With the development of anti-virus technology,malicious documents have gradually become the main pathway of Advanced Persistent Threat(APT)attacks,therefore,the development of effective malicious document classifiers ...With the development of anti-virus technology,malicious documents have gradually become the main pathway of Advanced Persistent Threat(APT)attacks,therefore,the development of effective malicious document classifiers has become particularly urgent.Currently,detection methods based on document structure and behavioral features encounter challenges in feature engineering,these methods not only have limited accuracy,but also consume large resources,and usually can only detect documents in specific formats,which lacks versatility and adaptability.To address such problems,this paper proposes a novel malicious document detection method-visualizing documents as GGE images(Grayscale,Grayscale matrix,Entropy).The GGE method visualizes the original byte sequence of the malicious document as a grayscale image,the information entropy sequence of the document as an entropy image,and at the same time,the grayscale level co-occurrence matrix and the texture and spatial information stored in it are converted into grayscale matrix image,and fuses the three types of images to get the GGE color image.The Convolutional Block Attention Module-EfficientNet-B0(CBAM-EfficientNet-B0)model is then used for classification,combining transfer learning and applying the pre-trained model on the ImageNet dataset to the feature extraction process of GGE images.As shown in the experimental results,the GGE method has superior performance compared with other methods,which is suitable for detecting malicious documents in different formats,and achieves an accuracy of 99.44%and 97.39%on Portable Document Format(PDF)and office datasets,respectively,and consumes less time during the detection process,which can be effectively applied to the task of detecting malicious documents in real-time.展开更多
BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications...BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.展开更多
Objective:Based on the CNKI database,this study analyzes the current research status and hotspots of the Timing it Right(TIR)Theory in China,providing insights and references for its further development in the field o...Objective:Based on the CNKI database,this study analyzes the current research status and hotspots of the Timing it Right(TIR)Theory in China,providing insights and references for its further development in the field of nursing.Methods:Using bibliometric methods and Citespace software,this study conducts a statistical and visual analysis of publications on TIR Theory from CNKI,focusing on annual publication volumes,author collaboration networks,high-frequency keywords,and emergent terms.Results:The study statistically analyzed the time distribution and research hotspots of 117 relevant papers.The annual publication volume shows a gradual upward trend,though the overall volume remains low.High-frequency keywords such as“family nursing,”“quality of life,”“acute myocardial infarction,”and“stroke”form the core research themes.Conclusion:Research on TIR Theory in China’s nursing field is still in the exploratory stage,and its attention and emphasis need to be enhanced.As it aligns with modern medical models,its application scope in nursing is expanding,promoting the high-quality,scientific,and diversified development of nursing services in China.展开更多
In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytic...In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytical studies based on the examination of journal papers and review papers within the Web of Science(WOS)database.The objective is to provide a reference point for research in related fields.The findings indicate a sustained expansion in PBL research output at universities,with the United States accounting for most documents in the field,while European research institutions such as Aalborg University and Maastricht University are at the forefront.Nevertheless,the density of collaborative networks between authors is relatively low,and cross-institutional and interdisciplinary collaboration still requires further strengthening.The majority of research results are published in academic journals such as Academic Medicine and the International Journal of Sustainability in Higher Education.Presently,the focal point of PBL research in colleges and universities is undergoing a transition from a“single-discipline focus”to an“interdisciplinary integration.”This integration is profoundly intertwined with the nascent fields of modern educational technology and education for sustainable development,thereby offering a novel avenue for the advancement of pedagogical approaches and educational equity.展开更多
Rehabilitation training is believed to be an effectual strategy that canreduce the risk of dysfunction caused by spasticity.However,achieving visualizationrehabilitation training for patients remains clinically challe...Rehabilitation training is believed to be an effectual strategy that canreduce the risk of dysfunction caused by spasticity.However,achieving visualizationrehabilitation training for patients remains clinically challenging.Herein,wepropose visual rehabilitation training system including iontronic meta-fabrics withskin-friendly and large matrix features,as well as high-resolution image modules fordistribution of human muscle tension.Attributed to the dynamic connection and dissociationof the meta-fabric,the fabric exhibits outstanding tactile sensing properties,such as wide tactile sensing range(0~300 kPa)and high-resolution tactile perception(50 Pa or 0.058%).Meanwhile,thanks to the differential capillary effect,the meta-fabric exhibits a“hitting three birds with one stone”property(dryness wearing experience,long working time and cooling sensing).Based on this,the fabrics can be integrated with garmentsand advanced data analysis systems to manufacture a series of large matrix structure(40×40,1600 sensing units)training devices.Significantly,the tunability of piezo-ionic dynamics of the meta-fabric and the programmability of high-resolution imaging modules allowthis visualization training strategy extendable to various common disease monitoring.Therefore,we believe that our study overcomes theconstraint of standard spasticity rehabilitation training devices in terms of visual display and paves the way for future smart healthcare.展开更多
Objective The study of medicine formulas is a core component of traditional Chinese medicine(TCM),yet traditional learning methods often lack interactivity and contextual understanding,making it challenging for beginn...Objective The study of medicine formulas is a core component of traditional Chinese medicine(TCM),yet traditional learning methods often lack interactivity and contextual understanding,making it challenging for beginners to grasp the intricate composition rules of formulas.To address this gap,we introduce Formula-S,a situated visualization method for TCM formula learning in augmented reality(AR)and evaluate its performance.This study aims to evaluate the effectiveness of Formula-S in enhancing TCM formula learning for beginners by comparing it with traditional text-based formula learning and web-based visualization.Methods Formula-S is an interactive AR tool designed for TCM formula learning,featuring three modes(3D,Web,and Table).The dataset included TCM formulas and herb properties extracted from authoritative references,including textbook and the SymMap database.In Formula-S,the hierarchical visualization of the formulas as herbal medicine compositions,is linked to the multidimensional herb attribute visualization and embedded in the real world,where real herb samples are presented.To evaluate its effectiveness,a controlled study(n=30)was conducted.Participants who had no formal TCM knowledge were tasked with herbal medicine identification,formula composition,and recognition.In the study,participants interacted with the AR tool through HoloLens 2.Data were collected on both task performance(accuracy and response time)and user experience,with a focus on task efficiency,accuracy,and user preference across the different learning modes.Results The situated visualization method of Formula-S had comparable accuracy to other methods but shorter response time for herbal formula learning tasks.Regarding user experience,our new approach demonstrated the highest system usability and lowest task load,effectively reducing cognitive load and allowing users to complete tasks with greater ease and efficiency.Participants reported that Formula-S enhanced their learning experience through its intuitive interface and immersive AR environment,suggesting this approach offers usability advantages for TCM education.Conclusions The situated visualization method in Formula-S offers more efficient and accurate searching capabilities compared to traditional and web-based methods.Additionally,it provides superior contextual understanding of TCM formulas,making it a promising new solution for TCM learning.展开更多
