期刊文献+
共找到443篇文章
< 1 2 23 >
每页显示 20 50 100
雄安新区记录到一例白变白骨顶
1
作者 路振广 李佳嵘 +1 位作者 潘鹏 侯建华 《野生动物学报》 北大核心 2024年第1期214-215,共2页
2023年3月28日在雄安新区小白洋淀淀区(38.840°N,115.966°E;海拔7 m)调查时记录到1只羽色畸变(colour aberration)的白骨顶(Fulica atra)个体,该个体与正常白骨顶混群,体型相似,头部亦具白色额甲,但颈部以下及背部大部分羽毛... 2023年3月28日在雄安新区小白洋淀淀区(38.840°N,115.966°E;海拔7 m)调查时记录到1只羽色畸变(colour aberration)的白骨顶(Fulica atra)个体,该个体与正常白骨顶混群,体型相似,头部亦具白色额甲,但颈部以下及背部大部分羽毛变白,呈黑白斑状分布,鉴定为白骨顶白变(leucism)个体(图1)。 展开更多
关键词 雄安新区 白骨顶 ABERRATION
下载PDF
FUT8-mediated aberrant N-glycosylation of SEMA7A promotes head and neck squamous cell carcinoma progression
2
作者 Zhonglong Liu Xiaoyan Meng +5 位作者 Yuxin Zhang Jingjing Sun Xiao Tang Zhiyuan Zhang Liu Liu Yue He 《International Journal of Oral Science》 SCIE CAS CSCD 2024年第2期333-348,共16页
SEMA7A belongs to the Semaphorin family and is involved in the oncogenesis and tumor progression.Aberrant glycosylation has been intricately linked with immune escape and tumor growth.SEMA7A is a highly glycosylated p... SEMA7A belongs to the Semaphorin family and is involved in the oncogenesis and tumor progression.Aberrant glycosylation has been intricately linked with immune escape and tumor growth.SEMA7A is a highly glycosylated protein with five glycosylated sites.The underlying mechanisms of SEMA7A glycosylation and its contribution to immunosuppression and tumorigenesis are unclear.Here,we identify overexpression and aberrant N-glycosylation of SEMA7A in head and neck squamous cell carcinoma,and elucidate fucosyltransferase FUT8 catalyzes aberrant core fucosylation in SEMA7A at N-linked oligosaccharides(Asn 105,157,258,330,and 602)via a direct protein‒protein interaction.A glycosylated statue of SEMA7A is necessary for its intra-cellular trafficking from the cytoplasm to the cytomembrane.Cytokine EGF triggers SEMA7A N-glycosylation through increasing the binding affinity of SEMA7A toward FUT8,whereas TGF-β1 promotes abnormal glycosylation of SEMA7A via induction of epithelial–mesenchymal transition.Aberrant N-glycosylation of SEMA7A leads to the differentiation of CD8^(+)T cells along a trajectory toward an exhausted state,thus shaping an immunosuppressive microenvironment and being resistant immunogenic cell death.Deglycosylation of SEMA7A significantly improves the clinical outcome of EGFR-targeted and anti-PD-L1-based immunotherapy.Finally,we also define RBM4,a splice regulator,as a downstream effector of glycosylated SEMA7A and a pivotal mediator of PD-L1 alternative splicing.These findings suggest that targeting FUT8-SEMA7A axis might be a promising strategy for improving antitumor responses in head and neck squamous cell carcinoma patients. 展开更多
关键词 ABERRANT SQUAMOUS SEMA
下载PDF
Evaluation of corneal parameter changes under different accommodative stimuli with Scheimpflug imaging-based tomography
3
作者 Farid J Bedrán-García David P Piñero 《国际眼科杂志》 CAS 2024年第9期1357-1366,共10页
AIM:To evaluate the reliability of measurements of corneal changes with accommodation in healthy eyes using a Scheimpflug imaging-based system and how these measurements distribute in the normal population.METHODS:Pro... AIM:To evaluate the reliability of measurements of corneal changes with accommodation in healthy eyes using a Scheimpflug imaging-based system and how these measurements distribute in the normal population.METHODS:Prospective,non-randomized,comparative study including 27 healthy subjects(54 eyes),including emmetropia(13 eyes),myopia(17 eyes),hyperopia(4 eyes)and astigmatism(20 eyes)groups.In all cases,a complete eye examination was performed,including the analysis of corneal changes with different accommodative stimuli(+2.00,0.00 and-3.00 D)using the Pentacam AXL system.The investigation was structured in 2 phases:repeatability analysis and characterization of accommodation-related corneal changes in healthy populations.RESULTS:In the repeatability analysis,the index of height asymmetry(IHA)showed the greatest variability with the three accommodative stimuli,being the results for the rest of parameters acceptable.The group of emmetropes showed significant differences with accommodative changes in the position of maximum keratometry(Kmax;P<0.05),whereas in the astigmatism group,significant changes were not only observed in the position of Kmax,but also in minimum corneal thickness(MCT),corneal spherical aberration,and total and low order aberration root mean square(all P<0.05).Likewise,a significant difference was found in the displacement of the X position of Kmax with+2.00 D and-3.00 D in the myopia group(P=0.033)as well as in changes with+2.00 D and-3.00 D in the magnitude of the position vector of Kmax in the emmetropia group(P<0.05).No significant changes were found between accommodative stimuli in the displacement of coordinates of MCT(P≥0.109).CONCLUSION:The position of Kmax and MCT in healthy corneas can change significantly when presenting different accommodative stimuli using the accommodation mode of the Pentacam system,with different trends in these accommodation-related corneal changes between refractive errors.Likewise,the consistency of the measurements obtained with Scheimpflug has been confirmed. 展开更多
