This study was conducted to determine the effects of yeast cell wall polysaccharides（YCWP） on reproductive performance, serum profiles and milk composition during late gestation and lactation. A total of 96 sows（La...This study was conducted to determine the effects of yeast cell wall polysaccharides（YCWP） on reproductive performance, serum profiles and milk composition during late gestation and lactation. A total of 96 sows（Landrace × Yorkshire） were blocked on a basis of breed, parity（2-3）and their respective d 85 of gestation, and then randomly allotted to the following three dietary treatments： CON（basal diet, treatment 1）, YCWP1（CON＋0.2% YCWP, treatment 2） and YCWP2（CON＋0.4% YCWP, treatment 3）. The experiment lasted from d 85 of gestation to weaning（d 21 of lactation）. Sows fed YCWP diets had lower backfat thickness reduction from postpartum to weaning（ P〈0.05）. The supplementation of YCWP tended to increase litter weight at weaning（P=0.08） compared with CON. The non-lipid and total milk solids in colostrum was improved by YCWP2（P〈0.05）.No differences were observed in milk composition among dietary treatments（ P〉0.05）. The supplementation of YCWP decreased（P〈0.05） the levels of alanine amino transferase（ALT）, aspartate amino transferase（AST）, while it did not affect（ P〉0.05） alkaline phosphatase（ALP）, total protein（TP）,albumin（ALB）, globulin（GLB）, glucose（GLU）, total cholesterol（TC）, triglyceride（TG） or immunoglobulin G（IgG） in the sow serum. The serum IgG of piglets was increased by the YCWP. The levels of serum ALT and AST were reduced（P〈0.05） for suckling piglets in YCWP treatments. Taken together, the results of current studies might indicate beneficial effects of YCWP supplementation to late gestation and lactation diets on the sow productivity by improving litter weight at weaning, reducing backfat loss, and increasing serum IgG concentrations of piglets.展开更多
This study was to investigate the effect of corn naturally contaminated with aflatoxins(AF)under the regulatory level on the growth performance and health of nursery pigs,and the efficiency of yeast cell wall based fe...This study was to investigate the effect of corn naturally contaminated with aflatoxins(AF)under the regulatory level on the growth performance and health of nursery pigs,and the efficiency of yeast cell wall based feed additive(YC)mainly composed ofβ-glucans and mannan oligosaccharide(MOS)(Integral A+,Alltech,Lexington,KY)in prevention of mycotoxicosis.Pigs(60 barrows and 60 gilts at 6.02 ± 0.83kg BW)were randomly allotted to 4 treatments in a randomized complete block design based on a 2×2 factorial arrangement with 10 pens(5 barrow and 5 gilt pens)per treatment and 3 pigs per pen.Pigs were fed experimental diets for 5 wk.First factor was AF(0 or 20 mg/kg in feed)and the second factor was YC(0 or 2 g/kg in feed).Feed intake and body weight were measured weekly,and blood samples were used to measure blood cell counts,immunoglobulin G(Ig G),tumor necrosis factor-a(TNF-a),oxidative damage status,and serological evaluation related to liver health.Aflatoxin decreased(P<0.05)the number of platelet count(247.4 to 193.5×10~3/μL),and it also tended to increase the level of albumin(P=0.055,3.46 to 3.63 g/d L),albumin:globulin ratio(P=0.050,2.09 to 2.37),and Ca(P=0.080,10.79 to 10.97 mg/d L).Yeast cell wall based feed additive increased(P < 0.05)ADG(493 to 524 g/d),and ADFI(796 to 846 g/d)of pigs whereas G:F was not affected,and it also tended to increase(P=0.055)albumin level(3.46 to 3.63 g/d L).Interactions(P < 0.05)on hemoglobin,hematocrit,and platelet count indicated that YC further increased their levels when pigs were eating AF contaminated feed.Interactions(P < 0.05)on urea nitrogen and blood urea N to creatinine ratio indicated that YC further decreased their levels when feed were contaminated with AF.In conclusion,low level of 20 mg AF/kg under the regulatory level had minor effects on hematology without affecting growth performance,however the supplementation of 2 g/kg YC as a source ofβ-glucans and MOS in feed can improve feed intake and therefore the growth of pigs.展开更多
