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Treatment of stellate ganglion block in diseases:Its role and application prospect 被引量:2
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作者 Jing-Jing Deng Cai-Ling Zhang +4 位作者 Dian-Wen Liu Tao Huang Jian Xu Qing-Yan Liu Yue-Nong Zhang 《World Journal of Clinical Cases》 SCIE 2023年第10期2160-2167,共8页
The stellate ganglion(SG),as a type of sympathetic ganglion,consists of the sixth and seventh cervical vertebrae and the first thoracic sympathetic ganglia.SG block(SGB)is a minimally invasive injection that aims to i... The stellate ganglion(SG),as a type of sympathetic ganglion,consists of the sixth and seventh cervical vertebrae and the first thoracic sympathetic ganglia.SG block(SGB)is a minimally invasive injection that aims to inject low-concentration local anesthetics to induce a broad sympathetic blocking effect near the SG.There have been no changes and progress in the clinical application of SGB since the 1830s due to several potential risks,including hematoma from blood vessel injury,hoarseness from recurrent laryngeal nerve injury,and cardiopulmonary arrest.The feasibility and safety of SGB have greatly improved since the appearance of ultrasound-guided SGB.In recent years,SGB has been widely applied in the field of non-anesthesiology sedation,with significant therapeutic effects on pain,immunological diseases,somnipathy,psychological disorders,arrhythmias,and endocrine diseases.The present study reviews the present application of SGB in clinical practice. 展开更多
关键词 ECHOCARDIOGRAPHY PAIN immunological diseases Somnipathy Psychological disorders ARRHYTHMIAS Endocrine diseases
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Column agglutination technology in immunologic diagnosis of haemolytic disease of the newborn.
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《中国输血杂志》 CAS CSCD 2001年第S1期380-,共1页
关键词 Column agglutination technology in immunologic diagnosis of haemolytic disease of the newborn
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Chronic liver inflammation:Clinical implications beyond alcoholic liver disease 被引量:6
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作者 Byoung-Jin Park Yong-Jae Lee Hye-Ree Lee 《World Journal of Gastroenterology》 SCIE CAS 2014年第9期2168-2175,共8页
Chronic alcohol exposure can lead to alcoholic liver disease, including hepatitis, cirrhosis and hepatocellular carcinoma, and chronic inflammation can simultaneously cause systemic medical illness. Recent evidence su... Chronic alcohol exposure can lead to alcoholic liver disease, including hepatitis, cirrhosis and hepatocellular carcinoma, and chronic inflammation can simultaneously cause systemic medical illness. Recent evidence suggests that alcoholic liver disease is a predictor for liver-related diseases, cardiovascular disease, immunologic disease, and bone disease. Chronic inflammation in alcoholic liver disease is mediated by a direct inflammatory cascade from the alcohol detoxification process and an indirect inflammatory cascade in response to gut microflora-derived lipopolysaccharides (LPS). The pathophysiology of alcoholic liver disease and its related systemic illness is characterized by oxidative stress, activation of the immune cascade, and gut-liver interactions. Integrative therapeutic strategies for alcoholic liver disease include abstaining from alcohol consumption; general anti-inflammatories such as glucocorticoid, pentoxifylline, and tumour necrosis factor-&#x003b1; antagonist; antioxidants such as N- acetylcysteine; gut microflora and LPS modulators such as rifaximin and/or probiotics. This review focuses on the impact of chronic liver inflammation on systemic health problems and several potential therapeutic targets. 展开更多
关键词 Alcoholic liver disease Oxidative stress Cardiovascular disease immunologic disease Bone disease
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Inflammatory bowel disease:definition,epidemiology,etiologic aspects,andimmunogenetic studies 被引量:31
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作者 XIA Bing JBA Crusius +1 位作者 SGM Meuwissen AS Pe a 《World Journal of Gastroenterology》 SCIE CAS CSCD 1998年第5期83-95,共13页
关键词 inflammatory bowel disease/epidemiology inflammatory bowel disease/etiology inflammatory bowel disease/genetics inflammatory bowel disease/immunology
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Current concepts of the pathogenesis of IBD
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《World Journal of Gastroenterology》 SCIE CAS CSCD 1998年第S1期28-30,共3页
Overthepastdecade,thefocusoftheetiopathogenesisofchronicinflammatoryboweldisease(IBD)hasturnedtowarddefining... Overthepastdecade,thefocusoftheetiopathogenesisofchronicinflammatoryboweldisease(IBD)hasturnedtowarddefiningadeficitinimmuner... 展开更多
关键词 INFLAMMATORY BOWEL disease/etiology INFLAMMATORY BOWEL disease/pathology INFLAMMATORY BOWEL disease/immunology Crohn′s disease colitis ULCERATIVE
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Autoimmune hepatitis 被引量:20
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作者 Farhad Sahebjam John M. Vierling 《Frontiers of Medicine》 SCIE CAS CSCD 2015年第2期187-219,共33页
Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte- specific autoantigens. It is characterized by female predilection, elevated aminotransferase levels, autoantibodies... Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte- specific autoantigens. It is characterized by female predilection, elevated aminotransferase levels, autoantibodies, increased y-globulin or IgG levels and biopsy evidence of interface hepatitis. It is currently divided into types 1 and 2, based on expression of autoantibodies. Autoantigenic epitopes have been identified only for the less frequent type 2. Although autoimmune hepatitis occurs in childhood, this review focuses on disease in adults. In the absence of pathognomonic biomarkers, diagnosis requires consideration of clinical, biochemical, serological and histological features, which have been codified into validated diagnostic scoring systems. Since many features also occur in other chronic liver diseases, these scoring systems aid evaluation of the differential diagnosis. New practice guidelines have redefined criteria for remission to include complete biochemical and histological normalization on immunosuppressive therapy. Immunosuppression is most often successful using prednisone or prednisolone and azathioprine; however, the combination of budesonide and azathioprine for non-cirrhotic patients offers distinct advantages. Patients failing standard immunosuppression are candidates for alternative immunosuppressive regimens, yet none of the options has been studied in a randomized, controlled trial. Overlap syndromes with either primary sclerosing cholangitis or primary biliary cirrhosis occur in a minority. Liver transplantation represents a life-saving option for patients presenting with acute liver failure, severely decompensated cirrhosis or hepatocellular carcinoma. Transplant recipients are at risk for recurrent autoimmune hepatitis in the allograft, and de novo disease may occur in patients transplanted for other indications. Patients transplanted for AIH are also at risk for recurrent or de novo inflammatory bowel disease. Progress in our understanding of the immunopathogenesis should lead to identification of specific diagnostic and prognostic biomarkers and new therapeutic strategies. 展开更多
关键词 autoimmune hepatitis AUTOANTIBODIES diagnosis immunological diseases drug-induced liver injury THERAPY IMMUNOSUPPRESSION OUTCOMES hepatocellular carcinoma liver transplantation
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