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Possibility of reaching the predicted center of the“island of stability”via the radioactive beam-induced fusion reactions
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作者 Ming-Hao Zhang Ying Zou +3 位作者 Mei-Chen Wang Gen Zhang Qing-Lin Niu Feng-Shou Zhang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第9期186-195,共10页
Based on the dinuclear system model,the synthesis of the predicted double-magic nuclei^(298)Fl and 304120 was investigated via neutron-rich radioactive beam-induced fusion reactions.The reaction^(58)Ca+^(244)Pu is pre... Based on the dinuclear system model,the synthesis of the predicted double-magic nuclei^(298)Fl and 304120 was investigated via neutron-rich radioactive beam-induced fusion reactions.The reaction^(58)Ca+^(244)Pu is predicted to be favorable for producing^(298)Fl with a maximal ER cross section of 0.301 pb.Investigations of the entrance channel effect reveal that the^(244)Pu target is more promising for synthesizing^(298)Fl than the neutron-rich targets^(248)Cm and^(249)Bk,because of the influence of the Coulomb barrier.For the synthesis of 304120,the maximal ER cross section of 0.046 fb emerges in the reaction^(58)V+^(249)Bk,indicating the need for further advancements in both experimental facilities and reaction mechanisms. 展开更多
关键词 Superheavy nuclei Dinuclear system model Fusion reaction Double-magic nucleus radioactive beam
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Effect of drying cracks on swelling and self-healing of bentonite-sand blocks used as engineered barriers for radioactive waste disposal
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作者 Yu Tan Guangping Zhou +2 位作者 Huyuan Zhang Xiaoya Li Ping Liu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第5期1776-1787,共12页
Experiments were conducted to evaluate the healing of drying cracks in air-dried bentonite-sand blocks after hydration and swelling in groundwater,providing justifications to simplify the protection of blocks prior to... Experiments were conducted to evaluate the healing of drying cracks in air-dried bentonite-sand blocks after hydration and swelling in groundwater,providing justifications to simplify the protection of blocks prior to installation in a high-level radioactive waste repository.Synthetic groundwater was prepared to represent the geochemistry of Beishan groundwater,and was used to hydrate the blocks during the swelling pressure and swelling strain measurements,as Beishan is the most promising site for China's repository.Healing of the surface cracks was recorded by photography,and healing of the internal cracks was visualized by CT images and hydraulic conductivity of air-dried blocks.The results indicate that the maximum swelling pressure and swelling strain are primarily affected by the geochemistry of Beishan groundwater,but not affected by the drying cracks.The maximum swelling pressure and swelling strain of air-dried blocks are comparable to or even higher than the pressure and strain of fresh blocks.The maximum swelling pressure measured in strong(i.e.high ion strength)Beishan groundwater was 44%of the pressure measured in deionized(DI)water,and the maximum swelling strain was reduced to 23%of the strain measured in DI water.Nevertheless,the remained swelling of the blocks hydrated in strong Beishan groundwater was sufficient to heal the surface and internal drying cracks,as demonstrated by the pictures of surface cracks and CT images.The hydraulic conductivity of the air-dried block permeated with strong groundwater was comparable(3.7×higher)to the hydraulic conductivity of the fresh block,indicating the self-healing of drying cracks after hydration and swelling in groundwater.A simplified method of protecting the block with plastic wraps before installation is recommended,since the remained swelling of the block hydrated in Beishan groundwater is sufficient to heal the drying cracks. 展开更多
关键词 Beishan groundwater chemistry Bentonite buffer Drying cracks High-level radioactive waste(HLW) SELF-HEALING SWELLING
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Prediction of Radioactive Half-Lives and Atomic Nucleus Dimensions in a Concentric Shell Model or Flocon Model
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作者 Marc Mignonat 《Journal of Modern Physics》 CAS 2022年第8期1216-1251,共36页
Considering only the wave aspect, we determine the energy of a bond between 2 nucleons;this quantified energy is associated with a standing wave. Then, starting from the mass loss corresponding to this energy, we dete... Considering only the wave aspect, we determine the energy of a bond between 2 nucleons;this quantified energy is associated with a standing wave. Then, starting from the mass loss corresponding to this energy, we determine the number of bonds in this nucleus. The mass defect value for a link is used to determine a specific length at that link. Fixing a precise distance between nucleons makes it possible to determine a geometry of the nucleus and its dimensions. It makes it possible to understand when this bond is stronger than the electrostatic force and allows deducing a shell model built