[Objective] This study aimed to explore the pharmacognostical features of Brazilian ginseng( Pfaffia paniculata),and to provide a theoretical basis for its development and utilization. [Method] Morphological traits of...[Objective] This study aimed to explore the pharmacognostical features of Brazilian ginseng( Pfaffia paniculata),and to provide a theoretical basis for its development and utilization. [Method] Morphological traits of Brazilian ginseng root were observed with traditional methods. Then,the root,stem and leaf of Brazilian ginseng were sliced,and observed under a microscope. The physical and chemical properties of root extract were detected. [Result] Brazilian ginseng root is elongated and cylindrical,with obvious longitudinal ridges and sparse root marks,some irregularly shaped lenticels on the surface. The cork layer of crosssection has five or more rows of cork cells. The abnormal vascular bundles are arranged in two to three rings. There are two to three central vascular bundles. The wood fibers in powder are long,with one bifurcate end. The vessels have bordered pits. The sand crystals are scattered or in the parenchyma surrounding the fibers.The mucilage cells are oval and widely exist. Physical and chemical experiments showed that the root of Brazilian ginseng contains sterols or triterpenes and saponins. [Conclusion] The results will provide a theoretical basis for the pharmacological identification of Brazilian ginseng.展开更多
At the boundary between pharmacognosy and molecular biology,molecular pharmacognosy has developed as a new borderline discipline.This paper reviews the methods,application,and prospect of molecular pharmacognosy.DNA m...At the boundary between pharmacognosy and molecular biology,molecular pharmacognosy has developed as a new borderline discipline.This paper reviews the methods,application,and prospect of molecular pharmacognosy.DNA marker is one of genetic markers and some molecular marker methods which have been successfully used for genetic diversity identification and new medicinal resources development.Recombinant DNA technology provides a powerful tool that enables scientists to engineer DNA sequences.Gene chip technique could be used in determination of gene expression profiles,analyses of polymorphisms,construction of genomic library,analysis of mapping,and sequencing by hybridization.Using the methods and theory of molecular biology and pharmacognosy,molecular pharmacognosy represents an extremely prospective branch of pharmacognosy and focuses on the study of systemic growth of medicinal plants,identification and evaluation of germplasm resources,plant metabolomics and production of active compounds.Furthermore,the great breakthrough of molecular pharmacognosy could be anticipated on DNA fingerprint analysis,cultivar improvement,DNA identification,and a global DNA barcoding system in the future.展开更多
This article analyzes the background and significance of molecular pharmacognosy,including the molecular identification of medicinal raw materials,phylogenetic evolution of medicinal plants and animals,evaluation and ...This article analyzes the background and significance of molecular pharmacognosy,including the molecular identification of medicinal raw materials,phylogenetic evolution of medicinal plants and animals,evaluation and preservation of germplasm resources for medicinal plants and animals,etiology of endangerment and protection of endangered medicinal plants and animals,biosynthesis and bioregulation of active components in medicinal plants,and characteristics and the molecular bases of top-geoherbs.展开更多
Prof.HUANG Lu-qi was born in Wuyuan county,Jiangxi Province in March,1968. He graduated from Jiangxi University of Traditional Chinese Medicine in 1989, and obtained his Ph.D.in pharmacognosy from the Peking Universit...Prof.HUANG Lu-qi was born in Wuyuan county,Jiangxi Province in March,1968. He graduated from Jiangxi University of Traditional Chinese Medicine in 1989, and obtained his Ph.D.in pharmacognosy from the Peking University Health Science Center in 1995.Prof.展开更多
Different parts of Wrightia tinctoria R.Br.(Apocynaceae)(W.tinctoria),have been extensively used in Indian systems of medicine such as Ayurveda,Siddha and Unani for the treatment of jaundice,malaria,psoriasis and many...Different parts of Wrightia tinctoria R.Br.(Apocynaceae)(W.tinctoria),have been extensively used in Indian systems of medicine such as Ayurveda,Siddha and Unani for the treatment of jaundice,malaria,psoriasis and many other ailments.The present review has been primed to describe the existing data on the information on the traditional uses,botany,pharmacognosy,phytochemical constituents,pharmacological activities and toxicology of W.tinctoria.The information was gathered via electronic search(using Google Scholar,NOPR,Pubmed,Elsevier,Medline Plus and Web of Science)and library search for the books on traditional medicine as well as the articles published in peer-reviewed journals.The plant is rich in compounds containing alkaloids,saponins,indoxy yielding O-glycoside(s),phenolics,flavonoids,isatin tryptanthrin,anthranillate,rutin,β-isatin,tryptophan,indigotin,indirubin,wrightial and sterols.The vast number of literature found in database revealed that the extracts of different parts of W.tinctoria showed significant pharmacological actions.Clinical studies indicated a broad range of applications in the treatment of psoriasis and other skin diseases.We suggest that there is a need for further investigations to isolate active principles that confer pharmacological action.Therefore,identification of such active compound is useful for producing safer drugs in the treatments of various ailments.展开更多
