The effect of expanding swept volume by iNanoW1.0 nanoparticles in ultra-low permeability core was studied by low-field nuclear magnetic resonance(LF-NMR)technology,and the mechanism of expanding swept volume was expl...The effect of expanding swept volume by iNanoW1.0 nanoparticles in ultra-low permeability core was studied by low-field nuclear magnetic resonance(LF-NMR)technology,and the mechanism of expanding swept volume was explained by oxygen spectrum nuclear magnetic resonance(17O-NMR)experiments and capillarity analysis.The results of the LF-NMR experiment show that the nano-sized oil-displacement agent iNanoW1.0 could increase the swept volume by 10%-20%on the basis of conventional water flooding,making water molecules get into the low permeable region with small pores that conventional water flooding could not reach.17O-NMR technique and capillary analysis proved that iNanoW1.0 nanoparticles could weaken the association of hydrogen bonds between water molecules,effectively change the structure of water molecular clusters,and thus increasing the swept volume in the low permeable region.The ability of weakening association of hydrogen bonds between water molecules of iNanoW1.0 nanoparticles increases with its mass fraction and tends to be stable after the mass fraction of 0.1%.展开更多
AIM: To categorize neovessels morphology and to detect response to anti-angiogenic therapy by using structural and angiographic modes of swept source optical coherence tomography(SS-OCT).METHODS: Thirty-two eyes with ...AIM: To categorize neovessels morphology and to detect response to anti-angiogenic therapy by using structural and angiographic modes of swept source optical coherence tomography(SS-OCT).METHODS: Thirty-two eyes with neovessels at disc(NVD) and neovessels elsewhere(NVE)-as diagnosed by fluorescein angiography-were included. Cross sectional OCT images of disc and macular regions were registered to enface OCT angiography(OCTA), B-scan blood flow over lay and density maps. Three eyes received antiangiogenic treatment.RESULTS: Pin point registration of cross-sectional OCT and OCTA images differentiated active NVD with vascular elements from fibrous or equivalent fibrovascular elements. En face images delineated NVE as vascular tufts or area of filling while cross-sectional images differentiated NVE from microvascular intraretinal abnormality(IRMA). All cases were associated with enlargement of foveal avascular zone and or areas of capillary non perfusion. Regressed NVD appeared as ghost vessel or pruned vascular loops after injection.CONCLUSION: Structural and angiographic modes of SS-OCT can detect, characterize and categorize the pattern of wide spectrum of neovessels based on blood flow data and density maps. It is potentially useful to detect ischemic changes in the vascular bed and regression of NVD after therapeutic regimens providing substitute for invasive techniques.展开更多
Commercially available wind-turbines are optimized to operate at certain wind velocity, known as rated wind velocity. For other values of wind velocity, it has different output which is lower than the rated output of ...Commercially available wind-turbines are optimized to operate at certain wind velocity, known as rated wind velocity. For other values of wind velocity, it has different output which is lower than the rated output of the wind plant. Wind mill can be designed to provide maximum power output at different wind velocities through modification of swept area to match with the wind speed available at the moment. This can result in higher power output at all the velocities except that at rated wind speed because of limitation of generator. This results in increased utilization of generation capacity of wind mill compared to its commercially designed counterpart. A theoretical simulation has been done to prove a new concept about swept area of wind turbine blade which results in a significant increase in the power output through the year. Simulation results of power extracted through normal wind blade design and new concept are studied and compared. The findings of the study are presented in graphical and tabular form. Study establishes that there can be a significant gain in the power output with the new concept.展开更多
Crossflow instability plays very important role in the transition ofthe boundary layer on a swept wing, typical in the engineering applications. Experi-ments revealed that the linear stability theory well predicted th...Crossflow instability plays very important role in the transition ofthe boundary layer on a swept wing, typical in the engineering applications. Experi-ments revealed that the linear stability theory well predicted the form of the crossflowvortices, but usually much overpredicted their growth rate. Using nonlinear theoryof hydrodynamic stability, combined with some other considerations, we were able toobtain the growth rate in good agreement with experimental observations.展开更多