Applying the Public-Private Partnership(PPP)model is indispensable in creating new economic growth points in the public service sector.However,there is still a lack of research on mapping the application of the PPP mo...Applying the Public-Private Partnership(PPP)model is indispensable in creating new economic growth points in the public service sector.However,there is still a lack of research on mapping the application of the PPP model in the new era and context.Therefore,based on reviewing the characteristics and development concepts of the PPP model,this paper uses CiteSpace software to analyze the sample authors,journals,and regions in the Scopus database.This paper aims to explore the current development status,research paradigms,and research gap as well as future trends of the PPP model.The results show that(1)The focus of PPP research has shifted from traditional models such as Build-Operate-Transfer(BOT)and Private Finance Initiatives(PFI)to contemporary themes such as risk management,policy analysis,and project governance.Subsequent research(2014-2018)has emphasized the importance of governance and regulatory frameworks to improve PPP outcomes.(2)The growing academic interest in PPP development in China accounts for 28.78%of the total publications.This surge reflects China's rapid economic growth and highlights the interplay between government regulation and private financing.Key research themes include risk management,performance evaluation,contractual flexibility,and financing mechanisms,particularly concerning the BOT model.(3)Effective risk management,relationship dynamics,and innovative financing strategies are key components of a strong PPP knowledge framework.Collaborative risk sharing and strong relationships between public and private entities are key to project success,and strategic financing partnerships are necessary to cope with the complexity of large infrastructure projects.展开更多
The rapid advancement of building information modeling(BIM)technology has garnered significant interest regarding its application within the domain of landscape engineering.BIM technology,as a construction and managem...The rapid advancement of building information modeling(BIM)technology has garnered significant interest regarding its application within the domain of landscape engineering.BIM technology,as a construction and management tool that integrates digitization and visualization,has demonstrated considerable advantages in enhancing project quality,reducing costs,and improving collaborative efficiency.This study aims to systematically investigate the application and developmental trends of BIM visualization technology within the field of landscape engineering.Through an analysis of technological advancements and industry dynamics over the past decade,it has been observed that BIM visualization technology is intricately linked with green building practices,sustainable construction methods,and the development of smart cities within the context of landscape engineering projects.The technology also possesses significant potential for application in the planning and design of landscape engineering,construction management,and project maintenance.The convenience of visualization enhances the expressive capacity of the design scheme,improves communication efficiency between the involved parties,and mitigates the costs and time inefficiencies associated with design modifications.By drawing on the successful experiences of other industries and integrating them with the unique characteristics of landscape engineering,BIM visualization technology is poised to assume a more significant role within this field.This integration is expected to advance the entire industry towards greater intelligence and informatization,while simultaneously enhancing the efficiency and quality of design,construction,and maintenance processes.展开更多
The advent of the big data era has made data visualization a crucial tool for enhancing the efficiency and insights of data analysis. This theoretical research delves into the current applications and potential future...The advent of the big data era has made data visualization a crucial tool for enhancing the efficiency and insights of data analysis. This theoretical research delves into the current applications and potential future trends of data visualization in big data analysis. The article first systematically reviews the theoretical foundations and technological evolution of data visualization, and thoroughly analyzes the challenges faced by visualization in the big data environment, such as massive data processing, real-time visualization requirements, and multi-dimensional data display. Through extensive literature research, it explores innovative application cases and theoretical models of data visualization in multiple fields including business intelligence, scientific research, and public decision-making. The study reveals that interactive visualization, real-time visualization, and immersive visualization technologies may become the main directions for future development and analyzes the potential of these technologies in enhancing user experience and data comprehension. The paper also delves into the theoretical potential of artificial intelligence technology in enhancing data visualization capabilities, such as automated chart generation, intelligent recommendation of visualization schemes, and adaptive visualization interfaces. The research also focuses on the role of data visualization in promoting interdisciplinary collaboration and data democratization. Finally, the paper proposes theoretical suggestions for promoting data visualization technology innovation and application popularization, including strengthening visualization literacy education, developing standardized visualization frameworks, and promoting open-source sharing of visualization tools. This study provides a comprehensive theoretical perspective for understanding the importance of data visualization in the big data era and its future development directions.展开更多
BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional mul...BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.展开更多
High-strength steels are mainly composed of medium-or low-temperature microstructures,such as bainite or martensite,with coherent transformation characteristics.This type of microstructure has a high density of disloc...High-strength steels are mainly composed of medium-or low-temperature microstructures,such as bainite or martensite,with coherent transformation characteristics.This type of microstructure has a high density of dislocations and fine crystallographic structural units,which ease the coordinated matching of high strength,toughness,and plasticity.Meanwhile,given its excellent welding perform-ance,high-strength steel has been widely used in major engineering constructions,such as pipelines,ships,and bridges.However,visual-ization and digitization of the effective units of these coherent transformation structures using traditional methods(optical microscopy and scanning electron microscopy)is difficult due to their complex morphology.Moreover,the establishment of quantitative relationships with macroscopic mechanical properties and key process parameters presents additional difficulty.This article reviews the latest progress in microstructural visualization and digitization of high-strength steel,with a focus on the application of crystallographic methods in the development of high-strength steel plates and welding.We obtained the crystallographic data(Euler angle)of the transformed microstruc-tures through electron back-scattering diffraction and combined them with the calculation of inverse transformation from bainite or martensite to austenite to determine the reconstruction of high-temperature parent austenite and orientation relationship(OR)during con-tinuous cooling transformation.Furthermore,visualization of crystallographic packets,blocks,and variants based on actual OR and digit-ization of various grain boundaries can be effectively completed to establish quantitative relationships with alloy composition and key process parameters,thereby providing reverse design guidance for the development of high-strength steel.展开更多