in a precise order. The calculation on the mass defect will also make it possible to determine that one or more nucleons concerned by the radioactivity will be bound by a single bond to the rest of the nucleus or, on the contrary, bound by several bonds which induce short 1/2 lives or, on the contrary, very long. The analysis of the bonds on H, He and C make it possible to write formulae which are then applied to the nuclei to find the radioactive 1/2 lives. To find by equations the radioactive 1/2 lives does not call into question the standard model since it concerns only the defect of mass of the nuclei with energies that are not used to find the main particles of the standard model. This model, which favours a geometric approach to the detriment of a mathematical approach based on differential equations, can lead to theoretical questions about the possibility of interpreting the structure of the nucleus in a more undulatory way. It is possible to explain radioactivity in a more deterministic way. 展开更多
关键词 ½ radioactive lives Atomic Nucleus Dimensions Shell Model
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Application of radioactive iodine-125 microparticles in hepatocellular carcinoma with portal vein embolus
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作者 Peng Meng Ji-Peng Ma +1 位作者 Xiao-Fei Huang Kang-Le Zhang 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第7期2023-2030,共8页
BACKGROUND Radioactive iodine-125(125I)microparticle therapy is a new type of internal radiation therapy that has shown unique advantages in the treatment of malignant tumors,especially hepatocellular carcinoma.Patien... BACKGROUND Radioactive iodine-125(125I)microparticle therapy is a new type of internal radiation therapy that has shown unique advantages in the treatment of malignant tumors,especially hepatocellular carcinoma.Patients with hepatocellular carcinoma frequently experience portal vein embolism,which exacerbates the difficulty and complexity of treatment.125I particles,used in local radiotherapy,can directly act on tumor tissue and reduce damage to surrounding healthy tissue.Through retrospective analysis,this study discussed the efficacy and safety of radioactive 125I particles in portal vein embolization patients with hepatocellular carcinoma in order to provide more powerful evidence supporting clinical treatment.AIM To investigate the effect of transcatheter arterial chemoembolization combined with portal vein 125I particle implantation in the treatment of primary liver cancer patients with portal vein tumor thrombus and its influence on liver function.METHODS The clinical data of 96 patients with primary liver cancer combined with portal vein tumor thrombus admitted to our hospital between January 2020 and December 2023 were retrospectively analyzed.Fifty-two patients received treatment with transcatheter arterial chemoembolization and implantation of 125I particles in the portal vein(combination group),while 44 patients received treatment with transcatheter arterial chemoembolization alone(control group).The therapeutic effects on tumor lesions,primary liver cancer,and portal vein tumor embolisms were compared between the two groups.Changes in relevant laboratory indexes before and after treatment were evaluated.The t test was used to compare the measurement data between the two groups,and the χ^(2) test was used to compare the counting data between groups.RESULTS The tumor lesion response rate in the combination group(59.62%vs 38.64%)and the response rate of patients with primary liver cancer complicated with portal vein tumor thrombus(80.77%vs 59.09%)were significantly greater than those in the control group(χ^(2)=4.196,5.421;P=0.041,0.020).At 8 wk after surgery,the serum alpha-fetoprotein,portal vein main diameter,and platelet of the combined group were significantly lower than those of the control group,and the serum alanine aminotransferase,aspartate aminotransferase,and total bilirubin were significantly greater than those of the control group(t=3.891,3.291,2.330,3.729,3.582,4.126;P<0.05).The serum aspartate aminotransferase,alanine aminotransferase,and total bilirubin levels of the two groups were significantly greater than those of the same group 8 wk after surgery(P<0.05),and the peripheral blood platelet,alphafetoprotein,and main portal vein diameter were significantly less than those of the same group before surgery(P<0.05).CONCLUSION In patients with primary liver cancer and a thrombus in the portal vein,transcatheter arterial chemoembolization plus portal vein 125I implantation is more effective than transcatheter arterial chemoembolization alone.However,during treatment it is crucial to pay attention to liver function injury caused by transcatheter arterial chemoembolization. 展开更多
关键词 radioactive iodine-125 Hepatocellular carcinoma Transcatheter arterial chemoembolization Portal vein embolus Retrospective study
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Systematic study of proton radioactivity half‑lives
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作者 Yang‑Yang Xu Xiao‑Yuan Hu +3 位作者 De‑Xing Zhu Xi‑Jun Wu Peng‑Cheng Chu Xiao‑Hua Li 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第2期167-177,共11页
