The renewal of ancient cities is an important part of the urban renewal work in China.However,there are few studies on the general historical ancient cities at the county level in China,and there is no guidance on the...The renewal of ancient cities is an important part of the urban renewal work in China.However,there are few studies on the general historical ancient cities at the county level in China,and there is no guidance on the renewal path.Through the practice of the renewal design project of Suining County,Xuzhou City,it makes an exploratory study on the renewal concept and mode.It first interprets the connotation and implementation path of the renewal concept of“endowing the old with the new”.Based on the texture analysis of the ancient city of Suining,it finally determines the design theme that tracing the historical context of the ancient city.Using the renewal techniques such as“extraction-transformationactivation”,through the renewal strategies such as“building new space,shaping new landscape,inheriting new culture and pregnant with new environment”,it realizes the regeneration of urban historical context and meets the needs of residents'modern life,so as to provide reference and guidance for the renovation of general historical ancient cities at the county level in China.展开更多
In the context of controlling population development in a planned way,China entered an aging society in the early 21 st century.In this context,how to meet the needs of the elderly care and form an effective elderly c...In the context of controlling population development in a planned way,China entered an aging society in the early 21 st century.In this context,how to meet the needs of the elderly care and form an effective elderly care model has become a key problem to be solved urgently by local government departments.With the continuous advancement of the elderly care policy,the community-based elderly care has gradually become the mainstream and is in the stage of vigorous promotion.Taking the Gannan old revolutionary base area in Jiangxi Province as an example,this study puts forward"1+4+X"community-based elderly care model based on the policy system of community-based elderly care,the physical and mental health of the elderly,the material space and the construction of evaluation system,and explores how to promote the application of this community model efficiently in the form of industrialization,so as to drive the economic growth of the Gannan old revolutionary base area,promote the employment development and improve the community-based elderly care service.展开更多
Neurotrophins:Neurotrophins are peptides or proteins that are known to regulate neuronal viability,development,and function Beyond synaptic plasticity,neurotrophins protect neurons from apoptosis and also promote neu...Neurotrophins:Neurotrophins are peptides or proteins that are known to regulate neuronal viability,development,and function Beyond synaptic plasticity,neurotrophins protect neurons from apoptosis and also promote neurogenesis to recover neuronal defici even in adulthood.展开更多
Shanghai is changing in a big way. Xintiandi-New Heaven and Earth-a development of restoredlow-rise houses called Shikumen, or "stone gate"buildings, stands as a perfect symbol of the newShanghai.
“New Accounts of Old Episodes”is a classic handed down in China,which reflects the personality image and charm of the scholars in the Wei and Jin dynasties with the original ecological narrative technique.The schola...“New Accounts of Old Episodes”is a classic handed down in China,which reflects the personality image and charm of the scholars in the Wei and Jin dynasties with the original ecological narrative technique.The scholars of the Wei and Jin Dynasties were detached,facing the world with an aesthetic attitude beyond secular utilitarianism,etiquette,and real life,establish a graceful social stage of vulgarity,create a unique personality beauty,providing valuable ideological wealth for the cultivation of poetic spirit,poetic dwelling,aesthetic style,transcend personality,and wisdom.展开更多
With the development of socialism market economy, the former Bar Code ForCommodity Management Measures (being called Old Measures for short hereafter) issued by the NationalBureau of Quality and Technical Supervision ...With the development of socialism market economy, the former Bar Code ForCommodity Management Measures (being called Old Measures for short hereafter) issued by the NationalBureau of Quality and Technical Supervision can not adapt to the requirement of managing for barcode for commodity. Therefore, for the purpose of standardize bar code for commodity managementstandard, ensuring its quality, speeding up the application of it in electronic business andcirculating field and accelerating the course of being a well informed country, a new Bar Code ForCommodity Management Measures (New Measures for short) has been issued by the General Administratorof Quality Supervision, Inspection and Quarantine of P.R. China (AQSIQ) on May 30th, 2005, and putinto force in October, 2005. At the same time, the Old Measures issued on July 3rd, 1998 has beenabolished.展开更多
The question was on the mind of every NBA fan last January: Whocould possibly be the next Michael Jordan? Turns out the answer wasn t thenew MJ after all. It was the old Tim Duncan. That s old as in... "old schoo...The question was on the mind of every NBA fan last January: Whocould possibly be the next Michael Jordan? Turns out the answer wasn t thenew MJ after all. It was the old Tim Duncan. That s old as in... "old school." Duncan s game is built on solidfundamentals, hard work and team play. Just as Doctor Naismith intended. Of course, so was Jordan s game. MJ just preferred to play above therim for the first half-dozen years of his career. before he figured out the展开更多
