BACKGROUND A new nomenclature consensus has emerged for liver diseases that were previously known as non-alcoholic fatty liver disease(NAFLD)and metabolic dysfunction-associated fatty liver disease(MAFLD).They are now...BACKGROUND A new nomenclature consensus has emerged for liver diseases that were previously known as non-alcoholic fatty liver disease(NAFLD)and metabolic dysfunction-associated fatty liver disease(MAFLD).They are now defined as metabolic dysfunction-associated steatotic liver disease(MASLD),which includes cardiometabolic criteria in adults.This condition,extensively studied in obese or overweight patients,constitutes around 30%of the population,with a steady increase worldwide.Lean patients account for approximately 10%-15%of the MASLD population.However,the pathogenesis is complex and is not well understood.AIM To systematically review the literature on the diagnosis,pathogenesis,characteristics,and prognosis in lean MASLD patients and provide an interpretation of these new criteria.METHODS We conducted a comprehensive database search on PubMed and Google Scholar between January 2012 and September 2023,specifically focusing on lean NAFLD,MAFLD,or MASLD patients.We include original articles with patients aged 18 years or older,with a lean body mass index categorized according to the World Health Organization criteria,using a cutoff of 25 kg/m2 for the general population and 23 kg/m2 for the Asian population.RESULTS We include 85 studies in our analysis.Our findings revealed that,for lean NAFLD patients,the prevalence rate varied widely,ranging from 3.8%to 34.1%.The precise pathogenesis mechanism remained elusive,with associations found in genetic variants,epigenetic modifications,and adaptative metabolic response.Common risk factors included metabolic syndrome,hypertension,and type 2 diabetes mellitus,but their prevalence varied based on the comparison group involving lean patients.Regarding non-invasive tools,Fibrosis-4 index outperformed the NAFLD fibrosis score in lean patients.Lifestyle modifications aided in reducing hepatic steatosis and improving cardiometabolic profiles,with some medications showing efficacy to a lesser extent.However,lean NAFLD patients exhibited a worse prognosis compared to the obese or overweight counterpart.CONCLUSION MASLD is a complex disease comprising epigenetic,genetic,and metabolic factors in its pathogenesis.Results vary across populations,gender,and age.Limited data exists on clinical practice guidelines for lean patients.Future studies employing this new nomenclature can contribute to standardizing and generalizing results among lean patients with steatotic liver disease.展开更多
Batteries that utilize low-cost elemental sulfur and light metallic lithium as electrodes have great potential in achieving high energy density.However,building a lithium-sulfur(Li-S)full battery by controlling the el...Batteries that utilize low-cost elemental sulfur and light metallic lithium as electrodes have great potential in achieving high energy density.However,building a lithium-sulfur(Li-S)full battery by controlling the electrolyte volume generally produces low practical energy because of the limited electrochemical Li-S redox.Herein,the high energy/high performance of a Li-S full battery with practical sulfur loading and minimum electrolyte volume is reported.A unique hybrid architecture configured with Ni-Co metal alloy(NiCo)and metal oxide(NiCoO_(2))nanoparticles heterogeneously anchored in carbon nanotube-embedded selfstanding carbon matrix is fabricated as a host for sulfur.This work demonstrates the considerable improvement that the hybrid structure's high conductivity and satisfactory porosity promote the transport of electrons and lithium ions in Li-S batteries.Through experimental and theoretical validations,the function of NiCo and NiCoO_(2) nanoparticles as an efficient polysulfide mediator is established.These particles afford polysulfide anchoring and catalytic sites for Li-S redox reaction,thus improving the redox conversion reversibility.Even at high sulfur loading,the nanostructured Ni-Co metal alloy and metal oxide enable to have stable cycling performance under lean electrolyte conditions both in half-cell and full-cell batteries using a graphite anode.展开更多
