Background Urethroplasty of complex urethral stricture is a difficult procedure, and there is no widely accepted standard approach described in the published literature. We evaluated the efficacy and safety of urethro...Background Urethroplasty of complex urethral stricture is a difficult procedure, and there is no widely accepted standard approach described in the published literature. We evaluated the efficacy and safety of urethroplasty using lingual mucosa grafts （LMGs） for the repair of urethral strictures. Methods Between August 2006 and April 2009, 92 cases of urethral strictures （length ranging from 2.5 cm to 18 cm, mean 6.5 cm） were treated using LMGs. Of the 92 patients, 38 with long-segment urethral strictures （9-18 cm） underwent dual LMG or LMG combined with foreskin flap or buccal mucosal graft urethroplasty. Results Follow-up was obtained for 3-33 months （mean 17.2 months） postoperatively. Complications occurred in 8 patients, including urinary fistulas in 4 patients; recurrent strictures developed in 4 patients at 3-4 months post-operatively. The remaining patients voided well postoperatively, with peak flows between 14.3 ml/s and 54.6 ml/s （mean 28.4 ml/s）. Conclusions The tongue is an excellent source of graft material for the repair of anterior mucosal strictures. Dual LMG substitution urethroplasty can successfully treat longer, more complex urethral strictures.展开更多
The aim of this study was to retrospectively investigate the outcomes of patients who underwent one-stage onlay or inlay urethroplasty using a lingual mucosal graft （LMG） after failed hypospadias repairs. Inclusion ...The aim of this study was to retrospectively investigate the outcomes of patients who underwent one-stage onlay or inlay urethroplasty using a lingual mucosal graft （LMG） after failed hypospadias repairs. Inclusion criteria included a history of failed hypospadias repair, insufficiency of the local skin that made a reoperation with skin flaps difficult, and necessity of an oral mucosal graft urethroplasty. Patients were excluded if they had undergone a failed hypospadias repair using the foreskin or a multistage repair urethroplasty. Between January 2008 and December 2012, 110 patients with failed hypospadias repairs were treated in our center. Of these patients, 56 underwent a one-stage onlay or inlay urethroplasty using LMG. The median age was 21.8 years （range： 4-45 years）. Of the 56 patients, one-stage onlay LMG urethroplasty was performed in 42 patients （group 1）, and a modified Snodgrass technique using one-stage inlay LMG urethroplasty was performed in 14 （group 2）. The median LMG urethroplasty length was 5.6 ± 1.6 cm （range： 4-13 cm）. The mean follow-up was 34.7 months （range： 10-58 months）, and complications developed in 12 of 56 patients （21.4%）, including urethrocutaneous fistulas in 7 （6 in group 1, 1 in group 2） and neourethral strictures in 5 （4 in group 1, 1 in group 2）. The total success rate was 78.6%. Our survey suggests that one-stage onlay or inlay urethroplasty with LMG may be an effective option to treat the patients with less available skin after failed hypospadias repairs; LMG harvesting is easy and safe, irrespective of the patient＇s age.展开更多
目的观察非离断尿道海绵体技术结合舌黏膜扩大管腔在男性球部尿道狭窄修复重建中的疗效及并发症。方法男性球部尿道狭窄患者21例,分离出球部狭窄段尿道后,不离断尿道海绵体,纵向剖开尿道管腔,其中尿道狭窄长度在2 cm以内12例,直接行勺...目的观察非离断尿道海绵体技术结合舌黏膜扩大管腔在男性球部尿道狭窄修复重建中的疗效及并发症。方法男性球部尿道狭窄患者21例,分离出球部狭窄段尿道后,不离断尿道海绵体,纵向剖开尿道管腔,其中尿道狭窄长度在2 cm以内12例,直接行勺状尿道端端吻合。其中尿道狭窄段长度超过2 cm 9例,考虑直接尿道吻合张力大,应用舌黏膜作为修复材料,行尿道加盖扩大尿道管腔,观察所有病例疗效及尿道瘘、尿道狭窄和勃起功能障碍等相关并发症的发生率。所有患者术前经RigiScan检测夜间阴茎勃起硬度和膨胀度,术后1个月再次通过NPTR证实患者是否存在正常勃起。结果所有患者均手术顺利,其中一次手术成功18例(85.71%),无任何并发症发生,舌黏膜尿道成形术后出现严重感染1例,经抗炎、换药、冲洗愈合后出现尿道瘘,6个月后行尿道瘘修补术,愈合良好,排尿通畅。出现阴囊局部血肿1例,经清创,加压包扎以及换药等处理,最终恢复良好。出现会阴部切口裂开1例,经换药、抗炎及红外治疗等处理,最终切口恢复良好,拔除尿管后出现尿道狭窄,经尿道扩张后,可通畅排尿。21例患者无1例术后勃起功能障碍发生。对所有患者进行随访,要求患者能够通畅排尿,并且尿道扩张能够坚持3个月以上。结论非离断尿道海绵体技术结合舌黏膜扩大管腔在球部尿道狭窄修复重建中的临床应用效果肯定,不会增加术后勃起功能障碍的发生率,有临床推广价值。展开更多
