Mass Customization and global economic collaboration drives the product development and management beyond internal enterprise to cover the whole product value chain. To meet such requirement, a strategy approach focus...Mass Customization and global economic collaboration drives the product development and management beyond internal enterprise to cover the whole product value chain. To meet such requirement, a strategy approach focusing on data organization for product lifecycle management was promoted. The approach takes product platform as the base, view engine and rule-based access as data access mechanism, and integration and collaboration bus as a enabler to allow participants involved in product lifecycle to get convenient, WEB-based access to the internal and external content, applications, and services.展开更多
Engineering Change (EC) management for a Product Lifecycle Management (PLM) system, including EC data model, EC evaluation and EC implementation is presented. A method of dynamic and parallel EC evaluation is proposed...Engineering Change (EC) management for a Product Lifecycle Management (PLM) system, including EC data model, EC evaluation and EC implementation is presented. A method of dynamic and parallel EC evaluation is proposed, which breaks an EC evaluation task into several subtasks. Such subtasks can be dynamically and simultaneously proceeded, disassembled and communicated by different specialists, and at the same time a set of EC objects is created. This approach provides flexible and effective evaluation of the EC. The EC implementation followed will further ensure the completeness and consistency of EC data.展开更多
Project management teams are critical in the implementation of megaprojects,but their evolution throughout the project lifecycle has not been clearly explained.This paper explores the organizational evolution of megap...Project management teams are critical in the implementation of megaprojects,but their evolution throughout the project lifecycle has not been clearly explained.This paper explores the organizational evolution of megaproject management teams through a longitudinal retrospective case study of the Hong Kong–Zhuhai–Macao Bridge(HZMB)project.The organizational evolution is examined in terms of management objectives,management content,and organizational structure.The organizational evolution of the HZMB project management team exhibits stage differentiation with the coexistence of turbulence and stability.Changes in the external environment are the driving force for organizational evolution,whereas a flexible organizational strategy is critical in promoting this evolution.Basing on the HZMB case study,this paper summarizes six critical measures that facilitate the organizational evolution of megaproject management teams.Our findings add value to megaproject management theory and provide a better understanding of the dynamics and complexity of megaproject organizational management.展开更多
CDMOs are emerging as critical drivers of innovation within the pharmaceutical and biotech industries. As the pharmaceutical industry continues to evolve, we can expect to see CDMOs play an increasingly important role...CDMOs are emerging as critical drivers of innovation within the pharmaceutical and biotech industries. As the pharmaceutical industry continues to evolve, we can expect to see CDMOs play an increasingly important role in drug development and manufacturing. Many companies within these sectors are now leveraging the expertise of CDMOs through technology transfers to foster innovation and enhance the development of new drug products. In the extensive field of drug development, technology transfer plays a crucial role at multiple stages, ranging from preclinical phases to commercialization. By working closely with drug developers, CDMOs can ensure that technologies are transferred seamlessly between phases of drug development, allowing for a more efficient and cost-effective development process. CDMOs also bring a wealth of experience in various areas of drug development, including process development, analytical testing, quality control, and manufacturing. This expertise, combined with a focus on innovation, can help drug developers to overcome technical challenges and optimize their drug development programs. CDMOs can provide drug developers with various manufacturing capabilities, from small-scale clinical trials to large-scale commercial production. This flexibility allows drug developers to focus on their core competencies while relying on CDMOs to provide the necessary infrastructure and support for drug manufacturing. The critical role of CDMOs in advancing pharmaceutical innovation in phase-appropriate technology transfer where there will be a lot of effort and patience with strong technical expertise is required. This article explores the various types of Technology transfer from preclinical to commercial stages and successful strategies to foster innovation.展开更多
Modular technology can effectively support the rapid design of products, and it is one of the key technologies to realize mass customization design. With the application of product lifecycle management(PLM) system in ...Modular technology can effectively support the rapid design of products, and it is one of the key technologies to realize mass customization design. With the application of product lifecycle management(PLM) system in enterprises, the product lifecycle data have been effectively managed. However, these data have not been fully utilized in module division, especially for complex machinery products. To solve this problem, a product module mining method for the PLM database is proposed to improve the effect of module division. Firstly, product data are extracted from the PLM database by data extraction algorithm. Then, data normalization and structure logical inspection are used to preprocess the extracted defective data. The preprocessed product data are analyzed and expressed in a matrix for module mining. Finally, the fuzzy c-means clustering(FCM) algorithm is used to generate product modules, which are stored in product module library after module marking and post-processing. The feasibility and effectiveness of the proposed method are verified by a case study of high pressure valve.展开更多