BACKGROUND When exposed to high-altitude environments,the cardiovascular system undergoes various changes,the performance and mechanisms of which remain controversial.AIM To summarize the latest research advancements ...BACKGROUND When exposed to high-altitude environments,the cardiovascular system undergoes various changes,the performance and mechanisms of which remain controversial.AIM To summarize the latest research advancements and hot research points in the cardiovascular system at high altitude by conducting a bibliometric and visualization analysis.METHODS The literature was systematically retrieved and filtered using the Web of Science Core Collection of Science Citation Index Expanded.A visualization analysis of the identified publications was conducted employing CiteSpace and VOSviewer.RESULTS A total of 1674 publications were included in the study,with an observed annual increase in the number of publications spanning from 1990 to 2022.The United States of America emerged as the predominant contributor,while Universidad Peruana Cayetano Heredia stood out as the institution with the highest publication output.Notably,Jean-Paul Richalet demonstrated the highest productivity among researchers focusing on the cardiovascular system at high altitude.Furthermore,Peter Bärtsch emerged as the author with the highest number of cited articles.Keyword analysis identified hypoxia,exercise,acclimatization,acute and chronic mountain sickness,pulmonary hypertension,metabolism,and echocardiography as the primary research hot research points and emerging directions in the study of the cardiovascular system at high altitude.CONCLUSION Over the past 32 years,research on the cardiovascular system in high-altitude regions has been steadily increasing.Future research in this field may focus on areas such as hypoxia adaptation,metabolism,and cardiopulmonary exercise.Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.展开更多
●AIM:To determine the teaching effects of a real-time three dimensional(3D)visualization system in the operating room for early-stage phacoemulsification training.●METHODS:A total of 10 ophthalmology residents of th...●AIM:To determine the teaching effects of a real-time three dimensional(3D)visualization system in the operating room for early-stage phacoemulsification training.●METHODS:A total of 10 ophthalmology residents of the first-year postgraduate were included.All the residents were novices to cataract surgery.Real-time cataract surgical observations were performed using a custom-built 3D visualization system.The training lasted 4wk(32h)in all.A modified International Council of Ophthalmology’s Ophthalmology Surgical Competency Assessment Rubric(ICO-OSCAR)containing 4 specific steps of cataract surgery was applied.The self-assessment(self)and expert-assessment(expert)were performed through the microsurgical attempts in the wet lab for each participant.●RESULTS:Compared with pre-training assessments(self 3.2±0.8,expert 2.5±0.6),the overall mean scores of posttraining(self 5.2±0.4,expert 4.7±0.6)were significantly improved after real-time observation training of 3D visualization system(P<0.05).Scores of 4 surgical items were significantly improved both self and expert assessment after training(P<0.05).●CONCLUSION:The 3D observation training provides novice ophthalmic residents with a better understanding of intraocular microsurgical techniques.It is a useful tool to improve teaching efficiency of surgical education.展开更多
Objective To investigate the human body’s complex system,and classify and characterize the human body’s health states with“a comprehensive integrated method from qualitative to quantitative”.Methods This paper int...Objective To investigate the human body’s complex system,and classify and characterize the human body’s health states with“a comprehensive integrated method from qualitative to quantitative”.Methods This paper introduces the concept of“order parameters”and proposes a method for establishing an order parameter model of gas discharge visualization(GDV)based on the principle of“mastering both permanence and change(MBPC)”.The method involved the fol-lowing three steps.First,average luminous intensity(I)and average area(S)of the GDV im-ages were calculated to construct the phase space,and the score of the health questionnaire was calculated as the health deviation index(H).Second,the k-means++clustering method was employed to identify subclasses with the same health characteristics based on the data samples,and to statistically determine the symptom-specific frequencies of the subclasses.Third,the distance(d)between each sample and the“ideal health state”,which determined in the phase space of each subclass,was calculated as an order parameter describing the health imbalance,and a linear mapping was established between the d and the H.Further,the health implications of GDV signals were explored by analyzing subclass symptom profiles.We also compare the mean square error(MSE)with classification methods based on age,gen-der,and body mass index(BMI)indices to verify that the phase space possesses the ability to portray the health status of the human body.Results This study preliminarily tested the reliability of the order parameter model on data samples provided by 20 participants.Based on the discovered linear law,the current model can use d calculated by measuring the GDV signal to predict H(R^(2)>0.77).Combined with the symptom profiles of the subclasses,we explain the classification basis of the phase space based on the pattern identification.Compared with common classification methods based on age,gender,BMI,etc.,the MSE of phase space-based classification was reduced by an order of magnitude.Conclusion In this study,the GDV order parameter model based on MBPC can identify sub-classes and characterize individual health levels,and explore the TCM health meanings of the GDV signals by using subjective-objective methods,which holds significance for establishing mathematical models from TCM diagnosis principles to interpret human body signals.展开更多
Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based di...Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based diagnosis,teaching,and research.Although the retrieval accuracy has largely improved,there has been limited development toward visualizing important image features that indicate the similarity of retrieved images.Despite the prevalence of 3D volumetric data in medical imaging such as computed tomography(CT),current CBIR systems still rely on 2D cross-sectional views for the visualization of retrieved images.Such 2D visualization requires users to browse through the image stacks to confirm the similarity of the retrieved images and often involves mental reconstruction of 3D information,including the size,shape,and spatial relations of multiple structures.This process is time-consuming and reliant on users'experience.Methods In this study,we proposed an importance-aware 3D volume visualization method.The rendering parameters were automatically optimized to maximize the visibility of important structures that were detected and prioritized in the retrieval process.We then integrated the proposed visualization into a CBIR system,thereby complementing the 2D cross-sectional views for relevance feedback and further analyses.Results Our preliminary results demonstrate that 3D visualization can provide additional information using multimodal positron emission tomography and computed tomography(PETCT)images of a non-small cell lung cancer dataset.展开更多
