BACKGROUND Limited research has explored the impact of cardiovascular disease(CVD)on healthy life expectancy(HLE)especially in resource-limited areas.This study aimed to investigate the association between CVD and HLE...BACKGROUND Limited research has explored the impact of cardiovascular disease(CVD)on healthy life expectancy(HLE)especially in resource-limited areas.This study aimed to investigate the association between CVD and HLE in Chinese rural population.METHODS This study included 11,994 participants aged 45 years and older from the baseline and follow-up surveys of the Henan rural cohort study.Healthy status was measured via a Visual Analogue Scale.The multistate Markov model was applied to estimate the association between CVD and transitions in health,unhealthiness and death.Gender-specific total life expectancy,HLE and unhealthy life expectancy were calculated by the multistate life table method.RESULTS During a mean follow-up time of 3.85(3.84–3.86)years,there were 588 deaths recorded.For individuals with CVD,the risk of switching from health to unhealthiness status was increased by 71%[hazard ratio(HR)=1.71,95%CI:1.42–2.07],the chance of recovery was reduced by 30%(HR=0.70,95%CI:0.60–0.82).Men aged 45 years without CVD could gain an extra 7.08(4.15–10.01)years of HLE and lose 4.00(1.60–6.40)years of unhealthy life expectancy compared to their peers with CVD,respectively.The corresponding estimates among women were 8.62(5.55–11.68)years and 5.82(2.59–9.04)years,respectively.CONCLUSIONS This study indicated that CVD was significantly associated with poorer health status and lower HLE among Chinese rural population.It is an important public health policy to adopt targeted measures to reduce the CVD burden and enhance the quality of life and HLE in resource-limited areas.展开更多
Introduction: The use of foods containing high levels of sugar is increasing all the time. This is a risk factor for increased incidence of type 2 diabetes. There are few studies that have investigated the availabilit...Introduction: The use of foods containing high levels of sugar is increasing all the time. This is a risk factor for increased incidence of type 2 diabetes. There are few studies that have investigated the availability of low-sugar müsli products in grocery stores. Purpose: The study aims to identify which types of müsli contain high respectively low levels of sugar, and which brands are involved. Methods: The material consists of both qualitative interviews and observations from five grocery stores: City Gross, Hemköp, Ica Maxi, Stora Coop and Willy’s in Helsingborg, Sweden. The qualitative interviews had a semi-structured character and were recorded. The interviews took approx. 20 minutes and a textual analysis was conducted of the results. Data from observation was analyzed based on brand, nutritional composition and flavors, and also, where low sugar products were placed on store shelves. Results: The grocery stores provided together brands from AXA, Coop, Finax, Frebaco, Garant, ICA, Risenta, Saltå Kvarn och Urtekram, in total 24 müsli products. Of these products, 19 were high in sugar. The observation reveals that müsli products with high sugar content (17 - 29 g per 100 g müsli) are more prominently displayed than those with low sugar content. From the interviews with the store managers, it became clear that it would be valuable to highlight healthy müsli products on the shelves. However, central bureaucracy puts obstacles to such measures. Discussion: The study emphasizes the need for increased visibility of low-sugar products and proposes solutions such as negotiating with responsible person at the head office in Stockholm. Several reviews have shown that if the grocery store raises the prices of unhealthy food, the consumer is willing to purchase healthier müsli and other products. Conclusion: This study shows the need for grocery stores to upgrade healthy müsli products along with advertising to be able to influence customer’s shopping habits. Also, further research is needed how type 2 diabetes is affected by high intakes of food products with high sugar content.展开更多
As we are facing an aging society,anti-aging strategies have been pursued to reduce the negative impacts of aging and increase the health span of human beings.Gut microbiota has become a key factor in the anti-aging p...As we are facing an aging society,anti-aging strategies have been pursued to reduce the negative impacts of aging and increase the health span of human beings.Gut microbiota has become a key factor in the anti-aging process.Modulation of gut microbiota by fecal microbiota transplantation(FMT)to prevent frailty and unhealthy aging has been a hot topic of research.This narrative review summarizes the benefits of FMT for health span and lifespan,brains,eyes,productive systems,bones,and others.The mechanisms of FMT in improving healthy aging are discussed.The increased beneficial bacteria and decreased pathological bacteria decreased gut permeability and systemic inflammation,increased short-chain fatty acid(SCFA)and SCFA-producing bacteria,and other factors are listed as mechanisms of FMT to improve healthy aging.The points that need to be considered to ensure the optimal outcomes of FMT are also discussed,such as recipients’age,sex,genetic background,and gut microbiota after FMT.Although thisfield is still in its infancy,it has shown that FMT has great potential to improve healthy aging.展开更多