Taking reservoir rocks and fluids of the Daqing,Dagang and Changqing oilfields as research objects,the EOR mechanisms and technical approach of polymer flooding were discussed.By comparing the displacement performance...Taking reservoir rocks and fluids of the Daqing,Dagang and Changqing oilfields as research objects,the EOR mechanisms and technical approach of polymer flooding were discussed.By comparing the displacement performances of ordinary polymer,glycerol,polymer in"sheet-net"structure and heterogeneous weak gel at the same viscosity and concentration,the relationship between the viscosity of polymer displacement agents and displacement performance was demonstrated,and the method of improving polymer flooding effect was worked out.The main mechanism of polymer flooding to increase oil recovery is the swept volume expansion of water injection due to polymer retention in porous media.The viscosity of polymer agents has no positive correlation with polymer flooding effect.Although polymer of"sheet-net"structure has strong capacity in increasing viscosity,it has poor compatibility with pore throat structure of reservoir rock,low injectivity and low shear resistance.Heterogeneous weak gel system has higher adsorption and capture capacity in porous media,which is easy to retain in porous media,and can effectively establish seepage resistance in high permeability layers(zones).Compared with polymer solutions with the same viscosity or concentration,it has stronger ability to expand swept volume.Long term injection of polymer flooding agents will inevitably lead to fluid entry profile reversal,and thus worsening of polymer flooding effect.Alternate injection of high retention and low or non-retention displacement agents can further improve the displacement effect of polymer flooding agents.展开更多
Based on practices of CO_(2) flooding tests in China and abroad,the recovery factor of carbon dioxide capture,utilization in displacing oil and storage(CCUS-EOR)in permanent sequestration scenario has been investigate...Based on practices of CO_(2) flooding tests in China and abroad,the recovery factor of carbon dioxide capture,utilization in displacing oil and storage(CCUS-EOR)in permanent sequestration scenario has been investigated in this work.Under the background of carbon neutrality,carbon dioxide injection into geological bodies should pursue the goal of permanent sequestration for effective carbon emission reduction.Hence,CCUS-EOR is an ultimate development method for oil reservoirs to maximize oil recovery.The limit recovery factor of CCUS-EOR development mode is put forward,the connotation differences between it and ultimate recovery factor and economically reasonable recovery factor are clarified.It is concluded that limit recovery factor is achievable with mature supporting technical base for the whole process of CCUS-EOR.Based on statistics of practical data of CO_(2) flooding projects in China and abroad such as North H79 block CO_(2) flooding pilot test at small well spacing in Jilin Oilfield etc.,the empirical relationship between the oil recovery factor of miscible CO_(2) flooding and cumulative CO_(2) volume injected is obtained by regression.Combined with the concept of oil production rate multiplier of gas flooding,a reservoir engineering method calculating CO_(2) flooding recovery factor under any miscible degree is established by derivation.It is found that when the cumulative CO_(2) volume injected is 1.5 times the hydrocarbon pore volume(HCPV),the relative deviation and the absolute difference between the recovery percentage and the limit recovery factor are less than 5%and less than 2.0 percentage points respectively.The limit recovery factor of CCUS-EOR can only be approached by large pore volume(PV)injection based on the technology of expanding swept volume.It needs to be realized from three aspects:large PV injection scheme design,enhancing miscibility degree and continuously expanding swept volume of injected CO_(2).展开更多
AIM: To compare the ocular fundus features of highly myopic eyes with and without macular Bruch’s membrane(BM) defects and investigate the associations between macular BM defects and other myopic lesions.METHODS: Thi...AIM: To compare the ocular fundus features of highly myopic eyes with and without macular Bruch’s membrane(BM) defects and investigate the associations between macular BM defects and other myopic lesions.METHODS: This retrospective, observational case series included 262 eyes(139 patients) with high myopia(HM) refractive error ≥-6.0 diopters(D) or axial length ≥26.5 mm from March 2019 to December 2019.The patients underwent a comprehensive ophthalmic examination, including sweptsource optical coherence tomography(SS-OCT).The features of macular BM defects and other ocular fundus lesions were examined in OCT images.RESULTS: Totally 51 eyes(19.5%) were detected with macular BM defects, which were characterized by a lack of BM, retinal pigment epithelium(RPE), and an almost complete loss of photoreceptors or choriocapillaris.Eyes with macular BM defects had worse best-corrected visual acuity(BCVA) than those without(P<0.001).Dome-shaped macula(DSM, P=0.042), retinal cysts(P=0.006), choroidal neovascularization(CNV, P<0.001), choroidal defects and abnormality(P=0.003), scleral defects(P=0.015), scleral deformation(P=0.005), posterior staphyloma(P=0.011), and perforating vessels(P<0.001) occurred more frequently in eyes with macular BM defects.In multivariate analysis, the presence of macular BM defects remained the significant association with presence of DSM(P=0.013), scleral defects(P=0.015), posterior staphyloma(P=0.001), perforating vessels(P<0.001) and CNV(P=0.004).CONCLUSION: Macular BM defects has a prevalence of approximately 20% in HM and it has tight association with other myopic fundus lesions.BM might be crucial in the pathogenesis of myopic fundus lesions due to its biomechanical function.A comprehensive understanding of BM’s role is useful for further researches about myopic lesions.展开更多