BACKGROUND Laparoscopic gastrectomy for esophagogastric junction(EGJ)carcinoma enables the removal of the carcinoma at the junction between the stomach and esophagus while preserving the gastric function,thereby provi...BACKGROUND Laparoscopic gastrectomy for esophagogastric junction(EGJ)carcinoma enables the removal of the carcinoma at the junction between the stomach and esophagus while preserving the gastric function,thereby providing patients with better treatment outcomes and quality of life.Nonetheless,this surgical technique also presents some challenges and limitations.Therefore,three-dimensional reconstruction visualization technology(3D RVT)has been introduced into the procedure,providing doctors with more comprehensive and intuitive anatomical information that helps with surgical planning,navigation,and outcome evaluation.AIM To discuss the application and advantages of 3D RVT in precise laparoscopic resection of EGJ carcinomas.METHODS Data were obtained from the electronic or paper-based medical records at The First Affiliated Hospital of Hebei North University from January 2020 to June 2022.A total of 120 patients diagnosed with EGJ carcinoma were included in the study.Of these,68 underwent laparoscopic resection after computed tomography(CT)-enhanced scanning and were categorized into the 2D group,whereas 52 underwent laparoscopic resection after CT-enhanced scanning and 3D RVT and were categorized into the 3D group.This study had two outcome measures:the deviation between tumor-related factors(such as maximum tumor diameter and infiltration length)in 3D RVT and clinical reality,and surgical outcome indicators(such as operative time,intraoperative blood loss,number of lymph node dissections,R0 resection rate,postoperative hospital stay,postoperative gas discharge time,drainage tube removal time,and related complications)between the 2D and 3D groups.RESULTS Among patients included in the 3D group,27 had a maximum tumor diameter of less than 3 cm,whereas 25 had a diameter of 3 cm or more.In actual surgical observations,24 had a diameter of less than 3 cm,whereas 28 had a diameter of 3 cm or more.The findings were consistent between the two methods(χ^(2)=0.346,P=0.556),with a kappa consistency coefficient of 0.808.With respect to infiltration length,in the 3D group,23 patients had a length of less than 5 cm,whereas 29 had a length of 5 cm or more.In actual surgical observations,20 cases had a length of less than 5 cm,whereas 32 had a length of 5 cm or more.The findings were consistent between the two methods(χ^(2)=0.357,P=0.550),with a kappa consistency coefficient of 0.486.Pearson correlation analysis showed that the maximum tumor diameter and infiltration length measured using 3D RVT were positively correlated with clinical observations during surgery(r=0.814 and 0.490,both P<0.05).The 3D group had a shorter operative time(157.02±8.38 vs 183.16±23.87),less intraoperative blood loss(83.65±14.22 vs 110.94±22.05),and higher number of lymph node dissections(28.98±2.82 vs 23.56±2.77)and R0 resection rate(80.77%vs 61.64%)than the 2D group.Furthermore,the 3D group had shorter hospital stay[8(8,9)vs 13(14,16)],time to gas passage[3(3,4)vs 4(5,5)],and drainage tube removal time[4(4,5)vs 6(6,7)]than the 2D group.The complication rate was lower in the 3D group(11.54%)than in the 2D group(26.47%)(χ^(2)=4.106,P<0.05).CONCLUSION Using 3D RVT,doctors can gain a more comprehensive and intuitive understanding of the anatomy and related lesions of EGJ carcinomas,thus enabling more accurate surgical planning.展开更多
BACKGROUND In the rapidly evolving landscape of psychiatric research,2023 marked another year of significant progress globally,with the World Journal of Psychiatry(WJP)experiencing notable expansion and influence.AIM ...BACKGROUND In the rapidly evolving landscape of psychiatric research,2023 marked another year of significant progress globally,with the World Journal of Psychiatry(WJP)experiencing notable expansion and influence.AIM To conduct a comprehensive visualization and analysis of the articles published in the WJP throughout 2023.By delving into these publications,the aim is to deter-mine the valuable insights that can illuminate pathways for future research endeavors in the field of psychiatry.METHODS A selection process led to the inclusion of 107 papers from the WJP published in 2023,forming the dataset for the analysis.Employing advanced visualization techniques,this study mapped the knowledge domains represented in these papers.RESULTS The findings revealed a prevalent focus on key topics such as depression,mental health,anxiety,schizophrenia,and the impact of coronavirus disease 2019.Additionally,through keyword clustering,it became evident that these papers were predominantly focused on exploring mental health disorders,depression,anxiety,schizophrenia,and related factors.Noteworthy contributions hailed authors in regions such as China,the United Kingdom,United States,and Turkey.Particularly,the paper garnered the highest number of citations,while the American Psychiatric Association was the most cited reference.CONCLUSION It is recommended that the WJP continue in its efforts to enhance the quality of papers published in the field of psychiatry.Additionally,there is a pressing need to delve into the potential applications of digital interventions and artificial intelligence within the discipline.展开更多
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this...BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.展开更多
Groundwater is a vital component of the hydrological cycle and essential for the sustainable development of ecosystems.Numerical simulation methods are key tools for addressing scientific challenges in groundwater res...Groundwater is a vital component of the hydrological cycle and essential for the sustainable development of ecosystems.Numerical simulation methods are key tools for addressing scientific challenges in groundwater research.This study uses bibliometric visualization analysis to examine the progress and trends in groundwater numerical simulation methods.By analyzing literature indexed in the Web of Science database from January 1990 to February 2023,and employing tools such as Citespace and VOSviewer,we assessed publication volume,research institutions and their collaborations,prolific scholars,keyword clustering,and emerging trends.The findings indicate an overall upward trend in both the number of publications and citations concerning groundwater numerical simulations.Since 2010,the number of publications has tripled compared to the total before 2010,underscoring the increasing significance and potential of numerical simulation methods in groundwater science.China,in particular,has shown remarkable growth in this field over the past decade,surpassing the United States,Canada,and Germany.This progress is closely linked to strong national support and active participation from research institutions,especially the contributions from teams at Hohai University,China University of Geosciences,and the University of Science and Technology of China.Collaboration between research teams is primarily seen between China and the United States,with less noticeable cooperation among other countries,resulting in a diverse and dispersed development pattern.Keyword analysis highlights that international research hotspots include groundwater recharge,karst water,geothermal water migration,seawater intrusion,variable density flow,contaminant and solute transport,pollution remediation,and land subsidence.Looking ahead,groundwater numerical simulations are expected to play a more prominent role in areas such as climate change,surface water-groundwater interactions,the impact of groundwater nitrates on the environment and health,submarine groundwater discharge,ecological water use,groundwater management,and risk prevention.展开更多
基金supported by the Natural Science Foundation of Henan Province(Grant No.242300420297)awarded to Yi Sun.