The use of lithium-sulfur batteries under high sulfur loading and low electrolyte concentrations is severely restricted by the detrimental shuttling behavior of polysulfides and the sluggish kinetics in redox processe...The use of lithium-sulfur batteries under high sulfur loading and low electrolyte concentrations is severely restricted by the detrimental shuttling behavior of polysulfides and the sluggish kinetics in redox processes.Two-dimensional(2D)few layered black phosphorus with fully exposed atoms and high sulfur affinity can be potential lithium-sulfur battery electrocatalysts,which,however,have limitations of restricted catalytic activity and poor electrochemical/chemical stability.To resolve these issues,we developed a multifunctional metal-free catalyst by covalently bonding few layered black phosphorus nanosheets with nitrogen-doped carbon-coated multiwalled carbon nanotubes(denoted c-FBP-NC).The experimental characterizations and theoretical calculations show that the formed polarized P-N covalent bonds in c-FBP-NC can efficiently regulate electron transfer from NC to FBP and significantly promote the capture and catalysis of lithium polysulfides,thus alleviating the shuttle effect.Meanwhile,the robust 1D-2D interwoven structure with large surface area and high porosity allows strong physical confinement and fast mass transfer.Impressively,with c-FBP-NC as the sulfur host,the battery shows a high areal capacity of 7.69 mAh cm^(−2) under high sulfur loading of 8.74 mg cm^(−2) and a low electrolyte/sulfur ratio of 5.7μL mg^(−1).Moreover,the assembled pouch cell with sulfur loading of 4 mg cm^(−2) and an electrolyte/sulfur ratio of 3.5μL mg^(−1) shows good rate capability and outstanding cyclability.This work proposes an interfacial and electronic structure engineering strategy for fast and durable sulfur electrochemistry,demonstrating great potential in lithium-sulfur batteries.展开更多
The effects of nano-CaO contents on the microstructure,mechanical properties and corrosion resistance of lean Mg-1Zn alloy were investigated.The results showed that the addition of nano-CaO significantly refined the g...The effects of nano-CaO contents on the microstructure,mechanical properties and corrosion resistance of lean Mg-1Zn alloy were investigated.The results showed that the addition of nano-CaO significantly refined the grain size and improved mechanical properties of the Mg-1Zn alloy.At the same time,CaO reacted with molten Mg in situ to form nano-MgO,whose corrosion product in SBF solution was the same with the degradation product of Mg matrix,resulting in the enhanced compactness of the Mg(OH)_(2) layer and reduced corrosion rate of matrix.The Mg-1Zn alloy had lower corrosion resistance due to excessively large grain size and shedding of corrosion products.The composite with 0.5 wt.%CaO had the best corrosion resistance with a weight loss of 9.875 mg·y^(-1)·mm^(-2)due to the small number of Ca_(2)Mg_(6)Zn_(3) phase and suitable grain size.While for composites with high content of CaO(0.7 wt.%and 1.0 wt.%),they had lower corrosion resistance due to the coexistence of large number of Ca_(2)Mg_(6)Zn_(3) and Mg_(2)Ca at grain boundaries,especially for 1.0 wt.%CaO composite,resulting from the strong micro-galvanic corrosion.展开更多
In contemporary contexts,Lean Six Sigma(LSS)is extensively utilized and has evolved across various sectors due to its substantial benefits.This paper aims to explore the definition,origin,and development of LSS,as wel...In contemporary contexts,Lean Six Sigma(LSS)is extensively utilized and has evolved across various sectors due to its substantial benefits.This paper aims to explore the definition,origin,and development of LSS,as well as its key tools,methods,theoretical research,and future prospects.Furthermore,it analyzes the theoretical foundations and practical applications of LSS in-depth,with an emphasis on anticipating future development trends.The goal is to provide readers with a comprehensive overview of LSS and offer insights for enterprises seeking to implement LSS for process improvement and innovation.展开更多
