BACKGROUND: It has been proved that brain electrical activity mapping (BEAM) and transcranial Doppler (TCD) detection can reflect the function of brain cell and its diseased degree of infant patients with moderate to ...BACKGROUND: It has been proved that brain electrical activity mapping (BEAM) and transcranial Doppler (TCD) detection can reflect the function of brain cell and its diseased degree of infant patients with moderate to severe hypoxic-ischemic encephalopathy (HIE).OBJECTIVE: To observe the abnormal results of HIE at different degrees detected with BEAM and TCD in infant patients, and compare the detection results at the same time point between BEAM, TCD and computer tomography (CT) examinations.DESIGN: Contrast observation.SETTING: Departments of Neuro-electrophysiology and Pediatrics, Second Affiliated Hospital of Qiqihar Medical College.PARTICIPANTS: Totally 416 infant patients with HIE who received treatment in the Department of Newborn Infants, Second Affiliated Hospital of Qiqihar Medical College during January 2001 and December 2005. The infant patients, 278 male and 138 female, were at embryonic 37 to 42 weeks and weighing 2.0 to 4.1 kg, and they were diagnosed with CT and met the diagnostic criteria of HIE of newborn infants compiled by Department of Neonatology, Pediatric Academy, Chinese Medical Association. According to diagnostic criteria, 130 patients were mild abnormal, 196 moderate abnormal and 90 severe abnormal. The relatives of all the infant patients were informed of the experiment. METHODS: BEAM and TCD examinations were performed in the involved 416 infant patients with HIE at different degrees with DYD2000 16-channel BEAM instrument and EME-2000 ultrasonograph before preliminary diagnosis treatment (within 1 month after birth) and 1,3,6,12 and 24 months after birth, and detected results were compared between BEAM, TCD and CT examinations. MAIN OUTCOME MEASURES: Comparison of detection results of HIE at different time points in infant patients between BEAM, TCD and CT examinations.RESULTS: All the 416 infant patients with HIE participated in the result analysis. ① Comparison of the detected results in infant patients with mild HIE at different time points after birth between BEAM, TCD and CT examinations: BEAM examination showed that the recovery was delayed, and the abnormal rate of BEAM examination was significantly higher than that of CT examination 1 and 3 months after birth [55.4%(72/130)vs. 17.0%(22/130),χ2=41.66;29.2%(38/130) vs. 6.2%(8/130),χ2=23.77,P < 0.01], exceptional patients had mild abnormality and reached the normal level in about 6 months. TCD examination showed that the disease condition significantly improved and infant patients with HIE basically recovered 1 or 2 months after birth, while CT examination showed that infant patients recovered 3 or 4 months after birth. ② Comparison of detection results of infant patients with moderate HIE at different time points between BEAM, TCD and CT examinations: The abnormal rate of BEAM examination was significantly higher than that of CT examination 1,3,6 and 12 months after birth [90.8%(178/196),78.6%(154/196),χ2=4.32,P < 0.05;64.3%(126/196),43.9%(86/196),χ2=16.44;44.9%(88/196),22.4%(44/196),χ2=22.11;21.4%(42/196),10.2%(20/196),χ2=9.27,P < 0.01]. BEAM examination showed that there was still one patient who did not completely recovered in the 24th month due to the relatives of infant patients did not combine the treatment,. TCD examination showed that the abnormal rate was 23.1%(30/196)in the 1st month after birth, and all the patients recovered to the normal in the 3rd month after birth, while CT examination showed that mild abnormality still existed in the 24th month after birth(1.0%,2/196). ③ Comparison of detection results of infant patients with severe HIE at different time points between BEAM, TCD and CT examinations: The abnormal rate of BEAM examination was significantly higher than that of CT examination in the 1st, 3rd, 6th and 12th months after birth[86.7%(78/90),44.4%(40/90),χ2=35.53;62.2%(56/90),31.1%(28/90),χ2=17.51;37.8%(34/90),6.7%(6/90),χ2=27.14,P < 0.01]. BEAM examination showed that mild abnormality still existed in 4 infant patients in the 24th month after birth. TCD examination showed that the abnormal rate was 11.1% (10/90) in the 3rd month after birth, and all the infant patients recovered in the 6th month after birth. CT examination showed that the abnormal rate was 6.7%(6/90) in the 12th month after birth, and all of infant patients recovered to the normal in the 24th month after birth.CONCLUSION: BEAM is the direct index to detect brain function of infant patients with HIE, and positive reaction is still very sensitive in the tracking detection of convalescent period. The positive rate of morphological reaction in CT examination is superior to that in TCD examination, and the positive rate is very high in the acute period of HIE in examination.展开更多