In the present study,on the basis of the screened electrostatic effect of the Coulomb potential,we propose an improved Gamow model within the centrifugal potential in which there are only two adjustable parameters,i.e... In the present study,on the basis of the screened electrostatic effect of the Coulomb potential,we propose an improved Gamow model within the centrifugal potential in which there are only two adjustable parameters,i.e.,the screened parameters t and g,which represent the combined effect of the interaction potential and reduced mass of the emitted proton-daughter nucleus on the half-life of proton radioactivity in the overlapping region.Using this model,we systematically calculated the proton radioactivity half-lives of 31 spherical nuclei and 13 deformed nuclei and obtained corresponding root-mean-square deviations of 0.274 and 0.367,respectively.The relationship between the proton radioactivity half-life of 177Tlm and the corresponding angular momentum l removed by the emitted proton is also discussed.In addition,we used the proposed model to predict the proton radioactivity half-lives of 18 nuclei whose proton radioactivity is energetically allowed or observed but not yet quantified in NUBASE2020.For comparison,we used the universal decay law of proton radioactivity proposed by Qi et al.(Phys Rev C 85:011303,2012.https://doi.org/10.1103/PhysR evC.85.011303),and the new Geiger–Nuttall law of proton radioactivity proposed by Chen et al.(Eur Phys J 55:214,2019.https://doi.org/10.1140/epja/i2019-12927-7). 展开更多
关键词 Proton radioactivity Gamow model HALF-lives
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越南非洲猪瘟疫苗AVAC ASF LIVE(ASFV-G-ΔMGF)研究工作分析与思考 被引量:1
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作者 戈胜强 沙洲 +5 位作者 左媛媛 初薛霏 徐天刚 张永强 李金明 王志亮 《中国动物检疫》 CAS 2024年第2期36-41,共6页
非洲猪瘟(Afcrian swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)感染引起的烈性传染病。近日,越南正式将经临床试验验证的非洲猪瘟弱毒疫苗AVAC ASF LIVE(ASFV-G-ΔMGF)在其全国推广使用。本文对越南非洲猪瘟弱... 非洲猪瘟(Afcrian swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)感染引起的烈性传染病。近日,越南正式将经临床试验验证的非洲猪瘟弱毒疫苗AVAC ASF LIVE(ASFV-G-ΔMGF)在其全国推广使用。本文对越南非洲猪瘟弱毒疫苗ASFV-G-ΔMGF相关研究数据进行了总结分析,分别从ASFVG-ΔMGF株攻毒保护能力评价、传代细胞培养株临床动物实验、野猪口服接种试验、毒力返强验证等方面,结合国内相关ASFV基因缺失株试验数据进行了分析。总结分析发现:越南上市的ASFV-G-ΔMGF疫苗株,二次免疫接种后攻毒保护效果更好,但在对野猪的口服接种评价中,其口鼻接种效果存在不确定性;随着疫苗株在动物体内的不断传代,其存在毒力返强和毒株变异风险,导致接种猪只临床症状明显;ASFV-G-ΔMGF株虽然有较好的攻毒保护能力和可靠的生产优势,但仍缺乏相关研究数据,特别是在垂直传播、交叉保护、基因突变等方面。后续仍需对ASFV-G-ΔMGF株的临床应用效果进一步评价。 展开更多
关键词 非洲猪瘟 减毒活疫苗 越南 ASFV-G-ΔMGF疫苗株
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基于LIVE2D技术的博物馆动态形象设计实践研究
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作者 宋美音 丁若钰 《设计》 2024年第17期144-148,共5页
探索以Live2D技术作为新的设计手段,进一步提升二维平面形象设计的表现力和影响力,寻找塑造新颖的博物馆动态形象的可行性,为博物馆提供适应现代多种媒体渠道传播形式的动态形象设计。以Live2D技术为核心,从文化传承与发展的角度出发,... 探索以Live2D技术作为新的设计手段,进一步提升二维平面形象设计的表现力和影响力,寻找塑造新颖的博物馆动态形象的可行性,为博物馆提供适应现代多种媒体渠道传播形式的动态形象设计。以Live2D技术为核心,从文化传承与发展的角度出发,结合博物馆实地调研与文物设计转化,拓宽博物馆形象设计在其馆内的应用范围,将传统平面原画通过2D建模,进而增强二维形象的可动性和真实感,结合符号学语义,实现以山东博物馆“亚丑钺”为例的动态形象设计实践。围绕博物馆藏品为原型,从平面设计图实现二维建模,实现文物藏品转化为角色形象,设计出基于Live2D技术的动态博物馆形象,为观展流程增添吸引力和沉浸感。促进博物馆以文物为原型的形象良性发展,丰富与观众的交互形式,帮助藏品达成创造性转化、创新性发展,从而为山东博物馆以及其他文化机构提供关于形象设计多元化创新的可借鉴新形式。 展开更多
关键词 live2D 二维建模 图像渲染技术 博物馆动态形象 动态视觉
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A novel method for gamma spectrum analysis of low-level and intermediate-level radioactive waste 被引量:2
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作者 Hui Yang Xin-Yu Zhang +4 位作者 Wei-Guo Gu Bing Dong Xue-Zhi Jiang Wen-Tao Zhou De-Zhong Wang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第6期199-213,共15页
The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral ... The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral analysis method is proposed in this study.In this method,overlapping peaks are located using a continuous wavelet transform.An improved quadratic convolution method is proposed to calculate the widths of the peaks and establish a fourth-order filter model to estimate the Compton edge baseline with the overlapping peaks.Combined with the adaptive sensitive nonlinear iterative peak,this method can effectively subtracts the background.Finally,a function describing the peak shape as a filter is used to deconvolve the energy spectrum to achieve accurate qualitative and quantitative analyses of the nuclide without the aid of a nuclide library.Gamma spectrum acquisition experiments for standard point sources of Cs-137 and Eu-152,a segmented gamma scanning experiment for a 200 L standard drum,and a Monte Carlo simulation experiment for triple overlapping peaks using the closest energy of three typical LILW nuclides(Sb-125,Sb-124,and Cs-134)are conducted.The results of the experiments indicate that(1)the novel method and gamma vision(GV)with an accurate nuclide library have the same spectral analysis capability,and the peak area calculation error is less than 4%;(2)compared with the GV,the analysis results of the novel method are more stable;(3)the novel method can be applied to the activity measurement of LILW,and the error of the activity reconstruction at the equivalent radius is 2.4%;and(4)The proposed novel method can quantitatively analyze all nuclides in LILW without a nuclide library.This novel method can improve the accuracy and precision of LILW measurements,provide key technical support for the reasonable disposal of LILW,and ensure the safety of humans and the environment. 展开更多