Improvement on extinction and pollution emission have become one of the most prominent research topics in gas turbine.It is widely recognized that the fuel/air mixture distribution in the recirculation zone is a criti...Improvement on extinction and pollution emission have become one of the most prominent research topics in gas turbine.It is widely recognized that the fuel/air mixture distribution in the recirculation zone is a critical factor in improving lean blow-out(LBO) and ignition.This paper proposed a new low emission scheme with fuel staged centrally and hybrid injector to improve flameout and emission.A relative small amount of fuel enters into central pilot airblast atomizer burner and then atomized by inner swirl air.The remaining majority of fuel is directly injected into vane channels of the primary swirler through a series of holes located on the sidewall of the main stage.Only pilot stage is fueled under ignition and lean flameout condition.The uniformity of fuel/air mixture distribution in the primary zone of the new design decreases NOX emission,meanwhile the fuel air mixture in pilot recirculation zone is locally rich to improve flameout and ignition.Experimental investigation was conducted to compare the new scheme with baseline design of dual-swirler in terms of LBO and ignition characteristics under the same condition in a multi-sector combustor.It is found that the fuel-air ratio of ignition limit and LBO decrease with the reference velocity increasing.The experimental results also show that the new scheme successfully improve lean blow-out and broaden the operation range of the combustor.The experimental results indicated that the centrally staged scheme can widen the operation boundary of the combustor and can provide guidance for design and optimization of combustion chamber.展开更多
Lithium–sulfur(Li–S) batteries have received widespread attention, and lean electrolyte Li–S batteries have attracted additional interest because of their higher energy densities. This review systematically analyze...Lithium–sulfur(Li–S) batteries have received widespread attention, and lean electrolyte Li–S batteries have attracted additional interest because of their higher energy densities. This review systematically analyzes the effect of the electrolyte-to-sulfur(E/S) ratios on battery energy density and the challenges for sulfur reduction reactions(SRR) under lean electrolyte conditions. Accordingly, we review the use of various polar transition metal sulfur hosts as corresponding solutions to facilitate SRR kinetics at low E/S ratios(< 10 μL mg~(-1)), and the strengths and limitations of different transition metal compounds are presented and discussed from a fundamental perspective. Subsequently, three promising strategies for sulfur hosts that act as anchors and catalysts are proposed to boost lean electrolyte Li–S battery performance. Finally, an outlook is provided to guide future research on high energy density Li–S batteries.展开更多
This paper presents a study on the design strategy of leaning-type arch bridges.The main characteristics of leaning-type arch bridges are first introduced;Kunshan Yufeng Bridge is taken as an example to discuss differ...This paper presents a study on the design strategy of leaning-type arch bridges.The main characteristics of leaning-type arch bridges are first introduced;Kunshan Yufeng Bridge is taken as an example to discuss different aspects of a design strategy,which includes self-system optimization,selection of beam length and bridge deck position,and other aspects.This paper can be used as a reference to further improve and develop bridge design.展开更多
目的利用精益六西格玛(lean six sigma,LSS)管理中的界定、测量、分析、改进和控制(define,measure,analyze,improve,control;DMAIC)模型,优化妊娠合并脑血管病患者就医流程,提高患者就医效率,保障母婴安全。方法2021年12月,首都医科大...目的利用精益六西格玛(lean six sigma,LSS)管理中的界定、测量、分析、改进和控制(define,measure,analyze,improve,control;DMAIC)模型,优化妊娠合并脑血管病患者就医流程,提高患者就医效率,保障母婴安全。方法2021年12月,首都医科大学附属北京天坛医院根据DMAIC模型,对危重孕产妇的就诊流程进行优化:梳理就诊流程,明确到院—医嘱开立、采血—送检、医嘱开立—影像学检查为院内延误的关键环节,对上述环节进行流程跟踪及分析,找出延误原因,并采取改进措施,优化流程。本研究回顾性纳入流程优化前(2019年1月—2021年12月)的妊娠合并脑血管病患者为优化前组,流程优化后(2022年1月—2023年12月)的患者为优化后组。比较两组患者就诊流程中的到院—医嘱开立、采血—送检、医嘱开立—影像学检查、到院—办理住院的时间。结果急诊就诊流程优化后,妊娠合并脑血管病患者的总体就诊效率提高。到院—医嘱开立[24.0(13.5~38.5)min vs.39.0(17.5~98.0)min,P=0.027]、医嘱开立—影像学检查[48.0(10.0~73.0)min vs.65.5(22.7~90.7)min,P=0.025]以及到院—办理入院总时间[120.0(93.0~149.0)min vs.218.0(123.0~382.7)mi n,P<0.001]均较优化前缩短,差异有统计学意义;采血—送检时间有缩短趋势,但优化前后差异无统计学意义。结论使用DMAIC模型能够明确流程优化的关键环节,优化妊娠合并脑血管病患者的急诊就诊流程。展开更多
目的研究集中管理模式下精益六西格玛(lean six sigma,LSS)管理法在优化生命支持类医疗设备维修管理流程方面的应用价值。方法以输液泵和注射泵为例,运用LSS管理方法中的界定、测量、分析、改进和控制5个阶段流程对生命支持类医疗设备...目的研究集中管理模式下精益六西格玛(lean six sigma,LSS)管理法在优化生命支持类医疗设备维修管理流程方面的应用价值。方法以输液泵和注射泵为例,运用LSS管理方法中的界定、测量、分析、改进和控制5个阶段流程对生命支持类医疗设备维修管理难点进行分析,采用组织系统模型流程管理及鱼骨图等方法,分析影响设备维修管理的关键环节,提出在集中管理模式中简化维修审批流程、建立集中管理设备维修和质量控制运行机制、规范设备消毒和检测制度等改进方案,对LSS管理方法实施前后输液泵和注射泵实际维修周期和维修费用进行比较。结果LSS管理方法实施后,输液泵和注射泵设备实际维修时长分别缩短至(6.75±1.81)d和(5.89±1.25)d,维修周期分别缩短26.87%和20.19%,差异有统计学意义(P<0.05);输液泵和注射泵每月单次维修费用分别降低至232.10[32.50,291.00]元和164.40[32.80,183.40]元,差异有统计学意义(P<0.05);月均维修费用分别降低至1217.00元和1426.75元,分别降低了16.54%和28.20%,达到了LSS管理方法的工作目标。结论本研究提出的LSS管理方法可以有效分析医疗设备维修管理中的难点,从而在集中管理模式下针对性优化管理流程,可有效提升设备维修效率,降低维修成本。展开更多