The P300, an endogenous subcomponent of the event-related potential, is thought to reflect cognitive processes. The event-related potential evoked by the old-new memory recognition task in the oddball paradigm is suit...The P300, an endogenous subcomponent of the event-related potential, is thought to reflect cognitive processes. The event-related potential evoked by the old-new memory recognition task in the oddball paradigm is suitable for examining the neural processes involved in malingered neurocognitive deficits. Forty-four undergraduates were randomly assigned to a simulated malingering group and a truth-telling group, Another 22 patients with head injudes were enrolled as a control group. All participants completed the old-new memory recognition task in the oddball paradigm. The mean P300 amplitude of the simulated malingering group was significantly reduced compared with the truth-telling group (P 〈 0.01), but was increased compared with the control group (P〈 0.01). These results revealed that the P300, evoked by the old-new memory recognition task of the oddball paradigm, may be a helpful indicator for determining cognitive malingering.展开更多
This paper uses the panel data of 17 cities in Shandong Province from 2003 to 2018 to construct a panel model to empirically study the impact of foreign direct investment(FDI)on the industrial structure.The results sh...This paper uses the panel data of 17 cities in Shandong Province from 2003 to 2018 to construct a panel model to empirically study the impact of foreign direct investment(FDI)on the industrial structure.The results show that two-way investment,financial industry development,and policy variables have significant roles in promoting the advancement of the industrial structure in the province.In the future implementation of the“Going Global”strategy in Shandong Province,the cooperation between two-way investment and the financial industry should be strengthened,the level of regional financial development should be improved,and the impact of two-way investment on the optimization and upgrading of the industrial structure should be reinforced.展开更多
The new urbanization is an important carrier of ecological civilization construction, and ecological old-age care is the concrete manifestation of the perfect combination of the two, the proper meaning of the new urba...The new urbanization is an important carrier of ecological civilization construction, and ecological old-age care is the concrete manifestation of the perfect combination of the two, the proper meaning of the new urbanization connotation and an inevitable trend of its development. Based on the analysis of the connotation and relationship between the new urbanization and ecological old-age care, together with the current situation and existing problems of the current nursing institutions and ecological old-age care in Xi'an area, this paper discusses the major issues that should be noticed when constructing the ecological old-age care community in Xi'an and three main construction modes.展开更多
MORE than 10 years ago, the song Come Home As Often As You Can to See Your Parents became popular in China, reminding young people of their obli- gation to set aside their hectic lives and return to their hometowns to...MORE than 10 years ago, the song Come Home As Often As You Can to See Your Parents became popular in China, reminding young people of their obli- gation to set aside their hectic lives and return to their hometowns to visit their aging parents. Today, the idea expressed in this song has been codified in Chinese law.展开更多
Dear editor,The advent of modern molecular mechanism’s approach to disease treatment is highly advancing to mitigate/normalize the symptoms of disease i.e.hyperglycemia by targeting at least eight different pathophys...Dear editor,The advent of modern molecular mechanism’s approach to disease treatment is highly advancing to mitigate/normalize the symptoms of disease i.e.hyperglycemia by targeting at least eight different pathophysiological approaches popularly known as omnious octet[1].Importantly,type 2 diabetes is a展开更多
This paper presents an investigation on attitudes towards old and new buildings in Mount Emei that is a significant cultural national park in China. Questionnaires and interviews were employed to collect data from tho...This paper presents an investigation on attitudes towards old and new buildings in Mount Emei that is a significant cultural national park in China. Questionnaires and interviews were employed to collect data from those whose careers and lives are affected, and were affected, by the buildings. The investigation reveals that people show significantly different attitudes towards the two types of buildings and place more value on old buildings. People particularise their liking for old buildings associated with traditional values, aesthetic quality and conformity to surroundings whereas indicates their disliking for new ones with changed values from tradition to modernity, unsound administrative management and poor respect for surroundings. It is concluded that traditional ideology tends to be well expressed by the old buildings but poorly by new ones. It is accordingly suggested that ideology should be taken more into account in new building projects in Mount Emei.展开更多
