A 3D dynamic core of the non-hydrostatic model GRAPES（Global/Regional Assimilation and Prediction System） is developed on the Yin-Yang grid to address the polar problem and to enhance the computational efficiency. T...A 3D dynamic core of the non-hydrostatic model GRAPES（Global/Regional Assimilation and Prediction System） is developed on the Yin-Yang grid to address the polar problem and to enhance the computational efficiency. Three-dimensional Coriolis forcing is introduced to the new core, and full representation of the Coriolis forcing makes it straightforward to share code between the Yin and Yang subdomains. Similar to that in the original GRAPES model, a semi-implicit semi-Lagrangian scheme is adopted for temporal integration and advection with additional arrangement for cross-boundary transport. Under a non-centered second-order temporal and spatial discretization, the dry nonhydrostatic frame is summarized as the solution of an elliptical problem. The resulting Helmholtz equation is solved with the Generalized Conjugate Residual solver in cooperation with the classic Schwarz method. Even though the coefficients of the equation are quite different from those in the original model, the computational procedure of the new core is just the same. The bi-cubic Lagrangian interpolation serves to provide Dirichlet-type boundary conditions with data transfer between the subdomains. The dry core is evaluated with several benchmark test cases, and all the tests display reasonable numerical stability and computing performance. Persistency of the balanced flow and development of both the mountain-induced Rossby wave and Rossby–Haurwitz wave confirms the appropriate installation of the 3D Coriolis terms in the semi-implicit semi-Lagrangian dynamic core on the Yin-Yang grid.展开更多
AIM To investigated the mechanism of the association between the TBX21 T-1993 C promoter polymorphism and autoimmune hepatitis type 1(AIH-1) development.METHODS In vivo,In vivo,and reporter analyses were performed to ...AIM To investigated the mechanism of the association between the TBX21 T-1993 C promoter polymorphism and autoimmune hepatitis type 1(AIH-1) development.METHODS In vivo,In vivo,and reporter analyses were performed to determine the function of transcription factors binding to the T-1993 C element of the TBX21 promoter in human CD4+ T and B cell lines. Flow cytometry and quantitative real-time PCR were used to analyze T-box transcription factor(T-bet) and interferon-γ(IFN-γ) expressions in CD4+ T cells,B cells and monocytes from the peripheral blood of AIH-1 patients including 5-1993 TC and 15-1993 TT genotype carriers,and healthy controls including 10-1993 TC and 25-1993 TT genotype carriers. Furthermore,a range of biochemical indices was measured simultaneously in the blood of AIH-1 patients.RESULTS TBX21-1993 C allele created a strong Yin-Yang 1(YY1)-binding site and decreased transcriptional activity of TBX21 promoter in human CD4+ T and B cells.Higher levels of T-bet and IFN-γ were detected in the circulating CD4+ T cells and B cells of AIH-1 patients carrying the TBX21-1993 TT genotype compared with the patients carrying the-1993 TC genotype and controls with the-1993 TC genotype. T-bet expression levels of circulating T cells and B cells were positively correlated with AIH-1 disease activity. Knockdown of YY1 with si RNA caused increased expression of T-bet and IFN-γ in peripheral blood mononuclear cells in AIH-1 patients. CONCLUSION The repression of TBX21 expression by high-affinity binding of YY1 to the-1993 C allele may contribute to a decreased development of AIH-1 via suppression of type 1 immunity.展开更多
Cyclic 3’,5’-adenosine monophosphate(cAMP)and cyclic 3’,5’-guanosine monophosphate(cGMP)are considered as potential biomarkers for Yin-Yang disharmony in traditional Chinese medicine.However,phosphodiesterase-medi...Cyclic 3’,5’-adenosine monophosphate(cAMP)and cyclic 3’,5’-guanosine monophosphate(cGMP)are considered as potential biomarkers for Yin-Yang disharmony in traditional Chinese medicine.However,phosphodiesterase-mediated ex vivo degradation of these molecules in biological samples may result in their underestimation.In the present study,a ultra-high performance liquid chromatography-tandem mass spectrometry(UHPLC-MS/MS)method was developed for determination of cAMP and cGMP in rat plasma,with special consideration of their stability ex vivo.Following precipitation of proteins from plasma samples with 0.4 M perchloric acid,the analytes were chromatographed on a Shimadzu Shimpack-XR-ODS II column with 2.5 mM ammonium acetate and methanol in gradient mode.The MS/MS detection was performed using multiple reaction monitoring in the positive electrospray ionization mode.The lower limit of quantification was 0.27 ng/mL for cAMP and 0.37 ng/mL for cGMP.The method was used to determine the plasma cAMP and cGMP levels in normal and Yin deficiency diabetic rats treated with or without Rehmannia glutinosa.The developed method may be useful for evaluating the regulatory effects of Chinese herbal medicine on the levels of cAMP and cGMP in the body.展开更多
