Objective:To assess outcome indicators in clinical trials and provide a reference for establishing a core outcome set to treat hyperplasia of mammary gland(HMG)with traditional Chinese medicine(TCM).Methods:Eight onli...Objective:To assess outcome indicators in clinical trials and provide a reference for establishing a core outcome set to treat hyperplasia of mammary gland(HMG)with traditional Chinese medicine(TCM).Methods:Eight online databases were searched from their inception to December 31,2022,to assess outcomes reported in randomized controlled trials(RCTs)of HMG treated with TCM.The quality of the included studies was assessed according to the Cochrane Risk of Bias Assessment Tool.All outcomes were extracted,classified,and described.Results:A total of 8249 articles were initially retrieved.Of these,70 articles were eligible and involved 10618 participants with HMG.A total of 17 outcome indicators with a frequency of 271 times were involved and were collected according to six outcome domains.Conclusions:The core outcomes of RCTs of HMG treated with TCM are large and divergent.There are problems in evaluation standards,primary and secondary outcomes,TCM characteristic indicators,long-term prognosis,and standardization of reporting.It is recommended to strengthen the trial design and actively construct the core outcome sets with TCM characteristics for HMG.展开更多
The biggest environmental problem caused by the construction of tunnels adjacent to high-rise buildings is the settlement of buildings.The paper analyzes the influence of tunnel excavation on the deformation of the su...The biggest environmental problem caused by the construction of tunnels adjacent to high-rise buildings is the settlement of buildings.The paper analyzes the influence of tunnel excavation on the deformation of the superstructure and the deformation mode of the superstructure.It introduces the indicators and standards for the construction control of tunnel adjacent to the building at home and abroad.Combined with the Yuzhong tunnel project under construction in Chongqing,the main monitoring indicators and control standards of the Yuzhong Tunnel passing through the main buildings are given after comprehensive analysis and considerations,which provide a reference for the deformation control indicators of similar urban traffic tunnels adjacent to high-rise buildings.展开更多
The air conditioning system in the Umm Al-Qura University (Albdiya Campus) was conceived to be a district cooling by a remote chilled water plant. Recently, there are two chilled water plants in the university install...The air conditioning system in the Umm Al-Qura University (Albdiya Campus) was conceived to be a district cooling by a remote chilled water plant. Recently, there are two chilled water plants in the university installed strategically to provide chilled water to all the academic and administrative buildings of the university through distribution network with total capacity approximately of 12,000 tons of refrigeration. The plants were built based on cooling towers with open water cycle as heat rejection system. Water treatment chemicals has been used to protect the cooling systems from corrosion, scaling and microbiological fouling accompanied with dissolved and suspended water impurities. Different methods are being used to determine and control the treatment chemical concentrations and system performance indicators. Traditional chemical controller has drawback of indirect measurements and set points. The purpose of this paper is to present a solution to overcome the problems of traditional and conventional chemical treatment and control sys-tems. Central cooling plant number (1) assigned to perform experimental setup using new chemical treatment technology. Advanced automatic chemical treatment controller installed on condensers (1, 2 and 3), and certain key performance indicators were selected and monitored such as chemical and water consumption, power, energy saving, and maintaining system integrity and efficiency. Satisfactory results were obtained in terms of performance and cost of operation.展开更多
One of the main problems in the flow-through gas purification technologies is related with continuous control of the outlet gas purity. The information concerning purity of the produced gas is on high demand, e.g., fo...One of the main problems in the flow-through gas purification technologies is related with continuous control of the outlet gas purity. The information concerning purity of the produced gas is on high demand, e.g., for processing systems integrated with gas purifiers. The positive solution of this problem has become possible only now due to the appearance of reactive getters (reactants) that serve as highly efficient sinks for gas impurities and our sorption model of the processes, which take place in gas purifiers with these reactants. According to the given model the appearance of a single valued functional connection between the purity of the gas product and the duration of the treatment of the gas flow by the sorbing powder is typical for any system Me -Y, where Me is a powder reactant and Y is an impurity gas. This strict correlation provides the mathematical justification to a simple method of determining the concentration of the impurity in the gas flow at the exit from the gas purifier. This method comes down to measuring of the quantity of the purified gas by a gas flow meter, the readings of which are graduated in the units of gas concentration.展开更多
