The changes of the cytoplasmic free calcium level in the neutrophils after smoke in-halation injury were observed in rabbits and then the effects of tetrandrine,a calcium antago-nist,on the changes of free calcium lev...The changes of the cytoplasmic free calcium level in the neutrophils after smoke in-halation injury were observed in rabbits and then the effects of tetrandrine,a calcium antago-nist,on the changes of free calcium level were studied.It was found that the number of neu-trophils increased significantly preceded by a transient decrease in the blood and also increasedin the bronehoalveolar lavage fluid after smoke inhalation.and the level of cytoplasmic free calci-um in the blood neutrophil increased likewise.Administration of tetrandrine resulted in a reduc-tion of the neutrophils number in the lungs and the free calcium level in the blood neutrophils toalleviate the pulmonary injury due to smoke inhalation.It is believed that there is a close rela-tionship between the activation of neutrophils and the pathophysiological changes of the lungs,and tetrandrine can exert its therapeutic effects on the injury by decreasing the free calcium levelin the neutrophils to modulate their functions.展开更多
三钢6.25 m 3号焦炉采用炭化室压力稳定系统,简称CPS系统,该应用可以实现焦炉无烟装煤以及结焦过程中各炭化室的压力稳定。CPS系统依据装煤、出焦信号,自动完成相应操作,提高了焦炉生产的自动化水平。在投产前期,CPS系统经常出现问题,...三钢6.25 m 3号焦炉采用炭化室压力稳定系统,简称CPS系统,该应用可以实现焦炉无烟装煤以及结焦过程中各炭化室的压力稳定。CPS系统依据装煤、出焦信号,自动完成相应操作,提高了焦炉生产的自动化水平。在投产前期,CPS系统经常出现问题,但通过不断摸索、研究,并针对性地进行改进处理后,相关故障基本上得以消除。展开更多
为提高液熏腊肉风味品质及生产效率,以液熏腊肉为研究对象,改进烟熏液的传统使用方式,探究烟熏液辅助腌制液熏腊肉的加工工艺。以烟熏液体积分数、烟熏液添加量、腌制时间和烘烤时间为单因素影响因子,感官评分为响应值,进行响应面优化分...为提高液熏腊肉风味品质及生产效率,以液熏腊肉为研究对象,改进烟熏液的传统使用方式,探究烟熏液辅助腌制液熏腊肉的加工工艺。以烟熏液体积分数、烟熏液添加量、腌制时间和烘烤时间为单因素影响因子,感官评分为响应值,进行响应面优化分析,与传统湘西腊肉品质进行对比,并采用偏最小二乘判别分析(partial least squares-discriminant analysis,PLS-DA)对液熏腊肉烘烤过程中滋味物质的变化进行综合评价。结果表明:液熏腊肉最佳工艺条件为烟熏液体积分数70%、烟熏液添加量2%(m/m)、腌制时间4d、烘烤时间8d;相比市售湘西腊肉,液熏腊肉具有较高水分含量和亮度值,且食盐和亚硝酸盐含量更低,分别为3.8%和1.20mg/kg;液熏腊肉感官评分为84.56±1.10;通过滋味活度值分析可得,肌苷酸、鸟苷酸(guanosine monophosphate,GMP)、丙氨酸、谷氨酸、赖氨酸、精氨酸、缬氨酸、组氨酸及腺苷酸是液熏腊肉的主要滋味物质;PLS-DA表明,不同烘烤时间下液熏腊肉滋味物质含量存在差异,瓜氨酸、色氨酸、半胱氨酸、次黄嘌呤、GMP、谷氨酰胺、甘氨酸、异亮氨酸及亮氨酸是影响不同烘烤时间液熏腊肉滋味差异的关键指标。展开更多
A rat model was used to explore the therapeutic effects of ginsenosides (GS)on smoke inhalation long injury.It was found that GS could markedly alleviate the in-crease of pulmonary microvascular permeability (PMVP),re...A rat model was used to explore the therapeutic effects of ginsenosides (GS)on smoke inhalation long injury.It was found that GS could markedly alleviate the in-crease of pulmonary microvascular permeability (PMVP),reduction of protein and leu-cocyte content in the bronchoalveolar lavage fluid (BALF) of the smoke inhalation injur-ed rats.Histopathological studies of the lungs revealed that GS could distinctly reduceleucocyte accumulation in the vessels,interstitial infiltration of leucocytes,interstitial andintra-alveolar edema,hemorrhage and vascular congestion.Meanwhile,GS could inhibitthe elevation of malondialdehyde (MDA) in the lungs and serum and reverse the decrea-sed activity of superoxide dismutase (SOD) in the lungs after smoke inhalation.In addi-tion experiments in vitro also showed the inhibition of lipid peroxidation in lung homo-genate and elimination of superoxide anions hydroxyl radicals effectively by GS in properdoses.These results imply that there is close interrelationship between the therapeuticefficiency of GS on smoke inhalation lung injury and its capability of antioxidation.展开更多