关键词 corneal biomechanics KERATOMETRY corneal thickness PACHYMETRY corneal aberrations PENTACAM ACCOMMODATION
下载PDF
The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair
4
作者 Heeseog Kang Amy L.Strong +15 位作者 Yuxiao Sun Lei Guo Conan Juan Alec C.Bancroft Ji Hae Choi Chase A.Pagani Aysel A.Fernandes Michael Woodard Juhoon Lee Sowmya Ramesh Aaron W.James David Hudson Kevin N.Dalby Lin Xu Robert J.Tower Benjamin Levi 《Bone Research》 SCIE CAS CSCD 2024年第2期289-301,共13页
While hypoxic signaling has been shown to play a role in many cellular processes,its role in metabolism-linked extracellular matrix(ECM)organization and downstream processes of cell fate after musculoskeletal injury r... While hypoxic signaling has been shown to play a role in many cellular processes,its role in metabolism-linked extracellular matrix(ECM)organization and downstream processes of cell fate after musculoskeletal injury remains to be determined.Heterotopicossification(HO)is a debilitating condition where abnormal bone formation occurs within extra-skeletal tissues.Hypoxia andhypoxia-inducible factor 1α(HIF-1α)activation have been shown to promote HO.However,the underlying molecular mechanisms bywhich the HIF-1αpathway in mesenchymal progenitor cells(MPCs)contributes to pathologic bone formation remain to beelucidated.Here,we used a proven mouse injury-induced HO model to investigate the role of HIF-1αon aberrant cell fate.Usingsingle-cell RNA sequencing(scRNA-seq)and spatial transcriptomics analyses of the HO site,we found that collagen ECM organizationis the most highly up-regulated biological process in MPCs.Zeugopod mesenchymal cell-specific deletion of Hif1α(Hoxa11-CreER^(T2);Hif1a^(fl/fl))significantly mitigated HO in vivo.ScRNA-seq analysis of these Hoxa11-CreER^(T2);Hif1a^(fl/fl)mice identified the PLOD2/LOXpathway for collagen cross-linking as downstream of the HIF-1αregulation of HO.Importantly,our scRNA-seq data and mechanisticstudies further uncovered that glucose metabolism in MPCs is most highly impacted by HIF-1αdeletion.From a translational aspect,a pan-LOX inhibitor significantly decreased HO.A newly screened compound revealed that the inhibition of PLOD2 activity in MPCssignificantly decreased osteogenic differentiation and glycolytic metabolism.This suggests that the HIF-1α/PLOD2/LOX axis linked tometabolism regulates HO-forming MPC fate.These results suggest that the HIF-1α/PLOD2/LOX pathway represents a promisingstrategy to mitigate HO formation. 展开更多
关键词 METABOLISM SKELETAL ABERRANT
下载PDF
Characteristics of corneal aberration in patients with bilateral keratoconus and unilateral corneal Vogt’s striae
5
作者 Sheng-Sheng Wei Yong Li +4 位作者 Zhi-Qing Wu Jian-Guo Liu Jing Du Jing Li Yao-Hua Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第12期2316-2320,共5页
AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 ... AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 patients with KCN,whose corneas had definite signs of unilateral Vogt’s striae,were enrolled.Corneal HOA and morphological parameters were measured using Pentacam HR.RESULTS:The corneal morphological parameters between KCN eyes with and without Vogt’s striae were evidently different(P<0.001).The 3rd coma 90°,4th spherical aberration,5th coma 90°,root-mean-square(RMS)(total),and RMS(HOA)in the front,back surfaces and total cornea in KCN eyes with Vogt’s striae were significantly higher than those in KCN eyes without Vogt’s striae(P<0.001).In KCN eyes with Vogt’s striae,the 3rd coma 90°and 4th spherical aberration in the front surface and total cornea were negatively correlated with flat keratometry value(K1),steep keratometry value(K2),mean keratometry value(Km),maximum keratometry value(Kmax),anterior corneal elevation(ACE),and posterior corneal elevation(PCE;P<0.05).The 3rd coma 90°,4th spherical aberration in back surface and RMS(total),RMS(HOA)in the front,back surfaces,total cornea were positively correlated with K1,K2,Km,Kmax,ACE,and PCE(P<0.05).CONCLUSION:Corneal HOA especially vertical coma and spherical aberration may increase when Vogt’s striae appeared in KCN eyes.The scale of increase is significantly related with changes in corneal shapes. 展开更多
关键词 KERATOCONUS CORNEA corneal aberration corneal morphological Vogt’s striae
原文传递
Changes in visual performance after implantation of different intraocular lenses
6
作者 Bo-Wen Li Hao Huang +10 位作者 Man-Sha Huang Shuang-Lin Guo Lu Gao Yu-Ying Zeng Lu Cheng Si-Yang Yao Jian-Qiang Lin Lin Liu Ye Yang Xiao-Ming Lu Hao Cheng 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第7期1273-1282,共10页