文摘With the development of anti-virus technology,malicious documents have gradually become the main pathway of Advanced Persistent Threat(APT)attacks,therefore,the development of effective malicious document classifiers has become particularly urgent.Currently,detection methods based on document structure and behavioral features encounter challenges in feature engineering,these methods not only have limited accuracy,but also consume large resources,and usually can only detect documents in specific formats,which lacks versatility and adaptability.To address such problems,this paper proposes a novel malicious document detection method-visualizing documents as GGE images(Grayscale,Grayscale matrix,Entropy).The GGE method visualizes the original byte sequence of the malicious document as a grayscale image,the information entropy sequence of the document as an entropy image,and at the same time,the grayscale level co-occurrence matrix and the texture and spatial information stored in it are converted into grayscale matrix image,and fuses the three types of images to get the GGE color image.The Convolutional Block Attention Module-EfficientNet-B0(CBAM-EfficientNet-B0)model is then used for classification,combining transfer learning and applying the pre-trained model on the ImageNet dataset to the feature extraction process of GGE images.As shown in the experimental results,the GGE method has superior performance compared with other methods,which is suitable for detecting malicious documents in different formats,and achieves an accuracy of 99.44%and 97.39%on Portable Document Format(PDF)and office datasets,respectively,and consumes less time during the detection process,which can be effectively applied to the task of detecting malicious documents in real-time.
基金Supported by the National Natural Science Foundation of China,No.82105018 and No.81903950.
文摘BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.
文摘Objective:Based on the CNKI database,this study analyzes the current research status and hotspots of the Timing it Right(TIR)Theory in China,providing insights and references for its further development in the field of nursing.Methods:Using bibliometric methods and Citespace software,this study conducts a statistical and visual analysis of publications on TIR Theory from CNKI,focusing on annual publication volumes,author collaboration networks,high-frequency keywords,and emergent terms.Results:The study statistically analyzed the time distribution and research hotspots of 117 relevant papers.The annual publication volume shows a gradual upward trend,though the overall volume remains low.High-frequency keywords such as“family nursing,”“quality of life,”“acute myocardial infarction,”and“stroke”form the core research themes.Conclusion:Research on TIR Theory in China’s nursing field is still in the exploratory stage,and its attention and emphasis need to be enhanced.As it aligns with modern medical models,its application scope in nursing is expanding,promoting the high-quality,scientific,and diversified development of nursing services in China.
文摘In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytical studies based on the examination of journal papers and review papers within the Web of Science(WOS)database.The objective is to provide a reference point for research in related fields.The findings indicate a sustained expansion in PBL research output at universities,with the United States accounting for most documents in the field,while European research institutions such as Aalborg University and Maastricht University are at the forefront.Nevertheless,the density of collaborative networks between authors is relatively low,and cross-institutional and interdisciplinary collaboration still requires further strengthening.The majority of research results are published in academic journals such as Academic Medicine and the International Journal of Sustainability in Higher Education.Presently,the focal point of PBL research in colleges and universities is undergoing a transition from a“single-discipline focus”to an“interdisciplinary integration.”This integration is profoundly intertwined with the nascent fields of modern educational technology and education for sustainable development,thereby offering a novel avenue for the advancement of pedagogical approaches and educational equity.
基金supported by the National Key Research and Development Program(2022YFB3805800)National Natural Science Foundation of China(52473307,22208178,62301290)+9 种基金Taishan Scholar Program of Shandong Province in China(tsqn202211116)Shandong Provincial Universities Youth Innovation Technology Plan Team(2023KJ223)Natural Science Foundation of Shandong Province of China(ZR2023YQ037,ZR2020QE074,ZR2023QE043,ZR2022QE174)Shandong Province Science and Technology Small and Medium sized Enterprise Innovation Ability Enhancement Project(2023TSGC0344,2023TSGC1006)Natural Science Foundation of Qingdao(23-2-1-249-zyyd-jch,24-4-4-zrjj-56-jch)Anhui Province Postdoctoral Researcher Research Activity Funding Project(2023B706)Qingdao Key Technology Research and Industrialization Demonstration Projects(23-1-7-zdfn-2-hz)Qingdao Shinan District Science and Technology Plan Project(2022-3-005-DZ)Suqian Key Research and Development Plan(H202310)Jinan City-School Integration Development Strategy Project for the Year 2023 under Grant(JNSX2023088).
文摘Rehabilitation training is believed to be an effectual strategy that canreduce the risk of dysfunction caused by spasticity.However,achieving visualizationrehabilitation training for patients remains clinically challenging.Herein,wepropose visual rehabilitation training system including iontronic meta-fabrics withskin-friendly and large matrix features,as well as high-resolution image modules fordistribution of human muscle tension.Attributed to the dynamic connection and dissociationof the meta-fabric,the fabric exhibits outstanding tactile sensing properties,such as wide tactile sensing range(0~300 kPa)and high-resolution tactile perception(50 Pa or 0.058%).Meanwhile,thanks to the differential capillary effect,the meta-fabric exhibits a“hitting three birds with one stone”property(dryness wearing experience,long working time and cooling sensing).Based on this,the fabrics can be integrated with garmentsand advanced data analysis systems to manufacture a series of large matrix structure(40×40,1600 sensing units)training devices.Significantly,the tunability of piezo-ionic dynamics of the meta-fabric and the programmability of high-resolution imaging modules allowthis visualization training strategy extendable to various common disease monitoring.Therefore,we believe that our study overcomes theconstraint of standard spasticity rehabilitation training devices in terms of visual display and paves the way for future smart healthcare.
文摘Objective The study of medicine formulas is a core component of traditional Chinese medicine(TCM),yet traditional learning methods often lack interactivity and contextual understanding,making it challenging for beginners to grasp the intricate composition rules of formulas.To address this gap,we introduce Formula-S,a situated visualization method for TCM formula learning in augmented reality(AR)and evaluate its performance.This study aims to evaluate the effectiveness of Formula-S in enhancing TCM formula learning for beginners by comparing it with traditional text-based formula learning and web-based visualization.Methods Formula-S is an interactive AR tool designed for TCM formula learning,featuring three modes(3D,Web,and Table).The dataset included TCM formulas and herb properties extracted from authoritative references,including textbook and the SymMap database.In Formula-S,the hierarchical visualization of the formulas as herbal medicine compositions,is linked to the multidimensional herb attribute visualization and embedded in the real world,where real herb samples are presented.To evaluate its effectiveness,a controlled study(n=30)was conducted.Participants who had no formal TCM knowledge were tasked with herbal medicine identification,formula composition,and recognition.In the study,participants interacted with the AR tool through HoloLens 2.Data were collected on both task performance(accuracy and response time)and user experience,with a focus on task efficiency,accuracy,and user preference across the different learning modes.Results The situated visualization method of Formula-S had comparable accuracy to other methods but shorter response time for herbal formula learning tasks.Regarding user experience,our new approach demonstrated the highest system usability and lowest task load,effectively reducing cognitive load and allowing users to complete tasks with greater ease and efficiency.Participants reported that Formula-S enhanced their learning experience through its intuitive interface and immersive AR environment,suggesting this approach offers usability advantages for TCM education.Conclusions The situated visualization method in Formula-S offers more efficient and accurate searching capabilities compared to traditional and web-based methods.Additionally,it provides superior contextual understanding of TCM formulas,making it a promising new solution for TCM learning.