BACKGROUND Currently, it is difficult to predict the complications of children at the early stage of sepsis. Brighton pediatric early warning score(PEWS) is a disease risk assessment system that is simple and easy to ...BACKGROUND Currently, it is difficult to predict the complications of children at the early stage of sepsis. Brighton pediatric early warning score(PEWS) is a disease risk assessment system that is simple and easy to operate, which has good sensitivity and specificity in disease recognition among children. Because detection indicators vary widely in children, a single indicator is difficult to assess the posttreatment status of children with sepsis.AIM To investigate the relationship between serological markers, Brighton PEWS, and death in children with sepsis after treatment.METHODS A total of 205 children diagnosed with sepsis at our hospital were enrolled. The baseline data, serum scores, and PEWS scores were recorded. In the nested casecontrol study, children who died during the study period were included in an observation group. According to the matching principle, the children who were not dead in the same cohort were included in a control group. The influencing factors of death in children with sepsis after treatment and the value of each evaluation index in predicting the prognosis of children were analyzed.RESULTS A total of 96 children were enrolled in the study, including 48 each in the observation group and the control group. Multivariate logistic regression analysis indicated that antibacterial treatments within 1 h(P = 0.017), shock(P = 0.044),multiple organ dysfunction syndrome(MODS)(P = 0.027), serum procalcitonin(PCT)(P = 0.047), serum albumin(ALB)(P = 0.024), and PEWS(P = 0.012) were independent risk factors for the death of children with sepsis. The area under the curve of the combination of ALB, PCT, and PEWS to predict the death in children with sepsis was the highest(0.908).CONCLUSION Antibacterial treatments within 1 h, shock, MODS, PCT, ALB, and PEWS are independent risk factors for the death of children with sepsis. The predictive accuracy of the combination of PCT, ALB, and PEWS for the prognosis of children with sepsis is the best.展开更多
A novel flocking control approach is proposed for multi-agent systems by integrating the variables of velocities, motion directions, and positions of agents. A received signal strength indicator (RSSI) is applied as a...A novel flocking control approach is proposed for multi-agent systems by integrating the variables of velocities, motion directions, and positions of agents. A received signal strength indicator (RSSI) is applied as a variable to estimate the inter-distance between agents. A key parameter that contains the local information of agents is defined, and a multi-variable controller is proposed based on the parameter. For the position control of agents, the RSSI is introduced to substitute the distance as a control variable in the systems. The advantages of RSSI include that the relative distance between every two agents can be adjusted through the communication quality under different environments, and it can shun the shortage of the limit of sensors. Simulation studies demonstrate the effectiveness of the proposed control approach.展开更多
Since July 2010,the prices of geographical indication products have risen with the occurrence of inflation.In contrast with other products,geographical indication products are distinct.The increasing prices of geograp...Since July 2010,the prices of geographical indication products have risen with the occurrence of inflation.In contrast with other products,geographical indication products are distinct.The increasing prices of geographical indication goods have their own necessities.From the perspective of the products,they are equipped with appreciation potential due to the cultural pe culiarities.From the historical standpoint,their prices have not been high as well as other agricultural products.Realistically,the increase in their prices results from the costs of labors and raw materials.Therefore,the prices of geographical indication products rise to catch up.Not only are their prices at a reasonable level,but also they are beneficial to increase peasants'income.In con clusion,it is necessary that the strategies which are different from those of other products be adopted to regulate and control the prices of geographical indication products.展开更多