AIM:To evaluate the trending visual performance of different intraocular lenses(IOLs)over time after implantation.METHODS:Ninety-one patients received cataract surgery with implantations of monofocal(Mon)IOLs,segmenta... AIM:To evaluate the trending visual performance of different intraocular lenses(IOLs)over time after implantation.METHODS:Ninety-one patients received cataract surgery with implantations of monofocal(Mon)IOLs,segmental refractive(SegRef)IOLs,diffractive(Dif)IOLs,and extendeddepth-of-focus(EDoF)IOLs were included.The aberrations and optical quality collected with iTrace and OQAS within postoperative 6mo were followed and compared.RESULTS:Most of the visual parameters improved over the postoperative 6mo.The postoperative visual acuity(POVA)of the Mon IOL,SegRef IOL,and EDoF IOL groups achieved relative stability in earlier states compared with the Dif IOL group.Nevertheless,the overall visual performance of the 3 IOLs continued to upturn in small extents within the postoperative 6mo.The optical quality initially improved in the EDoF IOL group,then in the Mon IOL,SegRef IOL,and Dif IOL groups.POVA and objective visual performance of the Mon IOL and EDoF IOL groups,as well as POVA and visual quality of the Dif IOL group,improved in the postoperative 1mo and stabilized.Within the postoperative 6mo,gradual improvements were observed in the visual acuity and objective visual performance of the SegRef IOL group,as well as in the postoperative optical quality of the Dif IOL group.CONCLUSION:The visual performance is different among eyes implanted with different IOLs.The findings of the current study provide a potential reference for ophthalmologists to choose suitable IOLs for cataract patients in a personalized solution. 展开更多
关键词 intraocular lenses visual performance changing characteristics high-order wavefront aberration
原文传递
Stimulated Raman scattering microscopy with phase-controlled light focusing and aberration correction for rapid and label-free, volumetric deep tissue imaging
7
作者 Weiqi Wang Zhiwei Huang 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第9期40-52,共13页
We report a novel stimulated Raman scattering(SRS)microscopy technique featuring phase-controlled light focusing and aberration corrections for rapid,deep tissue 3D chemical imaging with subcellular resolution.To acco... We report a novel stimulated Raman scattering(SRS)microscopy technique featuring phase-controlled light focusing and aberration corrections for rapid,deep tissue 3D chemical imaging with subcellular resolution.To accomplish phasecontrolled SRS(PC-SRS),we utilize a single spatial light modulator to electronically tune the axial positioning of both the shortened-length Bessel pump and the focused Gaussian Stokes beams,enabling z-scanning-free optical sectioning in the sample.By incorporating Zernike polynomials into the phase patterns,we simultaneously correct the system aberrations at two separate wavelengths(~240 nm difference),achieving a~3-fold enhancement in signal-to-noise ratio over the uncorrected imaging system.PC-SRS provides>2-fold improvement in imaging depth in various samples(e.g.,polystyrene bead phantoms,porcine brain tissue)as well as achieves SRS 3D imaging speed of~13 Hz per volume for real-time monitoring of Brownian motion of polymer beads in water,superior to conventional point-scanning SRS 3D imaging.We further utilize PC-SRS to observe the metabolic activities of the entire tumor liver in living zebrafish in cellsilent region,unraveling the upregulated metabolism in liver tumor compared to normal liver.This work shows that PCSRS provides unprecedented insights into morpho-chemistry,metabolic and dynamic functioning of live cells and tissue in real-time at the subcellular level. 展开更多
关键词 SRS 3D imaging phase-controlled light focusing image aberration corrections deep tissue imaging
下载PDF
Multidimensional images and aberrations in STEM
8
作者 Eric R.Hoglund Andrew R.Lupini 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期68-74,共7页
Recent advances in scanning transmission electron microscopy(STEM)have led to increased development of multidimensional STEM imaging modalities and novel image reconstruction methods.This interest arises because the m... Recent advances in scanning transmission electron microscopy(STEM)have led to increased development of multidimensional STEM imaging modalities and novel image reconstruction methods.This interest arises because the main electron lens in a modern transmission electron microscope usually has a diffraction-space information limit that is significantly better than the real-space resolution of the same lens.This state-of-affairs is sometimes shared by other scattering methods in modern physics and contributes to a broader excitement surrounding multidimensional techniques that scan a probe while recording diffraction-space images,such as ptychography and scanning nano-beam diffraction.However,the contrasting resolution in the two spaces raises the question as to what is limiting their effective performance.Here,we examine this paradox by considering the effects of aberrations in both image and diffraction planes,and likewise separate the contributions of pre-and post-sample aberrations.This consideration provides insight into aberration-measurement techniques and might also indicate improvements for super-resolution techniques. 展开更多
关键词 scanning transmission electron microscopy(STEM) ABERRATIONS
原文传递
Integrated Test System for Large-aperture Telescopes Based on Astrophotonics Interconnections
9
作者 Qichang An Kun Wang +2 位作者 Xinyue Liu Hongwen Li Jiakang Zhu 《Instrumentation》 2024年第1期1-9,共9页