关键词 HPGe detector Low-level and intermediate-level radioactive waste Gamma spectrum analysis method Deconvolution method Continuous wavelet transform
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Short-term efficacy assessment of transarterial chemoembolization combined with radioactive iodine therapy in primary hepatocellular carcinoma 被引量:1
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作者 Lei Wang Kun Huang +6 位作者 Yu Zhang Yi-Fan Wu Zhen-Dong Yue Zhen-Hua Fan Fu-Quan Liu Yong-Wu Li Jian Dong 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第1期105-113,共9页
BACKGROUND Transarterial chemoembolization(TACE)is an effective treatment for primary hepatocellular carcinoma(PHC).Radioactive iodine therapy has been used in the treatment of advanced PHC,especially in patients with... BACKGROUND Transarterial chemoembolization(TACE)is an effective treatment for primary hepatocellular carcinoma(PHC).Radioactive iodine therapy has been used in the treatment of advanced PHC,especially in patients with portal vein tumor thrombosis.However,data on the therapeutic effect of TACE combined with radioactive iodine therapy in PHC are scarce.AIM To investigate the clinical efficacy of TACE combined with radioactive iodine implantation therapy in advanced PHC via perfusion computed tomography(CT).METHODS For this study,98 advanced PHC patients were recruited and divided randomly into the study and control groups.Patients in the study group were treated with TACE combined radioactive iodine implantation therapy.Patients in the control group were treated with only TACE.The tumor lesion length,clinical effect,serum alpha-fetoprotein(AFP)and CT perfusion parameters were compared before and after therapy,and statistical analysis was performed.RESULTS There was no significant difference in tumor length and serum AFP between the study and control groups(P>0.05)before treatment.However,the tumor length and serum AFP in the study group were lower than those in the control group 1 mo and 3 mo after therapy.After 3 mo of treatment,the complete and partial remission rate of the study group was 93.88%,which was significantly higher than the control group(77.55%)(P<0.05).Before treatment,there were no significant differences between the two groups on the perfusion CT variables,including the lesion blood volume,permeability surface,blood flow,hepatic artery flow and mean transit time(P>0.05).After 3 mo of treatment,all perfusion CT variables were lower in the study group compared to the control group(P<0.05).The survival time of patients in the study group was 22 mo compared to 18 mo in the control group,which was significantly different[log rank(Mantel-Cox)=4.318,P=0.038].CONCLUSION TACE combined with radioactive iodine implantation in the treatment of advanced PHC can inhibit the formation of blood vessels in tumor tissue and reduce the perfusion level of tumor lesions,thereby improving the clinical efficacy and prolonging the survival time of patients. 展开更多
关键词 Transarterial chemoembolization radioactive iodine Primary hepatocellular carcinoma PERFUSION Computed tomography
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Liver transplantation and resection in patients with hepatocellular cancer and portal vein tumor thrombosis: Feasible and effective? 被引量:3
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作者 Prashant Bhangui 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第2期123-128,共6页
Patients with locally advanced hepatocellular cancer(HCC)and portal vein tumor thrombosis(PVTT)have a dismal prognosis since limited treatment options are available for them.In recent years,effective systemic therapy,... Patients with locally advanced hepatocellular cancer(HCC)and portal vein tumor thrombosis(PVTT)have a dismal prognosis since limited treatment options are available for them.In recent years,effective systemic therapy,and advances in the understanding of technicalities and effectiveness of ablative therapies especially radiotherapy,have given some hope to prolong survival in them.This review summarized recent evidence in literature regarding the possible role of liver resection(LR)and liver transplantation(LT)in patients with locally advanced HCC and PVTT with no extrahepatic disease.Downstaging therapies have helped make curative resection or LT a reality in selected patients.This review emphasizes on the key points to focus on when considering surgery in these patients,who are usually relegated to palliative systemic therapy alone.Meticulous patient selection based on tumor biology,documented downstaging based on imaging and decrease in tumor marker levels,and an adequate waiting period to demonstrate stable disease,may help obtain satisfactory long-term outcomes post LR or LT in an intention to treat strategy in patients with HCC and PVTT. 展开更多
关键词 Hepatocellular carcinoma Portal vein tumour thrombosis Downstaging therapies Living donor liver transplantation and resection OUTCOMES