A global transport model is proposed in which a multimoment constrained finite volume （MCV） scheme is applied to a Yin-Yang overset grid. The MCV scheme defines 16 degrees of freedom （DOFs） within each element to ...A global transport model is proposed in which a multimoment constrained finite volume （MCV） scheme is applied to a Yin-Yang overset grid. The MCV scheme defines 16 degrees of freedom （DOFs） within each element to build a 2D cubic reconstruction polynomial. The time evolution equations for DOFs are derived from constraint conditions on moments of line-integrated averages （LIA）, point values （PV）, and values of first-order derivatives （DV）. The Yin-Yang grid eliminates polar singularities and results in a quasi-uniform mesh. A limiting projection is designed to remove nonphysical oscillations around discontinuities. Our model was tested against widely used benchmarks; the competitive results reveal that the model is accurate and promising for developing general circulation models.展开更多
The global three-dimensional variational(3D-Var)data assimilation is implemented on a new quasi-uniform overset(Yin-Yang)grid on sphere.As a quasi-uniform spherical grid,it covers the sphere by overlapping two perpend...The global three-dimensional variational(3D-Var)data assimilation is implemented on a new quasi-uniform overset(Yin-Yang)grid on sphere.As a quasi-uniform spherical grid,it covers the sphere by overlapping two perpendicularly oriented grid components which is nothing but low latitude region of the usual latitude-longitude grid.Based on this characteristic of the Yin-Yang grid,it enables us to implement the regional 3D-Var system efficiently and accurately on the Yin or Yang component grid,respectively.The global analysis could update directly from the regional analysis since they have the same configurations like the precondition of eigenvalue decomposition for vertical direction,recursive filtering for horizontal direction,minimization method and observation operator and so on.However,the balance equation and vector wind are needed to be paid more attention on the Yin grid analysis due to its coordinate transformation.How to spread the observation information near the boundary of Yin and Yang grid is a key to the 3D-Var analysis.Extending double the horizontal correlation length distance in the overset boundary of Yin and Yang grid has successfully solved the problem.The results show that the analysis on the Yin-Yang grid is reasonable and similar to the result on the latitude-longitude(LAT-LON)grid.This paper provides a promising strategy for the development of a 3D-Var global system for overset grids.展开更多
Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients ...Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients with cervical vertigo treated in our hospital were selected,and the acupuncture group and the acupuncture group were divided into 60 cases each according to the order of the patients.The two groups of patients were given basic treatment measures.Xia Baizhu Tianma Decoction was treated,and the control group was given Yin and Yang blending acupuncture.The left and right vertebral arteries(LVA),right vertebral arteries(RVA),and basal arteries(BA)were compared before and after treatment in the two groups.,Clinical symptom score,clinical efficacy.Results:after treatment,the Vm values of LVA,RVA,and BA in the acupuncture group were lower than those in the acupuncture group(P<0.05);after treatment,acupuncture The dizziness,neck and shoulder pain,headache,daily life work,psychological and social adaptability scores of the drug group were higher than those of the acupuncture group(P<0.05);after treatment,the cure rate of the acupuncture group was 42.37%,and the effective rate was 37.29%.The efficiency was 16.95%,the inefficiency was 3.39%,the cure rate in the acupuncture group was 26.32%,the marked efficiency was 35.09%,the effective rate was 29.82%,and the ineffective rate was 8.77%.The clinical efficacy of the acupuncture group was better than that of the acupuncture group(P<0.05).Conclusion:Traditional Chinese medicine Yin-yang reconciliation acupuncture combined with Pinellia Baizhu Tianma Decoction is definitely effective in treating patients with cervical vertigo,and it can effectively improve the clinical symptoms and clinical effects of patients.展开更多