A synergistic pathway is regarded as a critical measure for tackling the intertwined challenges of climate change and air pollution in China. However, there is as yet no indicator that can comprehensively reflect such...A synergistic pathway is regarded as a critical measure for tackling the intertwined challenges of climate change and air pollution in China. However, there is as yet no indicator that can comprehensively reflect such synergistic effects;hence, existing studies lack a consistent framework for comparison. Here, we introduce a new synergistic indicator defined as the pollutant generation per gross domestic product (GDP) and adopt an integrated analysis framework by linking the logarithmic mean Divisia index (LMDI) method, response surface model (RSM), and global exposure mortality model (GEMM) to evaluate the synergistic effects of carbon mitigation on both air pollutant reduction and public health in China. The results show that synergistic effects played an increasingly important role in the emissions mitigation of SO_(2), NOx, and primary particulate matter with an aerodynamic diameter no greater than 2.5 μm (PM2.5), and the synergistic mitigation of pollutants respectively increase from 3.1, 1.4, and 0.3 Mt during the 11th Five-Year Plan (FYP) (2006–2010) to 5.6, 3.7, and 1.9 Mt during the 12th FYP (2011–2015). Against the non-control scenario, synergistic effects alone contributed to a 15% reduction in annual mean PM2.5 concentration, resulting in the prevention of 0.29 million (95% confidential interval: 0.28–0.30) PM2.5-attributable excess deaths in 2015. Synergistic benefits to air quality improvement and public health were remarkable in the developed and population-dense eastern provinces and municipalities. With the processes of urbanization and carbon neutrality in the future, synergistic effects are expected to continue to increase. Realizing climate targets in advance in developed regions would concurrently bring strong synergistic effects to air quality and public health.展开更多
Interacting The highest storage capacity of a circular tank makes it pop-ular in process industries.Because of the varying surface area of the cross-sec-tions of the tank,this two-tank level system has nonlinear chara...Interacting The highest storage capacity of a circular tank makes it pop-ular in process industries.Because of the varying surface area of the cross-sec-tions of the tank,this two-tank level system has nonlinear characteristics.Controlling theflow rate of liquid is one of the most difficult challenges in the production process.This proposed effort is critical in preventing time delays and errors by managing thefluid level.Several scholars have explored and explored ways to reduce the problem of nonlinearity,but their techniques have not yielded better results.Different types of controllers with various techniques are implemented by the proposed system.Sliding Mode Controller(SMC)with Fractional Order PID Controller based on Intelligent Adaptive Neuro-Fuzzy Infer-ence System(ANFIS)is a novel technique for liquid level regulation in an inter-connected spherical tank system to avoid interferences and achieve better performance in comparison of rise time,settling time,and overshoot decrease.Evaluating the simulated results acquired by the controller yields the efficiency of the proposed system.The simulated results were produced using MATLAB 2018 and the FOMCON toolbox.Finally,the performance of the conventional controller(FOPID,PID-SMC)and proposed ANFIS based SMC-FOPID control-lers are compared and analyzed the performance indices.展开更多
基金This study was supported by the National Administration of Traditional Chinese Medicine(SATCM-2015-BZ402).
文摘Objective:To assess outcome indicators in clinical trials and provide a reference for establishing a core outcome set to treat hyperplasia of mammary gland(HMG)with traditional Chinese medicine(TCM).Methods:Eight online databases were searched from their inception to December 31,2022,to assess outcomes reported in randomized controlled trials(RCTs)of HMG treated with TCM.The quality of the included studies was assessed according to the Cochrane Risk of Bias Assessment Tool.All outcomes were extracted,classified,and described.Results:A total of 8249 articles were initially retrieved.Of these,70 articles were eligible and involved 10618 participants with HMG.A total of 17 outcome indicators with a frequency of 271 times were involved and were collected according to six outcome domains.Conclusions:The core outcomes of RCTs of HMG treated with TCM are large and divergent.There are problems in evaluation standards,primary and secondary outcomes,TCM characteristic indicators,long-term prognosis,and standardization of reporting.It is recommended to strengthen the trial design and actively construct the core outcome sets with TCM characteristics for HMG.
基金National Key R&D Program of China Special Funding(2017YFC0805305)National Natural Science Foundation of China(41601574)Chinese Academy of Engineering Institute-Local Cooperation Project(2019-CQ-ZD-4)。
文摘The biggest environmental problem caused by the construction of tunnels adjacent to high-rise buildings is the settlement of buildings.The paper analyzes the influence of tunnel excavation on the deformation of the superstructure and the deformation mode of the superstructure.It introduces the indicators and standards for the construction control of tunnel adjacent to the building at home and abroad.Combined with the Yuzhong tunnel project under construction in Chongqing,the main monitoring indicators and control standards of the Yuzhong Tunnel passing through the main buildings are given after comprehensive analysis and considerations,which provide a reference for the deformation control indicators of similar urban traffic tunnels adjacent to high-rise buildings.