An operational three-dimensional oil spill model is developed by the National Marine Environmental Forecasting Center(NMEFC), State Oceanic Administration, China, and the model has been running for 9 a. On June 4 and ...An operational three-dimensional oil spill model is developed by the National Marine Environmental Forecasting Center(NMEFC), State Oceanic Administration, China, and the model has been running for 9 a. On June 4 and 17,2011, oil is spilled into the sea water from two separate oil platforms in the Bohai Bay, i.e., Platforms B and C of Penglai 19-3 oilfield. The spill causes pollution of thousands of square kilometres of sea area. The NMEFC's oil spill model is employed to study the Penglai 19-3 oil-spill pollution during June to August 2011. The wind final analysis data of the NMEFC, which is based on a weather research and forecasting(WRF) model, are analyzed and corrected by comparing with the observation data. A corrected current filed is obtained by forcing the princeton ocean model(POM) with the corrected wind field. With the above marine environmental field forcing the oil spill model, the oil mass balance and oil distribution can be produced. The simulation is validated against the observation, and it is concluded that the oil spill model of the NMEFC is able to commendably simulate the oil spill distribution. Thus the NMEFC's oil spill model can provide a tool in an environmental impact assessment after the event.展开更多
While roundabouts have already been proven to be an effective intersection treatment, there are many instances where low-clearance vehicles have problems using roundabouts. Low-clearance vehicles, such as lowboy trail...While roundabouts have already been proven to be an effective intersection treatment, there are many instances where low-clearance vehicles have problems using roundabouts. Low-clearance vehicles, such as lowboy trailer trucks, have problems, damaging the curbs and truck aprons at roundabouts when there is not sufficient ground clearance. This area has been generally neglected by designers and U.S. states. The latest roundabout manual has guidelines available to design various features of the roundabouts, but they are not specific for low-clearance vehicles. While some previous studies have identified roundabout locations with ground-clearance problems for lowboy trailers that have truck-apron heights that are greater than three inches, no published information is available about truck-apron heights based on three-dimensional analyses. This study addresses the ground-clearance problems for low-clearance vehicles at roundabouts by proposing a procedure where truck-apron heights, truck-apron slope, circulatory roadway slope, and approach roadway slope are analyzed to determine the optimum design measurements for a roundabout’s vertical profile in order to accommodate low-clearance vehicles without terrain conflict. The study procedure was demonstrated on standard single-lane roundabouts and double-lane roundabouts designed according to latest roundabout guide, and recommendations were provided for truck-apron heights and the grade for various features of the roundabouts. This research can guide transportation planners and decision makers when determining the optimum roundabout vertical-profile design when low-clearance vehicles are expected. The study uses TORUS software to design roundabouts, and the AUTOTURN and AUTOTURN Pro 3D software for generating two-dimensional and three-dimensional vehicle simulations as well as for conducting three-dimensional vehicle-clearance analysis.展开更多
Experiments on surface-active polymer flooding for enhanced oil recovery were carried out by detection analysis and modern physical simulation technique based on reservoirs and fluids in Daqing placanticline oilfield....Experiments on surface-active polymer flooding for enhanced oil recovery were carried out by detection analysis and modern physical simulation technique based on reservoirs and fluids in Daqing placanticline oilfield.The experimental results show that the surface-active polymer is different from other common polymers and polymer-surfactant systems in molecular aggregation,viscosity and flow capacity,and it has larger molecular coil size,higher viscosity and viscosifying capacity,and poorer mobility.The surface-active polymer solution has good performance of viscosity-increasing and viscosity retention,and has good performance of viscoelasticity and deformability to exert positive effects of viscosifying and viscoelastic properties.Surface-active polymer can change the chemical property of interface and reduce interfacial tension,making the reservoir rock turn water-wet,also it can emulsify the oil into relatively stable oil-in-water emulsion,and emulsification capacity is an important property to enhance oil washing efficiency under non-ultralow interfacial tension.The surface-active polymer flooding enlarges swept volume in two ways:Microscopically,the surface-active polymer has mobility control effect and can enter oil-bearing pores not swept by water to drive residual oil,and its mobility control effect has more contribution than oil washing capacity in enhancing oil recovery.Macroscopically,it has plugging capacity,and can emulsify and plug the dominant channels in layers with high permeability,forcing the injected fluid to enter the layer with medium or low permeability and low flow resistance,and thus enlarging swept volume.展开更多
