<span style="font-family:Verdana;">The subjects of this study were 80 patients who underwent mixed hemorrhoids surgery in our hospital from January to October 2020 (mixed hemorrhoids external and inter...<span style="font-family:Verdana;">The subjects of this study were 80 patients who underwent mixed hemorrhoids surgery in our hospital from January to October 2020 (mixed hemorrhoids external and internal ligation, internal hemorrhoids ligation or Xiaozhiling injection) and developed anal edge edema after surgery. According to the order of hospitalization, the patients were randomly divided into treatment group and control group, with 40 cases each.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">In the control group, blank hot pack was applied on the basis of anorectal No. 1 lotion for prevention and treatment of anal edge edema after operation;in the treatment group, hot pack of Traditional Chinese medicine was applied on the basis of anorectal No. 1 lotion for prevention and treatment of anal edge edema. The course of treatment was 7 days.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">The edema subsidence and postoperative pain scores were observed in both groups.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">Results: The scores of anal edema and pain in the treatment group were significantly lower than those in the control group (P < 0.05), and the significant efficiency and total effective rate in the treatment group were significantly better than those in the control group, with statistical difference (P < 0.05).</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">Conclusion: Chinese medicine hot election package is effective in treating postoperative anal edema of mixed hemorrhoids, and the method is simple and suitable for clinical promotion.</span>展开更多
目的研究自拟活血化瘀方对肛肠术后组织内成纤维细胞的表达量的影响,进而减少肛肠术后并发症,促进伤口愈合。方法收集2019年12月-2020年10月就诊于河北省中医院肛肠科120例符合纳入标准的患者。随机选取60例患者作为对照组采用便后坐浴...目的研究自拟活血化瘀方对肛肠术后组织内成纤维细胞的表达量的影响,进而减少肛肠术后并发症,促进伤口愈合。方法收集2019年12月-2020年10月就诊于河北省中医院肛肠科120例符合纳入标准的患者。随机选取60例患者作为对照组采用便后坐浴换药等常规临床治疗,余60例在常规治疗基础上加用自拟活血化瘀方内服作为治疗组。统计各组治疗后症候积分,观察临床疗效并随访愈合时间。取术后3、7、14天伤口增生的多余组织应用苏木精-伊红染色法(hematoxylin-eosin staining,HE)染色观察术后组织内肉芽组织形成情况,应用免疫荧光染色技术,观察创口肉芽组织中成纤维细胞特异性蛋白-1(Fibroblast specific protein-1,FSP-1)的表达量。结果治疗组的各症候积分显著优于对照组;免疫荧光染色FSP-1发现,治疗组第7、14天FSP-1表达量显著多于对照组(P<0.05),两组差异具有统计学意义。治疗组伤口愈合时间明显短于对照组(P<0.05)。结论通过上述实验结果,推论自拟活血化瘀方可通过促进肛肠术后组织内成纤维细胞的增殖,在防治肛肠术后肛门疼痛、创缘水肿方面具有明显效果,可提高肛肠术后创伤愈合速度。展开更多
文摘<span style="font-family:Verdana;">The subjects of this study were 80 patients who underwent mixed hemorrhoids surgery in our hospital from January to October 2020 (mixed hemorrhoids external and internal ligation, internal hemorrhoids ligation or Xiaozhiling injection) and developed anal edge edema after surgery. According to the order of hospitalization, the patients were randomly divided into treatment group and control group, with 40 cases each.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">In the control group, blank hot pack was applied on the basis of anorectal No. 1 lotion for prevention and treatment of anal edge edema after operation;in the treatment group, hot pack of Traditional Chinese medicine was applied on the basis of anorectal No. 1 lotion for prevention and treatment of anal edge edema. The course of treatment was 7 days.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">The edema subsidence and postoperative pain scores were observed in both groups.</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">Results: The scores of anal edema and pain in the treatment group were significantly lower than those in the control group (P < 0.05), and the significant efficiency and total effective rate in the treatment group were significantly better than those in the control group, with statistical difference (P < 0.05).</span><span style="font-size:10.0pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:Verdana;" "="">Conclusion: Chinese medicine hot election package is effective in treating postoperative anal edema of mixed hemorrhoids, and the method is simple and suitable for clinical promotion.</span>
文摘目的研究自拟活血化瘀方对肛肠术后组织内成纤维细胞的表达量的影响,进而减少肛肠术后并发症,促进伤口愈合。方法收集2019年12月-2020年10月就诊于河北省中医院肛肠科120例符合纳入标准的患者。随机选取60例患者作为对照组采用便后坐浴换药等常规临床治疗,余60例在常规治疗基础上加用自拟活血化瘀方内服作为治疗组。统计各组治疗后症候积分,观察临床疗效并随访愈合时间。取术后3、7、14天伤口增生的多余组织应用苏木精-伊红染色法(hematoxylin-eosin staining,HE)染色观察术后组织内肉芽组织形成情况,应用免疫荧光染色技术,观察创口肉芽组织中成纤维细胞特异性蛋白-1(Fibroblast specific protein-1,FSP-1)的表达量。结果治疗组的各症候积分显著优于对照组;免疫荧光染色FSP-1发现,治疗组第7、14天FSP-1表达量显著多于对照组(P<0.05),两组差异具有统计学意义。治疗组伤口愈合时间明显短于对照组(P<0.05)。结论通过上述实验结果,推论自拟活血化瘀方可通过促进肛肠术后组织内成纤维细胞的增殖,在防治肛肠术后肛门疼痛、创缘水肿方面具有明显效果,可提高肛肠术后创伤愈合速度。