Over last few years, web services, Java 2 and XML have provided the cheaper means for trading partners to make use of EDI. It is now possible to share data with less reliance on expensive dedicated EDI networks. The s...Over last few years, web services, Java 2 and XML have provided the cheaper means for trading partners to make use of EDI. It is now possible to share data with less reliance on expensive dedicated EDI networks. The second comes the realization that Product Definition can be reused by virtually all business processes downstream. This has made collaborative product development a practical reality. These technologies have enabled effective implementation of Product Lifecycle Management (PLM) Solutions. This paper presents a literature review about PLM solutions, looking at its definitions, through to its need and scope of applications. It also presents the most generally envisaged architecture, explaining as to how it may be looked at and what it is expected to deliver. At the end it examines the market trend and revenue growth over recent years including future trends for the most prominent vendors pitched in the field of PLM solutions.展开更多
As the global population continues to grow,the enormous stress on our environment and resources is becoming impossible to ignore.A focus on producing and consuming as cheaply as possible has created an economy in whic...As the global population continues to grow,the enormous stress on our environment and resources is becoming impossible to ignore.A focus on producing and consuming as cheaply as possible has created an economy in which objects are briefly used and then discarded as waste,featuring a linear lifecycle that creates an enormous amount of waste.The alternative to the linear economy“take-make-waste”is called the“circular economy”.Under this paradigm,materials are recycled to build new products or components that are designed and built to promote their reuse and refurbishment.This assures the continuous(re-)exploitation of existing resources,reducing the extraction of new raw materials.However,customers often reject these reused or refurbished products under the suspicion that they do not meet the same usability,safety,or performance levels of new products.In this sense,trustworthy records of historical details of refurbished products could increase consumers’confidence in products and components of the“circular economy”,prioritizing trustworthiness,reliability,and transparency.This work presents a new certification tool based on blockchain technology to guarantee trusted,accurate,transparent,and traceable lifecycle information of products and their components and to generate trustworthy certificates to probe refurbished product historical details.This tool aims to enhance refurbished product visibility by creating the basis for making the circular economy a reality in any domain.展开更多
The digital transformation of the built asset industry is moving toward closer integration of physical and digital assets and resources.Within the framework of Cyber-Physical Systems(CPSs)and Digital Twins(DTs),an inc...The digital transformation of the built asset industry is moving toward closer integration of physical and digital assets and resources.Within the framework of Cyber-Physical Systems(CPSs)and Digital Twins(DTs),an increasing number of studies focus on the technical aspects of CPS and DT.However,a unified framework describing the dimensions and characteristics essential for integrating lifecycle information remains elusive.To leverage these concepts effectively,it is necessary to develop new frameworks to classify and put into relationship various components that comprise the lifecycle information integration of physical and digital assets and resources.This paper addresses these gaps by proposing a taxonomy of Built Asset Lifecycle Information Couples,which outlines the dimensions and characteristics crucial for the lifecycle information integration of built assets and resources.The proposed taxonomy contributes to the efforts aimed at organizing the knowledge domain of lifecycle information management in the built environment.展开更多
Blockchain technology is considered one of the promising technologies of the information technology era.The core features of blockchain,such as decentralization,transparency,high security,and tamper-proof nature,bring...Blockchain technology is considered one of the promising technologies of the information technology era.The core features of blockchain,such as decentralization,transparency,high security,and tamper-proof nature,bring great convenience for large-scale social cooperation and data sharing.Blockchain has a broad application prospect in the field of intelligent manufacturing.The key issues of this field,such as distributed collaborative production,industrial big data sharing and security,transparent logistics,and supply chain,are naturally consistent with the core characteristics of the blockchain technology.This study aims to analyze the application of blockchain in the field of intelligent manufacturing.First,we introduce the basic connotation and applications of blockchain.Then,we propose the theoretical basis for the application of blockchain in the field of intelligent manufacturing.Finally,we point out the realistic plights and provide some suggestions to promote the application of blockchain in the field of intelligent manufacturing.展开更多
文摘Mass Customization and global economic collaboration drives the product development and management beyond internal enterprise to cover the whole product value chain. To meet such requirement, a strategy approach focusing on data organization for product lifecycle management was promoted. The approach takes product platform as the base, view engine and rule-based access as data access mechanism, and integration and collaboration bus as a enabler to allow participants involved in product lifecycle to get convenient, WEB-based access to the internal and external content, applications, and services.