Background:To measure the anterior and posterior segment structural features of acute primary angle-closure(APAC)eyes.Methods:A total of 36 subjects with unilateral APAC were recruited in this study.The ocular biometr...Background:To measure the anterior and posterior segment structural features of acute primary angle-closure(APAC)eyes.Methods:A total of 36 subjects with unilateral APAC were recruited in this study.The ocular biometric characteristics were measured by anterior segment optical coherence tomography(AS-OCT)and swept source optical coherence tomography(SS-OCT),respectively at baseline,2 weeks,and 1 month after surgical intervention.Results:At baseline,when compared with the fellow eyes,APAC-affected eyes showed significantly greater corneal thickness(P=0.004),shallower anterior chamber depth(ACD)(P<0.001),smaller anterior chamber area(ACA)(P=0.013),angle opening distance at 750μm from the scleral spur(AOD750)(P=0.002),trabecular-iris space area at 750μm from the scleral spur(TISA750)(P=0.033),angle recess area(ARA)(P=0.014),and iris area(IARE)(P=0.003),less iris curvature(ICURVE)(P=0.003),and larger lens vault(LV)(P=0.030).After intervention,the corneal thickness was significantly decreased at 1 month(P<0.001),while ACD,ACA,and AOD750 were significantly increased at 2 weeks and 1 month(all P<0.017).Changes in ACD were correlated with decreasing LV(P<0.05).The posterior segment parameters did not change over the 4-week period.Conclusions:When compared with the fellow eyes,APAC-affected eyes had greater corneal thickness,shallower anterior chamber,narrower angle,less ICURVE,and larger LV.After intervention,the corneal thickness was decreased,while the shallower anterior chamber was relieved to some extent.展开更多
Machine learning has been widely utilized in flow field modeling and aerodynamic optimization.However,most applications are limited to two-dimensional problems.The dimensionality and the cost per simulation of three-d...Machine learning has been widely utilized in flow field modeling and aerodynamic optimization.However,most applications are limited to two-dimensional problems.The dimensionality and the cost per simulation of three-dimensional problems are so high that it is often too expensive to prepare sufficient samples.Therefore,transfer learning has become a promising approach to reuse well-trained two-dimensional models and greatly reduce the need for samples for threedimensional problems.This paper proposes to reuse the baseline models trained on supercritical airfoils to predict finite-span swept supercritical wings,where the simple swept theory is embedded to improve the prediction accuracy.Two baseline models are investigated:one is commonly referred to as the forward problem of predicting the pressure coefficient distribution based on the geometry,and the other is the inverse problem that predicts the geometry based on the pressure coefficient distribution.Two transfer learning strategies are compared for both baseline models.The transferred models are then tested on complete wings.The results show that transfer learning requires only approximately 500 wing samples to achieve good prediction accuracy on different wing planforms and different free stream conditions.Compared to the two baseline models,the transferred models reduce the prediction error by 60%and 80%,respectively.展开更多
Swept source optical coherence tomography(SS-OCT)is a new noninvasive technique for assessing tissue.Although it hasadvantages,such as being label-free,noninvasive,and with high resolution,it also has drawbacks:there ...Swept source optical coherence tomography(SS-OCT)is a new noninvasive technique for assessing tissue.Although it hasadvantages,such as being label-free,noninvasive,and with high resolution,it also has drawbacks:there has been no indepth research into identifying the driving of swept source.Based on preliminary research,we demonstrate a novel drivingmodulation method of a fiber Fabry–Perot tunable filter ranging phase adjustable as a tool for making bandwidth compensation of a swept laser source.This novel method is analyzed in detail;a swept laser source with a sweep rate of100.5 kHz over a range of 152.25 nm and at a center wavelength of 1335.45 nm is demonstrated.展开更多
Scallop ice is a special phenomenon that occurs during swept wing aircraft passing through icing clouds.It poses a great challenge for the icing safety assessment that the complex scallop ice shape feature and its mec...Scallop ice is a special phenomenon that occurs during swept wing aircraft passing through icing clouds.It poses a great challenge for the icing safety assessment that the complex scallop ice shape feature and its mechanism are still unclear.In this work,a large-scale icing wind tunnel experiment of swept wing designed by NACA0012 airfoil is conducted in the Icing Wind Tunnel of China Aerodynamics Research and Development Center.The detailed three-dimensional ice shapes under 0°,15°,30°and 45°swept angles are obtained by laser scanning technology.The experimental results show that with the swept angle increasing from 0°to 45°,the 2D double ice horn structures show certain spanwise variation,and finally transform into complete scallop ice with ice thickness greatly enhanced in the stagnation line region.The empirical mode decomposition of the spanwise ice curve captures the high-frequency fluctuation on the scallop ice caused by the small-scale roughness element,while the trend with low frequency is not obvious.Based on the experimental data,a new complete scallop ice geometric model,named 5Points-5Lines-2Arcs(5P-5L-2A)model,is proposed,which can provide important basis for the quantitative description of complex scallop ice shape.展开更多
基金Supported by the PetroChina Scientifc Research and Technological Development Project(2018A-0907).