文摘The air conditioning system in the Umm Al-Qura University (Albdiya Campus) was conceived to be a district cooling by a remote chilled water plant. Recently, there are two chilled water plants in the university installed strategically to provide chilled water to all the academic and administrative buildings of the university through distribution network with total capacity approximately of 12,000 tons of refrigeration. The plants were built based on cooling towers with open water cycle as heat rejection system. Water treatment chemicals has been used to protect the cooling systems from corrosion, scaling and microbiological fouling accompanied with dissolved and suspended water impurities. Different methods are being used to determine and control the treatment chemical concentrations and system performance indicators. Traditional chemical controller has drawback of indirect measurements and set points. The purpose of this paper is to present a solution to overcome the problems of traditional and conventional chemical treatment and control sys-tems. Central cooling plant number (1) assigned to perform experimental setup using new chemical treatment technology. Advanced automatic chemical treatment controller installed on condensers (1, 2 and 3), and certain key performance indicators were selected and monitored such as chemical and water consumption, power, energy saving, and maintaining system integrity and efficiency. Satisfactory results were obtained in terms of performance and cost of operation.
文摘One of the main problems in the flow-through gas purification technologies is related with continuous control of the outlet gas purity. The information concerning purity of the produced gas is on high demand, e.g., for processing systems integrated with gas purifiers. The positive solution of this problem has become possible only now due to the appearance of reactive getters (reactants) that serve as highly efficient sinks for gas impurities and our sorption model of the processes, which take place in gas purifiers with these reactants. According to the given model the appearance of a single valued functional connection between the purity of the gas product and the duration of the treatment of the gas flow by the sorbing powder is typical for any system Me -Y, where Me is a powder reactant and Y is an impurity gas. This strict correlation provides the mathematical justification to a simple method of determining the concentration of the impurity in the gas flow at the exit from the gas purifier. This method comes down to measuring of the quantity of the purified gas by a gas flow meter, the readings of which are graduated in the units of gas concentration.
文摘BACKGROUND Currently, it is difficult to predict the complications of children at the early stage of sepsis. Brighton pediatric early warning score(PEWS) is a disease risk assessment system that is simple and easy to operate, which has good sensitivity and specificity in disease recognition among children. Because detection indicators vary widely in children, a single indicator is difficult to assess the posttreatment status of children with sepsis.AIM To investigate the relationship between serological markers, Brighton PEWS, and death in children with sepsis after treatment.METHODS A total of 205 children diagnosed with sepsis at our hospital were enrolled. The baseline data, serum scores, and PEWS scores were recorded. In the nested casecontrol study, children who died during the study period were included in an observation group. According to the matching principle, the children who were not dead in the same cohort were included in a control group. The influencing factors of death in children with sepsis after treatment and the value of each evaluation index in predicting the prognosis of children were analyzed.RESULTS A total of 96 children were enrolled in the study, including 48 each in the observation group and the control group. Multivariate logistic regression analysis indicated that antibacterial treatments within 1 h(P = 0.017), shock(P = 0.044),multiple organ dysfunction syndrome(MODS)(P = 0.027), serum procalcitonin(PCT)(P = 0.047), serum albumin(ALB)(P = 0.024), and PEWS(P = 0.012) were independent risk factors for the death of children with sepsis. The area under the curve of the combination of ALB, PCT, and PEWS to predict the death in children with sepsis was the highest(0.908).CONCLUSION Antibacterial treatments within 1 h, shock, MODS, PCT, ALB, and PEWS are independent risk factors for the death of children with sepsis. The predictive accuracy of the combination of PCT, ALB, and PEWS for the prognosis of children with sepsis is the best.