基金Supported by Fujian Province Natural Science Foundation (A04400066)Xiamen Science and Technology Program(3502Z20055028)
文摘Engineering Change (EC) management for a Product Lifecycle Management (PLM) system, including EC data model, EC evaluation and EC implementation is presented. A method of dynamic and parallel EC evaluation is proposed, which breaks an EC evaluation task into several subtasks. Such subtasks can be dynamically and simultaneously proceeded, disassembled and communicated by different specialists, and at the same time a set of EC objects is created. This approach provides flexible and effective evaluation of the EC. The EC implementation followed will further ensure the completeness and consistency of EC data.
基金This work was supported by the National Natural Science Foundation of China(Grant No.72001051)Guangdong Philosophical and Social Science Program(Grant No.GD19YGL09)National Philosophical and Social Science Foundation of China(Grant No.18ZDA043).
文摘Project management teams are critical in the implementation of megaprojects,but their evolution throughout the project lifecycle has not been clearly explained.This paper explores the organizational evolution of megaproject management teams through a longitudinal retrospective case study of the Hong Kong–Zhuhai–Macao Bridge(HZMB)project.The organizational evolution is examined in terms of management objectives,management content,and organizational structure.The organizational evolution of the HZMB project management team exhibits stage differentiation with the coexistence of turbulence and stability.Changes in the external environment are the driving force for organizational evolution,whereas a flexible organizational strategy is critical in promoting this evolution.Basing on the HZMB case study,this paper summarizes six critical measures that facilitate the organizational evolution of megaproject management teams.Our findings add value to megaproject management theory and provide a better understanding of the dynamics and complexity of megaproject organizational management.
文摘CDMOs are emerging as critical drivers of innovation within the pharmaceutical and biotech industries. As the pharmaceutical industry continues to evolve, we can expect to see CDMOs play an increasingly important role in drug development and manufacturing. Many companies within these sectors are now leveraging the expertise of CDMOs through technology transfers to foster innovation and enhance the development of new drug products. In the extensive field of drug development, technology transfer plays a crucial role at multiple stages, ranging from preclinical phases to commercialization. By working closely with drug developers, CDMOs can ensure that technologies are transferred seamlessly between phases of drug development, allowing for a more efficient and cost-effective development process. CDMOs also bring a wealth of experience in various areas of drug development, including process development, analytical testing, quality control, and manufacturing. This expertise, combined with a focus on innovation, can help drug developers to overcome technical challenges and optimize their drug development programs. CDMOs can provide drug developers with various manufacturing capabilities, from small-scale clinical trials to large-scale commercial production. This flexibility allows drug developers to focus on their core competencies while relying on CDMOs to provide the necessary infrastructure and support for drug manufacturing. The critical role of CDMOs in advancing pharmaceutical innovation in phase-appropriate technology transfer where there will be a lot of effort and patience with strong technical expertise is required. This article explores the various types of Technology transfer from preclinical to commercial stages and successful strategies to foster innovation.
