r =0.95, SEE=0.22 mm, ±s =0.03±0.24 mm). Analysis of the velocity profile by the TDI method showed that the velocity at each measured point was correlated well with the velocity obtained from the video images (Anterior wall: r =0.97, SEE=0.30 mm, ±s =-0.04±0.28 mm; Posterior wall: r =0.97, SEE=0.30 mm, ±s =0.04±0.28 mm). Our balloon model provided a new independent method for the validation of TDI data. This study demonstrated that the present TDI system is reliable for measuring wall motion distance and velocity.展开更多
BACKGROUND Right ventricular(RV)function is frequently overlooked during dilated cardiomyopathy(DCM)evaluation.AIM To evaluate RV function in children with idiopathic DCM using relatively recent echocardiographic moda...BACKGROUND Right ventricular(RV)function is frequently overlooked during dilated cardiomyopathy(DCM)evaluation.AIM To evaluate RV function in children with idiopathic DCM using relatively recent echocardiographic modalities.METHODS We prospectively studied the cardiac function in 50 children with idiopathic DCM and 50 healthy children as a control group,using four-dimensional echocardiography(4-DE),Tissue Doppler Imaging(TDI),and two-dimensional-speckles tracking echocardiography(2-D-STE).RV EF was measured by 4-DE.RESULTS The auto left(LV)ejection fractions(EF)measured by 2-D-STE were significantly lower in the patients'group than in the control.The sphericity index was also significantly lower in children with DCM than in the control.RV EF measured by 4-DE was significantly lower in the patient's group than the control.RV S wave,e´/a'ratio,myocardial performance index(MPI),and tricuspid annular plane systolic excursion(TAPSE)were significantly impaired in children with DCM than in control.Both LV and RV global longitudinal strains(GLS)were significantly reduced in children with DCM than in control.RVGLS was significantly associated with the duration since diagnosis,tricuspid annulus S wave,RV MPI,and TAPSE,but not with the age of the patients,RV EF,or e´/a'ratio.CONCLUSION There was impairment of the RV LGS and other systolic and diastolic parameters in children with DCM.STE and TDI can help to detect the early decline of RV function.展开更多
<span style="white-space:nowrap;font-family:Verdana;"><strong>Background: </strong></span>This study aimed to determine the impact of the percutaneous coronary intervention (PCI)...<span style="white-space:nowrap;font-family:Verdana;"><strong>Background: </strong></span>This study aimed to determine the impact of the percutaneous coronary intervention (PCI) on myocardial function assessed by tissue Doppler echocardiography.<span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Methods:</span></b><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">Conventional two-dimensional echocardiography</span><b> </b><span style="font-family:Verdana;">and</span><i> </i><span style="font-family:Verdana;">Myocardial tissue peak velocities were recorded at the lateral, ant.septal, post.septal, posterior, ant. and inferior angles of the mitral annulus as well as at the lateral tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as well as 1 day and 6 weeks after intervention.</span></span><span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Results:</span></b><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">Fifty consecutive patients with chronic stable angina and </span><span style="font-family:Verdana;">preserved systolic left ventricular function (mean age, 58.3 ± 6.594 years;32 men) undergoing PCI were studied. Conventional echocardiographic revealed no statistically significant difference between pre- and post-PCI (1 day after PCI and 6</span><span style="font-family:Verdana;"> weeks after PCI) as regarding trans-mitral and trans-tricuspid flow velocities except as regarding LVEDD, LVESD and LVEF which showed a significant improvement post-PCI. Compared with pre-interventional values, systolic peak velocity and early diastolic velocities improved at all sites (P ≤ </span></span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;">.05 for each). The most pronounced improvement occurred in the septal area. Similarly, late diastolic velocities improved at all sites (P ≤ </span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;">.05 for each) except at post</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">Wall A’. Also, there was a significant improvement of E’DT & E’/A’ ratio after PCI (P value is significant <0.05 for each) but there was insignificant difference between pre & post PCI for E/E’ (P-value = 0.154). There was a significant improvement in tissue Doppler measures of early, late diastolic function and E’/A’ at the lateral tricuspid annulus after PCI compared with baseline values (P value is significant <0.05) but there was an insignificant change in tissue Doppler measures at the lateral tricuspid annulus of E’DT & E/E’ after PCI (repeated measures ANOVA P-value is >0.05 for each). There were significant reductions in IVRT, IVCT & MPI after PCI (P value is significant <0.05 for each) but there was insignificant change in ET after PCI (P-value = 0.09) at the septal angle of the mitral annulus and the lateral angle of the tricuspid annulus.</span><span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Tissue Doppler parameters of diastolic and systolic function improve early after successful PCI, and this effect persists to 6 weeks after the intervention that emphasizes its value in the improvement of regional and global LV functions and myocardial contractility.</span>展开更多
BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneu...BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneumothorax.AIM To evaluate the quantitative assessment of pleural line movement measured by tissue Doppler imaging(TDI)for pneumothorax diagnosis.METHODS Adult patients(n=45)diagnosed with unilateral pneumothorax were included in this study.Each patient underwent TDI of both lungs.The pneumothorax side and contralateral normal lung side were compared using several indices obtained from TDI:peak pleural line velocity(PV_(max)),peak chest wall tissue velocity(CV_(max)),peak pleural line strain value(PS_(max)),peak chest wall tissue strain value(CSmax),PV_(max)/CV_(max)and PS_(max)/CSmax.The receiver operating characteristic analysis was used to evaluate the performance of these quantitative assessments for pneumothorax diagnosis.RESULTS Various quantitative variables of the pneumothorax side were all lower than that of the non-pneumothorax side and included the PV_(max)(0.36 cm/s vs 0.59 cm/s,P<0.001),PS_(max)(1.14%vs 1.90%,P=0.001),PV_(max)/CV_(max)(1.06 vs 4.93,P<0.001),and PS_(max)/CSmax(0.76 vs 1.74,P<0.001).For the discrimination of pneumothorax,the cut-off values of the PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were calculated as 0.50 cm/s,0.94%,1.96,and 1.12,respectively.Similarly,the sensitivities and specificities of PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were 96%and 62%,47%and 91%,93%and 96%,and 82%and 93%,respectively.The area under the receiver operating characteristic curve were 0.84,0.72,0.99,and 0.91,respectively,for PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax.CONCLUSION Quantification analysis of pleural line movement using TDI is a useful tool for the diagnosis of pneumothorax.展开更多
Background:Extra genetic material in patients with Down syndrome(DS)may affect the function of any organ system.We evaluated cardiac functions using conventional tissue Doppler and two-dimensional speckle tracking ech...Background:Extra genetic material in patients with Down syndrome(DS)may affect the function of any organ system.We evaluated cardiac functions using conventional tissue Doppler and two-dimensional speckle tracking echocardiography in patients with DS in the absence of congenital and acquired heart disease in patients.Methods:A total of 115 patients with DS between 6 and 13 years of age with clinically and anatomically normal heart and 55 healthy children were included in this cross-sectional study.DS was diagnosed by a karyotype test.Patients with mosaic type were not included in this study.Systolic and diastolic functions were evaluated by echocardiography.Results:Pulsed waved Doppler transmitral early/late inflow velocity(E/A),tissue Doppler mitral annular early/late diastolic peak velocity(Ea/Aa),transtricuspid E/A and tricuspid valve annulus Ea/Aa,pulmonary venous Doppler systolic/diastolic(S/D)wave ratio were lower in patients with Down syndrome than in the control group(P=0.04,P=0.001,P<0.05,P<0.001,P<0.001,respectively).Mitral and tricuspid annular Ea were lower in patients with DS(P<0.001).The right and left ventricular myocardial performance indexes were higher in patients with DS than in the controls(P<0.01).They had significantly higher left ventricular mass,ejection fraction,the mitral annular plane systolic excursion values.However,the Down syndrome group compared with the controls had a lower strain values examined by two-dimensional longitudinal speckle-tracking strain echocardiography.Conclusion:These findings suggest conventional tissue Doppler and two-dimensional longitudinal speckletracking strain echocardiography were useful methods of investigating ventricular function and identifying a higher incidence of biventricular dysfunction in patients with Down syndrome compared with the healthy controls.展开更多
文摘To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M mode images. However it is not a true and independent gold standard. We described a new TDI validation method by using a specially developed left ventricular balloon model mounted in a water bath and constructed using two pear shaped balloons. It was connected to a pulsatile flow pump at 8 stroke volumes (50-85 ml/beat). The displacement and velocity of the balloon walls were recorded simultaneously by video imaging and TDI on a GE Vingmed System Five with a 5 MHz phased array probe at the highest frame rates available. Conventional M mode and 2 D imaging verified that our balloon model mimicked the shape and wall motion of left ventricle. There was a good correlation and agreement between the maximum video excursion of the anterior and posterior walls of the phantom and the results of the temporal integration of digital distance data by TDI (Anterior wall: r =0.97, SEE=0.24 mm, ±s =0.04±0.24 mm; Posterior wall: r =0.95, SEE=0.22 mm, ±s =0.03±0.24 mm). Analysis of the velocity profile by the TDI method showed that the velocity at each measured point was correlated well with the velocity obtained from the video images (Anterior wall: r =0.97, SEE=0.30 mm, ±s =-0.04±0.28 mm; Posterior wall: r =0.97, SEE=0.30 mm, ±s =0.04±0.28 mm). Our balloon model provided a new independent method for the validation of TDI data. This study demonstrated that the present TDI system is reliable for measuring wall motion distance and velocity.
