Introduction:Parallel stent-stent grafting is a major endovascular technique used to preserve the supra-aortic branches during thoracic endovascular aortic repair(TEVAR)of aortic pathologies involving the aortic arch....Introduction:Parallel stent-stent grafting is a major endovascular technique used to preserve the supra-aortic branches during thoracic endovascular aortic repair(TEVAR)of aortic pathologies involving the aortic arch.The short-and mid-term results of this technique are satisfactory;however,endoleak remains a major concern.Thus,here we designed a new chimney stent-graft to decrease the endoleak rate.Aim:To testify the feasibility and safety of the new chimney stent-graft system in a canine model.Material and methods:Six Labrador retrievers were used.Pre-operative data were collected and all operations were performed under general anesthesia.The main and chimney stent-grafts were implanted through the abdominal aorta and left subclavian artery approaches,respectively.Completion digital subtraction angiography(DSA)was performed to confirm the immediate outcomes.All dogs were fed separately for 6 months and sacrificed after aortic angiography.The thoracic aorta and the main and chimney stent-grafts were harvested for histopathologic examination.Results:No complications were found in follow-up DSA.All branch arteries were patent.In?ammatory responses were observed around the stent-grafts in 3 experimental animals,and slight hyperplasia was observed in the surrounding tissues compared with the normal vessels.There was no mural thrombus in the stent,endothelial cells were noted on the inner surface of the stent,and thrombus was formed in the outer skirt and gutter area.The histopathologic examinations revealed similar results to those of gross necropsy observations.Conclusions:This study demonstrated the feasibility and safety of the Longuette stent-graft and the first to report a revised stent-graft specific for chimney technique.展开更多
To make it possible for the thermal wave theory on temperature oscillation (TO) effects in living tissues to be founded on the substantial experimental basis, a series of typical decisive experiments in vivo as well a...To make it possible for the thermal wave theory on temperature oscillation (TO) effects in living tissues to be founded on the substantial experimental basis, a series of typical decisive experiments in vivo as well as in artificially simulating constructions were carried out. Conclusions obtained including some other scholars' animal experimental results all greatly support the thermal wave viewpoint qualitatively.A few experimental facts used hot to be easily understood from the classical viewpoint are also well reinterpreted. The revealing on the thermal wave mechanisms of TO in living tissues is a brand new discovery and deep insight into this important thermophysiological phenomenon. It may possibly promote new investigations on the corresponding topics in the field of bioheat transfer science.展开更多
Wireless capsule endoscopy(CE), an image inspection technique, has been an important advancement in the diagnosis of gastrointestinal(GI) tract diseases. A video capsule endoscopy(VCE) system is analyzed in this study...Wireless capsule endoscopy(CE), an image inspection technique, has been an important advancement in the diagnosis of gastrointestinal(GI) tract diseases. A video capsule endoscopy(VCE) system is analyzed in this study. A complementary metal oxide semiconductor(CMOS) analog image sensor is adopted, and other illumination, communication and energy modules are designed for functional realization. Measuring only φ11 mm ×25 mm, the VCE has a total power consumption of 52.5 m W, which enables it to work continuously for 8 h. The in vivo experiment on a living pig indicates that a clear video with high frame rate of 30 f/s can be obtained.展开更多
文摘Introduction:Parallel stent-stent grafting is a major endovascular technique used to preserve the supra-aortic branches during thoracic endovascular aortic repair(TEVAR)of aortic pathologies involving the aortic arch.The short-and mid-term results of this technique are satisfactory;however,endoleak remains a major concern.Thus,here we designed a new chimney stent-graft to decrease the endoleak rate.Aim:To testify the feasibility and safety of the new chimney stent-graft system in a canine model.Material and methods:Six Labrador retrievers were used.Pre-operative data were collected and all operations were performed under general anesthesia.The main and chimney stent-grafts were implanted through the abdominal aorta and left subclavian artery approaches,respectively.Completion digital subtraction angiography(DSA)was performed to confirm the immediate outcomes.All dogs were fed separately for 6 months and sacrificed after aortic angiography.The thoracic aorta and the main and chimney stent-grafts were harvested for histopathologic examination.Results:No complications were found in follow-up DSA.All branch arteries were patent.In?ammatory responses were observed around the stent-grafts in 3 experimental animals,and slight hyperplasia was observed in the surrounding tissues compared with the normal vessels.There was no mural thrombus in the stent,endothelial cells were noted on the inner surface of the stent,and thrombus was formed in the outer skirt and gutter area.The histopathologic examinations revealed similar results to those of gross necropsy observations.Conclusions:This study demonstrated the feasibility and safety of the Longuette stent-graft and the first to report a revised stent-graft specific for chimney technique.
文摘To make it possible for the thermal wave theory on temperature oscillation (TO) effects in living tissues to be founded on the substantial experimental basis, a series of typical decisive experiments in vivo as well as in artificially simulating constructions were carried out. Conclusions obtained including some other scholars' animal experimental results all greatly support the thermal wave viewpoint qualitatively.A few experimental facts used hot to be easily understood from the classical viewpoint are also well reinterpreted. The revealing on the thermal wave mechanisms of TO in living tissues is a brand new discovery and deep insight into this important thermophysiological phenomenon. It may possibly promote new investigations on the corresponding topics in the field of bioheat transfer science.
基金the National Natural Science Foundation of China(No.31170968)the Shanghai Science Committee Foundation(No.09DZ1907400)
文摘Wireless capsule endoscopy(CE), an image inspection technique, has been an important advancement in the diagnosis of gastrointestinal(GI) tract diseases. A video capsule endoscopy(VCE) system is analyzed in this study. A complementary metal oxide semiconductor(CMOS) analog image sensor is adopted, and other illumination, communication and energy modules are designed for functional realization. Measuring only φ11 mm ×25 mm, the VCE has a total power consumption of 52.5 m W, which enables it to work continuously for 8 h. The in vivo experiment on a living pig indicates that a clear video with high frame rate of 30 f/s can be obtained.