This study aims to improve the integrated testing of large-aperture telescopes to clarify the fundamental principles of an integrated testing system based on astrophotonics.Our demonstration and analyses focused on el... This study aims to improve the integrated testing of large-aperture telescopes to clarify the fundamental principles of an integrated testing system based on astrophotonics.Our demonstration and analyses focused on element-position sensing and modulation based on spatial near-geometric beams,high-throughput step-difference measurements based on channel spectroscopy,distributed broadband-transmittance testing,and standard spectral tests based on near-field energy regulation.Comprehensive analyses and experiments were conducted to confirm the feasibility of the proposed system in the integrated testing process of large-aperture telescopes.The results demonstrated that the angular resolution of the light rays exceeded 5arcsec,which satisfies the requirements for component-position detection in future large-aperture telescopes.The measurement resolution of the wavefront tilt was better than 0.45μrad.Based on the channel spectral method—which combined a high signal-to-noise ratio and high sensitivity,along with continuous-spectral digital segmentation and narrowband-spectral physical segmentation—a resolution of 0.050μm and a range of 50μm were obtained.After calibration,the measurement resolution of the pupil deviation improved to exceed 4%accuracy,and the transmission measurements achieved a consistency of over 2%accuracy.Regarding fringe-broadband interferometry measurements,the system maintained high stability,ensuring its operation within the coherence length,and robustly detected the energy without unwrapping the phase.The use of a projector for calibrating broadband-spectrum measurements led to a reduction in contrast from 0.8142 to 0.6038,which further validates the system's applicability in the integrated testing process of large-aperture telescopes.This study greatly enhanced the observational capabilities of large-aperture telescopes while reducing the integrated system's volume,weight,and power consumption. 展开更多
关键词 curvature sensing wavefront aberration astrophotonics large-aperture telescope
原文传递
Orthokeratology with increased compression factor in adolescent myopia control:a 2-year prospective randomized clinical trial 被引量:4
10
作者 Wen-Ting Tang Li Zhang +2 位作者 Hui-Dan Zhang Shi-Bei Li Hao Liang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第5期770-777,共8页
AIM:To explore the long-term efficacy,safety,and optical mechanism of orthokeratology with increased compression factor in adolescent myopia control.METHODS:A prospective,double-masked,and randomized clinical trial wa... AIM:To explore the long-term efficacy,safety,and optical mechanism of orthokeratology with increased compression factor in adolescent myopia control.METHODS:A prospective,double-masked,and randomized clinical trial was performed from May 2016 to June 2020.Subjects aged between 8 and 16y,with myopia(-5.00 to-1.00 D),low astigmatism(≥-1.50 D)and anisometropia(≤1.00 D),were stratified into low(-2.75 to-1.00 D)and moderate(-5.00 to-3.00 D)myopia groups.Then they were randomly assigned to wear either increased compression factor(ICF;1.75 D)orthokeratology or conventional compression factor(CCF;0.75 D)orthokeratology.The data were recorded including axial length(AL),spherical equivalent(SE),best corrected visual acuity(BCVA),near visual acuity(NVA),corneal staining(using Efron grading scales),corneal hysteresis(CH),corneal resistance factor(CRF),higher-order aberrations(HOAs,expressed as root mean square,RMS_(h)),and subfoveal choroidal thickness(SFCh T)in the 2-year followup period.Pearson's correlation coefficient was conducted to analyze the association between the changes in AL and RMS_(h),SFCh T.RESULTS:At the 2-year visit,there were no statistical differences in all the parameters between the ICF group and the CCF group in low myopia subjects(P>0.05).For the moderate myopia subjects,the ICF group had shorter AL elongation(0.23±0.08 vs 0.30±0.11 mm,P=0.015),higher RMS_(h)(1.94±0.50 vs 1.65±0.51μm,P=0.041),and higher SFCh T(279.04±35.72 vs 254.08±29.60μm,P=0.008)than those in CCF group.The change in AL was negatively correlated with RMS_(h)(r=-0.687,P<0.001)and SFCh T(r=-0.464,P=0.013).CONCLUSION:ICF orthokeratology can control the progression of moderate myopia more effectively,which might be related to greater RMS_(h) and SFCh T. 展开更多
关键词 ORTHOKERATOLOGY compression factor MYOPIA axial length higher-order aberrations choroidal thickness
原文传递
Symmetrical femtosecond laser arc incision in correcting corneal astigmatism in cataract patients 被引量:2
11
作者 Zun-Xia Hu Jing Sima +8 位作者 Jia-Guo Cao Yan Ke Ying-Ying Zhang Qiong-Tian Guo Yu-Ping He Hong-Xia Liao Xiao Tan Bo Qin Li Li 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第12期1996-2003,共8页