BACKGROUND The main treatment methods for cancer include surgery,radiotherapy,chemotherapy,targeted drug therapy and so on.Patients often feel anger,anxiety,depression,and other negative psychological reactions in the...BACKGROUND The main treatment methods for cancer include surgery,radiotherapy,chemotherapy,targeted drug therapy and so on.Patients often feel anger,anxiety,depression,and other negative psychological reactions in the process of treatment.AIM To explore the effects of cognitive behavioral therapy on the personality characteristics of cancer patients.METHODS According to the matching design requirements,150 cancer patients were divided into 3 groups based on sex,age,condition,and cultural background.Patients in the control group received conventional treatment.Patients in experimental group 1 received an intervention based on conventional treatment combined with cognitive behavioral therapy.Patients in experimental group 2 received family members'participation in addition to the treatment given in experimental group 1.An Eysenck personality questionnaire was used to investigate all the patients before and after the intervention,and the scores for psychosis,introversion,neuroticism,and concealment degree were analyzed.RESULTS Compared with the control group,for experimental group 1 and experimental group 2 before and after the intervention,the four dimensions of mental quality,neuroticism,introversion and concealment degree all decreased,and the difference was statistically significant(P<0.05).After the intervention,there were no obvious or statistically significant differences(P>0.05)among the control group,experimental group 1,and experimental group 2 for two personality traits,psychoticism and neuroticism,both inside and outside degree and all four dimensions.CONCLUSION Simple cognitive behavioral therapy could not change the personality characteristics of cancer patients quickly,but the patients’personality characteristics were significantly improved after treatment.展开更多
Partial cooperation formulation is a more viable option than optimistic's and pessimistic's to solve an ill-posed bilevel programming problem.Aboussoror's partial cooperation model uses a constant as a coo...Partial cooperation formulation is a more viable option than optimistic's and pessimistic's to solve an ill-posed bilevel programming problem.Aboussoror's partial cooperation model uses a constant as a cooperation index to describe the degree of follower's cooperation.The constant only indicates the leader's expectation coefficient for the follower's action,not the follower's own willingness.To solve this situation,a new model is proposed by using the follower's satisfactory degree as the cooperation degree.Then,because this new cooperation degree is a function which is dependent on the leader's choice and decided by the follower's satisfactory degree,this paper proves such proposed model not only leads an optimal value between the optimistic value and pessimistic's,but also leads a more satisfactory solution than Aboussoror's.Finally,a numerical experiment is given to demonstrate the feasibility of this new model.展开更多
Satisficing control remains an important concept in decision making.In this paper,a new epistemic utility satisficing control theory is proposed for a new model of complex CMMO(constrained multi-objective multi degree...Satisficing control remains an important concept in decision making.In this paper,a new epistemic utility satisficing control theory is proposed for a new model of complex CMMO(constrained multi-objective multi degree-of-freedom optimization)system.As well,an epistemic utility function is developed and used to adjust the feasible region of soft constraints.The theory proved in this paper indicates that the utility function not only expresses the subjectivity of the original satisfactory-degree function,but also takes the cost of searching for a solution into account.Thus,the satisfactory-degree function can be adjusted and its rationality can be validated.This theory contributes an analytical method to the inverse satisfactory optimization problem.The findings indicate that this theory has good convergence and outcomes desired for satisfactory-degree functions.展开更多
This paper systematically proposes basic requirements on normalization of comprehensive evaluation system with complex uncertain information due to human participation. Four basic academic ideas are as follows: 1) It ...This paper systematically proposes basic requirements on normalization of comprehensive evaluation system with complex uncertain information due to human participation. Four basic academic ideas are as follows: 1) It is necessary to normalize conditions of information acquisition. 2) The effectiveness of comprehensive evaluation depends on the correctness of information acquisition. 3) Any evaluation results can be transformed into linguistic satisfactory degrees. 4) Linguistic values can include a great deal of information. This paper mainly deals with how to select objects to be evaluated, evaluators (panelists) and the methods of information processing, how to construct criteria of evaluation, how to normalize terms of evaluation, the results of evaluation, and the procedure of evaluation.展开更多