文摘The effect of expanding swept volume by iNanoW1.0 nanoparticles in ultra-low permeability core was studied by low-field nuclear magnetic resonance(LF-NMR)technology,and the mechanism of expanding swept volume was explained by oxygen spectrum nuclear magnetic resonance(17O-NMR)experiments and capillarity analysis.The results of the LF-NMR experiment show that the nano-sized oil-displacement agent iNanoW1.0 could increase the swept volume by 10%-20%on the basis of conventional water flooding,making water molecules get into the low permeable region with small pores that conventional water flooding could not reach.17O-NMR technique and capillary analysis proved that iNanoW1.0 nanoparticles could weaken the association of hydrogen bonds between water molecules,effectively change the structure of water molecular clusters,and thus increasing the swept volume in the low permeable region.The ability of weakening association of hydrogen bonds between water molecules of iNanoW1.0 nanoparticles increases with its mass fraction and tends to be stable after the mass fraction of 0.1%.
文摘AIM: To categorize neovessels morphology and to detect response to anti-angiogenic therapy by using structural and angiographic modes of swept source optical coherence tomography(SS-OCT).METHODS: Thirty-two eyes with neovessels at disc(NVD) and neovessels elsewhere(NVE)-as diagnosed by fluorescein angiography-were included. Cross sectional OCT images of disc and macular regions were registered to enface OCT angiography(OCTA), B-scan blood flow over lay and density maps. Three eyes received antiangiogenic treatment.RESULTS: Pin point registration of cross-sectional OCT and OCTA images differentiated active NVD with vascular elements from fibrous or equivalent fibrovascular elements. En face images delineated NVE as vascular tufts or area of filling while cross-sectional images differentiated NVE from microvascular intraretinal abnormality(IRMA). All cases were associated with enlargement of foveal avascular zone and or areas of capillary non perfusion. Regressed NVD appeared as ghost vessel or pruned vascular loops after injection.CONCLUSION: Structural and angiographic modes of SS-OCT can detect, characterize and categorize the pattern of wide spectrum of neovessels based on blood flow data and density maps. It is potentially useful to detect ischemic changes in the vascular bed and regression of NVD after therapeutic regimens providing substitute for invasive techniques.
文摘Commercially available wind-turbines are optimized to operate at certain wind velocity, known as rated wind velocity. For other values of wind velocity, it has different output which is lower than the rated output of the wind plant. Wind mill can be designed to provide maximum power output at different wind velocities through modification of swept area to match with the wind speed available at the moment. This can result in higher power output at all the velocities except that at rated wind speed because of limitation of generator. This results in increased utilization of generation capacity of wind mill compared to its commercially designed counterpart. A theoretical simulation has been done to prove a new concept about swept area of wind turbine blade which results in a significant increase in the power output through the year. Simulation results of power extracted through normal wind blade design and new concept are studied and compared. The findings of the study are presented in graphical and tabular form. Study establishes that there can be a significant gain in the power output with the new concept.
基金The project supported by the National Natural Science Foundation of China, Grant No.19572048
文摘Crossflow instability plays very important role in the transition ofthe boundary layer on a swept wing, typical in the engineering applications. Experi-ments revealed that the linear stability theory well predicted the form of the crossflowvortices, but usually much overpredicted their growth rate. Using nonlinear theoryof hydrodynamic stability, combined with some other considerations, we were able toobtain the growth rate in good agreement with experimental observations.
基金Supported by the National Major Special Project of Oil and Gas During the 13th Five-Year Plan Period(NO.2016ZX05058-003-010)General Program of National Natural Science Foundation of China(NO.51574086)Postdoctoral Innovative Talent Support Program of China(NO.BX20190065)。
文摘Taking reservoir rocks and fluids of the Daqing,Dagang and Changqing oilfields as research objects,the EOR mechanisms and technical approach of polymer flooding were discussed.By comparing the displacement performances of ordinary polymer,glycerol,polymer in"sheet-net"structure and heterogeneous weak gel at the same viscosity and concentration,the relationship between the viscosity of polymer displacement agents and displacement performance was demonstrated,and the method of improving polymer flooding effect was worked out.The main mechanism of polymer flooding to increase oil recovery is the swept volume expansion of water injection due to polymer retention in porous media.The viscosity of polymer agents has no positive correlation with polymer flooding effect.Although polymer of"sheet-net"structure has strong capacity in increasing viscosity,it has poor compatibility with pore throat structure of reservoir rock,low injectivity and low shear resistance.Heterogeneous weak gel system has higher adsorption and capture capacity in porous media,which is easy to retain in porous media,and can effectively establish seepage resistance in high permeability layers(zones).Compared with polymer solutions with the same viscosity or concentration,it has stronger ability to expand swept volume.Long term injection of polymer flooding agents will inevitably lead to fluid entry profile reversal,and thus worsening of polymer flooding effect.Alternate injection of high retention and low or non-retention displacement agents can further improve the displacement effect of polymer flooding agents.