AIM:To evaluate the effect of symmetrical arc incision correcting corneal astigmatism in femtosecond laserassisted phacoemulsification(FLACS).METHODS:This study enrolled patients with cataract combined with regular co... AIM:To evaluate the effect of symmetrical arc incision correcting corneal astigmatism in femtosecond laserassisted phacoemulsification(FLACS).METHODS:This study enrolled patients with cataract combined with regular corneal astigmatism of>0.75 D,who underwent FLACS.Symmetrical arc incision was set at 8 mm diameter and 85%depth.The follow-up time was 3-24mo(4.92±3.49mo).Pentacam recorded the corneal astigmatism and higher-order aberration at pre-operation and post-operation.The changes in corneal astigmatism were analyzed by Alpins method.The correlation of astigmatism type,age,corneal horizontal diameter,corneal thickness,arc incision length,and correction index(CI)was analyzed,and the residual corneal astigmatism was compared with the residual whole eye astigmatism.RESULTS:Totally 79 patients(102 eyes)were enrolled,10 patients had corneal epithelial injury,1 patient occurred corneal epithelial hyperplasia.The corneal astigmatism was 1.23±0.38 D pre-operation,and decreased to 0.76±0.39 D post-operation(t=10.146,P=0.000).Corneal high-order aberration was 0.17±0.08μm pre-operation and 0.24±0.11μm post-operation(t=-5.186,P=0.000).The residual corneal astigmatism and residual whole eye astigmatism were no significant difference(t=-0.347,P=0.729).Using Alpin’s method,the following were determined:target-induced astigmatism(TIA)=1.23±0.38 D,surgeryinduced astigmatism(SIA)=0.77±0.45 D,difference vector(DV)=0.77±0.39 D,and CI=0.54±0.28.Age,astigmatism size,corneal horizontal diameter,corneal thickness,and arc incision length were not correlated with CI.The CI for against the rule astigmatism(ATR)was better than that for with the rule astigmatism(WTR;P=0.001).CONCLUSION:Femtosecond laser-assisted astigmatic keratotomy has better CI of ATR,but increase higher-order corneal aberration.CI is not ideal,it’s not a perfect choice if we pursue ideal correction effect. 展开更多
关键词 femtosecond laser arc incision keratotomy ASTIGMATISM CATARACT higher-order aberrations
原文传递
Comparative study of functional optical zone:small incision lenticule extraction versus femtosecond laser assisted excimer laser keratomileusis 被引量:2
12
作者 Yao-Wen Song Meng-Fan Cui +3 位作者 Yi Feng Min Qu Yan Gao Rui He 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第2期238-244,共7页
AIM:To investigate the size of functional optical zone(FOZ)after small incision lenticule extraction(SMILE)versus femtosecond laser assisted excimer laser keratomileusis(FS-LASIK)for myopia correction and potential as... AIM:To investigate the size of functional optical zone(FOZ)after small incision lenticule extraction(SMILE)versus femtosecond laser assisted excimer laser keratomileusis(FS-LASIK)for myopia correction and potential associated factors for FOZ.METHODS:A total of 133 patients who received corneal refractive surgery in our hospital between November 2018 and July 2021 were retrospectively enrolled.There were 63 patients(123 eyes)in SMILE group and 70patients(139 eyes)in FS-LASIK group.The size of FOZ was measured using Pentacam 3-dementional anterior segment analyzer before and 3mo after surgery,so as to analyze postoperative achieved functional optical zone(AFOZ)and its contributing parameters.RESULTS:When planned functional optical zone(PFOZ)was 6.5 mm for both groups,AFOZ was 1.45±0.27 and 1.67±0.25 mm smaller than preoperative FOZ in SMILE group and FS-LASIK group 3mo after surgery.AFOZ in SMILE group was significantly larger than that in FS-LASIK group(P<0.001).Variation of FOZ was negatively correlated with preoperative spherical equivalent(SE)and positively correlated with variation of mean keratometry value(△Km),variation of spherical aberration(△SA),and variation of Q-value(△Q,all P<0.001)in both groups.Multiple variable linear regression equations were△FOZ=1.354-0.1×pre-SE+0.336×△Q+1.462×△SA in SMILE group and△FOZ=1.512+0.137×△Q+0.468×△SA in FS-LASIK group.CONCLUSION:AFOZ is significantly smaller than preoperative FOZ in both SMILE and FS-LASIK groups.With the same PFOZ,larger AFOZ is achieved in SMILE group than in FS-LASIK group. 展开更多
关键词 functional optical zone small incision lenticule extraction femtosecondlaser assisted excimer laser keratomileusis spherical equivalent spherical aberration
原文传递
Design of 50 MeV proton microbeam based on cyclotron accelerator 被引量:1
13
作者 Hong-Jin Mou Guang-Bo Mao +8 位作者 Jin-Quan Zhang Can Zhao Jin-Long Guo Wen-Jing Liu Ru-Qun Wu Cheng Shen Lei Zhang Jun-Shuai Li Guang-Hua Du 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第6期55-68,共14页