Objective:To evaluate the basic appearance and variation of the venous sinuses and veins in healthy individuals.Methods:Prospectively-recruited healthy volunteers completed a questionnaire and underwent magnetic reson...Objective:To evaluate the basic appearance and variation of the venous sinuses and veins in healthy individuals.Methods:Prospectively-recruited healthy volunteers completed a questionnaire and underwent magnetic resonance imaging plus contrast-enhanced magnetic resonance venography(CE-MRV)to measure their sinus diameters.Anatomical variations of cerebral venous sinuses were evaluated.Results:Fifty-eight individuals were included.The mean diameter of the left transverse sinus(LTS)(5.37±1.35 mm)was significantly smaller than that of the right transverse sinus(RTS)(6.65±1.57 mm)(P<0.001),and the average discrepancy was 19.2%.RTS dominance was noted in 55.1%of cases.Four superior sagittal sinus(SSS)anatomical variations were found.Type A was the most common and was present in 43 participants(74.1%).The SSS preferentially drained into the RTS in 32 patients(55.2%),and arachnoid granulation was observed in the transverse sinus(TS)and SSS in patients.According to our reclassification combined with Osborn’s previous research,we found that the SSS commonly drained into the RTS and that the straight sinus(StS)branched into both TSs.Conclusions:A 19%difference between the LTS and RTS provides a threshold for TS lateral dominance instead of a TS abnormality.Clinicians and radiologists should not ignore the influence of acquired pathology when the SSS drains in a non-RTS-dominant manner.Anatomical variations of the torcular herophili are frequent;the most commonly observed was the StS branching into both TSs,with the SSS draining into the RTS.展开更多
The aim of this study was to verify the existence of business and strategic intelligence policies at the level of Congolese companies and at the state level, likely to foster progress and healthy development in the ea...The aim of this study was to verify the existence of business and strategic intelligence policies at the level of Congolese companies and at the state level, likely to foster progress and healthy development in the east of the DRC. The study was based on a mixed perspective consisting of objective analysis of quantitative data and interpretative analysis of qualitative data. The results showed that business and strategic intelligence policies have not been established at either company or state level, as this is an area of activity that is not known to the players in companies and public departments, and there are no units or offices in their organizational structures responsible for managing strategic information for competitiveness on the international market. In addition, there is a real need to establish strategic information management units within companies, upstream, and to set up a national strategic information management department or agency to help local companies compete in the marketplace, downstream. This reflects the importance and timeliness of building business and strategic intelligence policies to ensure economic progress and development in the eastern DRC. Business and strategic intelligence provides companies with an appropriate tool for researching, collecting, processing and disseminating information useful for decision-making among stakeholders, in order to cope with a crisis or competitive situation. The study suggests a number of key recommendations based on its findings. To the government, it is recommended to establish the national policy of business and strategic intelligence by setting up a national agency of strategic intelligence in favor of local companies;and to companies to establish business intelligence units in their organizational structures in favor of stakeholders to foster advantageous decision-making in the competitive market and achieve progress. Finally, the study suggests that studies be carried out to fully understand the opportunities and impact of business and strategic intelligence in African countries, particularly in the DRC.展开更多
Nursing students have uniqueness within the general university student population as they are among the primary practitioners of the “Healthy China Strategy 2030” and guardians of people’s health. Innovating and st...Nursing students have uniqueness within the general university student population as they are among the primary practitioners of the “Healthy China Strategy 2030” and guardians of people’s health. Innovating and strengthening ideological and political education for nursing students, enhancing their skills in serving the people, is a significant political task for medical universities. Against the backdrop of the “Healthy China Strategy,” how to effectively improve nursing students’ professional competencies, integrate life education, medical humanities education, and general ideological and political education, and utilize life education to construct a more suitable ideological and political education system for nursing students, in order to better establish correct worldviews, values, and professional outlooks, are urgent practical issues that need to be addressed in ideological and political education in medical universities. This article takes life education as an entry point and focuses on integrating it with the internalization and unification of ideological and political education courses, aiming to explore the possibilities and new pathways for integrating life education into the ideological and political education of nursing students in the new era.展开更多
Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data stud...Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.展开更多
Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed...Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.展开更多
Diet education can expand children’s life experience,cultivate good living habits,and develop their character,contributing to the construction of a healthy China.Developing diet education helps children improve their...Diet education can expand children’s life experience,cultivate good living habits,and develop their character,contributing to the construction of a healthy China.Developing diet education helps children improve their health awareness and enables them to form healthy eating behaviors and lifestyles,laying the foundation for their healthy growth and lifelong development.It is not just about disseminating nutrition knowledge but also involves the integration of health education,labor education,and family education through practical experiences.This study analyzes the importance of promoting diet education for children and proposes four promotion strategies that draw on families,schools,relevant departments,and social groups,as well as pilot projects.The application of these strategies will help enhance the effectiveness of diet education and enable children to form healthy eating habits and develop the basic ability to maintain their health.展开更多