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Relationship between Whole Body Iodine-131 Effective Half-Life and Estimated Glomerular Filtration Rate for Papillary Thyroid Cancer Patients Undergoing Radioactive Iodine Therapy
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作者 Asim Abualnaja Hanaa Alsheikh +2 位作者 Khaled Soliman Meshal Alnefaie Abdulraheem Alsheri 《Journal of Applied Mathematics and Physics》 2023年第8期2472-2479,共8页
Background: The aim of this work was to examine the relationship between the estimated glomerular filtration rate (eGFR) as indicator of renal efficiency potentially related to the ability to release radioactive iodin... Background: The aim of this work was to examine the relationship between the estimated glomerular filtration rate (eGFR) as indicator of renal efficiency potentially related to the ability to release radioactive iodine from the patients bodies and the radioactive iodine whole body effective half-life (WBEHL) defined as the time taken for the administered activity to decay to half of its value for papillary thyroid cancer (PTC) patients undergoing radioactive iodine therapy (RAIT) in a tertiary care medical Centre. Methods: This retrospective observational study included seventy nine patients, sixty females and nineteen males. The patients were divided in two subgroups, those who have WBEHL of less than 11 hours (n = 51) and those with more than 11 (n = 28) hrs based on k-means clustering technique. Results: Analysis of variance (ANOVA) was used to find out if there is a statistically significant difference between the two subgroups Conclusion: There was not a statistically significant difference between the short and the longer WBEHL patients’ groups analyzed in this study. . 展开更多
关键词 GFR Thyroid Cancer radioactive Iodine Therapy Renal Function
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Radioactive 125I seed implantation for pancreatic cancer with unexpected liver metastasis:A preliminary experience with 26 patients 被引量:4
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作者 Cheng-Gang Li Zhi-Peng Zhou +2 位作者 Yu-Ze Jia Xiang-Long Tan Yu-Yao Song 《World Journal of Clinical Cases》 SCIE 2021年第4期792-800,共9页
BACKGROUND Preoperative diagnosis rate of pancreatic cancer has increased year by year.The prognosis of pancreatic cancer patients with unexpected liver metastasis found by intraoperative exploration is very poor,and ... BACKGROUND Preoperative diagnosis rate of pancreatic cancer has increased year by year.The prognosis of pancreatic cancer patients with unexpected liver metastasis found by intraoperative exploration is very poor,and there is no effective and unified treatment strategy.AIM To evaluate the therapeutic effect of radioactive 125I seed implantation for pancreatic cancer patients with unexpected liver metastasis.METHODS The demographics and perioperative outcomes of patients who underwent 125I seed implantation to treat pancreatic cancer with unexpected liver metastasis between January 1,2017 and June 1,2019 were retrospectively analyzed.During the operation,125I seeds were implanted into the pancreatic tumor under the guidance of intraoperative ultrasound,with a spacing of 1.5 cm and a row spacing of 1.5 cm.For patients with obstructive jaundice and digestive tract obstruction,choledochojejunostomy and gastroenterostomy were performed simultaneously.After operation,the patients were divided into a non-chemotherapy group and a chemotherapy group that received gemcitabine combined with albumin-bound paclitaxel treatment.RESULTS Preoperative imaging evaluation of all patients in this study showed that the tumor was resectable without liver metastasis.There were 26 patients in this study,including 18 males and 8 females,aged 60.5±9.7 years.The most common tumor site was the pancreatic head(17,65.4%),followed by the pancreatic neck and body(6,23.2%)and pancreatic tail(3,11.4%).Fourteen patients(53.8%)underwent palliative surgery and postoperative pain relief occurred in 22 patients(84.6%).The estimated blood loss in operation was 148.3±282.1 mL and one patient received blood transfusion.The postoperative hospital stay was 7.6±2.8 d.One patient had biliary fistula,one had pancreatic fistula,and all recovered after conservative treatment.After operation,7 patients received chemotherapy and 19 did not.The 1-year survival rate was significantly higher in patients who received chemotherapy than in those who did not(68.6%vs 15.8%,P=0.012).The mean overall survival of patients in the chemotherapy group and non-chemotherapy group was 16.3 mo and 10 mo,respectively(χ2=7.083,P=0.008).CONCLUSION Radioactive 125I seed implantation combined with postoperative chemotherapy can prolong the survival time and relieve pain of pancreatic cancer patients with unexpected liver metastasis. 展开更多
关键词 Pancreatic cancer liver metastases radioactive 125I seeds RADIOTHERAPY Permanent implantation Therapeutic effect
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Analysis of Morphometric Parameters and Radioactive Characteristics Using Remote Sensing Data and GIS Techniques in the Wadi Wizr Basin Area, Central Eastern Desert, Egypt