Subclinical necrotic enteritis(NE) causes devastating economic losses in the broiler chicken industry,especially in birds raised free of in-feed antibiotics. Prebiotics are potential alternatives to in-feed antibiotic...Subclinical necrotic enteritis(NE) causes devastating economic losses in the broiler chicken industry,especially in birds raised free of in-feed antibiotics. Prebiotics are potential alternatives to in-feed antibiotics. Yeast cell wall extract(YCW) derived from Saccharomyces cerevisiae is a prebiotic with known immune modulating effects. This study examined the effects of YCW and antibiotics(AB) during subclinical NE on broiler growth performance, intestinal lesions, humoral immune response and gut microflora metabolites. The study employed a 2 × 3 factorial arrangement of treatments. Factors were:NE challenge(yes or no) and feed additive(control, AB, or YCW). Each treatment was replicated in 8 floor pens with 15 birds per pen. Challenged birds had higher feed conversion ratio(FCR) than unchallenged birds on d 35(P < 0.05). Dietary inclusion of AB decreased FCR regardless of challenge(P < 0.05) on d 24 and 35. Inclusion of YCW reduced serum interleukin-1(IL-1) concentration in NE challenged birds(P < 0.01) and increased immunoglobulin(Ig) G(P < 0.05) and Ig M(P < 0.05) levels compared to other dietary treatments regardless of challenge. Yeast cell wall extract increased formic acid concentration in cecal contents during challenge and increased butyric acid concentration in unchallenged birds on d 16.This study indicates YCW suppressed inflammatory response, promoted generation of immunoglobulin and increased short chain fatty acid production suggesting potential benefits to bird health.展开更多
The purpose of this study was to investigate the potential benefits of yeast cell wall(YCW)on the gastrointestinal development of weaned calves.Twenty healthy Holstein male calves(BW=92±8.29 kg and 60±5 d of...The purpose of this study was to investigate the potential benefits of yeast cell wall(YCW)on the gastrointestinal development of weaned calves.Twenty healthy Holstein male calves(BW=92±8.29 kg and 60±5 d of age)were randomly allocated into 2 groups:CON with no YCW,and YCW(accounted for0.16%of the basal diet).The dietary concentrate-to-roughage ratio was 40:60.All the calves were fed regularly twice a day at 09:00 and 16:00 and had free access to water.The experiment lasted for 60 d.The results showed that calves fed YCW showed higher(P<0.05)length,width,and surface area of papillae in the ventral sac of the rumen as compared to CON.For the dorsal sac of the rumen,the muscularis thickness was thicker(P<0.05)in the YCW group when compared with CON group.The villus height of YCW calves was higher(P<0.05)than that of CON in the ileum.Calves supplemented with YCW also showed a higher(P<0.05)villus height-to-crypt depth ratio in the ileum.The YCW calves exhibited a greater(P<0.05)thickness of the wall in the duodenum and jejunum.Calves supplemented with YCW improved(P<0.05)the claudin 1 mRNA expression in the ileum and occludin mRNA expression in the jejunum and ileum.The YCW increased(P<0.05)the contents of secretory immunoglobulin A in the jejunum and ileum of calves.In conclusion,dietary supplementation with YCW could improve the gastrointestinal development of weaned calves.展开更多
基金Supported by Zhoushan Scientific and Technological Plan Program"Exploration of Net Hauler Safety Device for Fishing Trawler"(2016C32021)
文摘This study was conducted to determine the effects of yeast cell wall polysaccharides（YCWP） on reproductive performance, serum profiles and milk composition during late gestation and lactation. A total of 96 sows（Landrace × Yorkshire） were blocked on a basis of breed, parity（2-3）and their respective d 85 of gestation, and then randomly allotted to the following three dietary treatments： CON（basal diet, treatment 1）, YCWP1（CON＋0.2% YCWP, treatment 2） and YCWP2（CON＋0.4% YCWP, treatment 3）. The experiment lasted from d 85 of gestation to weaning（d 21 of lactation）. Sows fed YCWP diets had lower backfat thickness reduction from postpartum to weaning（ P〈0.05）. The supplementation of YCWP tended to increase litter weight at weaning（P=0.08） compared with CON. The non-lipid and total milk solids in colostrum was improved by YCWP2（P〈0.05）.No differences were observed in milk composition among dietary treatments（ P〉0.05）. The supplementation of YCWP decreased（P〈0.05） the levels of alanine amino transferase（ALT）, aspartate amino transferase（AST）, while it did not affect（ P〉0.05） alkaline phosphatase（ALP）, total protein（TP）,albumin（ALB）, globulin（GLB）, glucose（GLU）, total cholesterol（TC）, triglyceride（TG） or immunoglobulin G（IgG） in the sow serum. The serum IgG of piglets was increased by the YCWP. The levels of serum ALT and AST were reduced（P〈0.05） for suckling piglets in YCWP treatments. Taken together, the results of current studies might indicate beneficial effects of YCWP supplementation to late gestation and lactation diets on the sow productivity by improving litter weight at weaning, reducing backfat loss, and increasing serum IgG concentrations of piglets.