High-energy proton microbeam facilities are powerful tools in space science,biology and cancer therapy studies.The primary limitations of the 50 MeV proton microbeam system are the poor beam quality provided by the cy... High-energy proton microbeam facilities are powerful tools in space science,biology and cancer therapy studies.The primary limitations of the 50 MeV proton microbeam system are the poor beam quality provided by the cyclotron and the problem of intense scattering in the slit position.Here,we present an optical design for a cyclotron-based 50 MeV high-energy proton microbeam system with a micron-sized resolution.The microbeam system,which has an Oxford triplet lens configuration,has relatively small spherical aberrations and is insensitive to changes in the beam divergence angle and momentum spread.In addition,the energy filtration included in the system can reduce the beam momentum spread from 1 to 0.02%.The effects of lens parasitic aberrations and the lens fringe field on the beam spot resolution are also discussed.In addition,owing to the severe scattering of 50 MeV protons in slit materials,a slit system model based on the Geant4 toolkit enables the quantitative analysis of scattered protons and secondary particles.For the slit system settings under a 10-micron final beam spot,very few scattered protons can enter the quadrupole lens system and affect the focusing performance of the microbeam system,but the secondary radiation of neutrons and gamma rays generated at the collimation system should be considered for the 50 MeV proton microbeam.These data demonstrate that a 50 MeV proton microbeam system with a micron-sized beam spot based on a cyclotron is feasible. 展开更多
关键词 50 MeV proton MICROBEAM Beam optics ABERRATIONS Scattering
下载PDF
Efficacy of custom-made soft keratoconus lenses on corneal aberrations and photic phenomena in patients with keratoconus:a corneal topography imaging based study
14
作者 Aysegul Penbe Hatice Selen Kanar +1 位作者 Aysu Karatay Arsan Sevda Aydın Kurna 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第1期67-74,共8页
AIM:To evaluate the efficacy of custom-made soft keratoconus(KC)lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.METHODS:Sixty eyes of 42 patients with KC were exam... AIM:To evaluate the efficacy of custom-made soft keratoconus(KC)lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.METHODS:Sixty eyes of 42 patients with KC were examined at baseline and after fitting HydroCone(Toris K)soft silicone hydrogel lenses.Best spectacle-corrected visual acuity(BSCVA)and contact lens-corrected visual acuity(CLCVA)were recorded.Lower-and higher-order corneal aberrations(LOAs and HOAs)were measured with and without Toris K lenses and compared in central 4.5 mm and 7 mm zones.Mesopic pupil diameter and subjective photic phenomena were also assessed.RESULTS:Mean CLCVA was significantly improved compared to BSCVA(P<0.0001).Corneal curvature and refractive measurements were found to be significantly reduced by the use of Toris K lenses,except for posterior corneal curvature values.In the 4.5 mm central optical zone,all wavefront aberrations decreased significantly after lens fitting(P<0.0001).In contrast,in the 7 mm(peripheral)optical zone,values for HOAs,spherical and residual aberrations,and optical path differences were increased,while LOAs,trefoil,and quadrifoil coefficients were decreased.The rate of photic phenomena was significantly higher in participants with a pupil size>6.00 mm(85.7%).CONCLUSION:Toris K lenses provide good visual results and a significant reduction in central corneal aberrations in patients with KC but could cause an increase in peripheral aberrations.This practical and nonsurgical approach appears to be an effective method for the visual management of KC. 展开更多
关键词 corneal aberrations custom-made soft keratoconus lenses higher-order aberrations KERATOCONUS lower-order aberrations PUPILLOGRAPHY
原文传递
Rendering algorithms for aberrated human vision simulation
15
作者 István Csoba Roland Kunkli 《Visual Computing for Industry,Biomedicine,and Art》 EI 2023年第1期51-75,共25页
Vision-simulated imagery―the process of generating images that mimic the human visual system―is a valuable tool with a wide spectrum of possible applications, including visual acuity measurements, personalized plann... Vision-simulated imagery―the process of generating images that mimic the human visual system―is a valuable tool with a wide spectrum of possible applications, including visual acuity measurements, personalized planning of corrective lenses and surgeries, vision-correcting displays, vision-related hardware development, and extended reality discomfort reduction. A critical property of human vision is that it is imperfect because of the highly influential wavefront aberrations that vary from person to person. This study provides an overview of the existing computational image generation techniques that properly simulate human vision in the presence of wavefront aberrations. These algorithms typically apply ray tracing with a detailed description of the simulated eye or utilize the point-spread func-tion of the eye to perform convolution on the input image. Based on the description of the vision simulation tech-niques, several of their characteristic features have been evaluated and some potential application areas and research directions have been outlined. 展开更多
关键词 Human vision Human visual system Vision simulation Wavefront aberrations Visual aberrations Vision-realistic rendering
下载PDF
One-year clinical efficacy evaluation of selective corneal wavefront aberration-guided FS-LASIK correction in patients with high myopia