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作者 Sameh Anwar Ibrahim Hammouda Soliman Abu Elatta A. Mahmoud 《Journal of Geoscience and Environment Protection》 2023年第6期197-219,共23页
The purpose of this study is to demonstrate how modern technologies such as geographic information systems (GIS) and digital elevation models can help in the creation of a geographic database for the Wadi Wizr basin i... The purpose of this study is to demonstrate how modern technologies such as geographic information systems (GIS) and digital elevation models can help in the creation of a geographic database for the Wadi Wizr basin in Egypt’s Central Eastern Desert, in addition to examining and analysing the radioactive properties of various rocks. This was accomplished with the help of a digital elevation model (DEM) with a 30 metre accuracy and GIS software in 10.8 Arc Map. The RS-230 was also used to measure uranium and thorium concentrations. GIS softwares and digital elevation models have been shown to be more effective than the traditional method. This was demonstrated by the flexible and quick working method, the accuracy of the parameters used, and the results of the morphometric analysis of the basin river network. In addition to, the main drainage pattern from subtype to tree type, where the branching ratio was (1.59). This basin could also cause flooding. Similar studies, according to the results of this study, should make greater use of geographic information system technology and modern data sources. Wadi Wizr also has a radioactive anomaly, with uranium equivalent concentrations reaching 70 ppm in some fault parts. 展开更多
关键词 Wadi Wizr Basin Morphometric Analysis Drainage Pattern radioactive Characteristics Remote Sensing Geographic Information System
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Establishing delivery route-dependent safety and efficacy of living biodrug mesenchymal stem cells in heart failure patients 被引量:1
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作者 Muhammad Candragupta Jihwaprani Idris Sula +1 位作者 Mohamed Ahmed Charbat Khawaja Husnain Haider 《World Journal of Cardiology》 2024年第6期339-354,共16页
BACKGROUND Mesenchymal stem cells(MSCs)as living biopharmaceuticals with unique properties,i.e.,stemness,viability,phenotypes,paracrine activity,etc.,need to be administered such that they reach the target site,mainta... BACKGROUND Mesenchymal stem cells(MSCs)as living biopharmaceuticals with unique properties,i.e.,stemness,viability,phenotypes,paracrine activity,etc.,need to be administered such that they reach the target site,maintaining these properties unchanged and are retained at the injury site to participate in the repair process.Route of delivery(RoD)remains one of the critical determinants of safety and efficacy.This study elucidates the safety and effectiveness of different RoDs of MSC treatment in heart failure(HF)based on phase II randomized clinical trials(RCTs).We hypothesize that the RoD modulates the safety and efficacy of MSCbased therapy and determines the outcome of the intervention.AIM To investigate the effect of RoD of MSCs on safety and efficacy in HF patients.METHODS RCTs were retrieved from six databases.Safety endpoints included mortality and serious adverse events(SAEs),while efficacy outcomes encompassed changes in left ventricular ejection fraction(LVEF),6-minute walk distance(6MWD),and pro-B-type natriuretic peptide(pro-BNP).Subgroup analyses on RoD were performed for all study endpoints.RESULTS Twelve RCTs were included.Overall,MSC therapy demonstrated a significant decrease in mortality[relative risk(RR):0.55,95%confidence interval(95%CI):0.33-0.92,P=0.02]compared to control,while SAE outcomes showed no significant difference(RR:0.84,95%CI:0.66-1.05,P=0.11).RoD subgroup analysis revealed a significant difference in SAE among the transendocardial(TESI)injection subgroup(RR=0.71,95%CI:0.54-0.95,P=0.04).The pooled weighted mean difference(WMD)demonstrated an overall significant improvement of LVEF by 2.44%(WMD:2.44%,95%CI:0.80-4.29,P value≤0.001),with only intracoronary(IC)subgroup showing significant improvement(WMD:7.26%,95%CI:5.61-8.92,P≤0.001).Furthermore,the IC delivery route significantly improved 6MWD by 115 m(WMD=114.99 m,95%CI:91.48-138.50),respectively.In biochemical efficacy outcomes,only the IC subgroup showed a significant reduction in pro-BNP by-860.64 pg/mL(WMD:-860.64 pg/Ml,95%CI:-944.02 to-777.26,P=0.001).CONCLUSION Our study concluded that all delivery methods of MSC-based therapy are safe.Despite the overall benefits in efficacy,the TESI and IC routes provided better outcomes than other methods.Larger-scale trials are warranted before implementing MSC-based therapy in routine clinical practice. 展开更多
关键词 Clinical trial Heart failure Mesenchymal stem cells Living biodrug META-ANALYSIS Stem cells Systematic review
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Heuristic techniques for maximum likelihood localization of radioactive sources via a sensor network
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作者 Assem Abdelhakim 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第8期174-193,共20页