The traditional way of thinking about women in ancient Chinese philosophy was grounded on the concepts of Yin and Yang.Yin and Yang are the basic principles of the being,the interrelation and interaction between which...The traditional way of thinking about women in ancient Chinese philosophy was grounded on the concepts of Yin and Yang.Yin and Yang are the basic principles of the being,the interrelation and interaction between which provide the original force for the emergence of all beings in the world.In the traditional family construction,men as Yang master the affairs outside the family,and women as Yin master the affairs inside the family(男主外,女主内),which means that women normally had no voice in the social affairs.Her field was limited inside the family.Furthermore,according to Confucian doctrine“husband guides wife”(夫为妻纲),husband is the decision maker of a family,as a king in a state.The prejudice against woman has persisted to the present.This paper will show that within the Confucian tradition,the ontological principles of Yin and Yang have been abused to a certain degree,and women became the sacrifice of the interpretation with this prejudice.The author will argue in this paper,that the Yin-yang principle itself is very flexible.It contains much richer possibilities of interpretation than that had been interpreted in the Confucian tradition.The author’s argument is that if we recognized that each person is a complete Yin-Yang system,we would understand that every human being is a complete and independent person with both virtues of Yin and Yang.Yin is not a substance which restricts women,neither Yang to men.From this perspective,every woman has the potentiality to reach her universality and individuality.The author’s claim is that in building feminism with the resource of ancient Chinese thought,the concepts of Yin and Yang can be revived and given a new life if we think about them in a functional way.In this framework,Yin and Yang are correlative functions in social and family operation.The properties of Yin and Yang are determined only in each particular affair.People practicing functions are Yin or Yang in temporality.展开更多
Objective:To observe the clinical efficacy of compound of owarming yang,descending turbidity and dredging collaterals in the treatment of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome.Meth...Objective:To observe the clinical efficacy of compound of owarming yang,descending turbidity and dredging collaterals in the treatment of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome.Methods:Seventy-six patients of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome were randomly divided into observation group and control group,thirty-eight cases in each group.The control group was given conventional western medicine treatment,while the observation group took compound of owarming yang,descending turbidity and dredging collaterals orally on the basis of conventional western medicine treatment.The course of treatment covered for one month.Before and after treatment,we observed the scores of traditional Chinese medicine symptoms,indicators of renal function[serum creatinine(Scr),blood urea nitrogen(BUN),microalbuminuria(MALB)],indicators of glucose metabolism[fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),glycosylated hemoglobin(HbAlc)],indicators of hemorheology[plasma viscosity(PV),platelet aggregation rate(PAR),fibrinogen(FIB)],Cystatin-C(Cys-C),C-reactive protein(CRP)in the two groups.Results:After treatment,the clinical effect of the observation group was significantly better than the control group(P<0.05).The scores of traditional Chinese medicine symptoms,indicators of renal function(Scr、BUN、UAER),indicators of glucose metabolism(FPG、2hPG、HbAlc),indicators of hemorheology(PV、PAR、FIB),Cys-C and CRP in the two groups were decreased significantly compared with those before treatment(P<0.05),and the decrease in the observation group was superior to that in the control group(P<0.05).Conclusion:Compound of warming yang,descending turbidity and dredging collaterals has remarkable efficacy in treating of diabetic kidney disease patients with yin-yang deficiency and blood stasis syndrome by alleviating clinical symptoms,glucose metabolism,renal function and microcirculatory disturbance,and the mechanism related to alleviation of microinflammation.展开更多