文摘The changes of the cytoplasmic free calcium level in the neutrophils after smoke in-halation injury were observed in rabbits and then the effects of tetrandrine,a calcium antago-nist,on the changes of free calcium level were studied.It was found that the number of neu-trophils increased significantly preceded by a transient decrease in the blood and also increasedin the bronehoalveolar lavage fluid after smoke inhalation.and the level of cytoplasmic free calci-um in the blood neutrophil increased likewise.Administration of tetrandrine resulted in a reduc-tion of the neutrophils number in the lungs and the free calcium level in the blood neutrophils toalleviate the pulmonary injury due to smoke inhalation.It is believed that there is a close rela-tionship between the activation of neutrophils and the pathophysiological changes of the lungs,and tetrandrine can exert its therapeutic effects on the injury by decreasing the free calcium levelin the neutrophils to modulate their functions.
文摘三钢6.25 m 3号焦炉采用炭化室压力稳定系统,简称CPS系统,该应用可以实现焦炉无烟装煤以及结焦过程中各炭化室的压力稳定。CPS系统依据装煤、出焦信号,自动完成相应操作,提高了焦炉生产的自动化水平。在投产前期,CPS系统经常出现问题,但通过不断摸索、研究,并针对性地进行改进处理后,相关故障基本上得以消除。
文摘为提高液熏腊肉风味品质及生产效率,以液熏腊肉为研究对象,改进烟熏液的传统使用方式,探究烟熏液辅助腌制液熏腊肉的加工工艺。以烟熏液体积分数、烟熏液添加量、腌制时间和烘烤时间为单因素影响因子,感官评分为响应值,进行响应面优化分析,与传统湘西腊肉品质进行对比,并采用偏最小二乘判别分析(partial least squares-discriminant analysis,PLS-DA)对液熏腊肉烘烤过程中滋味物质的变化进行综合评价。结果表明:液熏腊肉最佳工艺条件为烟熏液体积分数70%、烟熏液添加量2%(m/m)、腌制时间4d、烘烤时间8d;相比市售湘西腊肉,液熏腊肉具有较高水分含量和亮度值,且食盐和亚硝酸盐含量更低,分别为3.8%和1.20mg/kg;液熏腊肉感官评分为84.56±1.10;通过滋味活度值分析可得,肌苷酸、鸟苷酸(guanosine monophosphate,GMP)、丙氨酸、谷氨酸、赖氨酸、精氨酸、缬氨酸、组氨酸及腺苷酸是液熏腊肉的主要滋味物质;PLS-DA表明,不同烘烤时间下液熏腊肉滋味物质含量存在差异,瓜氨酸、色氨酸、半胱氨酸、次黄嘌呤、GMP、谷氨酰胺、甘氨酸、异亮氨酸及亮氨酸是影响不同烘烤时间液熏腊肉滋味差异的关键指标。
文摘A rat model was used to explore the therapeutic effects of ginsenosides (GS)on smoke inhalation long injury.It was found that GS could markedly alleviate the in-crease of pulmonary microvascular permeability (PMVP),reduction of protein and leu-cocyte content in the bronchoalveolar lavage fluid (BALF) of the smoke inhalation injur-ed rats.Histopathological studies of the lungs revealed that GS could distinctly reduceleucocyte accumulation in the vessels,interstitial infiltration of leucocytes,interstitial andintra-alveolar edema,hemorrhage and vascular congestion.Meanwhile,GS could inhibitthe elevation of malondialdehyde (MDA) in the lungs and serum and reverse the decrea-sed activity of superoxide dismutase (SOD) in the lungs after smoke inhalation.In addi-tion experiments in vitro also showed the inhibition of lipid peroxidation in lung homo-genate and elimination of superoxide anions hydroxyl radicals effectively by GS in properdoses.These results imply that there is close interrelationship between the therapeuticefficiency of GS on smoke inhalation lung injury and its capability of antioxidation.