文摘Background Urethroplasty of complex urethral stricture is a difficult procedure, and there is no widely accepted standard approach described in the published literature. We evaluated the efficacy and safety of urethroplasty using lingual mucosa grafts （LMGs） for the repair of urethral strictures. Methods Between August 2006 and April 2009, 92 cases of urethral strictures （length ranging from 2.5 cm to 18 cm, mean 6.5 cm） were treated using LMGs. Of the 92 patients, 38 with long-segment urethral strictures （9-18 cm） underwent dual LMG or LMG combined with foreskin flap or buccal mucosal graft urethroplasty. Results Follow-up was obtained for 3-33 months （mean 17.2 months） postoperatively. Complications occurred in 8 patients, including urinary fistulas in 4 patients; recurrent strictures developed in 4 patients at 3-4 months post-operatively. The remaining patients voided well postoperatively, with peak flows between 14.3 ml/s and 54.6 ml/s （mean 28.4 ml/s）. Conclusions The tongue is an excellent source of graft material for the repair of anterior mucosal strictures. Dual LMG substitution urethroplasty can successfully treat longer, more complex urethral strictures.
文摘The aim of this study was to retrospectively investigate the outcomes of patients who underwent one-stage onlay or inlay urethroplasty using a lingual mucosal graft （LMG） after failed hypospadias repairs. Inclusion criteria included a history of failed hypospadias repair, insufficiency of the local skin that made a reoperation with skin flaps difficult, and necessity of an oral mucosal graft urethroplasty. Patients were excluded if they had undergone a failed hypospadias repair using the foreskin or a multistage repair urethroplasty. Between January 2008 and December 2012, 110 patients with failed hypospadias repairs were treated in our center. Of these patients, 56 underwent a one-stage onlay or inlay urethroplasty using LMG. The median age was 21.8 years （range： 4-45 years）. Of the 56 patients, one-stage onlay LMG urethroplasty was performed in 42 patients （group 1）, and a modified Snodgrass technique using one-stage inlay LMG urethroplasty was performed in 14 （group 2）. The median LMG urethroplasty length was 5.6 ± 1.6 cm （range： 4-13 cm）. The mean follow-up was 34.7 months （range： 10-58 months）, and complications developed in 12 of 56 patients （21.4%）, including urethrocutaneous fistulas in 7 （6 in group 1, 1 in group 2） and neourethral strictures in 5 （4 in group 1, 1 in group 2）. The total success rate was 78.6%. Our survey suggests that one-stage onlay or inlay urethroplasty with LMG may be an effective option to treat the patients with less available skin after failed hypospadias repairs; LMG harvesting is easy and safe, irrespective of the patient＇s age.
文摘目的观察非离断尿道海绵体技术结合舌黏膜扩大管腔在男性球部尿道狭窄修复重建中的疗效及并发症。方法男性球部尿道狭窄患者21例,分离出球部狭窄段尿道后,不离断尿道海绵体,纵向剖开尿道管腔,其中尿道狭窄长度在2 cm以内12例,直接行勺状尿道端端吻合。其中尿道狭窄段长度超过2 cm 9例,考虑直接尿道吻合张力大,应用舌黏膜作为修复材料,行尿道加盖扩大尿道管腔,观察所有病例疗效及尿道瘘、尿道狭窄和勃起功能障碍等相关并发症的发生率。所有患者术前经RigiScan检测夜间阴茎勃起硬度和膨胀度,术后1个月再次通过NPTR证实患者是否存在正常勃起。结果所有患者均手术顺利,其中一次手术成功18例(85.71%),无任何并发症发生,舌黏膜尿道成形术后出现严重感染1例,经抗炎、换药、冲洗愈合后出现尿道瘘,6个月后行尿道瘘修补术,愈合良好,排尿通畅。出现阴囊局部血肿1例,经清创,加压包扎以及换药等处理,最终恢复良好。出现会阴部切口裂开1例,经换药、抗炎及红外治疗等处理,最终切口恢复良好,拔除尿管后出现尿道狭窄,经尿道扩张后,可通畅排尿。21例患者无1例术后勃起功能障碍发生。对所有患者进行随访,要求患者能够通畅排尿,并且尿道扩张能够坚持3个月以上。结论非离断尿道海绵体技术结合舌黏膜扩大管腔在球部尿道狭窄修复重建中的临床应用效果肯定,不会增加术后勃起功能障碍的发生率,有临床推广价值。