The writings and artistic works of Antoni Tàpies(2009;2011)mirror the influences of the cosmic vision of the Chinese yin-yang.Signs,numbers,and creative procedures related to this correlative thought prevail in h...The writings and artistic works of Antoni Tàpies(2009;2011)mirror the influences of the cosmic vision of the Chinese yin-yang.Signs,numbers,and creative procedures related to this correlative thought prevail in his art.Tàpies integrated different iconological codes from the ancient Chinese thinking into his art to question the existential meaning of the universe and to express his thoughts on the cultural and socio-political controversies of his time.In other words,the images,media,and techniques that he utilized for his works were extensions of his life experiences intertwined with various socio-historical facts and his personal feelings.展开更多
This paper introduces creativity,one of the significant features in maths.The creative mathematical beauty of symmetry and asymmetry are worth investigating in the practicing of Taichi.Symmetrical variances make the r...This paper introduces creativity,one of the significant features in maths.The creative mathematical beauty of symmetry and asymmetry are worth investigating in the practicing of Taichi.Symmetrical variances make the real world.Symmetry can be regarded as a kind of mirroring,like the line symmetry,the mirror image of the other parts,or rotational symmetry.Such characteristics can be vividly demonstrated in the traditional Chinese philosophical yin-yang theory(YY).The accompanying of male and female reveals the friendly cooperative relationship.YY reflects the counterparts of vacancy and firm,inhale and exhale,noun and verb,theory and practice,light and heavy,slow and fast,the pace,the sound effect in the classroom.Such an analysis is undergone about yin and yang in Yi School and Dao De Ching(DDC).Furthermore,there are detailed arguments of the symmetric nature of every verse of DDC,revealing the cultural value of the language.Their applications in the class admit the recognition under the new liberal arts project by China’s Ministry of Education.Yet,the integration of research and teaching is required to go further.展开更多
A Lovely Place(2019)is a collection of the Norwegian writer Kjell Askildsen’s short stories that is translated from German into Chinese by Yang Zhizi.It contains 18 short stories,whose male characters are mainly anal...A Lovely Place(2019)is a collection of the Norwegian writer Kjell Askildsen’s short stories that is translated from German into Chinese by Yang Zhizi.It contains 18 short stories,whose male characters are mainly analyzed by researchers.The paper argues that female characters are playing an indispensable role in compensating the males’life stories and enlightening their worldviews according to Chinese Yin-Yang theory.The females can be classified into the following three groups in terms of their important relations to the males.Firstly,the female is the male’s companion in a certain part of the latter’s life.Secondly,the female facilitates the male’s intellectual growth either spontaneously or purposefully.Thirdly,the female struggles for independence to set an example for the male.The female characters in A Lovely Place present such femininity as beauty,energy,nostalgia,sentimentality,motherhood,etc.,stimulate the males to reflect on their own identities and fulfill their muscularity,and function as the genuine protagonists in the collection as far as the gender relations are concerned.展开更多
Understanding the in vivo transport process provides guidelines for designing ideal nanoparticles(NPs)with higher efficacy and fewer off-target effects.Many factors,such as particle size,morphology,surface potential,s...Understanding the in vivo transport process provides guidelines for designing ideal nanoparticles(NPs)with higher efficacy and fewer off-target effects.Many factors,such as particle size,morphology,surface potential,structural stability,and etc.,may influence the delivering process of NPs due to the existence of various physiological barriers within the body.Herein,we summarise the distinct influences of NP physicochemical properties on the four consecutive in vivo transport steps:(1)navigating with bloodstream within blood vessels,(2)transport across vasculature