文摘BACKGROUND A new nomenclature consensus has emerged for liver diseases that were previously known as non-alcoholic fatty liver disease(NAFLD)and metabolic dysfunction-associated fatty liver disease(MAFLD).They are now defined as metabolic dysfunction-associated steatotic liver disease(MASLD),which includes cardiometabolic criteria in adults.This condition,extensively studied in obese or overweight patients,constitutes around 30%of the population,with a steady increase worldwide.Lean patients account for approximately 10%-15%of the MASLD population.However,the pathogenesis is complex and is not well understood.AIM To systematically review the literature on the diagnosis,pathogenesis,characteristics,and prognosis in lean MASLD patients and provide an interpretation of these new criteria.METHODS We conducted a comprehensive database search on PubMed and Google Scholar between January 2012 and September 2023,specifically focusing on lean NAFLD,MAFLD,or MASLD patients.We include original articles with patients aged 18 years or older,with a lean body mass index categorized according to the World Health Organization criteria,using a cutoff of 25 kg/m2 for the general population and 23 kg/m2 for the Asian population.RESULTS We include 85 studies in our analysis.Our findings revealed that,for lean NAFLD patients,the prevalence rate varied widely,ranging from 3.8%to 34.1%.The precise pathogenesis mechanism remained elusive,with associations found in genetic variants,epigenetic modifications,and adaptative metabolic response.Common risk factors included metabolic syndrome,hypertension,and type 2 diabetes mellitus,but their prevalence varied based on the comparison group involving lean patients.Regarding non-invasive tools,Fibrosis-4 index outperformed the NAFLD fibrosis score in lean patients.Lifestyle modifications aided in reducing hepatic steatosis and improving cardiometabolic profiles,with some medications showing efficacy to a lesser extent.However,lean NAFLD patients exhibited a worse prognosis compared to the obese or overweight counterpart.CONCLUSION MASLD is a complex disease comprising epigenetic,genetic,and metabolic factors in its pathogenesis.Results vary across populations,gender,and age.Limited data exists on clinical practice guidelines for lean patients.Future studies employing this new nomenclature can contribute to standardizing and generalizing results among lean patients with steatotic liver disease.
基金supported by the National Research Foundation of Korea (NRF)grant funded by the Korean government (MSIT) (NRF-2022R1C1C1011058)supported by the Korea Institute for Advancement of Technology (KIAT)grant funded by the Korean Government (MOTIE) (P0012748,HRD Program for Industrial Innovation).
文摘Batteries that utilize low-cost elemental sulfur and light metallic lithium as electrodes have great potential in achieving high energy density.However,building a lithium-sulfur(Li-S)full battery by controlling the electrolyte volume generally produces low practical energy because of the limited electrochemical Li-S redox.Herein,the high energy/high performance of a Li-S full battery with practical sulfur loading and minimum electrolyte volume is reported.A unique hybrid architecture configured with Ni-Co metal alloy(NiCo)and metal oxide(NiCoO_(2))nanoparticles heterogeneously anchored in carbon nanotube-embedded selfstanding carbon matrix is fabricated as a host for sulfur.This work demonstrates the considerable improvement that the hybrid structure's high conductivity and satisfactory porosity promote the transport of electrons and lithium ions in Li-S batteries.Through experimental and theoretical validations,the function of NiCo and NiCoO_(2) nanoparticles as an efficient polysulfide mediator is established.These particles afford polysulfide anchoring and catalytic sites for Li-S redox reaction,thus improving the redox conversion reversibility.Even at high sulfur loading,the nanostructured Ni-Co metal alloy and metal oxide enable to have stable cycling performance under lean electrolyte conditions both in half-cell and full-cell batteries using a graphite anode.