基金Supported by CNPC Science and Technology Project(kt2022-8-202021ZZ01).
文摘Based on practices of CO_(2) flooding tests in China and abroad,the recovery factor of carbon dioxide capture,utilization in displacing oil and storage(CCUS-EOR)in permanent sequestration scenario has been investigated in this work.Under the background of carbon neutrality,carbon dioxide injection into geological bodies should pursue the goal of permanent sequestration for effective carbon emission reduction.Hence,CCUS-EOR is an ultimate development method for oil reservoirs to maximize oil recovery.The limit recovery factor of CCUS-EOR development mode is put forward,the connotation differences between it and ultimate recovery factor and economically reasonable recovery factor are clarified.It is concluded that limit recovery factor is achievable with mature supporting technical base for the whole process of CCUS-EOR.Based on statistics of practical data of CO_(2) flooding projects in China and abroad such as North H79 block CO_(2) flooding pilot test at small well spacing in Jilin Oilfield etc.,the empirical relationship between the oil recovery factor of miscible CO_(2) flooding and cumulative CO_(2) volume injected is obtained by regression.Combined with the concept of oil production rate multiplier of gas flooding,a reservoir engineering method calculating CO_(2) flooding recovery factor under any miscible degree is established by derivation.It is found that when the cumulative CO_(2) volume injected is 1.5 times the hydrocarbon pore volume(HCPV),the relative deviation and the absolute difference between the recovery percentage and the limit recovery factor are less than 5%and less than 2.0 percentage points respectively.The limit recovery factor of CCUS-EOR can only be approached by large pore volume(PV)injection based on the technology of expanding swept volume.It needs to be realized from three aspects:large PV injection scheme design,enhancing miscibility degree and continuously expanding swept volume of injected CO_(2).
文摘AIM: To compare the ocular fundus features of highly myopic eyes with and without macular Bruch’s membrane(BM) defects and investigate the associations between macular BM defects and other myopic lesions.METHODS: This retrospective, observational case series included 262 eyes(139 patients) with high myopia(HM) refractive error ≥-6.0 diopters(D) or axial length ≥26.5 mm from March 2019 to December 2019.The patients underwent a comprehensive ophthalmic examination, including sweptsource optical coherence tomography(SS-OCT).The features of macular BM defects and other ocular fundus lesions were examined in OCT images.RESULTS: Totally 51 eyes(19.5%) were detected with macular BM defects, which were characterized by a lack of BM, retinal pigment epithelium(RPE), and an almost complete loss of photoreceptors or choriocapillaris.Eyes with macular BM defects had worse best-corrected visual acuity(BCVA) than those without(P<0.001).Dome-shaped macula(DSM, P=0.042), retinal cysts(P=0.006), choroidal neovascularization(CNV, P<0.001), choroidal defects and abnormality(P=0.003), scleral defects(P=0.015), scleral deformation(P=0.005), posterior staphyloma(P=0.011), and perforating vessels(P<0.001) occurred more frequently in eyes with macular BM defects.In multivariate analysis, the presence of macular BM defects remained the significant association with presence of DSM(P=0.013), scleral defects(P=0.015), posterior staphyloma(P=0.001), perforating vessels(P<0.001) and CNV(P=0.004).CONCLUSION: Macular BM defects has a prevalence of approximately 20% in HM and it has tight association with other myopic fundus lesions.BM might be crucial in the pathogenesis of myopic fundus lesions due to its biomechanical function.A comprehensive understanding of BM’s role is useful for further researches about myopic lesions.