walls into tumour tissues,(3)intratumoural transport through the interstitial space,and(4)cellular uptake&intracellular delivery by cancerous cells.We found that the philosophy behind the current consensus for NP design has certain similarities to the“Yin-Yang”theory in traditional Chinese culture.Almost all physicochemical properties,regardless of big or small sizes,long or short length,positive or negative zeta potentials,are double-edged swords.The balance of potential benefits and side effects,drug selectivity and accessibility should be fully considered when optimising particle design,similar to the“Yin-Yang harmony”.This paper presents a comprehensive review of the advancements in NPs research,focusing on their distinct features in tumour targeting,drug delivery,and cell uptake.Additionally,it deliberates on future developmental trends and potential obstacles,thereby aiming to uncover the ways these characteristics influence the NPs’biological activity and provide theoretical guidance for the targeted delivery of NPs.展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 41175095)the National Key Technology R&D Program(Grant No. 2012BAC22B01)a research project of the Chinese Academy of Meteorological Sciences (Grant No. 2014Z001)
文摘A 3D dynamic core of the non-hydrostatic model GRAPES（Global/Regional Assimilation and Prediction System） is developed on the Yin-Yang grid to address the polar problem and to enhance the computational efficiency. Three-dimensional Coriolis forcing is introduced to the new core, and full representation of the Coriolis forcing makes it straightforward to share code between the Yin and Yang subdomains. Similar to that in the original GRAPES model, a semi-implicit semi-Lagrangian scheme is adopted for temporal integration and advection with additional arrangement for cross-boundary transport. Under a non-centered second-order temporal and spatial discretization, the dry nonhydrostatic frame is summarized as the solution of an elliptical problem. The resulting Helmholtz equation is solved with the Generalized Conjugate Residual solver in cooperation with the classic Schwarz method. Even though the coefficients of the equation are quite different from those in the original model, the computational procedure of the new core is just the same. The bi-cubic Lagrangian interpolation serves to provide Dirichlet-type boundary conditions with data transfer between the subdomains. The dry core is evaluated with several benchmark test cases, and all the tests display reasonable numerical stability and computing performance. Persistency of the balanced flow and development of both the mountain-induced Rossby wave and Rossby–Haurwitz wave confirms the appropriate installation of the 3D Coriolis terms in the semi-implicit semi-Lagrangian dynamic core on the Yin-Yang grid.
基金Supported by National Natural Science Foundation of China,No.30972595
文摘AIM To investigated the mechanism of the association between the TBX21 T-1993 C promoter polymorphism and autoimmune hepatitis type 1(AIH-1) development.METHODS In vivo,In vivo,and reporter analyses were performed to determine the function of transcription factors binding to the T-1993 C element of the TBX21 promoter in human CD4+ T and B cell lines. Flow cytometry and quantitative real-time PCR were used to analyze T-box transcription factor(T-bet) and interferon-γ(IFN-γ) expressions in CD4+ T cells,B cells and monocytes from the peripheral blood of AIH-1 patients including 5-1993 TC and 15-1993 TT genotype carriers,and healthy controls including 10-1993 TC and 25-1993 TT genotype carriers. Furthermore,a range of biochemical indices was measured simultaneously in the blood of AIH-1 patients.RESULTS TBX21-1993 C allele created a strong Yin-Yang 1(YY1)-binding site and decreased transcriptional activity of TBX21 promoter in human CD4+ T and B cells.Higher levels of T-bet and IFN-γ were detected in the circulating CD4+ T cells and B cells of AIH-1 patients carrying the TBX21-1993 TT genotype compared with the patients carrying the-1993 TC genotype and controls with the-1993 TC genotype. T-bet expression levels of circulating T cells and B cells were positively correlated with AIH-1 disease activity. Knockdown of YY1 with si RNA caused increased expression of T-bet and IFN-γ in peripheral blood mononuclear cells in AIH-1 patients. CONCLUSION The repression of TBX21 expression by high-affinity binding of YY1 to the-1993 C allele may contribute to a decreased development of AIH-1 via suppression of type 1 immunity.