基金Jiangsu Provincial Department of Science and Technology,Grant/Award Number:BK20201190Fundamental Research Funds for“Young Talent Support Plan”of Xi'an Jiaotong University,Grant/Award Number:HG6J003+1 种基金“1000-Plan program”of Shaanxi Province and the Velux Foundations through the research center V-Sustain,Grant/Award Number:9455National Key R&D Program of China,。
文摘The use of lithium-sulfur batteries under high sulfur loading and low electrolyte concentrations is severely restricted by the detrimental shuttling behavior of polysulfides and the sluggish kinetics in redox processes.Two-dimensional(2D)few layered black phosphorus with fully exposed atoms and high sulfur affinity can be potential lithium-sulfur battery electrocatalysts,which,however,have limitations of restricted catalytic activity and poor electrochemical/chemical stability.To resolve these issues,we developed a multifunctional metal-free catalyst by covalently bonding few layered black phosphorus nanosheets with nitrogen-doped carbon-coated multiwalled carbon nanotubes(denoted c-FBP-NC).The experimental characterizations and theoretical calculations show that the formed polarized P-N covalent bonds in c-FBP-NC can efficiently regulate electron transfer from NC to FBP and significantly promote the capture and catalysis of lithium polysulfides,thus alleviating the shuttle effect.Meanwhile,the robust 1D-2D interwoven structure with large surface area and high porosity allows strong physical confinement and fast mass transfer.Impressively,with c-FBP-NC as the sulfur host,the battery shows a high areal capacity of 7.69 mAh cm^(−2) under high sulfur loading of 8.74 mg cm^(−2) and a low electrolyte/sulfur ratio of 5.7μL mg^(−1).Moreover,the assembled pouch cell with sulfur loading of 4 mg cm^(−2) and an electrolyte/sulfur ratio of 3.5μL mg^(−1) shows good rate capability and outstanding cyclability.This work proposes an interfacial and electronic structure engineering strategy for fast and durable sulfur electrochemistry,demonstrating great potential in lithium-sulfur batteries.
基金the financial support for this work from the National Natural Science Foundation of China(Nos.52171241,52201301 and 51871166)。
文摘The effects of nano-CaO contents on the microstructure,mechanical properties and corrosion resistance of lean Mg-1Zn alloy were investigated.The results showed that the addition of nano-CaO significantly refined the grain size and improved mechanical properties of the Mg-1Zn alloy.At the same time,CaO reacted with molten Mg in situ to form nano-MgO,whose corrosion product in SBF solution was the same with the degradation product of Mg matrix,resulting in the enhanced compactness of the Mg(OH)_(2) layer and reduced corrosion rate of matrix.The Mg-1Zn alloy had lower corrosion resistance due to excessively large grain size and shedding of corrosion products.The composite with 0.5 wt.%CaO had the best corrosion resistance with a weight loss of 9.875 mg·y^(-1)·mm^(-2)due to the small number of Ca_(2)Mg_(6)Zn_(3) phase and suitable grain size.While for composites with high content of CaO(0.7 wt.%and 1.0 wt.%),they had lower corrosion resistance due to the coexistence of large number of Ca_(2)Mg_(6)Zn_(3) and Mg_(2)Ca at grain boundaries,especially for 1.0 wt.%CaO composite,resulting from the strong micro-galvanic corrosion.
文摘In contemporary contexts,Lean Six Sigma(LSS)is extensively utilized and has evolved across various sectors due to its substantial benefits.This paper aims to explore the definition,origin,and development of LSS,as well as its key tools,methods,theoretical research,and future prospects.Furthermore,it analyzes the theoretical foundations and practical applications of LSS in-depth,with an emphasis on anticipating future development trends.The goal is to provide readers with a comprehensive overview of LSS and offer insights for enterprises seeking to implement LSS for process improvement and innovation.
