Alzheimer’s disease（AD）is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregat...Alzheimer’s disease（AD）is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregated amyloid beta（Aβ）,and neurofibrillary tangles composed of the hyperphosphorylated form of the microtubule protein tau.It is the most common form of dementia which is characterized by severe neurodegenerative changes such as loss of neurons and synapses in brain（Kamat et al.,2014）.展开更多
Transmission through seemingly opaque surfaces,so-called extraordinary transmission,provides an exciting platform for strong light–matter interaction,spectroscopy,optical trapping,and color filtering.Much of the effo...Transmission through seemingly opaque surfaces,so-called extraordinary transmission,provides an exciting platform for strong light–matter interaction,spectroscopy,optical trapping,and color filtering.Much of the effort has been devoted to understanding and exploiting TM extraordinary transmission,while TE anomalous extraordinary transmission has been largely omitted in the literature.This is regrettable from a practical point of view since the stronger dependence of the TE anomalous extraordinary transmission on the array’s substrate provides additional design parameters for exploitation.To provide high-performance and cost-effective applications based on TE anomalous extraordinary transmission,a complete physical insight about the underlying mechanisms of the phenomenon must be first laid down.To this end,resorting to a combined methodology including quasi-optical terahertz(THz)time-domain measurements,full-wave simulations,and method of moments analysis,subwavelength slit arrays under s-polarized illumination are studied here,filling the void in the current literature.We believe this work unequivocally reveals the leaky-wave role of the grounded-dielectric slab mode mediating in TE anomalous extraordinary transmission and provides the necessary framework to design practical high-performance THz components and systems.展开更多
Evaporation （E） rate and precipitation （P） rate are two significant meteorological elements required in the ocean baro- clinic modeling as external forcings. However, there are some uncertainties in the currently ...Evaporation （E） rate and precipitation （P） rate are two significant meteorological elements required in the ocean baro- clinic modeling as external forcings. However, there are some uncertainties in the currently used E/P rates datasets, especially in terms of the data quality. In this study, we collected E/P rates data from ERA-40, NCEP/NCAR Reanalysis, HOAPS for the Bohai Sea and nine routine stations around Laizhou Bay, and made comparisons among them. It was found that the differences in E/P rates between land and sea are remarkable, which was due to the difference in underlying surfaces. Therefore, the traditional way of using E/P rates acquired on land directly at sea is not correct. Since no final conclusion has been reached concerning the net water transport between the Bohai Sea and the Yellow Sea, it is unfeasible to judge the adequacy of the four kinds of data by using the water budget equation. However, the E/P rates at ERA-40 sea points were considered to he the optimal in terms of temporal/spatial coverage and resolution for the hindcast of salinity variation in the Bohai Sea. Besides, using the 3-D hydrodynamic model HAMSOM （HAMburg Shelf Ocean Model）, we performed numerical experiments with different E/P datasets and found that the E/P rates at sea points from ERA-40 dataset are better than those from NCEP/NCAR Reanalysis dataset. If NCEP/NCAR Reanalysis E/P rates are to be used, they need to be adjusted and tested prior to simulation so that more close-to-reality salinity values can be reproduced.展开更多
Based on one year gradient wind data and the wind data of a strong typhoon observed by three meteorological towers located on the coast and at the inshore sea,the underlying surfaces of the meteorological towers were ...Based on one year gradient wind data and the wind data of a strong typhoon observed by three meteorological towers located on the coast and at the inshore sea,the underlying surfaces of the meteorological towers were classified and the roughness lengths were calculated quantitatively.On the basis of strong wind characteristic representative assessment and sample selection on the wind data of strong typhoon Hagupit,the gust factor variation characteristics of tropical cyclones under different underlying surfaces were analyzed.The observed fact and variation rule were found as follows:1) The roughness lengths under neutral atmospheric condition which were calculated using logarithmic wind profile fitting based on the observation data can describe the slight change of the underlying surface objectively.2) The gust factor of strong typhoon wind didn't have variation trends with wind speed.But the variation amplitude of the gust factor was rather large over rough underlying surface which had pronounced effect on the numerical design of structural engineering.3) The variation of the gust factor with height satisfied power law or logarithmic law.The power law fitting was more suitable for smooth underlying surface while the logarithmic fitting was better over rough underlying surface.4) The observation data also suggested that the relationship between gust factor and roughness length can be described by power or linear equation.5) The gust factor observed in this typhoon case was different from the gust factor recommended by WMO:The gust factor of the offshore wind came from rough underlying surface was higher than the value recommended by WMO while the gust factor of the onshore wind came from smooth underlying surface is less than the WMO recommended value.展开更多
基金supported in part by the Council of Scientific and Industrial Research (CSIR), Indiafinancial support to Pradip Kumar Kamat
文摘Alzheimer’s disease（AD）is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregated amyloid beta（Aβ）,and neurofibrillary tangles composed of the hyperphosphorylated form of the microtubule protein tau.It is the most common form of dementia which is characterized by severe neurodegenerative changes such as loss of neurons and synapses in brain（Kamat et al.,2014）.