基金financially supported by the National Natural Science Foundation of China(No.J1103606)。
文摘Cyclic 3’,5’-adenosine monophosphate(cAMP)and cyclic 3’,5’-guanosine monophosphate(cGMP)are considered as potential biomarkers for Yin-Yang disharmony in traditional Chinese medicine.However,phosphodiesterase-mediated ex vivo degradation of these molecules in biological samples may result in their underestimation.In the present study,a ultra-high performance liquid chromatography-tandem mass spectrometry(UHPLC-MS/MS)method was developed for determination of cAMP and cGMP in rat plasma,with special consideration of their stability ex vivo.Following precipitation of proteins from plasma samples with 0.4 M perchloric acid,the analytes were chromatographed on a Shimadzu Shimpack-XR-ODS II column with 2.5 mM ammonium acetate and methanol in gradient mode.The MS/MS detection was performed using multiple reaction monitoring in the positive electrospray ionization mode.The lower limit of quantification was 0.27 ng/mL for cAMP and 0.37 ng/mL for cGMP.The method was used to determine the plasma cAMP and cGMP levels in normal and Yin deficiency diabetic rats treated with or without Rehmannia glutinosa.The developed method may be useful for evaluating the regulatory effects of Chinese herbal medicine on the levels of cAMP and cGMP in the body.
基金supported by National Key Technology R&D Program of China (Grant No. 2012BAC22B01)Natural Science Foundation of China (Grant Nos. 10902116, 40805045, and 41175095)Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science (Grant No. 24560187)
文摘A global transport model is proposed in which a multimoment constrained finite volume （MCV） scheme is applied to a Yin-Yang overset grid. The MCV scheme defines 16 degrees of freedom （DOFs） within each element to build a 2D cubic reconstruction polynomial. The time evolution equations for DOFs are derived from constraint conditions on moments of line-integrated averages （LIA）, point values （PV）, and values of first-order derivatives （DV）. The Yin-Yang grid eliminates polar singularities and results in a quasi-uniform mesh. A limiting projection is designed to remove nonphysical oscillations around discontinuities. Our model was tested against widely used benchmarks; the competitive results reveal that the model is accurate and promising for developing general circulation models.
基金National Key R&D Program of China(2017YFC1501901,2017YFA0603901)。
文摘The global three-dimensional variational(3D-Var)data assimilation is implemented on a new quasi-uniform overset(Yin-Yang)grid on sphere.As a quasi-uniform spherical grid,it covers the sphere by overlapping two perpendicularly oriented grid components which is nothing but low latitude region of the usual latitude-longitude grid.Based on this characteristic of the Yin-Yang grid,it enables us to implement the regional 3D-Var system efficiently and accurately on the Yin or Yang component grid,respectively.The global analysis could update directly from the regional analysis since they have the same configurations like the precondition of eigenvalue decomposition for vertical direction,recursive filtering for horizontal direction,minimization method and observation operator and so on.However,the balance equation and vector wind are needed to be paid more attention on the Yin grid analysis due to its coordinate transformation.How to spread the observation information near the boundary of Yin and Yang grid is a key to the 3D-Var analysis.Extending double the horizontal correlation length distance in the overset boundary of Yin and Yang grid has successfully solved the problem.The results show that the analysis on the Yin-Yang grid is reasonable and similar to the result on the latitude-longitude(LAT-LON)grid.This paper provides a promising strategy for the development of a 3D-Var global system for overset grids.