文摘BACKGROUND: It has been proved that brain electrical activity mapping (BEAM) and transcranial Doppler (TCD) detection can reflect the function of brain cell and its diseased degree of infant patients with moderate to severe hypoxic-ischemic encephalopathy (HIE).OBJECTIVE: To observe the abnormal results of HIE at different degrees detected with BEAM and TCD in infant patients, and compare the detection results at the same time point between BEAM, TCD and computer tomography (CT) examinations.DESIGN: Contrast observation.SETTING: Departments of Neuro-electrophysiology and Pediatrics, Second Affiliated Hospital of Qiqihar Medical College.PARTICIPANTS: Totally 416 infant patients with HIE who received treatment in the Department of Newborn Infants, Second Affiliated Hospital of Qiqihar Medical College during January 2001 and December 2005. The infant patients, 278 male and 138 female, were at embryonic 37 to 42 weeks and weighing 2.0 to 4.1 kg, and they were diagnosed with CT and met the diagnostic criteria of HIE of newborn infants compiled by Department of Neonatology, Pediatric Academy, Chinese Medical Association. According to diagnostic criteria, 130 patients were mild abnormal, 196 moderate abnormal and 90 severe abnormal. The relatives of all the infant patients were informed of the experiment. METHODS: BEAM and TCD examinations were performed in the involved 416 infant patients with HIE at different degrees with DYD2000 16-channel BEAM instrument and EME-2000 ultrasonograph before preliminary diagnosis treatment (within 1 month after birth) and 1,3,6,12 and 24 months after birth, and detected results were compared between BEAM, TCD and CT examinations. MAIN OUTCOME MEASURES: Comparison of detection results of HIE at different time points in infant patients between BEAM, TCD and CT examinations.RESULTS: All the 416 infant patients with HIE participated in the result analysis. ① Comparison of the detected results in infant patients with mild HIE at different time points after birth between BEAM, TCD and CT examinations: BEAM examination showed that the recovery was delayed, and the abnormal rate of BEAM examination was significantly higher than that of CT examination 1 and 3 months after birth [55.4%(72/130)vs. 17.0%(22/130),χ2=41.66;29.2%(38/130) vs. 6.2%(8/130),χ2=23.77,P < 0.01], exceptional patients had mild abnormality and reached the normal level in about 6 months. TCD examination showed that the disease condition significantly improved and infant patients with HIE basically recovered 1 or 2 months after birth, while CT examination showed that infant patients recovered 3 or 4 months after birth. ② Comparison of detection results of infant patients with moderate HIE at different time points between BEAM, TCD and CT examinations: The abnormal rate of BEAM examination was significantly higher than that of CT examination 1,3,6 and 12 months after birth [90.8%(178/196),78.6%(154/196),χ2=4.32,P < 0.05;64.3%(126/196),43.9%(86/196),χ2=16.44;44.9%(88/196),22.4%(44/196),χ2=22.11;21.4%(42/196),10.2%(20/196),χ2=9.27,P < 0.01]. BEAM examination showed that there was still one patient who did not completely recovered in the 24th month due to the relatives of infant patients did not combine the treatment,. TCD examination showed that the abnormal rate was 23.1%(30/196)in the 1st month after birth, and all the patients recovered to the normal in the 3rd month after birth, while CT examination showed that mild abnormality still existed in the 24th month after birth(1.0%,2/196). ③ Comparison of detection results of infant patients with severe HIE at different time points between BEAM, TCD and CT examinations: The abnormal rate of BEAM examination was significantly higher than that of CT examination in the 1st, 3rd, 6th and 12th months after birth[86.7%(78/90),44.4%(40/90),χ2=35.53;62.2%(56/90),31.1%(28/90),χ2=17.51;37.8%(34/90),6.7%(6/90),χ2=27.14,P < 0.01]. BEAM examination showed that mild abnormality still existed in 4 infant patients in the 24th month after birth. TCD examination showed that the abnormal rate was 11.1% (10/90) in the 3rd month after birth, and all the infant patients recovered in the 6th month after birth. CT examination showed that the abnormal rate was 6.7%(6/90) in the 12th month after birth, and all of infant patients recovered to the normal in the 24th month after birth.CONCLUSION: BEAM is the direct index to detect brain function of infant patients with HIE, and positive reaction is still very sensitive in the tracking detection of convalescent period. The positive rate of morphological reaction in CT examination is superior to that in TCD examination, and the positive rate is very high in the acute period of HIE in examination.