基金supported by the National Basic Research Program of China (973Program) under Grant No. 2010CB731800the National Natural Science Foundation of China under Grant No. 60934003 and 61074065the Key Project for Natural Science Research of Hebei Education Departmentunder Grant No. ZD200908
文摘A novel flocking control approach is proposed for multi-agent systems by integrating the variables of velocities, motion directions, and positions of agents. A received signal strength indicator (RSSI) is applied as a variable to estimate the inter-distance between agents. A key parameter that contains the local information of agents is defined, and a multi-variable controller is proposed based on the parameter. For the position control of agents, the RSSI is introduced to substitute the distance as a control variable in the systems. The advantages of RSSI include that the relative distance between every two agents can be adjusted through the communication quality under different environments, and it can shun the shortage of the limit of sensors. Simulation studies demonstrate the effectiveness of the proposed control approach.
文摘Since July 2010,the prices of geographical indication products have risen with the occurrence of inflation.In contrast with other products,geographical indication products are distinct.The increasing prices of geographical indication goods have their own necessities.From the perspective of the products,they are equipped with appreciation potential due to the cultural pe culiarities.From the historical standpoint,their prices have not been high as well as other agricultural products.Realistically,the increase in their prices results from the costs of labors and raw materials.Therefore,the prices of geographical indication products rise to catch up.Not only are their prices at a reasonable level,but also they are beneficial to increase peasants'income.In con clusion,it is necessary that the strategies which are different from those of other products be adopted to regulate and control the prices of geographical indication products.
基金supported by the National Natural Science Foundation of China(72025401,71974108,and 72140003)the Tsinghua University-INDITEX Sustainable Development Fund.
文摘A synergistic pathway is regarded as a critical measure for tackling the intertwined challenges of climate change and air pollution in China. However, there is as yet no indicator that can comprehensively reflect such synergistic effects;hence, existing studies lack a consistent framework for comparison. Here, we introduce a new synergistic indicator defined as the pollutant generation per gross domestic product (GDP) and adopt an integrated analysis framework by linking the logarithmic mean Divisia index (LMDI) method, response surface model (RSM), and global exposure mortality model (GEMM) to evaluate the synergistic effects of carbon mitigation on both air pollutant reduction and public health in China. The results show that synergistic effects played an increasingly important role in the emissions mitigation of SO_(2), NOx, and primary particulate matter with an aerodynamic diameter no greater than 2.5 μm (PM2.5), and the synergistic mitigation of pollutants respectively increase from 3.1, 1.4, and 0.3 Mt during the 11th Five-Year Plan (FYP) (2006–2010) to 5.6, 3.7, and 1.9 Mt during the 12th FYP (2011–2015). Against the non-control scenario, synergistic effects alone contributed to a 15% reduction in annual mean PM2.5 concentration, resulting in the prevention of 0.29 million (95% confidential interval: 0.28–0.30) PM2.5-attributable excess deaths in 2015. Synergistic benefits to air quality improvement and public health were remarkable in the developed and population-dense eastern provinces and municipalities. With the processes of urbanization and carbon neutrality in the future, synergistic effects are expected to continue to increase. Realizing climate targets in advance in developed regions would concurrently bring strong synergistic effects to air quality and public health.
文摘Interacting The highest storage capacity of a circular tank makes it pop-ular in process industries.Because of the varying surface area of the cross-sec-tions of the tank,this two-tank level system has nonlinear characteristics.Controlling theflow rate of liquid is one of the most difficult challenges in the production process.This proposed effort is critical in preventing time delays and errors by managing thefluid level.Several scholars have explored and explored ways to reduce the problem of nonlinearity,but their techniques have not yielded better results.Different types of controllers with various techniques are implemented by the proposed system.Sliding Mode Controller(SMC)with Fractional Order PID Controller based on Intelligent Adaptive Neuro-Fuzzy Infer-ence System(ANFIS)is a novel technique for liquid level regulation in an inter-connected spherical tank system to avoid interferences and achieve better performance in comparison of rise time,settling time,and overshoot decrease.Evaluating the simulated results acquired by the controller yields the efficiency of the proposed system.The simulated results were produced using MATLAB 2018 and the FOMCON toolbox.Finally,the performance of the conventional controller(FOPID,PID-SMC)and proposed ANFIS based SMC-FOPID control-lers are compared and analyzed the performance indices.