基金The Open Project Fund of the Key Laboratory of Shangdong Province for Marine Ecological Environment and Disaster Prevention and Mitigation of China under contract No.201402the Project of the Key Laboratory of Marine Spill Oil Identification and Damage Assessment Technology,State Oceanic Administration of China under contract No.201604+1 种基金the National Marine Public Welfare Research Project of China under contract No.201305031the Cooperation on the Development of Basic Technologies for the Yellow Sea and East China Sea Operational Oceanographic System funded by the China-Korea Joint Ocean Research and the National Natural Science Foundation of China under contract Nos 41206106 and 41406042
文摘An operational three-dimensional oil spill model is developed by the National Marine Environmental Forecasting Center(NMEFC), State Oceanic Administration, China, and the model has been running for 9 a. On June 4 and 17,2011, oil is spilled into the sea water from two separate oil platforms in the Bohai Bay, i.e., Platforms B and C of Penglai 19-3 oilfield. The spill causes pollution of thousands of square kilometres of sea area. The NMEFC's oil spill model is employed to study the Penglai 19-3 oil-spill pollution during June to August 2011. The wind final analysis data of the NMEFC, which is based on a weather research and forecasting(WRF) model, are analyzed and corrected by comparing with the observation data. A corrected current filed is obtained by forcing the princeton ocean model(POM) with the corrected wind field. With the above marine environmental field forcing the oil spill model, the oil mass balance and oil distribution can be produced. The simulation is validated against the observation, and it is concluded that the oil spill model of the NMEFC is able to commendably simulate the oil spill distribution. Thus the NMEFC's oil spill model can provide a tool in an environmental impact assessment after the event.
文摘While roundabouts have already been proven to be an effective intersection treatment, there are many instances where low-clearance vehicles have problems using roundabouts. Low-clearance vehicles, such as lowboy trailer trucks, have problems, damaging the curbs and truck aprons at roundabouts when there is not sufficient ground clearance. This area has been generally neglected by designers and U.S. states. The latest roundabout manual has guidelines available to design various features of the roundabouts, but they are not specific for low-clearance vehicles. While some previous studies have identified roundabout locations with ground-clearance problems for lowboy trailers that have truck-apron heights that are greater than three inches, no published information is available about truck-apron heights based on three-dimensional analyses. This study addresses the ground-clearance problems for low-clearance vehicles at roundabouts by proposing a procedure where truck-apron heights, truck-apron slope, circulatory roadway slope, and approach roadway slope are analyzed to determine the optimum design measurements for a roundabout’s vertical profile in order to accommodate low-clearance vehicles without terrain conflict. The study procedure was demonstrated on standard single-lane roundabouts and double-lane roundabouts designed according to latest roundabout guide, and recommendations were provided for truck-apron heights and the grade for various features of the roundabouts. This research can guide transportation planners and decision makers when determining the optimum roundabout vertical-profile design when low-clearance vehicles are expected. The study uses TORUS software to design roundabouts, and the AUTOTURN and AUTOTURN Pro 3D software for generating two-dimensional and three-dimensional vehicle simulations as well as for conducting three-dimensional vehicle-clearance analysis.
基金Supported by China National Science and Technology Major Project(2016ZX05010002-004 and 2016ZX05023005-001-003)China Postdoctoral Science Foundation(2019M651255)National Natural Science Foundation of China(51804078).
文摘Experiments on surface-active polymer flooding for enhanced oil recovery were carried out by detection analysis and modern physical simulation technique based on reservoirs and fluids in Daqing placanticline oilfield.The experimental results show that the surface-active polymer is different from other common polymers and polymer-surfactant systems in molecular aggregation,viscosity and flow capacity,and it has larger molecular coil size,higher viscosity and viscosifying capacity,and poorer mobility.The surface-active polymer solution has good performance of viscosity-increasing and viscosity retention,and has good performance of viscoelasticity and deformability to exert positive effects of viscosifying and viscoelastic properties.Surface-active polymer can change the chemical property of interface and reduce interfacial tension,making the reservoir rock turn water-wet,also it can emulsify the oil into relatively stable oil-in-water emulsion,and emulsification capacity is an important property to enhance oil washing efficiency under non-ultralow interfacial tension.The surface-active polymer flooding enlarges swept volume in two ways:Microscopically,the surface-active polymer has mobility control effect and can enter oil-bearing pores not swept by water to drive residual oil,and its mobility control effect has more contribution than oil washing capacity in enhancing oil recovery.Macroscopically,it has plugging capacity,and can emulsify and plug the dominant channels in layers with high permeability,forcing the injected fluid to enter the layer with medium or low permeability and low flow resistance,and thus enlarging swept volume.
基金The study was funded by Science and Technology Program of Guangzhou,China(201803010066)the National Natural Science Foundation of China(82000890)Young Talents’Science and Technology Innovation Project of Hainan Association for Science and Technology(QCXM202020).