16
作者 Zhong-Ji Li Su-Han Liu +2 位作者 Chen Yang Jiao Guo Yu-Hui Duan 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第8期1280-1286,共7页
AIM:To evaluate the effectiveness,safety,predictability,precision and changes of higher-order aberrations(HOAs)on corneal front surface of selective corneal wavefront aberration-guided femtosecond laser-assisted in si... AIM:To evaluate the effectiveness,safety,predictability,precision and changes of higher-order aberrations(HOAs)on corneal front surface of selective corneal wavefront aberration-guided femtosecond laser-assisted in situ keratomileusis(CW-FS-LASIK)in patients with high myopia 1-year postoperatively.METHODS:Totally 74 eyes of 37 patients with high myopia or myopic astigmatism in both the eyes who underwent the CW-FS-LASIK procedure in Xi’an Gaoxin Hospital from January 2021 to June 2021 were included.The changes of uncorrected distance visual acuity(UDVA),best corrected visual acuity(BCVA),spherical equivalent refraction(SER),astigmatism,HOAs and Strehl ratio(SR)on the anterior surface of the cornea after 1y of the surgery were analyzed.RESULTS:At postoperative 1y,the UDVA(logMAR)of 74 eyes(100%)reached 0 or better,including 0 in 8 eyes(10.81%),-0.1 in 45 eyes(60.81%),and-0.2 in 21 eyes(28.38%).The effectiveness index was 1.29±0.134.There was no decrease in postoperative BCVA compared with preoperative BCVA in all patients.Postoperative BCVA was the same in 44 eyes(59.46%)as preoperative BCVA,increased by 1 line in 23 eyes(31.08%)and increased by 2 lines in 7 eyes(9.46%)compared with preoperative BCVA.The safety index was 1.11±0.159.The estimated corrected SER before surgery was(-7.76±1.21)D,and the actual corrected SER was(-7.83±1.25)D(Y=0.9811X+0.2156,R2=0.9084).There was a high correlation between the estimated corrected SER and the actual corrected SER.The postoperative SER in 74 eyes(100%)was within±0.75 D.The postoperative astigmatism of all was within-0.75 D to 0.Root mean square(RMS)HOAs of spherical aberration and SR within 5 mm of the corneal front surface were all increased compared with those before operation(P<0.01).The total coma,horizontal coma and vertical coma were all decreased compared with those before operation(P<0.01).There was no statistically significant difference in horizontal trefoil and vertical trefoil compared with preoperative ones(P>0.05).CONCLUSION:Selective CW-FS-LASIK for correction of high myopia is effective,safe,predictive,and accurate.For patients with preoperative RMS HOAs over 0.25 defocus equivalent,postoperative coma aberration can be significantly reduced,and SR value can be increased,thus corneal imaging quality can be improved. 展开更多
关键词 corneal aberration FS-LASIK effectiveness safety PREDICTABILITY precision
原文传递
Study of strip-shaped chromatic aberration defects on the surface of an electro-galvanized fingerprint-resistant sheet
17
作者 HE Yutian HUANG Shengbiao ZHANG Baoping 《Baosteel Technical Research》 CAS 2023年第2期7-14,共8页
Strip-shaped chromatic aberration defects on the surface of an electro-galvanized fingerprint-resistant sheet were systematically studied using Thermo-Calc thermodynamic calculations,scanning electron microscope and X... Strip-shaped chromatic aberration defects on the surface of an electro-galvanized fingerprint-resistant sheet were systematically studied using Thermo-Calc thermodynamic calculations,scanning electron microscope and X-ray diffractometer analyses,and rapid heat treatment simulation technology.The formation mechanism of these defects was also analyzed.The results show a strong correlation between the defects and the uneven distribution of the Fe(001)component on the surface of the steel substrate.The relatively high proportion of Fe(001)components on the surface of the steel substrate affects the distribution density of the Zn crystal cells in different orientations during the electrodeposition process,which causes the reflection intensity of the light of the galvanized layer to differ from various visual perspectives,and macroscopic strip-shaped chromatic aberration defects are finally formed.The high proportion of the Fe(001)component on the surface of the steel substrate is mainly related to the following two factors.First,when the strip steel is hot-rolled,the finishing hot-rolling temperature is close to theγ→αphase transition temperature.When the local temperature on the upper surface of the strip steel is low,γ+αtwo-phase rolling easily occurs,and this results in an uneven stress distribution between theγandαphases after the hot-rolling process.This uneven distribution of hot-rolling stress results in the formation of a coarse grain structure in the local area on the surface of the hot-rolled sheet,which strongly affects the subsequent cold rolling and annealing process,and the annealed steel sheet substrate ultimately contains a greater proportion of the Fe(001)component.And second,a fast cooling rate(>10 K/s)during the slow cooling stage in the continuous annealing process inhibits the transformation of the Fe(001)to the Fe(111)component on the surface of the cold-rolled steel sheet,and it is then not possible to effectively eliminate the influence of the unevenly distributed Fe(001)component on the surface of the annealed steel sheet(originating from the uneven hot-rolled microstructure).This uneven distribution of the Fe(001)component on the surface of the annealed steel sheet following the continuous annealing heat treatment has a strong effect on the electrodeposition behavior of the Zn crystal cell in the subsequent electroplating process and the formation of macroscopic strip-shaped chromatic aberration defects on the surface of electro-galvanized fingerprint-resistant sheet. 展开更多