Many different types of polarized eukaryotic cells have been shown to segregate synthesis for some protein subpopulations to cytoplasmic domains distant from their nucleus.For neurons,these distances can be tens-to-th...Many different types of polarized eukaryotic cells have been shown to segregate synthesis for some protein subpopulations to cytoplasmic domains distant from their nucleus.For neurons,these distances can be tens-to-thousands fold more than the diameter of the cell body.展开更多
Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3...Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time,展开更多
The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the residen...The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,展开更多
Arginine (2-amino-5-guanidino pentanoic acid) was shown in 1895 by Hedin to be present in the proteins of horn. Metabolic nitrogen balance studies, conducted in 1957 by Rose in human adults and in 1959 by Snyderman an...Arginine (2-amino-5-guanidino pentanoic acid) was shown in 1895 by Hedin to be present in the proteins of horn. Metabolic nitrogen balance studies, conducted in 1957 by Rose in human adults and in 1959 by Snyderman and coworkers in young infants, revealed that a dietary source of this amino acid was not an obligatory requirement for growth and maintenance of nitrogen homeostasis in healthy individuals. Hence, It was initially classified as a non-essential (dispensable) amino acid and, perhaps, for reasons of this classification arginine did not receivc the earlier atteniion it now deserves, in relation to an understanding of the nutritional biochemistry and physiology of its metabolism in humans subjects. However, there is currently a considerable interest in the cellular and tissue functions, as well as clinical, therapeutic significance, of arginine. In this paper we review the multiple functions of arginlne, including its role in the L-arginine-nitric oxide pathway,cellular regeneration, immune function, protein synthesis and protein breakdown. We then consider some in vivo aspects of the physiology of arginine metabolism, which varies greatly among eukaryotes, with particular reference to humans. Against this background, studies of arginine in the nutrition of humans under various pathophysiological conditions are reviewed briefly. Finally, a new, updated concept for the metabolic basis for the 'conditional essentiality' of arginine is proposed展开更多
At present,the grape and cherry industries in Shandong are in the leading position in China and have driven the development of related high-end manufacturing industries such as wine,brandy,preserved fruit processing,f...At present,the grape and cherry industries in Shandong are in the leading position in China and have driven the development of related high-end manufacturing industries such as wine,brandy,preserved fruit processing,fruit juice processing and health products. Therefore,vigorously developing the grape and cherry industries in Shandong Province and carrying out development and innovation are important parts of Shandong Province in responding to the strategy of national new and old kinetic energy conversion. However,currently the germplasm resources preserved in the fruit tree resources banks in China are only 45% of those in the US and 27. 2% of those in the EU. Moreover,the development of fruit trees resources banks in Shandong is relatively backward in China,and there is still no banks related with grape and cherry germplasm resources in Shandong. Therefore,importance can be attached to the agriculture,forestry,and animal husbandry to build germplasm resources banks for grape and cherry industries in Shandong Province. Building the national-level grape and cherry germplasm resources bank in Shandong Province can also promote the utilization of wild and farm germplasm resources in the future; advance the research on the genes related to disease resistance,stress resistance and quality of grapes and cherries; push forward the construction and development of cherry and grape mutants banks. It is conducive to the research on the agronomic traits of grapes and cherries,and can provide the parents resources for planting innovation and improving the quality of grapes and cherries,as well as promote the development and application of molecular markers of grapes and cherries,including the identification of lines and crossbreeding. Thereby,it cannot only promote the industry development,but also achieve the development of cultivation,breeding and basic research in an all-round way and the development of " production,study and research" going side by side.展开更多
文摘The renewal of ancient cities is an important part of the urban renewal work in China.However,there are few studies on the general historical ancient cities at the county level in China,and there is no guidance on the renewal path.Through the practice of the renewal design project of Suining County,Xuzhou City,it makes an exploratory study on the renewal concept and mode.It first interprets the connotation and implementation path of the renewal concept of“endowing the old with the new”.Based on the texture analysis of the ancient city of Suining,it finally determines the design theme that tracing the historical context of the ancient city.Using the renewal techniques such as“extraction-transformationactivation”,through the renewal strategies such as“building new space,shaping new landscape,inheriting new culture and pregnant with new environment”,it realizes the regeneration of urban historical context and meets the needs of residents'modern life,so as to provide reference and guidance for the renovation of general historical ancient cities at the county level in China.