文摘Background:To measure the anterior and posterior segment structural features of acute primary angle-closure(APAC)eyes.Methods:A total of 36 subjects with unilateral APAC were recruited in this study.The ocular biometric characteristics were measured by anterior segment optical coherence tomography(AS-OCT)and swept source optical coherence tomography(SS-OCT),respectively at baseline,2 weeks,and 1 month after surgical intervention.Results:At baseline,when compared with the fellow eyes,APAC-affected eyes showed significantly greater corneal thickness(P=0.004),shallower anterior chamber depth(ACD)(P<0.001),smaller anterior chamber area(ACA)(P=0.013),angle opening distance at 750μm from the scleral spur(AOD750)(P=0.002),trabecular-iris space area at 750μm from the scleral spur(TISA750)(P=0.033),angle recess area(ARA)(P=0.014),and iris area(IARE)(P=0.003),less iris curvature(ICURVE)(P=0.003),and larger lens vault(LV)(P=0.030).After intervention,the corneal thickness was significantly decreased at 1 month(P<0.001),while ACD,ACA,and AOD750 were significantly increased at 2 weeks and 1 month(all P<0.017).Changes in ACD were correlated with decreasing LV(P<0.05).The posterior segment parameters did not change over the 4-week period.Conclusions:When compared with the fellow eyes,APAC-affected eyes had greater corneal thickness,shallower anterior chamber,narrower angle,less ICURVE,and larger LV.After intervention,the corneal thickness was decreased,while the shallower anterior chamber was relieved to some extent.
基金supported by the National Natural Science Foundation of China(Nos.92052203,12202243 and 11872230).
文摘Machine learning has been widely utilized in flow field modeling and aerodynamic optimization.However,most applications are limited to two-dimensional problems.The dimensionality and the cost per simulation of three-dimensional problems are so high that it is often too expensive to prepare sufficient samples.Therefore,transfer learning has become a promising approach to reuse well-trained two-dimensional models and greatly reduce the need for samples for threedimensional problems.This paper proposes to reuse the baseline models trained on supercritical airfoils to predict finite-span swept supercritical wings,where the simple swept theory is embedded to improve the prediction accuracy.Two baseline models are investigated:one is commonly referred to as the forward problem of predicting the pressure coefficient distribution based on the geometry,and the other is the inverse problem that predicts the geometry based on the pressure coefficient distribution.Two transfer learning strategies are compared for both baseline models.The transferred models are then tested on complete wings.The results show that transfer learning requires only approximately 500 wing samples to achieve good prediction accuracy on different wing planforms and different free stream conditions.Compared to the two baseline models,the transferred models reduce the prediction error by 60%and 80%,respectively.
基金supported in part by the Shenzhen Key Project for Technology Development(Nos.JSGG2020110215360002,JSGG20191129105838333,and CJGJZD20200617103003009).
文摘Swept source optical coherence tomography(SS-OCT)is a new noninvasive technique for assessing tissue.Although it hasadvantages,such as being label-free,noninvasive,and with high resolution,it also has drawbacks:there has been no indepth research into identifying the driving of swept source.Based on preliminary research,we demonstrate a novel drivingmodulation method of a fiber Fabry–Perot tunable filter ranging phase adjustable as a tool for making bandwidth compensation of a swept laser source.This novel method is analyzed in detail;a swept laser source with a sweep rate of100.5 kHz over a range of 152.25 nm and at a center wavelength of 1335.45 nm is demonstrated.
基金co-supported by the National Natural Science Foundation of China (Nos. 12172372 and 12132019)the National Major Science and Technology Projects of China (No. J2019-III-0010-0054)
文摘Scallop ice is a special phenomenon that occurs during swept wing aircraft passing through icing clouds.It poses a great challenge for the icing safety assessment that the complex scallop ice shape feature and its mechanism are still unclear.In this work,a large-scale icing wind tunnel experiment of swept wing designed by NACA0012 airfoil is conducted in the Icing Wind Tunnel of China Aerodynamics Research and Development Center.The detailed three-dimensional ice shapes under 0°,15°,30°and 45°swept angles are obtained by laser scanning technology.The experimental results show that with the swept angle increasing from 0°to 45°,the 2D double ice horn structures show certain spanwise variation,and finally transform into complete scallop ice with ice thickness greatly enhanced in the stagnation line region.The empirical mode decomposition of the spanwise ice curve captures the high-frequency fluctuation on the scallop ice caused by the small-scale roughness element,while the trend with low frequency is not obvious.Based on the experimental data,a new complete scallop ice geometric model,named 5Points-5Lines-2Arcs(5P-5L-2A)model,is proposed,which can provide important basis for the quantitative description of complex scallop ice shape.