Basic medicine is the foundation of basic knowledge of medical science,life science,and natural science,and is the basis for training medical talents.It can help students correctly understand the relationship between ...Basic medicine is the foundation of basic knowledge of medical science,life science,and natural science,and is the basis for training medical talents.It can help students correctly understand the relationship between disease and health,and is of great significance under the perspective of the Healthy China strategy.However,there are still some deficiencies in the current teaching,and insufficient attention has been paid to civics and politics.Thus,it is necessary to carry out curriculum reform in order to enable students to better understand medical knowledge and master medical skills,to ensure the development of medical education,and to play an important role in basic medicine.This study combines the necessity of curriculum reform under the perspective of civics and politics and puts forward a teaching reform strategy suitable for the development of contemporary medicine to provide a direction for the educational development of basic medicine.展开更多
This topic is closely centered on exploring how Chinese fine arts can take the road to the healthy development of art,which is of great guiding significance.It is clear that the road of national art development is to ...This topic is closely centered on exploring how Chinese fine arts can take the road to the healthy development of art,which is of great guiding significance.It is clear that the road of national art development is to carry forward the main theme,promote social justice,guide and infect people with correct public opinion,and better serve the people with excellent works.展开更多
Background: A balanced diet with a low glycemic index (GI) plays an important role in controlling and managing type 2 diabetes mellitus (T2DM). Here, we compared the GI of 2 flavors (vanilla and chocolate) of diabetes...Background: A balanced diet with a low glycemic index (GI) plays an important role in controlling and managing type 2 diabetes mellitus (T2DM). Here, we compared the GI of 2 flavors (vanilla and chocolate) of diabetes-specific nutritional (DSN) supplements to its comparator in healthy Indian adults under fasting conditions. Methods: This study was a 39-day open-label, non-comparative, single-center trial involving healthy adults aged between 18 to 45 years. The subjects received equal doses of 2 DSN powder (Treatments A and B), the comparator product (Treatment C), and dextrose monohydrate as a reference (Treatment R). Doses were administered as per the dosing schedule, after an overnight fast for 10 hours, with 2 intervening non-dosing days. Blood samples were collected on the dosing days to assess changes in capillary blood glucose levels. The primary endpoint of the study was the mean GI of Treatments A, B, and C (Defined as low: GI ≤ 55;medium: 55 GI ≤ 70;High: GI > 70), generated using the incremental area under the curve (AUC<sub>i</sub>) methodology. Safety was assessed throughout the study. Values of all study parameters were represented in ±SD or standard deviation. Results: Fourteen adult male subjects with a mean age of 29.42 ± 4.46 years, and a body mass index of 22.0 ± 1.95 Kg/m<sup>2</sup>, were enrolled in the study. The mean AUC<sub>i</sub> for treatments A, B, and C were 104 ± 10, 111 ± 12, and 87 ± 12 mmol min/L, respectively and for Treatment R it was 276 ± 16, 319 ± 28 and 338 ± 25 mmol min/L for Days 1, 6 and 8, respectively. The mean GI of Treatment A was 33 ± 3, Treatment B was 35 ± 3 and Treatment C was 29 ± 5;all GI means were ≤55. Mild adverse events were reported in 2 (14.3%) subjects. No serious adverse events or deaths were reported in the study. All treatments were well tolerated by the subjects. Conclusion: The glycemic index of both test products and comparator was low (i.e., GI 55) as per ISO 26642:2010 standard.展开更多
On September 15, 2023, the Beijing National Healthy Lifestyle Month promotion event was held at the Juyongguan Great Wall. The event is themed“Three Reduction, Three Healthy Conditions, Starting with Me”, hosted by ...On September 15, 2023, the Beijing National Healthy Lifestyle Month promotion event was held at the Juyongguan Great Wall. The event is themed“Three Reduction, Three Healthy Conditions, Starting with Me”, hosted by the Beijing Municipal Health Commission, and organized by the Beijing Center for Disease Prevention and Control and the Changping District Health Commission.展开更多
In order to advance the construction of a Healthy China and prioritize the health of the people in development strategies,the“2023 China Tumor Prevention and Control Conference”was held in Beijing from October 13th ...In order to advance the construction of a Healthy China and prioritize the health of the people in development strategies,the“2023 China Tumor Prevention and Control Conference”was held in Beijing from October 13th to 15th,2023,hosted by the Chinese Preventive Medicine Association(CPMA)and organized by the Tumor Prevention and Control Professional Committee of the CPMA.展开更多
1 Scope This standard specifies the standard,and evaluation implementation and evaluation criteria for healthy Chinese older adults.This standard is applicable to the evaluation of the health status for Chinese older ...1 Scope This standard specifies the standard,and evaluation implementation and evaluation criteria for healthy Chinese older adults.This standard is applicable to the evaluation of the health status for Chinese older adults aged 60 years and above by the personnel from medical and health institutions,nursing home,etc.展开更多
