Thirty four α-substituted or α, α-disubstituted-( 1-methylcyclohexen-4-yl )methanols and α-substituted or α,α-disubstituted-(4-methylcyclohexyl) methanols weresynthesized. Thirty two of them are new compounds. 1...Thirty four α-substituted or α, α-disubstituted-( 1-methylcyclohexen-4-yl )methanols and α-substituted or α,α-disubstituted-(4-methylcyclohexyl) methanols weresynthesized. Thirty two of them are new compounds. 1H NMR and IR spectra of allthe compounds were determined, MS spectra of some of them were obtained as well.The characteristic odors were evaluated.Keywords Fragrance raw materials,α-Terpineol analogues, Synthesis, Structuredetermination展开更多
In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by ...In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by Birch reduction of 4-substituted anisoles and then acetalization. Seven acetals of 4-trimethylsilylcyclohexanone and their carbon counterparts were synthesized similarly. Structures of all new compounds were determined by MS, IR and ~1H NMR, and their characteristic odors were evaluated as well. The characteristic odors of the acetals formed by 4-substituted-3-cyclohexenone and 1, 2-diols are fruity and woody. The acetals formed from 1, 3-diols are woody, and formed with 1, 4-diols are very faint in odor. Odors of acetals of 4-substituted cyclohexanone are all very weak. As a whole, odors of organosilicon compounds are weaker, but somewhat more delicate than their carbon counter- parts.展开更多
文摘Thirty four α-substituted or α, α-disubstituted-( 1-methylcyclohexen-4-yl )methanols and α-substituted or α,α-disubstituted-(4-methylcyclohexyl) methanols weresynthesized. Thirty two of them are new compounds. 1H NMR and IR spectra of allthe compounds were determined, MS spectra of some of them were obtained as well.The characteristic odors were evaluated.Keywords Fragrance raw materials,α-Terpineol analogues, Synthesis, Structuredetermination
基金Project supported by NSFCNational Laboratory of Elemento-Organic Chemistry.
文摘In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by Birch reduction of 4-substituted anisoles and then acetalization. Seven acetals of 4-trimethylsilylcyclohexanone and their carbon counterparts were synthesized similarly. Structures of all new compounds were determined by MS, IR and ~1H NMR, and their characteristic odors were evaluated as well. The characteristic odors of the acetals formed by 4-substituted-3-cyclohexenone and 1, 2-diols are fruity and woody. The acetals formed from 1, 3-diols are woody, and formed with 1, 4-diols are very faint in odor. Odors of acetals of 4-substituted cyclohexanone are all very weak. As a whole, odors of organosilicon compounds are weaker, but somewhat more delicate than their carbon counter- parts.