基金supported by National Natural Science Foundation of China with project No.51306182
文摘Improvement on extinction and pollution emission have become one of the most prominent research topics in gas turbine.It is widely recognized that the fuel/air mixture distribution in the recirculation zone is a critical factor in improving lean blow-out(LBO) and ignition.This paper proposed a new low emission scheme with fuel staged centrally and hybrid injector to improve flameout and emission.A relative small amount of fuel enters into central pilot airblast atomizer burner and then atomized by inner swirl air.The remaining majority of fuel is directly injected into vane channels of the primary swirler through a series of holes located on the sidewall of the main stage.Only pilot stage is fueled under ignition and lean flameout condition.The uniformity of fuel/air mixture distribution in the primary zone of the new design decreases NOX emission,meanwhile the fuel air mixture in pilot recirculation zone is locally rich to improve flameout and ignition.Experimental investigation was conducted to compare the new scheme with baseline design of dual-swirler in terms of LBO and ignition characteristics under the same condition in a multi-sector combustor.It is found that the fuel-air ratio of ignition limit and LBO decrease with the reference velocity increasing.The experimental results also show that the new scheme successfully improve lean blow-out and broaden the operation range of the combustor.The experimental results indicated that the centrally staged scheme can widen the operation boundary of the combustor and can provide guidance for design and optimization of combustion chamber.
基金the Research Foundation-Flanders (FWO) for a Research Project (G0B3218N)the financial support by the National Natural Science Foundation of China (22005054)+3 种基金Natural Science Foundation of Fujian Province (2021J01149)State Key Laboratory of Structural Chemistry (20200007)Sichuan Science and Technology Program (project No.: 2022ZYD0016 and 2023JDRC0013)the National Natural Science Foundation of China (project No. 21776120)。
文摘Lithium–sulfur(Li–S) batteries have received widespread attention, and lean electrolyte Li–S batteries have attracted additional interest because of their higher energy densities. This review systematically analyzes the effect of the electrolyte-to-sulfur(E/S) ratios on battery energy density and the challenges for sulfur reduction reactions(SRR) under lean electrolyte conditions. Accordingly, we review the use of various polar transition metal sulfur hosts as corresponding solutions to facilitate SRR kinetics at low E/S ratios(< 10 μL mg~(-1)), and the strengths and limitations of different transition metal compounds are presented and discussed from a fundamental perspective. Subsequently, three promising strategies for sulfur hosts that act as anchors and catalysts are proposed to boost lean electrolyte Li–S battery performance. Finally, an outlook is provided to guide future research on high energy density Li–S batteries.
文摘This paper presents a study on the design strategy of leaning-type arch bridges.The main characteristics of leaning-type arch bridges are first introduced;Kunshan Yufeng Bridge is taken as an example to discuss different aspects of a design strategy,which includes self-system optimization,selection of beam length and bridge deck position,and other aspects.This paper can be used as a reference to further improve and develop bridge design.
文摘目的研究集中管理模式下精益六西格玛(lean six sigma,LSS)管理法在优化生命支持类医疗设备维修管理流程方面的应用价值。方法以输液泵和注射泵为例,运用LSS管理方法中的界定、测量、分析、改进和控制5个阶段流程对生命支持类医疗设备维修管理难点进行分析,采用组织系统模型流程管理及鱼骨图等方法,分析影响设备维修管理的关键环节,提出在集中管理模式中简化维修审批流程、建立集中管理设备维修和质量控制运行机制、规范设备消毒和检测制度等改进方案,对LSS管理方法实施前后输液泵和注射泵实际维修周期和维修费用进行比较。结果LSS管理方法实施后,输液泵和注射泵设备实际维修时长分别缩短至(6.75±1.81)d和(5.89±1.25)d,维修周期分别缩短26.87%和20.19%,差异有统计学意义(P<0.05);输液泵和注射泵每月单次维修费用分别降低至232.10[32.50,291.00]元和164.40[32.80,183.40]元,差异有统计学意义(P<0.05);月均维修费用分别降低至1217.00元和1426.75元,分别降低了16.54%和28.20%,达到了LSS管理方法的工作目标。结论本研究提出的LSS管理方法可以有效分析医疗设备维修管理中的难点,从而在集中管理模式下针对性优化管理流程,可有效提升设备维修效率,降低维修成本。
