AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulati...AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulating the movement of the ocular and the extraocular muscles according to Sherrington’s law. The model with joint bearing was to ensure the flexibility and centripetal rotation of the simulated ball and stepper motor as the driving device. A programmable processor was used to control the motion amplitude of the stepper motor. The size of hole was set at the back of the simulated shell to limit the amount of eye movement. Afterwards, using a 5-point Likert scale, 7 experts evaluated the 3D electric ophthalmotrope’s simulation ability and precision, compared with the traditional anatomical model. In addition, the teaching effectiveness of the 3D electric ophthalmotrope was evaluated at in-class quiz and final exam in a randomized controlled trial. RESULTS: The 3D electric ophthalmotrope could be operated easily to demonstrate the eye movements with motion of different ocular muscles. The experts agreed that the 3D electric ophthalmotrope was different from the traditional model and was easier for students to understand every extraocular muscles’ movement in each evaluation index(P<0.05). Moreover, the results of teaching effectiveness showed that the 3D electric ophthalmotrope were significantly greater than the traditional model both at in-class quiz(P<0.01) and final exam(P<0.05). CONCLUSION: This novel 3D electric ophthalmotrope is better than the traditional model, which can be to improve the ophthalmology teaching effectiveness for students to understand the extraocular muscles’ movement.展开更多
Electrical storm,defined as 3 or more separate episodes of ventricular tachycardia or ventricular fibrillation within 24 hours,carries significant morbidity and mortality.These unstable ventricular arrhythmias have be...Electrical storm,defined as 3 or more separate episodes of ventricular tachycardia or ventricular fibrillation within 24 hours,carries significant morbidity and mortality.These unstable ventricular arrhythmias have been described with a variety of conditions including ischemic heart disease,structural heart disease,and genetic conditions.While implantable cardioverter defibrillator implantation and ablation may be indicated and required,antiarrhythmic medication remains an important adjunctive therapy for these persons.展开更多
An adaptive closed-loop system for spinal cord injury(SCI) repair is designed. It integrates stimulation and recording on 16 pairs of electrodes. Two switches(SAS3 T16/SAS1 T16 X2) fabricated in high-voltage 0.8 μm p...An adaptive closed-loop system for spinal cord injury(SCI) repair is designed. It integrates stimulation and recording on 16 pairs of electrodes. Two switches(SAS3 T16/SAS1 T16 X2) fabricated in high-voltage 0.8 μm process with online re-configurable function are proposed. These two switches are combined with commercial off-the-shelf(COTS) electronics to implement the closed-loop implantable system in compact module. The system includes amplifier for recording neural signals, high-voltage stimulator, power transmission device, central processing module and flexible implantable electrodes. Two customized switches route any electrode to amplifier or stimulator, and nerve stimulation and signal recording are performed through lead wire-driven channels. The entire system is able to operate at up to 28 V, and is a biocompatible package with a volume of 42 mm×35 mm×8 mm. This system solves several problems encountered in implantable devices: low flexibility, negative influence of stimulus artifacts on neural detection and low integration of electrodes.展开更多
目的:构建基于人工智能的高血压性脑出血医疗文本信息自动识别系统,快速识别和分析患者临床信息,高效地输出正确的诊疗方案。方法:基于国内外最新高血压性脑出血诊疗指南,经多位高年资神经外科医生和专业人工智能团队共同讨论,构建基于...目的:构建基于人工智能的高血压性脑出血医疗文本信息自动识别系统,快速识别和分析患者临床信息,高效地输出正确的诊疗方案。方法:基于国内外最新高血压性脑出血诊疗指南,经多位高年资神经外科医生和专业人工智能团队共同讨论,构建基于语言表征模型和专家模块的高血压性脑出血医疗文本信息自动识别及决策系统(即H系统)。随后将收集到的高血压性脑出血病例分为训练集、测试集和验证集,以数据库中病例的真实治疗方案为金标准,先总体评价H系统的准确性,再将其与神经外科医生进行对比,分析H系统的判读效率。结果:在测试集中,H系统所输出的治疗方案的准确率为94.0%(91.5%~96.5%),特异度为91.8%(86.3%~97.3%),灵敏度为95.5%(89.3%~98.2%),曲线下面积(area under the curve,AUC)值为0.936(0.922~0.950)(P=0.000);在验证集中,H系统所输出的治疗方案的准确率为93.3%(89.5%~97.1%),特异度为89.9%(83.4%~96.4%),灵敏度为95.8%(92.3%~99.3%),AUC值为0.928(0.891~0.966)(P=0.000)。在处理同样的70例病例时,H系统用时(334.60±4.46)s,而神经外科医生用时(12 550.28±95.45)s;在50 min内,H系统处理的病例数为(383±3)例,而神经外科医生处理的病例数为(11±4)例。结论:本研究所构建的H系统能够对高血压性脑出血患者的急诊病例进行自动识别和分析,并快速输出准确的诊疗方案,可协助医生对高血压脑出血进行急诊诊疗。展开更多