文摘In the context of controlling population development in a planned way,China entered an aging society in the early 21 st century.In this context,how to meet the needs of the elderly care and form an effective elderly care model has become a key problem to be solved urgently by local government departments.With the continuous advancement of the elderly care policy,the community-based elderly care has gradually become the mainstream and is in the stage of vigorous promotion.Taking the Gannan old revolutionary base area in Jiangxi Province as an example,this study puts forward"1+4+X"community-based elderly care model based on the policy system of community-based elderly care,the physical and mental health of the elderly,the material space and the construction of evaluation system,and explores how to promote the application of this community model efficiently in the form of industrialization,so as to drive the economic growth of the Gannan old revolutionary base area,promote the employment development and improve the community-based elderly care service.
文摘Neurotrophins:Neurotrophins are peptides or proteins that are known to regulate neuronal viability,development,and function Beyond synaptic plasticity,neurotrophins protect neurons from apoptosis and also promote neurogenesis to recover neuronal defici even in adulthood.
文摘Shanghai is changing in a big way. Xintiandi-New Heaven and Earth-a development of restoredlow-rise houses called Shikumen, or "stone gate"buildings, stands as a perfect symbol of the newShanghai.
文摘“New Accounts of Old Episodes”is a classic handed down in China,which reflects the personality image and charm of the scholars in the Wei and Jin dynasties with the original ecological narrative technique.The scholars of the Wei and Jin Dynasties were detached,facing the world with an aesthetic attitude beyond secular utilitarianism,etiquette,and real life,establish a graceful social stage of vulgarity,create a unique personality beauty,providing valuable ideological wealth for the cultivation of poetic spirit,poetic dwelling,aesthetic style,transcend personality,and wisdom.
文摘With the development of socialism market economy, the former Bar Code ForCommodity Management Measures (being called Old Measures for short hereafter) issued by the NationalBureau of Quality and Technical Supervision can not adapt to the requirement of managing for barcode for commodity. Therefore, for the purpose of standardize bar code for commodity managementstandard, ensuring its quality, speeding up the application of it in electronic business andcirculating field and accelerating the course of being a well informed country, a new Bar Code ForCommodity Management Measures (New Measures for short) has been issued by the General Administratorof Quality Supervision, Inspection and Quarantine of P.R. China (AQSIQ) on May 30th, 2005, and putinto force in October, 2005. At the same time, the Old Measures issued on July 3rd, 1998 has beenabolished.