基金supported by the following projects:Philosophy and Social Sciences Planning Leading Group of Guangdong Province(Project No.GD21CGL31)Research Projects of Department of Education of Guangdong Province(Project No.2023WCXTD037).
文摘Applying the Public-Private Partnership(PPP)model is indispensable in creating new economic growth points in the public service sector.However,there is still a lack of research on mapping the application of the PPP model in the new era and context.Therefore,based on reviewing the characteristics and development concepts of the PPP model,this paper uses CiteSpace software to analyze the sample authors,journals,and regions in the Scopus database.This paper aims to explore the current development status,research paradigms,and research gap as well as future trends of the PPP model.The results show that(1)The focus of PPP research has shifted from traditional models such as Build-Operate-Transfer(BOT)and Private Finance Initiatives(PFI)to contemporary themes such as risk management,policy analysis,and project governance.Subsequent research(2014-2018)has emphasized the importance of governance and regulatory frameworks to improve PPP outcomes.(2)The growing academic interest in PPP development in China accounts for 28.78%of the total publications.This surge reflects China's rapid economic growth and highlights the interplay between government regulation and private financing.Key research themes include risk management,performance evaluation,contractual flexibility,and financing mechanisms,particularly concerning the BOT model.(3)Effective risk management,relationship dynamics,and innovative financing strategies are key components of a strong PPP knowledge framework.Collaborative risk sharing and strong relationships between public and private entities are key to project success,and strategic financing partnerships are necessary to cope with the complexity of large infrastructure projects.
基金Sponsored by Building Structure Key Laboratory Project of Colleges and Universities in Anhui Province(KLBSZD202105)Key Projects of Scientific Research Programs(Natural Science)of Higher Education Institutions in Anhui Province(2022AH051861)Research Team Program of Anhui Xinhua University(kytd202202).
文摘The rapid advancement of building information modeling(BIM)technology has garnered significant interest regarding its application within the domain of landscape engineering.BIM technology,as a construction and management tool that integrates digitization and visualization,has demonstrated considerable advantages in enhancing project quality,reducing costs,and improving collaborative efficiency.This study aims to systematically investigate the application and developmental trends of BIM visualization technology within the field of landscape engineering.Through an analysis of technological advancements and industry dynamics over the past decade,it has been observed that BIM visualization technology is intricately linked with green building practices,sustainable construction methods,and the development of smart cities within the context of landscape engineering projects.The technology also possesses significant potential for application in the planning and design of landscape engineering,construction management,and project maintenance.The convenience of visualization enhances the expressive capacity of the design scheme,improves communication efficiency between the involved parties,and mitigates the costs and time inefficiencies associated with design modifications.By drawing on the successful experiences of other industries and integrating them with the unique characteristics of landscape engineering,BIM visualization technology is poised to assume a more significant role within this field.This integration is expected to advance the entire industry towards greater intelligence and informatization,while simultaneously enhancing the efficiency and quality of design,construction,and maintenance processes.
文摘The advent of the big data era has made data visualization a crucial tool for enhancing the efficiency and insights of data analysis. This theoretical research delves into the current applications and potential future trends of data visualization in big data analysis. The article first systematically reviews the theoretical foundations and technological evolution of data visualization, and thoroughly analyzes the challenges faced by visualization in the big data environment, such as massive data processing, real-time visualization requirements, and multi-dimensional data display. Through extensive literature research, it explores innovative application cases and theoretical models of data visualization in multiple fields including business intelligence, scientific research, and public decision-making. The study reveals that interactive visualization, real-time visualization, and immersive visualization technologies may become the main directions for future development and analyzes the potential of these technologies in enhancing user experience and data comprehension. The paper also delves into the theoretical potential of artificial intelligence technology in enhancing data visualization capabilities, such as automated chart generation, intelligent recommendation of visualization schemes, and adaptive visualization interfaces. The research also focuses on the role of data visualization in promoting interdisciplinary collaboration and data democratization. Finally, the paper proposes theoretical suggestions for promoting data visualization technology innovation and application popularization, including strengthening visualization literacy education, developing standardized visualization frameworks, and promoting open-source sharing of visualization tools. This study provides a comprehensive theoretical perspective for understanding the importance of data visualization in the big data era and its future development directions.
基金Supported by The Key Medical Specialty Nurturing Program of Foshan During The 14th Five-Year Plan Period,No.FSPY145205The Medical Research Project of Foshan Health Bureau,No.20230814A010024+1 种基金The Guangzhou Science and Technology Plan Project,No.202102010251the Guangdong Science and Technology Program,No.2017ZC0222.
文摘BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.
基金supported by the National Key Research and Development Project of China(Nos.2022YFB3708200 and 2021YFB3703500)the National Natural Science Foundation of China(Nos.52271089 and 52001023).
文摘High-strength steels are mainly composed of medium-or low-temperature microstructures,such as bainite or martensite,with coherent transformation characteristics.This type of microstructure has a high density of dislocations and fine crystallographic structural units,which ease the coordinated matching of high strength,toughness,and plasticity.Meanwhile,given its excellent welding perform-ance,high-strength steel has been widely used in major engineering constructions,such as pipelines,ships,and bridges.However,visual-ization and digitization of the effective units of these coherent transformation structures using traditional methods(optical microscopy and scanning electron microscopy)is difficult due to their complex morphology.Moreover,the establishment of quantitative relationships with macroscopic mechanical properties and key process parameters presents additional difficulty.This article reviews the latest progress in microstructural visualization and digitization of high-strength steel,with a focus on the application of crystallographic methods in the development of high-strength steel plates and welding.We obtained the crystallographic data(Euler angle)of the transformed microstruc-tures through electron back-scattering diffraction and combined them with the calculation of inverse transformation from bainite or martensite to austenite to determine the reconstruction of high-temperature parent austenite and orientation relationship(OR)during con-tinuous cooling transformation.Furthermore,visualization of crystallographic packets,blocks,and variants based on actual OR and digit-ization of various grain boundaries can be effectively completed to establish quantitative relationships with alloy composition and key process parameters,thereby providing reverse design guidance for the development of high-strength steel.