文摘BACKGROUND Right ventricular(RV)function is frequently overlooked during dilated cardiomyopathy(DCM)evaluation.AIM To evaluate RV function in children with idiopathic DCM using relatively recent echocardiographic modalities.METHODS We prospectively studied the cardiac function in 50 children with idiopathic DCM and 50 healthy children as a control group,using four-dimensional echocardiography(4-DE),Tissue Doppler Imaging(TDI),and two-dimensional-speckles tracking echocardiography(2-D-STE).RV EF was measured by 4-DE.RESULTS The auto left(LV)ejection fractions(EF)measured by 2-D-STE were significantly lower in the patients'group than in the control.The sphericity index was also significantly lower in children with DCM than in the control.RV EF measured by 4-DE was significantly lower in the patient's group than the control.RV S wave,e´/a'ratio,myocardial performance index(MPI),and tricuspid annular plane systolic excursion(TAPSE)were significantly impaired in children with DCM than in control.Both LV and RV global longitudinal strains(GLS)were significantly reduced in children with DCM than in control.RVGLS was significantly associated with the duration since diagnosis,tricuspid annulus S wave,RV MPI,and TAPSE,but not with the age of the patients,RV EF,or e´/a'ratio.CONCLUSION There was impairment of the RV LGS and other systolic and diastolic parameters in children with DCM.STE and TDI can help to detect the early decline of RV function.
文摘<span style="white-space:nowrap;font-family:Verdana;"><strong>Background: </strong></span>This study aimed to determine the impact of the percutaneous coronary intervention (PCI) on myocardial function assessed by tissue Doppler echocardiography.<span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Methods:</span></b><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">Conventional two-dimensional echocardiography</span><b> </b><span style="font-family:Verdana;">and</span><i> </i><span style="font-family:Verdana;">Myocardial tissue peak velocities were recorded at the lateral, ant.septal, post.septal, posterior, ant. and inferior angles of the mitral annulus as well as at the lateral tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as well as 1 day and 6 weeks after intervention.</span></span><span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Results:</span></b><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">Fifty consecutive patients with chronic stable angina and </span><span style="font-family:Verdana;">preserved systolic left ventricular function (mean age, 58.3 ± 6.594 years;32 men) undergoing PCI were studied. Conventional echocardiographic revealed no statistically significant difference between pre- and post-PCI (1 day after PCI and 6</span><span style="font-family:Verdana;"> weeks after PCI) as regarding trans-mitral and trans-tricuspid flow velocities except as regarding LVEDD, LVESD and LVEF which showed a significant improvement post-PCI. Compared with pre-interventional values, systolic peak velocity and early diastolic velocities improved at all sites (P ≤ </span></span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;">.05 for each). The most pronounced improvement occurred in the septal area. Similarly, late diastolic velocities improved at all sites (P ≤ </span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;">.05 for each) except at post</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">Wall A’. Also, there was a significant improvement of E’DT & E’/A’ ratio after PCI (P value is significant <0.05 for each) but there was insignificant difference between pre & post PCI for E/E’ (P-value = 0.154). There was a significant improvement in tissue Doppler measures of early, late diastolic function and E’/A’ at the lateral tricuspid annulus after PCI compared with baseline values (P value is significant <0.05) but there was an insignificant change in tissue Doppler measures at the lateral tricuspid annulus of E’DT & E/E’ after PCI (repeated measures ANOVA P-value is >0.05 for each). There were significant reductions in IVRT, IVCT & MPI after PCI (P value is significant <0.05 for each) but there was insignificant change in ET after PCI (P-value = 0.09) at the septal angle of the mitral annulus and the lateral angle of the tricuspid annulus.</span><span style="font-family:;" "=""> </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Tissue Doppler parameters of diastolic and systolic function improve early after successful PCI, and this effect persists to 6 weeks after the intervention that emphasizes its value in the improvement of regional and global LV functions and myocardial contractility.</span>
