Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate...Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate the skin dose calculation accuracy of the XIO 4.04 treatment planning system. Methods: More investigations for the influences of IMRT on skin doses would increase its applications for many treatment sites. Measuring skin doses in real treatment situations would reduce the uncertainty of skin dose prediction. In this work a pediatric human phantom was covered by a layer of 1 mm bolus at three treatment sites and thermoluminescent dosimeter (TLD) chips were inserted into the bolus at each treatment site before CT scan. Two different treatment plans [three-dimensional conformal radiation therapy (3DCRT) and IMRT] for each treatment sites were performed on XIO 4.04 treatment planning system using superposition algorism. Results: The results showed that the surface doses for 3DCRT were higher than the surface doses in IMRT by 1.6%, 2.5% and 3.2% for brain, abdomen and pelvis sites respectively. There was good agreement between measured and calculated surface doses, where the calculated surface dose was 15.5% for brain tumor calculated with 3DCRT whereas the measured surface dose was 12.1%. For abdomen site the calculated surface dose for IMRT treatment plan was 16.5% whereas the measured surface dose was 12.6%. Conclusion: The skin dose in IMRT for deep seated tumors is lower than that in 3DCRT which is another advantage for the IMRT. The TLD readings showed that the difference between the calculated and measured point dose is negligible. The superposition calculation algorism of the XIO 4.04 treatment planning system modeled the superficial dose well.展开更多
This paper presents the preclinical evaluation of a novel immobilization system for patients undergoing external beam radiation treatment of head and neck tumors. An immobilization mask is manufactured directly from a...This paper presents the preclinical evaluation of a novel immobilization system for patients undergoing external beam radiation treatment of head and neck tumors. An immobilization mask is manufactured directly from a 3-D model, built using the CT data routinely acquired for treatment planning so there is no need to take plaster of Paris moulds. Research suggests that many patients find the mould room visit distressing and so rapid prototyping could potentially improve the overall patient experience. Evaluation of a computer model of the immobilization system using an anthropomorphic phantom shows that >99% of vertices are within a tolerance of ±0.2 mm. Hausdorff distance was used to analyze CT slices obtained by rescanning the phantom with a printed mask in position. These results show that for >80% of the slices the median “worse-case” tolerance is approximately 4 mm. These measurements suggest that printed masks can achieve similar levels of immobilization to those of systems currently in clinical use.展开更多
Small radiation fields are abundantly used in modern radiotherapy techniques like in IMRT and SRS. In order to commission these techniques, dosimetric data for small fields is required. The purpose of this study is to...Small radiation fields are abundantly used in modern radiotherapy techniques like in IMRT and SRS. In order to commission these techniques, dosimetric data for small fields is required. The purpose of this study is to compare dosimetric measurements with two different ion chambers cc13, and cc01 for smaller fields. Dosimetric measurements are beam profile, output factor, pdds, and collimator factor. Dosimetric data is acquired in water phantom for two different photon beam energies 6 MV and 15 MV with zero gantry angle. In beam profiles cc13 chamber, measure wider penumbra as compare to cc01. And this wider measurement of penumbra occurs for smaller as well as for larger field sizes. Accumulated relative error in the measurement of penumbra for number of field sizes and 6 MV at dmax, and at 10 cm depth are 34.32% and 27.72% respectively. Accumulated relative error in the measurement of penumbra for number of field sizes and 15 MV at dmax, and at 10 cm depth are 28.49% and 23.92%. In case of output factor for smaller fields cc13 underestimates the output factor relative to cc01, with non-linear increase for smaller fields. But for larger fields, this increase in output factor is almost linear difference of two chambers is decreased. For very smaller fields × 2 cm, relative error in output factor of cc13 and cc01 is greater than 5% and rapidly increases with decreasing field size. But for lager fields, this relative error is negligible. In measurement of pdds after the buildup region difference occurs in the response of two chambers cc13 and cc01 for smaller fields. For field sizes ≤2 cm × 2 cm average cc13-cc01 at various depths 30 cm, 40 cm, 50 cm, 60 cm, 70 cm, and 80 cm is almost greater than 0.5 cm. And similarly as output factor, this difference (cc13-cc01) increases with field size decreasing.展开更多