基金Supported by Natural Science Foundation of Sichuan Province,No.2022NSFSC1295the 2021 Annal Project of the General Hospital of Western Theater Command,No.2021-XZYG-B31.
文摘BACKGROUND When exposed to high-altitude environments,the cardiovascular system undergoes various changes,the performance and mechanisms of which remain controversial.AIM To summarize the latest research advancements and hot research points in the cardiovascular system at high altitude by conducting a bibliometric and visualization analysis.METHODS The literature was systematically retrieved and filtered using the Web of Science Core Collection of Science Citation Index Expanded.A visualization analysis of the identified publications was conducted employing CiteSpace and VOSviewer.RESULTS A total of 1674 publications were included in the study,with an observed annual increase in the number of publications spanning from 1990 to 2022.The United States of America emerged as the predominant contributor,while Universidad Peruana Cayetano Heredia stood out as the institution with the highest publication output.Notably,Jean-Paul Richalet demonstrated the highest productivity among researchers focusing on the cardiovascular system at high altitude.Furthermore,Peter Bärtsch emerged as the author with the highest number of cited articles.Keyword analysis identified hypoxia,exercise,acclimatization,acute and chronic mountain sickness,pulmonary hypertension,metabolism,and echocardiography as the primary research hot research points and emerging directions in the study of the cardiovascular system at high altitude.CONCLUSION Over the past 32 years,research on the cardiovascular system in high-altitude regions has been steadily increasing.Future research in this field may focus on areas such as hypoxia adaptation,metabolism,and cardiopulmonary exercise.Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.
基金Supported by research grants from the National Key Research and Development Program of China(No.2020YFE0204400)the National Natural Science Foundation of China(No.82271042+1 种基金No.52203191)the Zhejiang Province Key Research and Development Program(No.2023C03090).
文摘●AIM:To determine the teaching effects of a real-time three dimensional(3D)visualization system in the operating room for early-stage phacoemulsification training.●METHODS:A total of 10 ophthalmology residents of the first-year postgraduate were included.All the residents were novices to cataract surgery.Real-time cataract surgical observations were performed using a custom-built 3D visualization system.The training lasted 4wk(32h)in all.A modified International Council of Ophthalmology’s Ophthalmology Surgical Competency Assessment Rubric(ICO-OSCAR)containing 4 specific steps of cataract surgery was applied.The self-assessment(self)and expert-assessment(expert)were performed through the microsurgical attempts in the wet lab for each participant.●RESULTS:Compared with pre-training assessments(self 3.2±0.8,expert 2.5±0.6),the overall mean scores of posttraining(self 5.2±0.4,expert 4.7±0.6)were significantly improved after real-time observation training of 3D visualization system(P<0.05).Scores of 4 surgical items were significantly improved both self and expert assessment after training(P<0.05).●CONCLUSION:The 3D observation training provides novice ophthalmic residents with a better understanding of intraocular microsurgical techniques.It is a useful tool to improve teaching efficiency of surgical education.
基金Program of Office of Science and Technology Development,Peking University(3124-2021|-L-w6).
文摘Objective To investigate the human body’s complex system,and classify and characterize the human body’s health states with“a comprehensive integrated method from qualitative to quantitative”.Methods This paper introduces the concept of“order parameters”and proposes a method for establishing an order parameter model of gas discharge visualization(GDV)based on the principle of“mastering both permanence and change(MBPC)”.The method involved the fol-lowing three steps.First,average luminous intensity(I)and average area(S)of the GDV im-ages were calculated to construct the phase space,and the score of the health questionnaire was calculated as the health deviation index(H).Second,the k-means++clustering method was employed to identify subclasses with the same health characteristics based on the data samples,and to statistically determine the symptom-specific frequencies of the subclasses.Third,the distance(d)between each sample and the“ideal health state”,which determined in the phase space of each subclass,was calculated as an order parameter describing the health imbalance,and a linear mapping was established between the d and the H.Further,the health implications of GDV signals were explored by analyzing subclass symptom profiles.We also compare the mean square error(MSE)with classification methods based on age,gen-der,and body mass index(BMI)indices to verify that the phase space possesses the ability to portray the health status of the human body.Results This study preliminarily tested the reliability of the order parameter model on data samples provided by 20 participants.Based on the discovered linear law,the current model can use d calculated by measuring the GDV signal to predict H(R^(2)>0.77).Combined with the symptom profiles of the subclasses,we explain the classification basis of the phase space based on the pattern identification.Compared with common classification methods based on age,gender,BMI,etc.,the MSE of phase space-based classification was reduced by an order of magnitude.Conclusion In this study,the GDV order parameter model based on MBPC can identify sub-classes and characterize individual health levels,and explore the TCM health meanings of the GDV signals by using subjective-objective methods,which holds significance for establishing mathematical models from TCM diagnosis principles to interpret human body signals.
文摘Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based diagnosis,teaching,and research.Although the retrieval accuracy has largely improved,there has been limited development toward visualizing important image features that indicate the similarity of retrieved images.Despite the prevalence of 3D volumetric data in medical imaging such as computed tomography(CT),current CBIR systems still rely on 2D cross-sectional views for the visualization of retrieved images.Such 2D visualization requires users to browse through the image stacks to confirm the similarity of the retrieved images and often involves mental reconstruction of 3D information,including the size,shape,and spatial relations of multiple structures.This process is time-consuming and reliant on users'experience.Methods In this study,we proposed an importance-aware 3D volume visualization method.The rendering parameters were automatically optimized to maximize the visibility of important structures that were detected and prioritized in the retrieval process.We then integrated the proposed visualization into a CBIR system,thereby complementing the 2D cross-sectional views for relevance feedback and further analyses.Results Our preliminary results demonstrate that 3D visualization can provide additional information using multimodal positron emission tomography and computed tomography(PETCT)images of a non-small cell lung cancer dataset.