Background: Although handgrip strength is a biomarker for morbidity/mor-tality, there is lack of evidence on the effects of resistance training on handgrip strength in healthy adults of all ages. Objective: The aim of...Background: Although handgrip strength is a biomarker for morbidity/mor-tality, there is lack of evidence on the effects of resistance training on handgrip strength in healthy adults of all ages. Objective: The aim of this systematic review was to assess the impact of resistance training on handgrip strength in healthy adults. Methods: Five databases/search engines were searched. Studies comparing different types of resistance exercise interventions versus a non-exercised control group on handgrip strength were included. The available data did not allow us to conduct the pre-planned meta-analyses;therefore, only descriptive statistics were performed to summarize the data. Results: Twenty studies (17 randomized and three non-randomized controlled trials) were included, most of which were conducted in older adults. Twelve studies reported no significant difference in the change in handgrip strength between the resistance training and control groups. Two studies showed increases in handgrip strength in the resistance training group compared with the control group. Other studies included results for multi-training groups or left/right hands and found increasing handgrip strength compared to controls, but only in one training group or one hand. Overall, the randomized and non-ran-domized clinical trials presented moderate risk of bias. Conclusions: Due to the lack of low risk-of-bias randomized controlled trials of young and middle-aged adults, different training protocols, and small sample sizes, the existing evidence appears insufficient to support resistance training for increasing handgrip strength in healthy adults. Future studies may seek to discern the optimal way to develop and employ resistance training to improve hand-grip strength.展开更多
According to BBC News,online hate speech increased by 20%during the COVID-19 pandemic.Hate speech from anonymous users can result in psychological harm,including depression and trauma,and can even lead to suicide.Mali...According to BBC News,online hate speech increased by 20%during the COVID-19 pandemic.Hate speech from anonymous users can result in psychological harm,including depression and trauma,and can even lead to suicide.Malicious online comments are increasingly becoming a social and cultural problem.It is therefore critical to detect such comments at the national level and detect malicious users at the corporate level.To achieve a healthy and safe Internet environment,studies should focus on institutional and technical topics.The detection of toxic comments can create a safe online environment.In this study,to detect malicious comments,we used approxi-mately 9,400 examples of hate speech from a Korean corpus of entertainment news comments.We developed toxic comment classification models using supervised learning algorithms,including decision trees,random forest,a support vector machine,and K-nearest neighbors.The proposed model uses random forests to classify toxic words,achieving an F1-score of 0.94.We analyzed the trained model using the permutation feature importance,which is an explanatory machine learning method.Our experimental results confirmed that the toxic comment classifier properly classified hate words used in Korea.Using this research methodology,the proposed method can create a healthy Internet environment by detecting malicious comments written in Korean.展开更多
Background: Spontaneous bilateral pneumothorax in healthy young adults is a rare and challenging condition that defies conventional diagnostic and etiological paradigms. This case report explores the presentation, dia...Background: Spontaneous bilateral pneumothorax in healthy young adults is a rare and challenging condition that defies conventional diagnostic and etiological paradigms. This case report explores the presentation, diagnostic evaluation, management, and potential contributing factors in a 29-year-old male with no prior medical history who experienced bilateral spontaneous pneumothoraces. Aim: This case report aims to shed light on the complexities of managing spontaneous bilateral pneumothorax, particularly in the absence of common risk factors. It underscores the need for a thorough assessment and ongoing research to unravel the enigma surrounding this condition. Case Presentation: A healthy 29-year-old male presented with acute chest pain and shortness of breath, ultimately diagnosed with bilateral spontaneous pneumothoraces. Despite the absence of typical risk factors, advanced imaging techniques revealed valuable insights into the diagnosis and management of this unique presentation. Conclusion: Spontaneous bilateral pneumothorax in healthy individuals presents diagnostic challenges and raises questions about potential genetic predisposition, connective tissue disorders, and lifestyle-related triggers. While the acute phase was effectively managed, this case underscores the importance of interdisciplinary collaboration and ongoing research to comprehensively understand this condition.展开更多
Wetlands are widely distributed all over the world,and have many wildlife resources,which are the main pieces of the puzzle for natural resource conservation and sustainable development on earth and have important irr...Wetlands are widely distributed all over the world,and have many wildlife resources,which are the main pieces of the puzzle for natural resource conservation and sustainable development on earth and have important irreplaceability.In this paper,through questionnaire survey,field research,literature review,etc.,importance weight analysis was conducted by using principal component analysis,and field survey and questionnaire were carried out to collect data on ecological environment function,environmental protection function,landscape beautification function,disaster prevention and mitigation function of urban wetlands.The problems in wetland parks of Nanjing were discussed,such as lack of awareness of landscape planning,deficient late management of wetland parks,weak ability of sustainable development,and unreasonable landscape layout and function.Finally,corresponding solutions were proposed,such as adhering to the planning and design of urban wetland parks with green as the base and health as the basis,persisting in the construction of a wetland system with high biodiversity and near-natural characteristics,adhering to the principle of sustainable development,adopting the construction idea of symbiosis and circulation of urban wetland parks,strengthening education and publicity work,and paying attention to the organic combination of system protection and coordinated construction.The research can build a new development direction for the model of urban wetland parks and green healthy cities,and provide theoretical support for urban sustainable construction.展开更多