文摘The question was on the mind of every NBA fan last January: Whocould possibly be the next Michael Jordan? Turns out the answer wasn t thenew MJ after all. It was the old Tim Duncan. That s old as in... "old school." Duncan s game is built on solidfundamentals, hard work and team play. Just as Doctor Naismith intended. Of course, so was Jordan s game. MJ just preferred to play above therim for the first half-dozen years of his career. before he figured out the
文摘The P300, an endogenous subcomponent of the event-related potential, is thought to reflect cognitive processes. The event-related potential evoked by the old-new memory recognition task in the oddball paradigm is suitable for examining the neural processes involved in malingered neurocognitive deficits. Forty-four undergraduates were randomly assigned to a simulated malingering group and a truth-telling group, Another 22 patients with head injudes were enrolled as a control group. All participants completed the old-new memory recognition task in the oddball paradigm. The mean P300 amplitude of the simulated malingering group was significantly reduced compared with the truth-telling group (P 〈 0.01), but was increased compared with the control group (P〈 0.01). These results revealed that the P300, evoked by the old-new memory recognition task of the oddball paradigm, may be a helpful indicator for determining cognitive malingering.
基金the phased result of the general project“Analysis of the Impact of Shandong Province’s Two-Way Investment on the Transformation and Upgrading of Industrial Structure under the Background of‘High-Quality Development’”and the 2020 Shandong Province Key R&D Program(Soft Science Project)(Project Number:2020RKB01339).
文摘This paper uses the panel data of 17 cities in Shandong Province from 2003 to 2018 to construct a panel model to empirically study the impact of foreign direct investment(FDI)on the industrial structure.The results show that two-way investment,financial industry development,and policy variables have significant roles in promoting the advancement of the industrial structure in the province.In the future implementation of the“Going Global”strategy in Shandong Province,the cooperation between two-way investment and the financial industry should be strengthened,the level of regional financial development should be improved,and the impact of two-way investment on the optimization and upgrading of the industrial structure should be reinforced.
基金supported by the 2016 Special Scientific Research Project of Shaanxi Education Department(Grant No.16JK2129)
文摘The new urbanization is an important carrier of ecological civilization construction, and ecological old-age care is the concrete manifestation of the perfect combination of the two, the proper meaning of the new urbanization connotation and an inevitable trend of its development. Based on the analysis of the connotation and relationship between the new urbanization and ecological old-age care, together with the current situation and existing problems of the current nursing institutions and ecological old-age care in Xi'an area, this paper discusses the major issues that should be noticed when constructing the ecological old-age care community in Xi'an and three main construction modes.
文摘MORE than 10 years ago, the song Come Home As Often As You Can to See Your Parents became popular in China, reminding young people of their obli- gation to set aside their hectic lives and return to their hometowns to visit their aging parents. Today, the idea expressed in this song has been codified in Chinese law.
文摘Dear editor,The advent of modern molecular mechanism’s approach to disease treatment is highly advancing to mitigate/normalize the symptoms of disease i.e.hyperglycemia by targeting at least eight different pathophysiological approaches popularly known as omnious octet[1].Importantly,type 2 diabetes is a
文摘This paper presents an investigation on attitudes towards old and new buildings in Mount Emei that is a significant cultural national park in China. Questionnaires and interviews were employed to collect data from those whose careers and lives are affected, and were affected, by the buildings. The investigation reveals that people show significantly different attitudes towards the two types of buildings and place more value on old buildings. People particularise their liking for old buildings associated with traditional values, aesthetic quality and conformity to surroundings whereas indicates their disliking for new ones with changed values from tradition to modernity, unsound administrative management and poor respect for surroundings. It is concluded that traditional ideology tends to be well expressed by the old buildings but poorly by new ones. It is accordingly suggested that ideology should be taken more into account in new building projects in Mount Emei.
基金supported by funds from National Institutes of Health(P01-NS055976 and R01-NS041596)National Science Foundation(MCB-1020970)+1 种基金Dr.Miriam and Sheldon G.Adelson Medical Research Foundationthe Department of Defense/US Army Medical Research and Development(OR120042)
文摘Many different types of polarized eukaryotic cells have been shown to segregate synthesis for some protein subpopulations to cytoplasmic domains distant from their nucleus.For neurons,these distances can be tens-to-thousands fold more than the diameter of the cell body.