基金Supported by Science and Technology Foundation of the Guizhou Health Department,No.GZWKJ2011-1-026National Natural Science Foundation of China,No.81760548.
文摘BACKGROUND The main treatment methods for cancer include surgery,radiotherapy,chemotherapy,targeted drug therapy and so on.Patients often feel anger,anxiety,depression,and other negative psychological reactions in the process of treatment.AIM To explore the effects of cognitive behavioral therapy on the personality characteristics of cancer patients.METHODS According to the matching design requirements,150 cancer patients were divided into 3 groups based on sex,age,condition,and cultural background.Patients in the control group received conventional treatment.Patients in experimental group 1 received an intervention based on conventional treatment combined with cognitive behavioral therapy.Patients in experimental group 2 received family members'participation in addition to the treatment given in experimental group 1.An Eysenck personality questionnaire was used to investigate all the patients before and after the intervention,and the scores for psychosis,introversion,neuroticism,and concealment degree were analyzed.RESULTS Compared with the control group,for experimental group 1 and experimental group 2 before and after the intervention,the four dimensions of mental quality,neuroticism,introversion and concealment degree all decreased,and the difference was statistically significant(P<0.05).After the intervention,there were no obvious or statistically significant differences(P>0.05)among the control group,experimental group 1,and experimental group 2 for two personality traits,psychoticism and neuroticism,both inside and outside degree and all four dimensions.CONCLUSION Simple cognitive behavioral therapy could not change the personality characteristics of cancer patients quickly,but the patients’personality characteristics were significantly improved after treatment.
基金supported by the National Natural Science Foundation of China(1140145071171150+4 种基金71471143)the Hubei Provincial Department of Education(B2015348D20141101)the Hubei Province Key Laboratory of Systems Science in Metallurgical Process(Y201518Z201401)
文摘Partial cooperation formulation is a more viable option than optimistic's and pessimistic's to solve an ill-posed bilevel programming problem.Aboussoror's partial cooperation model uses a constant as a cooperation index to describe the degree of follower's cooperation.The constant only indicates the leader's expectation coefficient for the follower's action,not the follower's own willingness.To solve this situation,a new model is proposed by using the follower's satisfactory degree as the cooperation degree.Then,because this new cooperation degree is a function which is dependent on the leader's choice and decided by the follower's satisfactory degree,this paper proves such proposed model not only leads an optimal value between the optimistic value and pessimistic's,but also leads a more satisfactory solution than Aboussoror's.Finally,a numerical experiment is given to demonstrate the feasibility of this new model.
文摘Satisficing control remains an important concept in decision making.In this paper,a new epistemic utility satisficing control theory is proposed for a new model of complex CMMO(constrained multi-objective multi degree-of-freedom optimization)system.As well,an epistemic utility function is developed and used to adjust the feasible region of soft constraints.The theory proved in this paper indicates that the utility function not only expresses the subjectivity of the original satisfactory-degree function,but also takes the cost of searching for a solution into account.Thus,the satisfactory-degree function can be adjusted and its rationality can be validated.This theory contributes an analytical method to the inverse satisfactory optimization problem.The findings indicate that this theory has good convergence and outcomes desired for satisfactory-degree functions.
基金supported by Ecole Nationale Superieure des Arts et Industries Textiles of Francethe National Science Foundation of China(Grant No.60074014)Sichuan Youth Science and Technology Foundation of China
文摘This paper systematically proposes basic requirements on normalization of comprehensive evaluation system with complex uncertain information due to human participation. Four basic academic ideas are as follows: 1) It is necessary to normalize conditions of information acquisition. 2) The effectiveness of comprehensive evaluation depends on the correctness of information acquisition. 3) Any evaluation results can be transformed into linguistic satisfactory degrees. 4) Linguistic values can include a great deal of information. This paper mainly deals with how to select objects to be evaluated, evaluators (panelists) and the methods of information processing, how to construct criteria of evaluation, how to normalize terms of evaluation, the results of evaluation, and the procedure of evaluation.