基金Supported by Science and Technology Research Project of Guangxi Zhuang Autonomous Region(Gui Ke Gong 14124002-11-1)High-level Innovation Team and Outstanding Scholar Project of Guangxi Higher Education Institutes-Zhuang Medicine Foundation and Clinical Innovation Team(Gui Jiao Ren 201407)Key Laboratory Construction Project of Guangxi Colleges and Universities for Zhuang Medicine Prescriptions Basis and Application Research(Gui Jiao Ke Yan[2016]No.6-zyfy2016)
文摘[Objective] This study aimed to explore the pharmacognostical features of Brazilian ginseng( Pfaffia paniculata),and to provide a theoretical basis for its development and utilization. [Method] Morphological traits of Brazilian ginseng root were observed with traditional methods. Then,the root,stem and leaf of Brazilian ginseng were sliced,and observed under a microscope. The physical and chemical properties of root extract were detected. [Result] Brazilian ginseng root is elongated and cylindrical,with obvious longitudinal ridges and sparse root marks,some irregularly shaped lenticels on the surface. The cork layer of crosssection has five or more rows of cork cells. The abnormal vascular bundles are arranged in two to three rings. There are two to three central vascular bundles. The wood fibers in powder are long,with one bifurcate end. The vessels have bordered pits. The sand crystals are scattered or in the parenchyma surrounding the fibers.The mucilage cells are oval and widely exist. Physical and chemical experiments showed that the root of Brazilian ginseng contains sterols or triterpenes and saponins. [Conclusion] The results will provide a theoretical basis for the pharmacological identification of Brazilian ginseng.
文摘At the boundary between pharmacognosy and molecular biology,molecular pharmacognosy has developed as a new borderline discipline.This paper reviews the methods,application,and prospect of molecular pharmacognosy.DNA marker is one of genetic markers and some molecular marker methods which have been successfully used for genetic diversity identification and new medicinal resources development.Recombinant DNA technology provides a powerful tool that enables scientists to engineer DNA sequences.Gene chip technique could be used in determination of gene expression profiles,analyses of polymorphisms,construction of genomic library,analysis of mapping,and sequencing by hybridization.Using the methods and theory of molecular biology and pharmacognosy,molecular pharmacognosy represents an extremely prospective branch of pharmacognosy and focuses on the study of systemic growth of medicinal plants,identification and evaluation of germplasm resources,plant metabolomics and production of active compounds.Furthermore,the great breakthrough of molecular pharmacognosy could be anticipated on DNA fingerprint analysis,cultivar improvement,DNA identification,and a global DNA barcoding system in the future.
文摘This article analyzes the background and significance of molecular pharmacognosy,including the molecular identification of medicinal raw materials,phylogenetic evolution of medicinal plants and animals,evaluation and preservation of germplasm resources for medicinal plants and animals,etiology of endangerment and protection of endangered medicinal plants and animals,biosynthesis and bioregulation of active components in medicinal plants,and characteristics and the molecular bases of top-geoherbs.
文摘Prof.HUANG Lu-qi was born in Wuyuan county,Jiangxi Province in March,1968. He graduated from Jiangxi University of Traditional Chinese Medicine in 1989, and obtained his Ph.D.in pharmacognosy from the Peking University Health Science Center in 1995.Prof.
文摘Different parts of Wrightia tinctoria R.Br.(Apocynaceae)(W.tinctoria),have been extensively used in Indian systems of medicine such as Ayurveda,Siddha and Unani for the treatment of jaundice,malaria,psoriasis and many other ailments.The present review has been primed to describe the existing data on the information on the traditional uses,botany,pharmacognosy,phytochemical constituents,pharmacological activities and toxicology of W.tinctoria.The information was gathered via electronic search(using Google Scholar,NOPR,Pubmed,Elsevier,Medline Plus and Web of Science)and library search for the books on traditional medicine as well as the articles published in peer-reviewed journals.The plant is rich in compounds containing alkaloids,saponins,indoxy yielding O-glycoside(s),phenolics,flavonoids,isatin tryptanthrin,anthranillate,rutin,β-isatin,tryptophan,indigotin,indirubin,wrightial and sterols.The vast number of literature found in database revealed that the extracts of different parts of W.tinctoria showed significant pharmacological actions.Clinical studies indicated a broad range of applications in the treatment of psoriasis and other skin diseases.We suggest that there is a need for further investigations to isolate active principles that confer pharmacological action.Therefore,identification of such active compound is useful for producing safer drugs in the treatments of various ailments.