基金supported in part by grants EY01545 and by core grant EY03040the Arnold and Mabel Beckman Foundationan unrestricted grant to the Department of Ophthalmology from Research to Prevent Blindness Inc.,New York,NY
文摘Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time,
基金supported by the Bio&Medical Technology Development Program of the National Research Foundation of Korea(NRF)grant(No.2012M3A9C6049935)the DGIST Convergence Science Center Program(15-BD-04)of the Ministry of Science,ICT and Future Planning of Korea
文摘The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,
文摘Arginine (2-amino-5-guanidino pentanoic acid) was shown in 1895 by Hedin to be present in the proteins of horn. Metabolic nitrogen balance studies, conducted in 1957 by Rose in human adults and in 1959 by Snyderman and coworkers in young infants, revealed that a dietary source of this amino acid was not an obligatory requirement for growth and maintenance of nitrogen homeostasis in healthy individuals. Hence, It was initially classified as a non-essential (dispensable) amino acid and, perhaps, for reasons of this classification arginine did not receivc the earlier atteniion it now deserves, in relation to an understanding of the nutritional biochemistry and physiology of its metabolism in humans subjects. However, there is currently a considerable interest in the cellular and tissue functions, as well as clinical, therapeutic significance, of arginine. In this paper we review the multiple functions of arginlne, including its role in the L-arginine-nitric oxide pathway,cellular regeneration, immune function, protein synthesis and protein breakdown. We then consider some in vivo aspects of the physiology of arginine metabolism, which varies greatly among eukaryotes, with particular reference to humans. Against this background, studies of arginine in the nutrition of humans under various pathophysiological conditions are reviewed briefly. Finally, a new, updated concept for the metabolic basis for the 'conditional essentiality' of arginine is proposed
基金supported by the Agricultural scientific and technological innovation project of Shandong Academy of Agricultural Sciences(CXGC2016D01)Agricultural scientific and technological innovation project of Shandong Academy of Agricultural Sciences-cultivating project for National Natural Science Foundation of China in 2018"identification and function research of Vitis vinifera and Vitis amurensis cold stress response-related micro RNAs"+2 种基金Major Agricultural Application Technology Innovation Project of Shandong Province"Research and Application of Precision Control of Maturation and Product Innovation of Featured Brewing Grape"Major Agricultural Application Technology Innovation Project of Shandong Province"Development of Landmark Wines and Integrated Application of Key Technologies in Shandong Province"Fruit innovation team of modern agricultural industry technology system in Shandong Province-Jinan comprehensive test station(SDAIT-06-21)
文摘At present,the grape and cherry industries in Shandong are in the leading position in China and have driven the development of related high-end manufacturing industries such as wine,brandy,preserved fruit processing,fruit juice processing and health products. Therefore,vigorously developing the grape and cherry industries in Shandong Province and carrying out development and innovation are important parts of Shandong Province in responding to the strategy of national new and old kinetic energy conversion. However,currently the germplasm resources preserved in the fruit tree resources banks in China are only 45% of those in the US and 27. 2% of those in the EU. Moreover,the development of fruit trees resources banks in Shandong is relatively backward in China,and there is still no banks related with grape and cherry germplasm resources in Shandong. Therefore,importance can be attached to the agriculture,forestry,and animal husbandry to build germplasm resources banks for grape and cherry industries in Shandong Province. Building the national-level grape and cherry germplasm resources bank in Shandong Province can also promote the utilization of wild and farm germplasm resources in the future; advance the research on the genes related to disease resistance,stress resistance and quality of grapes and cherries; push forward the construction and development of cherry and grape mutants banks. It is conducive to the research on the agronomic traits of grapes and cherries,and can provide the parents resources for planting innovation and improving the quality of grapes and cherries,as well as promote the development and application of molecular markers of grapes and cherries,including the identification of lines and crossbreeding. Thereby,it cannot only promote the industry development,but also achieve the development of cultivation,breeding and basic research in an all-round way and the development of " production,study and research" going side by side.