文摘BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneumothorax.AIM To evaluate the quantitative assessment of pleural line movement measured by tissue Doppler imaging(TDI)for pneumothorax diagnosis.METHODS Adult patients(n=45)diagnosed with unilateral pneumothorax were included in this study.Each patient underwent TDI of both lungs.The pneumothorax side and contralateral normal lung side were compared using several indices obtained from TDI:peak pleural line velocity(PV_(max)),peak chest wall tissue velocity(CV_(max)),peak pleural line strain value(PS_(max)),peak chest wall tissue strain value(CSmax),PV_(max)/CV_(max)and PS_(max)/CSmax.The receiver operating characteristic analysis was used to evaluate the performance of these quantitative assessments for pneumothorax diagnosis.RESULTS Various quantitative variables of the pneumothorax side were all lower than that of the non-pneumothorax side and included the PV_(max)(0.36 cm/s vs 0.59 cm/s,P<0.001),PS_(max)(1.14%vs 1.90%,P=0.001),PV_(max)/CV_(max)(1.06 vs 4.93,P<0.001),and PS_(max)/CSmax(0.76 vs 1.74,P<0.001).For the discrimination of pneumothorax,the cut-off values of the PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were calculated as 0.50 cm/s,0.94%,1.96,and 1.12,respectively.Similarly,the sensitivities and specificities of PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were 96%and 62%,47%and 91%,93%and 96%,and 82%and 93%,respectively.The area under the receiver operating characteristic curve were 0.84,0.72,0.99,and 0.91,respectively,for PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax.CONCLUSION Quantification analysis of pleural line movement using TDI is a useful tool for the diagnosis of pneumothorax.
文摘Background:Extra genetic material in patients with Down syndrome(DS)may affect the function of any organ system.We evaluated cardiac functions using conventional tissue Doppler and two-dimensional speckle tracking echocardiography in patients with DS in the absence of congenital and acquired heart disease in patients.Methods:A total of 115 patients with DS between 6 and 13 years of age with clinically and anatomically normal heart and 55 healthy children were included in this cross-sectional study.DS was diagnosed by a karyotype test.Patients with mosaic type were not included in this study.Systolic and diastolic functions were evaluated by echocardiography.Results:Pulsed waved Doppler transmitral early/late inflow velocity(E/A),tissue Doppler mitral annular early/late diastolic peak velocity(Ea/Aa),transtricuspid E/A and tricuspid valve annulus Ea/Aa,pulmonary venous Doppler systolic/diastolic(S/D)wave ratio were lower in patients with Down syndrome than in the control group(P=0.04,P=0.001,P<0.05,P<0.001,P<0.001,respectively).Mitral and tricuspid annular Ea were lower in patients with DS(P<0.001).The right and left ventricular myocardial performance indexes were higher in patients with DS than in the controls(P<0.01).They had significantly higher left ventricular mass,ejection fraction,the mitral annular plane systolic excursion values.However,the Down syndrome group compared with the controls had a lower strain values examined by two-dimensional longitudinal speckle-tracking strain echocardiography.Conclusion:These findings suggest conventional tissue Doppler and two-dimensional longitudinal speckletracking strain echocardiography were useful methods of investigating ventricular function and identifying a higher incidence of biventricular dysfunction in patients with Down syndrome compared with the healthy controls.