基金Project(51275362)supported by the National Natural Science Foundation of ChinaProject(2013M542055)supported by China Postdoctoral Science Foundation Funded
文摘Modular technology can effectively support the rapid design of products, and it is one of the key technologies to realize mass customization design. With the application of product lifecycle management(PLM) system in enterprises, the product lifecycle data have been effectively managed. However, these data have not been fully utilized in module division, especially for complex machinery products. To solve this problem, a product module mining method for the PLM database is proposed to improve the effect of module division. Firstly, product data are extracted from the PLM database by data extraction algorithm. Then, data normalization and structure logical inspection are used to preprocess the extracted defective data. The preprocessed product data are analyzed and expressed in a matrix for module mining. Finally, the fuzzy c-means clustering(FCM) algorithm is used to generate product modules, which are stored in product module library after module marking and post-processing. The feasibility and effectiveness of the proposed method are verified by a case study of high pressure valve.
基金Sponsored by Ministry of Education PR China (Grant No.20020006012)
文摘Over last few years, web services, Java 2 and XML have provided the cheaper means for trading partners to make use of EDI. It is now possible to share data with less reliance on expensive dedicated EDI networks. The second comes the realization that Product Definition can be reused by virtually all business processes downstream. This has made collaborative product development a practical reality. These technologies have enabled effective implementation of Product Lifecycle Management (PLM) Solutions. This paper presents a literature review about PLM solutions, looking at its definitions, through to its need and scope of applications. It also presents the most generally envisaged architecture, explaining as to how it may be looked at and what it is expected to deliver. At the end it examines the market trend and revenue growth over recent years including future trends for the most prominent vendors pitched in the field of PLM solutions.
文摘As the global population continues to grow,the enormous stress on our environment and resources is becoming impossible to ignore.A focus on producing and consuming as cheaply as possible has created an economy in which objects are briefly used and then discarded as waste,featuring a linear lifecycle that creates an enormous amount of waste.The alternative to the linear economy“take-make-waste”is called the“circular economy”.Under this paradigm,materials are recycled to build new products or components that are designed and built to promote their reuse and refurbishment.This assures the continuous(re-)exploitation of existing resources,reducing the extraction of new raw materials.However,customers often reject these reused or refurbished products under the suspicion that they do not meet the same usability,safety,or performance levels of new products.In this sense,trustworthy records of historical details of refurbished products could increase consumers’confidence in products and components of the“circular economy”,prioritizing trustworthiness,reliability,and transparency.This work presents a new certification tool based on blockchain technology to guarantee trusted,accurate,transparent,and traceable lifecycle information of products and their components and to generate trustworthy certificates to probe refurbished product historical details.This tool aims to enhance refurbished product visibility by creating the basis for making the circular economy a reality in any domain.
文摘The digital transformation of the built asset industry is moving toward closer integration of physical and digital assets and resources.Within the framework of Cyber-Physical Systems(CPSs)and Digital Twins(DTs),an increasing number of studies focus on the technical aspects of CPS and DT.However,a unified framework describing the dimensions and characteristics essential for integrating lifecycle information remains elusive.To leverage these concepts effectively,it is necessary to develop new frameworks to classify and put into relationship various components that comprise the lifecycle information integration of physical and digital assets and resources.This paper addresses these gaps by proposing a taxonomy of Built Asset Lifecycle Information Couples,which outlines the dimensions and characteristics crucial for the lifecycle information integration of built assets and resources.The proposed taxonomy contributes to the efforts aimed at organizing the knowledge domain of lifecycle information management in the built environment.
基金the National Natural Science Foundation of China(Grant Nos.71690230,71690235,and 71501055).
文摘Blockchain technology is considered one of the promising technologies of the information technology era.The core features of blockchain,such as decentralization,transparency,high security,and tamper-proof nature,bring great convenience for large-scale social cooperation and data sharing.Blockchain has a broad application prospect in the field of intelligent manufacturing.The key issues of this field,such as distributed collaborative production,industrial big data sharing and security,transparent logistics,and supply chain,are naturally consistent with the core characteristics of the blockchain technology.This study aims to analyze the application of blockchain in the field of intelligent manufacturing.First,we introduce the basic connotation and applications of blockchain.Then,we propose the theoretical basis for the application of blockchain in the field of intelligent manufacturing.Finally,we point out the realistic plights and provide some suggestions to promote the application of blockchain in the field of intelligent manufacturing.