关键词 electro-galvanized fingerprint-resistant sheet strip-shaped chromatic aberration defects texture
下载PDF
Carotid-subclavian bypass and endovascular aortic repair of Kommerell’s diverticulum with aberrant left subclavian artery:A case report
18
作者 Wajeehullahi Akilu Yi Feng +4 位作者 Xiao-Xue Zhang Shi-Liang Li Xian-Tao Ma Min Hu Cai Cheng 《World Journal of Clinical Cases》 SCIE 2023年第33期8038-8043,共6页
BACKGROUND Kommerell’s diverticulum(KD)with aberrant left subclavian artery is a rare congenital deformity and also has very little research literature about it(35%of case study).There are three types of aortic arch ... BACKGROUND Kommerell’s diverticulum(KD)with aberrant left subclavian artery is a rare congenital deformity and also has very little research literature about it(35%of case study).There are three types of aortic arch diverticulum.Even literature concerning the treatment options are limited.CASE SUMMARY We present a case report of a 50-year-old male with KD in the right aortic arch with aberrant left subclavian artery.We conducted a total endovascular repair procedure,which is innovative and will spread more light in the medical world.Our patient has no past medical history and is a non-smoker and non-alcoholic.Patient presented with shortness of breath,chest pain and dizziness for six months.Blood tests were done and computerized tomography(CT)angiogram of the chest confirmed the diagnosis,illustrating showed a 3.9 cm KD.On Day 1,the CT angiogram showed mild dilatation of the thoracic aorta,adjacent esophagus,trachea was compressed and displaced.Surgery was planned as the treatment modality.Carotid-Subclavian artery bypass and endovascular aortic repair was conducted.We used prolene 5-0 C1 sutures to precisely anastomose a 6-mm Dacron graft to the left subclavian artery.Haemostasis was secured and wounds were closed.Protamine was administered and patient was shifted to intensive care unit.Post-operative,patient responded favorably and was discharged.Regular follow-up is done.CONCLUSION The procedure we performed is novel.This will help the cardio-thoracic surgeons a better insight about the full procedures we conducted,thereby bringing more light and better treatment options in managing KD with aberrant subclavian artery. 展开更多
关键词 Kommerell’s diverticulum Left common carotid artery Aberrant left subclavian artery Carotid-subclavian bypass Medtronic stent catheter endovascular repair Case report
下载PDF
深度学习与边缘增强相结合的断裂综合检测技术——顺北地区超深走滑断裂检测应用实例 被引量:6
19
作者 陈俊安 陈海东 +1 位作者 龚伟 廖茂辉 《石油地球物理勘探》 EI CSCD 北大核心 2022年第6期1304-1316,I0002,共14页
塔里木盆地顺北地区超深断控缝洞型储集体发育,近年来不断有高产井涌现;同时,大量研究证实高角度走滑断裂对油气藏的运移和聚集起决定性作用。受“断控储集体”埋藏深,且走滑断裂断距小、难闭合等因素的影响,顺北地区地震资料信噪比低... 塔里木盆地顺北地区超深断控缝洞型储集体发育,近年来不断有高产井涌现;同时,大量研究证实高角度走滑断裂对油气藏的运移和聚集起决定性作用。受“断控储集体”埋藏深,且走滑断裂断距小、难闭合等因素的影响,顺北地区地震资料信噪比低、断面特征不清晰,导致走滑断裂检测及空间解释难度较大。针对上述超深走滑断裂检测研究面临的难点,文中提出深度学习与边缘增强相结合的多尺度断裂综合检测技术:首先将走滑断裂按规模划分为主干断裂、伴生次级断裂、小尺度裂缝;通过正演主干断裂、次级断裂、裂缝等不同断裂模式的地震响应特征并进行方法实验,认为可应用U-Net卷积神经网络深度学习技术识别主干断裂、振幅梯度矢量凌乱性检测技术识别伴生次级断裂、Aberrance增强属性识别小尺度裂缝。将该套技术应用于顺北地区走滑断裂实际检测中,取得了显著效果。 展开更多
关键词 超深走滑断裂 地震模式识别 深度学习 凌乱性检测 aberrance增强
下载PDF
Studies on Ultra-dry Storage and Genetic Stability of Vegetable Seeds 被引量:2
20
作者 孟淑春 李秀清 +2 位作者 马连平 卢艳 刘玲 《Agricultural Science & Technology》 CAS 2011年第12期1853-1856,共4页
[Objective] To study the long-term ultra-dry storage method and genetic stability of vegetable seeds.[Method] Seeds of Lycopersicum esculentum,Raphanus satuvus and Apium graveolen.were chosen as material.The changes o... [Objective] To study the long-term ultra-dry storage method and genetic stability of vegetable seeds.[Method] Seeds of Lycopersicum esculentum,Raphanus satuvus and Apium graveolen.were chosen as material.The changes of seed vigor,viability and genetic stability after ultra-storage were discussed by studying the seed potentiality,shoot length,germination percentage and the chromosome aberration rate of root tip cells.[Results] Maintaining the low moisture content,different vegetable species had different storage effects of the long-term storage seeds under normal temperature.The Lycopersicum esculentum and Raphanus satuvus seeds were more suitable to ultra-dry storage at normal temperature,and could keep good genetic stability,while the seeds of Apium graveolen had bad performance.[Conclusion] This study established the foundation of studying ultra-dry storage of vegetable seeds. 展开更多
关键词 SEEDS Ultra-dry storage Chromosome aberration Genetic stability
下载PDF
上一页 1 2 23 下一页 到第
使用帮助 返回顶部