基金2019 Hainan provincial health industry research project(No.178)
文摘Objective:To explore the clinical effect of Yin-yang blending acupuncture with traditional Chinese medicine combined with Banxia Baizhu Tianma Decoction in treating patients with cervical vertigo.Methods:120 patients with cervical vertigo treated in our hospital were selected,and the acupuncture group and the acupuncture group were divided into 60 cases each according to the order of the patients.The two groups of patients were given basic treatment measures.Xia Baizhu Tianma Decoction was treated,and the control group was given Yin and Yang blending acupuncture.The left and right vertebral arteries(LVA),right vertebral arteries(RVA),and basal arteries(BA)were compared before and after treatment in the two groups.,Clinical symptom score,clinical efficacy.Results:after treatment,the Vm values of LVA,RVA,and BA in the acupuncture group were lower than those in the acupuncture group(P<0.05);after treatment,acupuncture The dizziness,neck and shoulder pain,headache,daily life work,psychological and social adaptability scores of the drug group were higher than those of the acupuncture group(P<0.05);after treatment,the cure rate of the acupuncture group was 42.37%,and the effective rate was 37.29%.The efficiency was 16.95%,the inefficiency was 3.39%,the cure rate in the acupuncture group was 26.32%,the marked efficiency was 35.09%,the effective rate was 29.82%,and the ineffective rate was 8.77%.The clinical efficacy of the acupuncture group was better than that of the acupuncture group(P<0.05).Conclusion:Traditional Chinese medicine Yin-yang reconciliation acupuncture combined with Pinellia Baizhu Tianma Decoction is definitely effective in treating patients with cervical vertigo,and it can effectively improve the clinical symptoms and clinical effects of patients.
文摘The traditional way of thinking about women in ancient Chinese philosophy was grounded on the concepts of Yin and Yang.Yin and Yang are the basic principles of the being,the interrelation and interaction between which provide the original force for the emergence of all beings in the world.In the traditional family construction,men as Yang master the affairs outside the family,and women as Yin master the affairs inside the family(男主外,女主内),which means that women normally had no voice in the social affairs.Her field was limited inside the family.Furthermore,according to Confucian doctrine“husband guides wife”(夫为妻纲),husband is the decision maker of a family,as a king in a state.The prejudice against woman has persisted to the present.This paper will show that within the Confucian tradition,the ontological principles of Yin and Yang have been abused to a certain degree,and women became the sacrifice of the interpretation with this prejudice.The author will argue in this paper,that the Yin-yang principle itself is very flexible.It contains much richer possibilities of interpretation than that had been interpreted in the Confucian tradition.The author’s argument is that if we recognized that each person is a complete Yin-Yang system,we would understand that every human being is a complete and independent person with both virtues of Yin and Yang.Yin is not a substance which restricts women,neither Yang to men.From this perspective,every woman has the potentiality to reach her universality and individuality.The author’s claim is that in building feminism with the resource of ancient Chinese thought,the concepts of Yin and Yang can be revived and given a new life if we think about them in a functional way.In this framework,Yin and Yang are correlative functions in social and family operation.The properties of Yin and Yang are determined only in each particular affair.People practicing functions are Yin or Yang in temporality.
基金Key R&D Project of Liaoning Provincial Science and Technology Department(No.2018225042)
文摘Objective:To observe the clinical efficacy of compound of owarming yang,descending turbidity and dredging collaterals in the treatment of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome.Methods:Seventy-six patients of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome were randomly divided into observation group and control group,thirty-eight cases in each group.The control group was given conventional western medicine treatment,while the observation group took compound of owarming yang,descending turbidity and dredging collaterals orally on the basis of conventional western medicine treatment.The course of treatment covered for one month.Before and after treatment,we observed the scores of traditional Chinese medicine symptoms,indicators of renal function[serum creatinine(Scr),blood urea nitrogen(BUN),microalbuminuria(MALB)],indicators of glucose metabolism[fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),glycosylated hemoglobin(HbAlc)],indicators of hemorheology[plasma viscosity(PV),platelet aggregation rate(PAR),fibrinogen(FIB)],Cystatin-C(Cys-C),C-reactive protein(CRP)in the two groups.Results:After treatment,the clinical effect of the observation group was significantly better than the control group(P<0.05).The scores of traditional Chinese medicine symptoms,indicators of renal function(Scr、BUN、UAER),indicators of glucose metabolism(FPG、2hPG、HbAlc),indicators of hemorheology(PV、PAR、FIB),Cys-C and CRP in the two groups were decreased significantly compared with those before treatment(P<0.05),and the decrease in the observation group was superior to that in the control group(P<0.05).Conclusion:Compound of warming yang,descending turbidity and dredging collaterals has remarkable efficacy in treating of diabetic kidney disease patients with yin-yang deficiency and blood stasis syndrome by alleviating clinical symptoms,glucose metabolism,renal function and microcirculatory disturbance,and the mechanism related to alleviation of microinflammation.