基金Engineering and Physical Sciences Research Council(EP/L015331/1,EP/S018395/1,2137478)Russian Foundation for Basic Research(18-29-20066)+3 种基金Ministerio de Ciencia,Innovación y Universidades(RTI2018-094475-B-I00)Royal Society(RSG/R1/180040)University of Birmingham(Birmingham Fellowship)Ministerio de Ciencia,Innovación y Universidades(TEC2017-84724-P)。
文摘Transmission through seemingly opaque surfaces,so-called extraordinary transmission,provides an exciting platform for strong light–matter interaction,spectroscopy,optical trapping,and color filtering.Much of the effort has been devoted to understanding and exploiting TM extraordinary transmission,while TE anomalous extraordinary transmission has been largely omitted in the literature.This is regrettable from a practical point of view since the stronger dependence of the TE anomalous extraordinary transmission on the array’s substrate provides additional design parameters for exploitation.To provide high-performance and cost-effective applications based on TE anomalous extraordinary transmission,a complete physical insight about the underlying mechanisms of the phenomenon must be first laid down.To this end,resorting to a combined methodology including quasi-optical terahertz(THz)time-domain measurements,full-wave simulations,and method of moments analysis,subwavelength slit arrays under s-polarized illumination are studied here,filling the void in the current literature.We believe this work unequivocally reveals the leaky-wave role of the grounded-dielectric slab mode mediating in TE anomalous extraordinary transmission and provides the necessary framework to design practical high-performance THz components and systems.
基金sponsored by the National Key Basic Research Science Foundation (973 project) "Marine Physical Variations in Eastern Marginal Seas of China and Their Environmental Impacts" (2005CB422303)the Program for New Century Excellent Talents in Universities (NCET-05-0592)
文摘Evaporation （E） rate and precipitation （P） rate are two significant meteorological elements required in the ocean baro- clinic modeling as external forcings. However, there are some uncertainties in the currently used E/P rates datasets, especially in terms of the data quality. In this study, we collected E/P rates data from ERA-40, NCEP/NCAR Reanalysis, HOAPS for the Bohai Sea and nine routine stations around Laizhou Bay, and made comparisons among them. It was found that the differences in E/P rates between land and sea are remarkable, which was due to the difference in underlying surfaces. Therefore, the traditional way of using E/P rates acquired on land directly at sea is not correct. Since no final conclusion has been reached concerning the net water transport between the Bohai Sea and the Yellow Sea, it is unfeasible to judge the adequacy of the four kinds of data by using the water budget equation. However, the E/P rates at ERA-40 sea points were considered to he the optimal in terms of temporal/spatial coverage and resolution for the hindcast of salinity variation in the Bohai Sea. Besides, using the 3-D hydrodynamic model HAMSOM （HAMburg Shelf Ocean Model）, we performed numerical experiments with different E/P datasets and found that the E/P rates at sea points from ERA-40 dataset are better than those from NCEP/NCAR Reanalysis dataset. If NCEP/NCAR Reanalysis E/P rates are to be used, they need to be adjusted and tested prior to simulation so that more close-to-reality salinity values can be reproduced.
基金supported by the National Natural Science Foundation of China (Grant Nos. 90715031, 40775071) the National Special Re-search Fund for Non-Profit Sector of China Ministry of Science and Tech-nology (Grant No. GYHY200806012)
文摘Based on one year gradient wind data and the wind data of a strong typhoon observed by three meteorological towers located on the coast and at the inshore sea,the underlying surfaces of the meteorological towers were classified and the roughness lengths were calculated quantitatively.On the basis of strong wind characteristic representative assessment and sample selection on the wind data of strong typhoon Hagupit,the gust factor variation characteristics of tropical cyclones under different underlying surfaces were analyzed.The observed fact and variation rule were found as follows:1) The roughness lengths under neutral atmospheric condition which were calculated using logarithmic wind profile fitting based on the observation data can describe the slight change of the underlying surface objectively.2) The gust factor of strong typhoon wind didn't have variation trends with wind speed.But the variation amplitude of the gust factor was rather large over rough underlying surface which had pronounced effect on the numerical design of structural engineering.3) The variation of the gust factor with height satisfied power law or logarithmic law.The power law fitting was more suitable for smooth underlying surface while the logarithmic fitting was better over rough underlying surface.4) The observation data also suggested that the relationship between gust factor and roughness length can be described by power or linear equation.5) The gust factor observed in this typhoon case was different from the gust factor recommended by WMO:The gust factor of the offshore wind came from rough underlying surface was higher than the value recommended by WMO while the gust factor of the onshore wind came from smooth underlying surface is less than the WMO recommended value.