基金supported by the Philosophy and Social Science Planning Project of Henan Province(No.2020BSH018)the Science and Technology Innovation Team Support Plan of Colleges and Universities in Henan Province(No.21IRTSTHN029)the Foundation of National Key Program of Research and Development of China(No.2016YFC0900803)。
文摘BACKGROUND Limited research has explored the impact of cardiovascular disease(CVD)on healthy life expectancy(HLE)especially in resource-limited areas.This study aimed to investigate the association between CVD and HLE in Chinese rural population.METHODS This study included 11,994 participants aged 45 years and older from the baseline and follow-up surveys of the Henan rural cohort study.Healthy status was measured via a Visual Analogue Scale.The multistate Markov model was applied to estimate the association between CVD and transitions in health,unhealthiness and death.Gender-specific total life expectancy,HLE and unhealthy life expectancy were calculated by the multistate life table method.RESULTS During a mean follow-up time of 3.85(3.84–3.86)years,there were 588 deaths recorded.For individuals with CVD,the risk of switching from health to unhealthiness status was increased by 71%[hazard ratio(HR)=1.71,95%CI:1.42–2.07],the chance of recovery was reduced by 30%(HR=0.70,95%CI:0.60–0.82).Men aged 45 years without CVD could gain an extra 7.08(4.15–10.01)years of HLE and lose 4.00(1.60–6.40)years of unhealthy life expectancy compared to their peers with CVD,respectively.The corresponding estimates among women were 8.62(5.55–11.68)years and 5.82(2.59–9.04)years,respectively.CONCLUSIONS This study indicated that CVD was significantly associated with poorer health status and lower HLE among Chinese rural population.It is an important public health policy to adopt targeted measures to reduce the CVD burden and enhance the quality of life and HLE in resource-limited areas.
文摘Introduction: The use of foods containing high levels of sugar is increasing all the time. This is a risk factor for increased incidence of type 2 diabetes. There are few studies that have investigated the availability of low-sugar müsli products in grocery stores. Purpose: The study aims to identify which types of müsli contain high respectively low levels of sugar, and which brands are involved. Methods: The material consists of both qualitative interviews and observations from five grocery stores: City Gross, Hemköp, Ica Maxi, Stora Coop and Willy’s in Helsingborg, Sweden. The qualitative interviews had a semi-structured character and were recorded. The interviews took approx. 20 minutes and a textual analysis was conducted of the results. Data from observation was analyzed based on brand, nutritional composition and flavors, and also, where low sugar products were placed on store shelves. Results: The grocery stores provided together brands from AXA, Coop, Finax, Frebaco, Garant, ICA, Risenta, Saltå Kvarn och Urtekram, in total 24 müsli products. Of these products, 19 were high in sugar. The observation reveals that müsli products with high sugar content (17 - 29 g per 100 g müsli) are more prominently displayed than those with low sugar content. From the interviews with the store managers, it became clear that it would be valuable to highlight healthy müsli products on the shelves. However, central bureaucracy puts obstacles to such measures. Discussion: The study emphasizes the need for increased visibility of low-sugar products and proposes solutions such as negotiating with responsible person at the head office in Stockholm. Several reviews have shown that if the grocery store raises the prices of unhealthy food, the consumer is willing to purchase healthier müsli and other products. Conclusion: This study shows the need for grocery stores to upgrade healthy müsli products along with advertising to be able to influence customer’s shopping habits. Also, further research is needed how type 2 diabetes is affected by high intakes of food products with high sugar content.
基金This work was sponsored by Natural Science Foundation of Chongqing,China(cstc2021jcyjbshX0176 to Ting Gong)National Natural Science Foundation of China(81900980 to Huifen Ding).
文摘As we are facing an aging society,anti-aging strategies have been pursued to reduce the negative impacts of aging and increase the health span of human beings.Gut microbiota has become a key factor in the anti-aging process.Modulation of gut microbiota by fecal microbiota transplantation(FMT)to prevent frailty and unhealthy aging has been a hot topic of research.This narrative review summarizes the benefits of FMT for health span and lifespan,brains,eyes,productive systems,bones,and others.The mechanisms of FMT in improving healthy aging are discussed.The increased beneficial bacteria and decreased pathological bacteria decreased gut permeability and systemic inflammation,increased short-chain fatty acid(SCFA)and SCFA-producing bacteria,and other factors are listed as mechanisms of FMT to improve healthy aging.The points that need to be considered to ensure the optimal outcomes of FMT are also discussed,such as recipients’age,sex,genetic background,and gut microbiota after FMT.Although thisfield is still in its infancy,it has shown that FMT has great potential to improve healthy aging.