文摘The writings and artistic works of Antoni Tàpies(2009;2011)mirror the influences of the cosmic vision of the Chinese yin-yang.Signs,numbers,and creative procedures related to this correlative thought prevail in his art.Tàpies integrated different iconological codes from the ancient Chinese thinking into his art to question the existential meaning of the universe and to express his thoughts on the cultural and socio-political controversies of his time.In other words,the images,media,and techniques that he utilized for his works were extensions of his life experiences intertwined with various socio-historical facts and his personal feelings.
文摘This paper introduces creativity,one of the significant features in maths.The creative mathematical beauty of symmetry and asymmetry are worth investigating in the practicing of Taichi.Symmetrical variances make the real world.Symmetry can be regarded as a kind of mirroring,like the line symmetry,the mirror image of the other parts,or rotational symmetry.Such characteristics can be vividly demonstrated in the traditional Chinese philosophical yin-yang theory(YY).The accompanying of male and female reveals the friendly cooperative relationship.YY reflects the counterparts of vacancy and firm,inhale and exhale,noun and verb,theory and practice,light and heavy,slow and fast,the pace,the sound effect in the classroom.Such an analysis is undergone about yin and yang in Yi School and Dao De Ching(DDC).Furthermore,there are detailed arguments of the symmetric nature of every verse of DDC,revealing the cultural value of the language.Their applications in the class admit the recognition under the new liberal arts project by China’s Ministry of Education.Yet,the integration of research and teaching is required to go further.
文摘A Lovely Place(2019)is a collection of the Norwegian writer Kjell Askildsen’s short stories that is translated from German into Chinese by Yang Zhizi.It contains 18 short stories,whose male characters are mainly analyzed by researchers.The paper argues that female characters are playing an indispensable role in compensating the males’life stories and enlightening their worldviews according to Chinese Yin-Yang theory.The females can be classified into the following three groups in terms of their important relations to the males.Firstly,the female is the male’s companion in a certain part of the latter’s life.Secondly,the female facilitates the male’s intellectual growth either spontaneously or purposefully.Thirdly,the female struggles for independence to set an example for the male.The female characters in A Lovely Place present such femininity as beauty,energy,nostalgia,sentimentality,motherhood,etc.,stimulate the males to reflect on their own identities and fulfill their muscularity,and function as the genuine protagonists in the collection as far as the gender relations are concerned.
基金supported by the Natural Science Foundation of Shanghai(No.21ZR1422800)“One Belt One Road”International Cooperation Project of Shanghai Municipal Committee of Science and Technology(No.19410740900).
文摘Understanding the in vivo transport process provides guidelines for designing ideal nanoparticles(NPs)with higher efficacy and fewer off-target effects.Many factors,such as particle size,morphology,surface potential,structural stability,and etc.,may influence the delivering process of NPs due to the existence of various physiological barriers within the body.Herein,we summarise the distinct influences of NP physicochemical properties on the four consecutive in vivo transport steps:(1)navigating with bloodstream within blood vessels,(2)transport across vasculature walls into tumour tissues,(3)intratumoural transport through the interstitial space,and(4)cellular uptake&intracellular delivery by cancerous cells.We found that the philosophy behind the current consensus for NP design has certain similarities to the“Yin-Yang”theory in traditional Chinese culture.Almost all physicochemical properties,regardless of big or small sizes,long or short length,positive or negative zeta potentials,are double-edged swords.The balance of potential benefits and side effects,drug selectivity and accessibility should be fully considered when optimising particle design,similar to the“Yin-Yang harmony”.This paper presents a comprehensive review of the advancements in NPs research,focusing on their distinct features in tumour targeting,drug delivery,and cell uptake.Additionally,it deliberates on future developmental trends and potential obstacles,thereby aiming to uncover the ways these characteristics influence the NPs’biological activity and provide theoretical guidance for the targeted delivery of NPs.