文摘This study was to investigate the effect of corn naturally contaminated with aflatoxins(AF)under the regulatory level on the growth performance and health of nursery pigs,and the efficiency of yeast cell wall based feed additive(YC)mainly composed ofβ-glucans and mannan oligosaccharide(MOS)(Integral A+,Alltech,Lexington,KY)in prevention of mycotoxicosis.Pigs(60 barrows and 60 gilts at 6.02 ± 0.83kg BW)were randomly allotted to 4 treatments in a randomized complete block design based on a 2×2 factorial arrangement with 10 pens(5 barrow and 5 gilt pens)per treatment and 3 pigs per pen.Pigs were fed experimental diets for 5 wk.First factor was AF(0 or 20 mg/kg in feed)and the second factor was YC(0 or 2 g/kg in feed).Feed intake and body weight were measured weekly,and blood samples were used to measure blood cell counts,immunoglobulin G(Ig G),tumor necrosis factor-a(TNF-a),oxidative damage status,and serological evaluation related to liver health.Aflatoxin decreased(P<0.05)the number of platelet count(247.4 to 193.5×10~3/μL),and it also tended to increase the level of albumin(P=0.055,3.46 to 3.63 g/d L),albumin:globulin ratio(P=0.050,2.09 to 2.37),and Ca(P=0.080,10.79 to 10.97 mg/d L).Yeast cell wall based feed additive increased(P < 0.05)ADG(493 to 524 g/d),and ADFI(796 to 846 g/d)of pigs whereas G:F was not affected,and it also tended to increase(P=0.055)albumin level(3.46 to 3.63 g/d L).Interactions(P < 0.05)on hemoglobin,hematocrit,and platelet count indicated that YC further increased their levels when pigs were eating AF contaminated feed.Interactions(P < 0.05)on urea nitrogen and blood urea N to creatinine ratio indicated that YC further decreased their levels when feed were contaminated with AF.In conclusion,low level of 20 mg AF/kg under the regulatory level had minor effects on hematology without affecting growth performance,however the supplementation of 2 g/kg YC as a source ofβ-glucans and MOS in feed can improve feed intake and therefore the growth of pigs.
基金Alltech (USA) is gratefully acknowledged for funding this project(13-E-9150)
文摘Subclinical necrotic enteritis(NE) causes devastating economic losses in the broiler chicken industry,especially in birds raised free of in-feed antibiotics. Prebiotics are potential alternatives to in-feed antibiotics. Yeast cell wall extract(YCW) derived from Saccharomyces cerevisiae is a prebiotic with known immune modulating effects. This study examined the effects of YCW and antibiotics(AB) during subclinical NE on broiler growth performance, intestinal lesions, humoral immune response and gut microflora metabolites. The study employed a 2 × 3 factorial arrangement of treatments. Factors were:NE challenge(yes or no) and feed additive(control, AB, or YCW). Each treatment was replicated in 8 floor pens with 15 birds per pen. Challenged birds had higher feed conversion ratio(FCR) than unchallenged birds on d 35(P < 0.05). Dietary inclusion of AB decreased FCR regardless of challenge(P < 0.05) on d 24 and 35. Inclusion of YCW reduced serum interleukin-1(IL-1) concentration in NE challenged birds(P < 0.01) and increased immunoglobulin(Ig) G(P < 0.05) and Ig M(P < 0.05) levels compared to other dietary treatments regardless of challenge. Yeast cell wall extract increased formic acid concentration in cecal contents during challenge and increased butyric acid concentration in unchallenged birds on d 16.This study indicates YCW suppressed inflammatory response, promoted generation of immunoglobulin and increased short chain fatty acid production suggesting potential benefits to bird health.
基金supported by the National Key Research and Development Program(no.2017YFD0502005)China Agriculture(Beef Cattle/Yak)Research System(CARS-37)
文摘The purpose of this study was to investigate the potential benefits of yeast cell wall(YCW)on the gastrointestinal development of weaned calves.Twenty healthy Holstein male calves(BW=92±8.29 kg and 60±5 d of age)were randomly allocated into 2 groups:CON with no YCW,and YCW(accounted for0.16%of the basal diet).The dietary concentrate-to-roughage ratio was 40:60.All the calves were fed regularly twice a day at 09:00 and 16:00 and had free access to water.The experiment lasted for 60 d.The results showed that calves fed YCW showed higher(P<0.05)length,width,and surface area of papillae in the ventral sac of the rumen as compared to CON.For the dorsal sac of the rumen,the muscularis thickness was thicker(P<0.05)in the YCW group when compared with CON group.The villus height of YCW calves was higher(P<0.05)than that of CON in the ileum.Calves supplemented with YCW also showed a higher(P<0.05)villus height-to-crypt depth ratio in the ileum.The YCW calves exhibited a greater(P<0.05)thickness of the wall in the duodenum and jejunum.Calves supplemented with YCW improved(P<0.05)the claudin 1 mRNA expression in the ileum and occludin mRNA expression in the jejunum and ileum.The YCW increased(P<0.05)the contents of secretory immunoglobulin A in the jejunum and ileum of calves.In conclusion,dietary supplementation with YCW could improve the gastrointestinal development of weaned calves.