基金supported by the National Natural Science Foundation of China(82027802)the Pharmaceutical Collaboration Project of the Beijing Science and Technology Commission(Z181100001918026)the Talents Gathering Project of Xuanwu Hospital,Capital Medical University.
文摘Objective:To evaluate the basic appearance and variation of the venous sinuses and veins in healthy individuals.Methods:Prospectively-recruited healthy volunteers completed a questionnaire and underwent magnetic resonance imaging plus contrast-enhanced magnetic resonance venography(CE-MRV)to measure their sinus diameters.Anatomical variations of cerebral venous sinuses were evaluated.Results:Fifty-eight individuals were included.The mean diameter of the left transverse sinus(LTS)(5.37±1.35 mm)was significantly smaller than that of the right transverse sinus(RTS)(6.65±1.57 mm)(P<0.001),and the average discrepancy was 19.2%.RTS dominance was noted in 55.1%of cases.Four superior sagittal sinus(SSS)anatomical variations were found.Type A was the most common and was present in 43 participants(74.1%).The SSS preferentially drained into the RTS in 32 patients(55.2%),and arachnoid granulation was observed in the transverse sinus(TS)and SSS in patients.According to our reclassification combined with Osborn’s previous research,we found that the SSS commonly drained into the RTS and that the straight sinus(StS)branched into both TSs.Conclusions:A 19%difference between the LTS and RTS provides a threshold for TS lateral dominance instead of a TS abnormality.Clinicians and radiologists should not ignore the influence of acquired pathology when the SSS drains in a non-RTS-dominant manner.Anatomical variations of the torcular herophili are frequent;the most commonly observed was the StS branching into both TSs,with the SSS draining into the RTS.
文摘The aim of this study was to verify the existence of business and strategic intelligence policies at the level of Congolese companies and at the state level, likely to foster progress and healthy development in the east of the DRC. The study was based on a mixed perspective consisting of objective analysis of quantitative data and interpretative analysis of qualitative data. The results showed that business and strategic intelligence policies have not been established at either company or state level, as this is an area of activity that is not known to the players in companies and public departments, and there are no units or offices in their organizational structures responsible for managing strategic information for competitiveness on the international market. In addition, there is a real need to establish strategic information management units within companies, upstream, and to set up a national strategic information management department or agency to help local companies compete in the marketplace, downstream. This reflects the importance and timeliness of building business and strategic intelligence policies to ensure economic progress and development in the eastern DRC. Business and strategic intelligence provides companies with an appropriate tool for researching, collecting, processing and disseminating information useful for decision-making among stakeholders, in order to cope with a crisis or competitive situation. The study suggests a number of key recommendations based on its findings. To the government, it is recommended to establish the national policy of business and strategic intelligence by setting up a national agency of strategic intelligence in favor of local companies;and to companies to establish business intelligence units in their organizational structures in favor of stakeholders to foster advantageous decision-making in the competitive market and achieve progress. Finally, the study suggests that studies be carried out to fully understand the opportunities and impact of business and strategic intelligence in African countries, particularly in the DRC.
文摘Nursing students have uniqueness within the general university student population as they are among the primary practitioners of the “Healthy China Strategy 2030” and guardians of people’s health. Innovating and strengthening ideological and political education for nursing students, enhancing their skills in serving the people, is a significant political task for medical universities. Against the backdrop of the “Healthy China Strategy,” how to effectively improve nursing students’ professional competencies, integrate life education, medical humanities education, and general ideological and political education, and utilize life education to construct a more suitable ideological and political education system for nursing students, in order to better establish correct worldviews, values, and professional outlooks, are urgent practical issues that need to be addressed in ideological and political education in medical universities. This article takes life education as an entry point and focuses on integrating it with the internalization and unification of ideological and political education courses, aiming to explore the possibilities and new pathways for integrating life education into the ideological and political education of nursing students in the new era.
文摘Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.
文摘Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.
基金Research and Practice Project on Educational Reform of Xinxiang Medical University(2024-XYJG-35)Open Research Project of Henan Provincial Key Medicine Laboratory of Nursing(HNSYHLKT202303)Higher Education Research Project of Henan Association of Higher Education(2021SXHLX175)。
文摘Diet education can expand children’s life experience,cultivate good living habits,and develop their character,contributing to the construction of a healthy China.Developing diet education helps children improve their health awareness and enables them to form healthy eating behaviors and lifestyles,laying the foundation for their healthy growth and lifelong development.It is not just about disseminating nutrition knowledge but also involves the integration of health education,labor education,and family education through practical experiences.This study analyzes the importance of promoting diet education for children and proposes four promotion strategies that draw on families,schools,relevant departments,and social groups,as well as pilot projects.The application of these strategies will help enhance the effectiveness of diet education and enable children to form healthy eating habits and develop the basic ability to maintain their health.