文摘Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate the skin dose calculation accuracy of the XIO 4.04 treatment planning system. Methods: More investigations for the influences of IMRT on skin doses would increase its applications for many treatment sites. Measuring skin doses in real treatment situations would reduce the uncertainty of skin dose prediction. In this work a pediatric human phantom was covered by a layer of 1 mm bolus at three treatment sites and thermoluminescent dosimeter (TLD) chips were inserted into the bolus at each treatment site before CT scan. Two different treatment plans [three-dimensional conformal radiation therapy (3DCRT) and IMRT] for each treatment sites were performed on XIO 4.04 treatment planning system using superposition algorism. Results: The results showed that the surface doses for 3DCRT were higher than the surface doses in IMRT by 1.6%, 2.5% and 3.2% for brain, abdomen and pelvis sites respectively. There was good agreement between measured and calculated surface doses, where the calculated surface dose was 15.5% for brain tumor calculated with 3DCRT whereas the measured surface dose was 12.1%. For abdomen site the calculated surface dose for IMRT treatment plan was 16.5% whereas the measured surface dose was 12.6%. Conclusion: The skin dose in IMRT for deep seated tumors is lower than that in 3DCRT which is another advantage for the IMRT. The TLD readings showed that the difference between the calculated and measured point dose is negligible. The superposition calculation algorism of the XIO 4.04 treatment planning system modeled the superficial dose well.
文摘This paper presents the preclinical evaluation of a novel immobilization system for patients undergoing external beam radiation treatment of head and neck tumors. An immobilization mask is manufactured directly from a 3-D model, built using the CT data routinely acquired for treatment planning so there is no need to take plaster of Paris moulds. Research suggests that many patients find the mould room visit distressing and so rapid prototyping could potentially improve the overall patient experience. Evaluation of a computer model of the immobilization system using an anthropomorphic phantom shows that >99% of vertices are within a tolerance of ±0.2 mm. Hausdorff distance was used to analyze CT slices obtained by rescanning the phantom with a printed mask in position. These results show that for >80% of the slices the median “worse-case” tolerance is approximately 4 mm. These measurements suggest that printed masks can achieve similar levels of immobilization to those of systems currently in clinical use.
文摘Small radiation fields are abundantly used in modern radiotherapy techniques like in IMRT and SRS. In order to commission these techniques, dosimetric data for small fields is required. The purpose of this study is to compare dosimetric measurements with two different ion chambers cc13, and cc01 for smaller fields. Dosimetric measurements are beam profile, output factor, pdds, and collimator factor. Dosimetric data is acquired in water phantom for two different photon beam energies 6 MV and 15 MV with zero gantry angle. In beam profiles cc13 chamber, measure wider penumbra as compare to cc01. And this wider measurement of penumbra occurs for smaller as well as for larger field sizes. Accumulated relative error in the measurement of penumbra for number of field sizes and 6 MV at dmax, and at 10 cm depth are 34.32% and 27.72% respectively. Accumulated relative error in the measurement of penumbra for number of field sizes and 15 MV at dmax, and at 10 cm depth are 28.49% and 23.92%. In case of output factor for smaller fields cc13 underestimates the output factor relative to cc01, with non-linear increase for smaller fields. But for larger fields, this increase in output factor is almost linear difference of two chambers is decreased. For very smaller fields × 2 cm, relative error in output factor of cc13 and cc01 is greater than 5% and rapidly increases with decreasing field size. But for lager fields, this relative error is negligible. In measurement of pdds after the buildup region difference occurs in the response of two chambers cc13 and cc01 for smaller fields. For field sizes ≤2 cm × 2 cm average cc13-cc01 at various depths 30 cm, 40 cm, 50 cm, 60 cm, 70 cm, and 80 cm is almost greater than 0.5 cm. And similarly as output factor, this difference (cc13-cc01) increases with field size decreasing.