基金Supported by the National Natural Science Foundation of China (No.30901655)Shaanxi Provincial Key Research and Development Program (No.2018SF-230)
文摘AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulating the movement of the ocular and the extraocular muscles according to Sherrington’s law. The model with joint bearing was to ensure the flexibility and centripetal rotation of the simulated ball and stepper motor as the driving device. A programmable processor was used to control the motion amplitude of the stepper motor. The size of hole was set at the back of the simulated shell to limit the amount of eye movement. Afterwards, using a 5-point Likert scale, 7 experts evaluated the 3D electric ophthalmotrope’s simulation ability and precision, compared with the traditional anatomical model. In addition, the teaching effectiveness of the 3D electric ophthalmotrope was evaluated at in-class quiz and final exam in a randomized controlled trial. RESULTS: The 3D electric ophthalmotrope could be operated easily to demonstrate the eye movements with motion of different ocular muscles. The experts agreed that the 3D electric ophthalmotrope was different from the traditional model and was easier for students to understand every extraocular muscles’ movement in each evaluation index(P<0.05). Moreover, the results of teaching effectiveness showed that the 3D electric ophthalmotrope were significantly greater than the traditional model both at in-class quiz(P<0.01) and final exam(P<0.05). CONCLUSION: This novel 3D electric ophthalmotrope is better than the traditional model, which can be to improve the ophthalmology teaching effectiveness for students to understand the extraocular muscles’ movement.
文摘Electrical storm,defined as 3 or more separate episodes of ventricular tachycardia or ventricular fibrillation within 24 hours,carries significant morbidity and mortality.These unstable ventricular arrhythmias have been described with a variety of conditions including ischemic heart disease,structural heart disease,and genetic conditions.While implantable cardioverter defibrillator implantation and ablation may be indicated and required,antiarrhythmic medication remains an important adjunctive therapy for these persons.
基金Supported by the National Natural Science Foundation of China(No.61474107)the National Key Technologies R&D Program(No.2016YFC0105604)。
文摘An adaptive closed-loop system for spinal cord injury(SCI) repair is designed. It integrates stimulation and recording on 16 pairs of electrodes. Two switches(SAS3 T16/SAS1 T16 X2) fabricated in high-voltage 0.8 μm process with online re-configurable function are proposed. These two switches are combined with commercial off-the-shelf(COTS) electronics to implement the closed-loop implantable system in compact module. The system includes amplifier for recording neural signals, high-voltage stimulator, power transmission device, central processing module and flexible implantable electrodes. Two customized switches route any electrode to amplifier or stimulator, and nerve stimulation and signal recording are performed through lead wire-driven channels. The entire system is able to operate at up to 28 V, and is a biocompatible package with a volume of 42 mm×35 mm×8 mm. This system solves several problems encountered in implantable devices: low flexibility, negative influence of stimulus artifacts on neural detection and low integration of electrodes.
文摘目的:构建基于人工智能的高血压性脑出血医疗文本信息自动识别系统,快速识别和分析患者临床信息,高效地输出正确的诊疗方案。方法:基于国内外最新高血压性脑出血诊疗指南,经多位高年资神经外科医生和专业人工智能团队共同讨论,构建基于语言表征模型和专家模块的高血压性脑出血医疗文本信息自动识别及决策系统(即H系统)。随后将收集到的高血压性脑出血病例分为训练集、测试集和验证集,以数据库中病例的真实治疗方案为金标准,先总体评价H系统的准确性,再将其与神经外科医生进行对比,分析H系统的判读效率。结果:在测试集中,H系统所输出的治疗方案的准确率为94.0%(91.5%~96.5%),特异度为91.8%(86.3%~97.3%),灵敏度为95.5%(89.3%~98.2%),曲线下面积(area under the curve,AUC)值为0.936(0.922~0.950)(P=0.000);在验证集中,H系统所输出的治疗方案的准确率为93.3%(89.5%~97.1%),特异度为89.9%(83.4%~96.4%),灵敏度为95.8%(92.3%~99.3%),AUC值为0.928(0.891~0.966)(P=0.000)。在处理同样的70例病例时,H系统用时(334.60±4.46)s,而神经外科医生用时(12 550.28±95.45)s;在50 min内,H系统处理的病例数为(383±3)例,而神经外科医生处理的病例数为(11±4)例。结论:本研究所构建的H系统能够对高血压性脑出血患者的急诊病例进行自动识别和分析,并快速输出准确的诊疗方案,可协助医生对高血压脑出血进行急诊诊疗。