基金Key Project of Heilongjiang Provincial Education Science“14th Five-Year Plan”2022(GJB1422701)General Project of Educational Teaching Reform of Jiamusi University in Heilongjiang Province(2021JY1-06)+1 种基金Key Project of Heilongjiang Provincial Education Science“14th Five-Year Plan”2021(GJB1421168)Key Project of Heilongjiang Provincial Education Science“14th Five-Year Plan”2022(GJB1422698)。
文摘Basic medicine is the foundation of basic knowledge of medical science,life science,and natural science,and is the basis for training medical talents.It can help students correctly understand the relationship between disease and health,and is of great significance under the perspective of the Healthy China strategy.However,there are still some deficiencies in the current teaching,and insufficient attention has been paid to civics and politics.Thus,it is necessary to carry out curriculum reform in order to enable students to better understand medical knowledge and master medical skills,to ensure the development of medical education,and to play an important role in basic medicine.This study combines the necessity of curriculum reform under the perspective of civics and politics and puts forward a teaching reform strategy suitable for the development of contemporary medicine to provide a direction for the educational development of basic medicine.
文摘This topic is closely centered on exploring how Chinese fine arts can take the road to the healthy development of art,which is of great guiding significance.It is clear that the road of national art development is to carry forward the main theme,promote social justice,guide and infect people with correct public opinion,and better serve the people with excellent works.
文摘Background: A balanced diet with a low glycemic index (GI) plays an important role in controlling and managing type 2 diabetes mellitus (T2DM). Here, we compared the GI of 2 flavors (vanilla and chocolate) of diabetes-specific nutritional (DSN) supplements to its comparator in healthy Indian adults under fasting conditions. Methods: This study was a 39-day open-label, non-comparative, single-center trial involving healthy adults aged between 18 to 45 years. The subjects received equal doses of 2 DSN powder (Treatments A and B), the comparator product (Treatment C), and dextrose monohydrate as a reference (Treatment R). Doses were administered as per the dosing schedule, after an overnight fast for 10 hours, with 2 intervening non-dosing days. Blood samples were collected on the dosing days to assess changes in capillary blood glucose levels. The primary endpoint of the study was the mean GI of Treatments A, B, and C (Defined as low: GI ≤ 55;medium: 55 GI ≤ 70;High: GI > 70), generated using the incremental area under the curve (AUC<sub>i</sub>) methodology. Safety was assessed throughout the study. Values of all study parameters were represented in ±SD or standard deviation. Results: Fourteen adult male subjects with a mean age of 29.42 ± 4.46 years, and a body mass index of 22.0 ± 1.95 Kg/m<sup>2</sup>, were enrolled in the study. The mean AUC<sub>i</sub> for treatments A, B, and C were 104 ± 10, 111 ± 12, and 87 ± 12 mmol min/L, respectively and for Treatment R it was 276 ± 16, 319 ± 28 and 338 ± 25 mmol min/L for Days 1, 6 and 8, respectively. The mean GI of Treatment A was 33 ± 3, Treatment B was 35 ± 3 and Treatment C was 29 ± 5;all GI means were ≤55. Mild adverse events were reported in 2 (14.3%) subjects. No serious adverse events or deaths were reported in the study. All treatments were well tolerated by the subjects. Conclusion: The glycemic index of both test products and comparator was low (i.e., GI 55) as per ISO 26642:2010 standard.
文摘On September 15, 2023, the Beijing National Healthy Lifestyle Month promotion event was held at the Juyongguan Great Wall. The event is themed“Three Reduction, Three Healthy Conditions, Starting with Me”, hosted by the Beijing Municipal Health Commission, and organized by the Beijing Center for Disease Prevention and Control and the Changping District Health Commission.
文摘In order to advance the construction of a Healthy China and prioritize the health of the people in development strategies,the“2023 China Tumor Prevention and Control Conference”was held in Beijing from October 13th to 15th,2023,hosted by the Chinese Preventive Medicine Association(CPMA)and organized by the Tumor Prevention and Control Professional Committee of the CPMA.
文摘1 Scope This standard specifies the standard,and evaluation implementation and evaluation criteria for healthy Chinese older adults.This standard is applicable to the evaluation of the health status for Chinese older adults aged 60 years and above by the personnel from medical and health institutions,nursing home,etc.