Maximum likelihood estimation(MLE)is an effective method for localizing radioactive sources in a given area.However,it requires an exhaustive search for parameter estimation,which is time-consuming.In this study,heuri... Maximum likelihood estimation(MLE)is an effective method for localizing radioactive sources in a given area.However,it requires an exhaustive search for parameter estimation,which is time-consuming.In this study,heuristic techniques were employed to search for radiation source parameters that provide the maximum likelihood by using a network of sensors.Hence,the time consumption of MLE would be effectively reduced.First,the radiation source was detected using the k-sigma method.Subsequently,the MLE was applied for parameter estimation using the readings and positions of the detectors that have detected the radiation source.A comparative study was performed in which the estimation accuracy and time consump-tion of the MLE were evaluated for traditional methods and heuristic techniques.The traditional MLE was performed via a grid search method using fixed and multiple resolutions.Additionally,four commonly used heuristic algorithms were applied:the firefly algorithm(FFA),particle swarm optimization(PSO),ant colony optimization(ACO),and artificial bee colony(ABC).The experiment was conducted using real data collected by the Low Scatter Irradiator facility at the Savannah River National Laboratory as part of the Intelligent Radiation Sensing System program.The comparative study showed that the estimation time was 3.27 s using fixed resolution MLE and 0.59 s using multi-resolution MLE.The time consumption for the heuristic-based MLE was 0.75,0.03,0.02,and 0.059 s for FFA,PSO,ACO,and ABC,respectively.The location estimation error was approximately 0.4 m using either the grid search-based MLE or the heuristic-based MLE.Hence,heuristic-based MLE can provide comparable estimation accuracy through a less time-consuming process than traditional MLE. 展开更多
关键词 radioactive source Maximum likelihood estimation Multi-resolution MLE k-sigma Firefly algorithm Particle swarm optimization Ant colony optimization Artificial bee colony
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Rapid progression of heart failure secondary to radioactive iodine treatment of hyperthyroidism:A case report
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作者 Zi-Han Li Lu-Jia Ni +1 位作者 Yuan-Qiao Liu Dao-Yuan Si 《World Journal of Clinical Cases》 SCIE 2023年第22期5316-5321,共6页
BACKGROUND The deterioration of thyroid health is involved in the progression of heart failure(HF).This is usually a lengthy process,so there are almost no reports on its rapid development.Here we report a case of a y... BACKGROUND The deterioration of thyroid health is involved in the progression of heart failure(HF).This is usually a lengthy process,so there are almost no reports on its rapid development.Here we report a case of a young male who rapidly developed hypothyroid cardiomyopathy secondary to radioactive iodine treatment,suggesting that severe HF might occur even after a short period of hypothyroidism.CASE SUMMARY A 26-year-old man was referred to our hospital for HF presenting with dyspnea on exertion and chest discomfort lasting for 1 mo.He received radioactive iodine treatment for hyperthyroidism 1 year ago and had an almost normal echocardiogram 6 mo ago.Admission echocardiogram and cardiac magnetic resonance(CMR)revealed left ventricle(LV)global hypokinesia and severely depressed systolic function.In addition,late gadolinium enhancement indicated no obvious changes in the myocardium.Thyroid function tests showed decreased serum levels of thyroid hormone(TH)and elevated thyroid-stimulating hormone.Based on an exclusionary examination,the patient was diagnosed with hypothyroid cardiomyopathy and was started on replacement therapy.His HF symptoms were completely relieved during the six-month follow-up,and echocardiogram and CMR revealed recovered LV size and ejection fraction.CONCLUSION This report demonstrates that severe fluctuations in TH levels may lead to acute HF,which can completely recover with timely thyroid hormone replacement.In addition,our findings highlight the importance of routinely detecting cardiac function in patients treated with radioactive iodine. 展开更多
关键词 Heart failure Hypothyroid cardiomyopathy Hormone replacement therapy radioactive iodine therapy Case report
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Xiao-Ping Chen:the“Master of the Scalpel”who saves lives by entering the forbidden territory of hepatopancreatobiliary surgery
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作者 Editorial Office of Oncology and Translational Medicine 《Oncology and Translational Medicine》 2023年第6期239-240,共2页