文摘BACKGROUND Laparoscopic gastrectomy for esophagogastric junction(EGJ)carcinoma enables the removal of the carcinoma at the junction between the stomach and esophagus while preserving the gastric function,thereby providing patients with better treatment outcomes and quality of life.Nonetheless,this surgical technique also presents some challenges and limitations.Therefore,three-dimensional reconstruction visualization technology(3D RVT)has been introduced into the procedure,providing doctors with more comprehensive and intuitive anatomical information that helps with surgical planning,navigation,and outcome evaluation.AIM To discuss the application and advantages of 3D RVT in precise laparoscopic resection of EGJ carcinomas.METHODS Data were obtained from the electronic or paper-based medical records at The First Affiliated Hospital of Hebei North University from January 2020 to June 2022.A total of 120 patients diagnosed with EGJ carcinoma were included in the study.Of these,68 underwent laparoscopic resection after computed tomography(CT)-enhanced scanning and were categorized into the 2D group,whereas 52 underwent laparoscopic resection after CT-enhanced scanning and 3D RVT and were categorized into the 3D group.This study had two outcome measures:the deviation between tumor-related factors(such as maximum tumor diameter and infiltration length)in 3D RVT and clinical reality,and surgical outcome indicators(such as operative time,intraoperative blood loss,number of lymph node dissections,R0 resection rate,postoperative hospital stay,postoperative gas discharge time,drainage tube removal time,and related complications)between the 2D and 3D groups.RESULTS Among patients included in the 3D group,27 had a maximum tumor diameter of less than 3 cm,whereas 25 had a diameter of 3 cm or more.In actual surgical observations,24 had a diameter of less than 3 cm,whereas 28 had a diameter of 3 cm or more.The findings were consistent between the two methods(χ^(2)=0.346,P=0.556),with a kappa consistency coefficient of 0.808.With respect to infiltration length,in the 3D group,23 patients had a length of less than 5 cm,whereas 29 had a length of 5 cm or more.In actual surgical observations,20 cases had a length of less than 5 cm,whereas 32 had a length of 5 cm or more.The findings were consistent between the two methods(χ^(2)=0.357,P=0.550),with a kappa consistency coefficient of 0.486.Pearson correlation analysis showed that the maximum tumor diameter and infiltration length measured using 3D RVT were positively correlated with clinical observations during surgery(r=0.814 and 0.490,both P<0.05).The 3D group had a shorter operative time(157.02±8.38 vs 183.16±23.87),less intraoperative blood loss(83.65±14.22 vs 110.94±22.05),and higher number of lymph node dissections(28.98±2.82 vs 23.56±2.77)and R0 resection rate(80.77%vs 61.64%)than the 2D group.Furthermore,the 3D group had shorter hospital stay[8(8,9)vs 13(14,16)],time to gas passage[3(3,4)vs 4(5,5)],and drainage tube removal time[4(4,5)vs 6(6,7)]than the 2D group.The complication rate was lower in the 3D group(11.54%)than in the 2D group(26.47%)(χ^(2)=4.106,P<0.05).CONCLUSION Using 3D RVT,doctors can gain a more comprehensive and intuitive understanding of the anatomy and related lesions of EGJ carcinomas,thus enabling more accurate surgical planning.
基金Supported by Philosophy and Social Science Foundation of Hunan Province,China,No.23YBJ08China Youth&Children Research Association,No.2023B01Research Project on the Theories and Practice of Hunan Women,No.22YB06.
文摘BACKGROUND In the rapidly evolving landscape of psychiatric research,2023 marked another year of significant progress globally,with the World Journal of Psychiatry(WJP)experiencing notable expansion and influence.AIM To conduct a comprehensive visualization and analysis of the articles published in the WJP throughout 2023.By delving into these publications,the aim is to deter-mine the valuable insights that can illuminate pathways for future research endeavors in the field of psychiatry.METHODS A selection process led to the inclusion of 107 papers from the WJP published in 2023,forming the dataset for the analysis.Employing advanced visualization techniques,this study mapped the knowledge domains represented in these papers.RESULTS The findings revealed a prevalent focus on key topics such as depression,mental health,anxiety,schizophrenia,and the impact of coronavirus disease 2019.Additionally,through keyword clustering,it became evident that these papers were predominantly focused on exploring mental health disorders,depression,anxiety,schizophrenia,and related factors.Noteworthy contributions hailed authors in regions such as China,the United Kingdom,United States,and Turkey.Particularly,the paper garnered the highest number of citations,while the American Psychiatric Association was the most cited reference.CONCLUSION It is recommended that the WJP continue in its efforts to enhance the quality of papers published in the field of psychiatry.Additionally,there is a pressing need to delve into the potential applications of digital interventions and artificial intelligence within the discipline.
文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.
基金supported by the Institute of Hydrogeology and Environmental Geology,China Geological Survey"Coupling analysis of groundwater and land subsidence in typical cities of the North China Plain based on InSAR-GRACE technology"project under Grant No.KY202302the China Geological Survey"Research and promotion of digital water resources survey technology"project under Grant No.DD20230427the"Cloud platform geological survey node operation and maintenance and network security guarantee(Institute of Hydrogeology and Environmental Geology)"project under Grant No.DD20230719.
文摘Groundwater is a vital component of the hydrological cycle and essential for the sustainable development of ecosystems.Numerical simulation methods are key tools for addressing scientific challenges in groundwater research.This study uses bibliometric visualization analysis to examine the progress and trends in groundwater numerical simulation methods.By analyzing literature indexed in the Web of Science database from January 1990 to February 2023,and employing tools such as Citespace and VOSviewer,we assessed publication volume,research institutions and their collaborations,prolific scholars,keyword clustering,and emerging trends.The findings indicate an overall upward trend in both the number of publications and citations concerning groundwater numerical simulations.Since 2010,the number of publications has tripled compared to the total before 2010,underscoring the increasing significance and potential of numerical simulation methods in groundwater science.China,in particular,has shown remarkable growth in this field over the past decade,surpassing the United States,Canada,and Germany.This progress is closely linked to strong national support and active participation from research institutions,especially the contributions from teams at Hohai University,China University of Geosciences,and the University of Science and Technology of China.Collaboration between research teams is primarily seen between China and the United States,with less noticeable cooperation among other countries,resulting in a diverse and dispersed development pattern.Keyword analysis highlights that international research hotspots include groundwater recharge,karst water,geothermal water migration,seawater intrusion,variable density flow,contaminant and solute transport,pollution remediation,and land subsidence.Looking ahead,groundwater numerical simulations are expected to play a more prominent role in areas such as climate change,surface water-groundwater interactions,the impact of groundwater nitrates on the environment and health,submarine groundwater discharge,ecological water use,groundwater management,and risk prevention.