文摘Background: Although handgrip strength is a biomarker for morbidity/mor-tality, there is lack of evidence on the effects of resistance training on handgrip strength in healthy adults of all ages. Objective: The aim of this systematic review was to assess the impact of resistance training on handgrip strength in healthy adults. Methods: Five databases/search engines were searched. Studies comparing different types of resistance exercise interventions versus a non-exercised control group on handgrip strength were included. The available data did not allow us to conduct the pre-planned meta-analyses;therefore, only descriptive statistics were performed to summarize the data. Results: Twenty studies (17 randomized and three non-randomized controlled trials) were included, most of which were conducted in older adults. Twelve studies reported no significant difference in the change in handgrip strength between the resistance training and control groups. Two studies showed increases in handgrip strength in the resistance training group compared with the control group. Other studies included results for multi-training groups or left/right hands and found increasing handgrip strength compared to controls, but only in one training group or one hand. Overall, the randomized and non-ran-domized clinical trials presented moderate risk of bias. Conclusions: Due to the lack of low risk-of-bias randomized controlled trials of young and middle-aged adults, different training protocols, and small sample sizes, the existing evidence appears insufficient to support resistance training for increasing handgrip strength in healthy adults. Future studies may seek to discern the optimal way to develop and employ resistance training to improve hand-grip strength.
文摘According to BBC News,online hate speech increased by 20%during the COVID-19 pandemic.Hate speech from anonymous users can result in psychological harm,including depression and trauma,and can even lead to suicide.Malicious online comments are increasingly becoming a social and cultural problem.It is therefore critical to detect such comments at the national level and detect malicious users at the corporate level.To achieve a healthy and safe Internet environment,studies should focus on institutional and technical topics.The detection of toxic comments can create a safe online environment.In this study,to detect malicious comments,we used approxi-mately 9,400 examples of hate speech from a Korean corpus of entertainment news comments.We developed toxic comment classification models using supervised learning algorithms,including decision trees,random forest,a support vector machine,and K-nearest neighbors.The proposed model uses random forests to classify toxic words,achieving an F1-score of 0.94.We analyzed the trained model using the permutation feature importance,which is an explanatory machine learning method.Our experimental results confirmed that the toxic comment classifier properly classified hate words used in Korea.Using this research methodology,the proposed method can create a healthy Internet environment by detecting malicious comments written in Korean.
文摘Background: Spontaneous bilateral pneumothorax in healthy young adults is a rare and challenging condition that defies conventional diagnostic and etiological paradigms. This case report explores the presentation, diagnostic evaluation, management, and potential contributing factors in a 29-year-old male with no prior medical history who experienced bilateral spontaneous pneumothoraces. Aim: This case report aims to shed light on the complexities of managing spontaneous bilateral pneumothorax, particularly in the absence of common risk factors. It underscores the need for a thorough assessment and ongoing research to unravel the enigma surrounding this condition. Case Presentation: A healthy 29-year-old male presented with acute chest pain and shortness of breath, ultimately diagnosed with bilateral spontaneous pneumothoraces. Despite the absence of typical risk factors, advanced imaging techniques revealed valuable insights into the diagnosis and management of this unique presentation. Conclusion: Spontaneous bilateral pneumothorax in healthy individuals presents diagnostic challenges and raises questions about potential genetic predisposition, connective tissue disorders, and lifestyle-related triggers. While the acute phase was effectively managed, this case underscores the importance of interdisciplinary collaboration and ongoing research to comprehensively understand this condition.
基金the Innovation Training Planning Project for College Students in Anhui Province(AH202112216134)Key Project of Scientific Research Project of Higher Education of Anhui Province(Natural Science)(2022AH051861)+1 种基金Scientific Research Team Project of Anhui Xinhua University(kytd202202)Key Laboratory Project of Building Structure of General Universities in Anhui Province(KLBSZD202105).
文摘Wetlands are widely distributed all over the world,and have many wildlife resources,which are the main pieces of the puzzle for natural resource conservation and sustainable development on earth and have important irreplaceability.In this paper,through questionnaire survey,field research,literature review,etc.,importance weight analysis was conducted by using principal component analysis,and field survey and questionnaire were carried out to collect data on ecological environment function,environmental protection function,landscape beautification function,disaster prevention and mitigation function of urban wetlands.The problems in wetland parks of Nanjing were discussed,such as lack of awareness of landscape planning,deficient late management of wetland parks,weak ability of sustainable development,and unreasonable landscape layout and function.Finally,corresponding solutions were proposed,such as adhering to the planning and design of urban wetland parks with green as the base and health as the basis,persisting in the construction of a wetland system with high biodiversity and near-natural characteristics,adhering to the principle of sustainable development,adopting the construction idea of symbiosis and circulation of urban wetland parks,strengthening education and publicity work,and paying attention to the organic combination of system protection and coordinated construction.The research can build a new development direction for the model of urban wetland parks and green healthy cities,and provide theoretical support for urban sustainable construction.