In his 50 years of practice,he has performed more than 20,000 hepatopancreatobiliary surgeries,being the first one to propose the concept of the“auxiliary partial orthotopic liver transplantation”internationally.Fur... In his 50 years of practice,he has performed more than 20,000 hepatopancreatobiliary surgeries,being the first one to propose the concept of the“auxiliary partial orthotopic liver transplantation”internationally.Furthermore,he developed the“Chen's inserting biliary-enteric anastomosis and pancreato-enteric anastomosis,”“Chen's hepatic vascular occlusion,”“Chen's liver double-hanging maneuver,”and“Chen's hepatic vascular occlusion without liver portal dissection.”He also popularized these theories and techniques both in China and worldwide.His name is Xiao-Ping Chen,an academician of the Chinese Academy of Sciences and honorary president of the Tongji Medical College of Huazhong University of Science and Technology. 展开更多
关键词 hepato BILIARY lives
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Systematic study on heavy-particle radioactivity of superheavy nuclei ^(297–300)119
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作者 Megha Chandran V.K.Anjali K.P.Santhosh 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第11期108-123,共16页
In the current study,we examined every possible cluster-daughter combination in the heavy-particle decay of isotopes ^(297-300)119 and computed the decay half-lives using the modified generalized liquid drop model(MGL... In the current study,we examined every possible cluster-daughter combination in the heavy-particle decay of isotopes ^(297-300)119 and computed the decay half-lives using the modified generalized liquid drop model(MGLDM)with the preformation factor depending on the disintegration energy.The predicted half-life of every heavy cluster(Z_(C)≥32)was within the experimentally observable limits.These results aligned with the predictions of Poenaru et al.[Phys.Rev.Lett.107,062503(2011)]that superheavy nuclei(SHN)with Z>110 will release heavy particles with a penetrability comparable to or greater than theα-decay.The half-lives predicted using the MGLDM for clusters^(89)Rb,^(91)Rb,and^(92)Rb from parents^(297)119,^(299)119,and^(300)119,respectively,agreed with the predictions of Poenaru et al.[Eur.Phys.J.A 54,14(2018)].It was found that the isotopes of heavy clusters Kr,Rb,Sr,Pa,In,and Cd had half-lives comparable to theαhalf-life;and isotopes of clusters I,Xe,and Cs had the minimum half-life(10^(-14)s).These observations revealed the role of the shell closure(Z=82,N=82,and N=126)of the cluster and daughter nuclei in heavy-cluster radioactivity.We predicted that isotope ^(297,299)119 decayed by 4αdecay chains and isotope^(300)119 decayed by 6αdecay chains,while^(298)119 decayed by continuousαdecay chains.The predicted half-lives and modes of decay of the nuclei in the decay chains of^(297-300)119 agreed with the experimental data,proving the reliability of our calculations.The present study determined the most favorable heavy-cluster emissions from these nuclei and provided suitable projectile-target combinations for their synthesis. 展开更多
关键词 Cluster radioactivity Alpha radioactivity Superheavy nuclei
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Significance of Live Streaming in Shaping Business: A Critical Review and Analytical Study
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作者 Nasir Uddin 《Social Networking》 2024年第3期35-43,共9页
With the rise of live streaming on social media, platforms like Facebook, Instagram, and YouTube have become powerful business tools. They enable users to share live videos, fostering direct connections between busine... With the rise of live streaming on social media, platforms like Facebook, Instagram, and YouTube have become powerful business tools. They enable users to share live videos, fostering direct connections between businesses and their customers. This critical literature review paper explores the impact of live streaming on businesses, focusing on its role in attracting and satisfying consumers by promoting products tailored to their needs and wants. It emphasizes live streaming’s crucial role in engaging customers, a key to business growth. The study also provides viable strategies for businesses to leverage live streaming for growth and customer engagement, underscoring its importance in the business landscape. 展开更多
关键词 live Streaming Social Media Business Impact Consumer Decision-Making Brand Community Interactive Marketing Facebook live Instagram live Product Reviews Online Consumer Behavior Self-Determination Theory (SDT) live Video Marketing
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Changing Lives
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《ChinAfrica》 2023年第10期24-26,共3页
Implementation of the BRI projects has heralded positive changes in the lives of Tanzanian people Tanzania is an important Belt and Road Initiative(BRI)hub in Africa.It signed a BRI cooperation memorandum with China i... Implementation of the BRI projects has heralded positive changes in the lives of Tanzanian people Tanzania is an important Belt and Road Initiative(BRI)hub in Africa.It signed a BRI cooperation memorandum with China in 2018.Bilateral exchanges have been on the rise since then.On the occasion of the 10th anniversary of the launch of the initiative,ChinAfrica sat down with Mbelwa Kairuki,Tanzanian ambassador to China,to hear his insights on the BRI,especially the changes brought by the BRI to the local people’s lives. 展开更多
关键词 AFRICA lives CHANGING
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