Naipaul＇s novel A bend in the river illustrates the social confusion and people＇s destitution and wasting time in African countries after their national independence. An important reason is the president＇s self-pub...Naipaul＇s novel A bend in the river illustrates the social confusion and people＇s destitution and wasting time in African countries after their national independence. An important reason is the president＇s self-publicity, tyrannical hess and destructiveness. Whereas the author＇s subjective suspicion is visible in democratic development of African countries. Indeed, in a country development, it is quite necessary to depend on its citizen, observing public feelings; controlling a state with science; benefiting citizen; utilizing resources; constructing homestead, intending creation with a harmonious and stable way.展开更多
With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And th...With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And the analysis on the virus affinity peptide with high selectivity and high sensitivity could provide valuable means for disease detection, treatment as wel as the study on the molecular mechanism of virus affinity peptide. Therefore, we reviewed the bioinformatics pre-diction technologies of computer simulation, molecular docking and homology model-ing, as wel as the research method on analyzing and screening virus affinity pep-tide, such as Phage display technology.展开更多
AIM To evaluate the numbers of different subsets of monocytes and their associations with the values of clinical measures in mild acute pancreatitis(MAP) patients.METHODS The study included one group of 13 healthy con...AIM To evaluate the numbers of different subsets of monocytes and their associations with the values of clinical measures in mild acute pancreatitis(MAP) patients.METHODS The study included one group of 13 healthy controls and another group of 24 patients with new-onset MAP. The numbers of different subsets of monocytes were examined in these two groups of subjects by flow cytometry. The concentrations of plasma interleukin(IL)-10 and IL-12 were determined by cytometric bead array. The acute physiology and chronic health evaluation(APACHE) II scores of individual patients were evaluated, and the levels of plasma C-reactive protein(CRP) as well as the activities of amylase and lipase were measured. RESULTS In comparison with that in the controls, significantly increased numbers of CD14+CD163-, CD14+CD163-MAC387+ M1 monocytes, but significantly reduced numbers of CD14+CD163+IL-10+ M2 monocytes were detected in the MAP patients(P < 0.01 or P < 0.05). Furthermore, significantly higher levels of plasma IL-10 and IL-12 were observed in the MAP patients(P < 0.01 for all). More importantly, the levels of plasma CRP were positively correlated with the numbers of CD14+CD163-(R = 0.5009, P = 0.0127) and CD14+CD163-MAC387+(R = 0.5079, P = 0.0113) M1 monocytes and CD14+CD163+CD115+ M2 monocytes(R = 0.4565, P = 0.0249) in the patients. The APACHE II scores correlated with the numbers of CD14+CD163+CD115+(R = 0.4581, P = 0.0244) monocytes and the levels of plasma IL-10(R = 0.4178, P = 0.0422) in the MAP patients. However, there was no significant association among other measures tested in this population. CONCLUSION Increased numbers of CD14+CD163- and CD14+ CD163-MAC387+ monocytes may contribute to the pathogenesis of MAP, and increased numbers of CD14+CD163+CD115+ monocytes may be a biomarker for evaluating the severity of MAP.展开更多
A society of knowledge has a mission based on information dissemination and its usage, but its purpose cannot be completely realized without library as an institution that collects, processes, archives, protects and p...A society of knowledge has a mission based on information dissemination and its usage, but its purpose cannot be completely realized without library as an institution that collects, processes, archives, protects and provides library collections to the public. Elementary- and high-school libraries, as well as the academic ones, are ubiquitous as associates and promoters of importance of information in the Digital Age. Information literacy becomes a foundation of an individual＇s literacy in general and leads him/her toward lifelong learning that becomes a philosophy on the way to a society of knowledge. The paper presents research results of informatics and information literacy among students with a purpose of improving the library mission and vision within future education. Data were collected by poll and the pollees were high-school and university students of Slavonski Brod and Osijek. This study found that although the trend of Internet usage in a library is not high, the percentage of those possessing a basic Information and Communication Technology OCT） literacy level is high. Another significant fact is that the number of those unskilled in ICT usage （online database and catalog search） is high which represents a challenge to the libraries and ICT experts who are the incumbents of great responsibility.展开更多
We have adapted and characterized electrolysis reactors to complement the conversion of regional- and community-scale quantities of waste into fuel or chemicals, The overall process must he able to contend with a wide...We have adapted and characterized electrolysis reactors to complement the conversion of regional- and community-scale quantities of waste into fuel or chemicals, The overall process must he able to contend with a wide range of feedstocks, must he inherently safe, and should not rely on external facilities for co-reactants or heat rejection and supply, Our current approach is based on the upgrading of hio-oil produced by the hydrothermal liquefaction （HTL） of carbon-containing waste feedstocks, HTL can convert a variety of feedstocks into a bio-oil that requires much less upgrading than the products of other ways of deconstructing hiomass, We are now investigating the use of electrochemical processes for the further conversions needed to transform the hio-oil from HTL into fuel or higher value chemicals, We, and others, have shown that electrochemical reduction can offer adequate reaction rates and at least some of the nec- essary generality, In addition, an electrochemical reactor necessarily both oxidizes （removes electrons） on one side of the reactor and reduces （adds electrons） on the other side, Therefore, the two types of reac- tions could, in principle, he coupled to upgrade the hio-oil and simultaneously polish the water that is employed as a reactant and a carrier in the upstream HTL, Here, we overview a notional process, the possible conversion chemistry, and the economics of an HTL-electrochemical process,展开更多
AIM:To study the effect of circulating cell-free oxy-hemoglobin(FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS:To induce elevated intravascular circulating FHb,male Spragu...AIM:To study the effect of circulating cell-free oxy-hemoglobin(FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS:To induce elevated intravascular circulating FHb,male Sprague-Dawley rats received water or FHb infusion.Microcirculatory changes in jejunum,ileum and colon were evaluated using fluorescent microspheres.Intestinal injury was quantified as plasmatic release of ileal lipid binding protein(iLBP) and verified by histological analysis of the ileum. RESULTS:Water and FHb infusions resulted,when compared with saline infusion,in reduced intestinal microcirculation(after 30 min P<0.05,or better;after 60 min FHb infusion P<0.05 for jejunum and colon) .Circulating FHb levels correlated significantly with release of iLBP(Spearman r=0.72,P=0.0011) .Epithelial cell injury of the villi was histologically observed after water and FHb infusions. CONCLUSION:This study shows that circulating FHb leads to a reduction in intestinal microcirculatory blood flow with marked injury to intestinal epithelial cells. These data support the hypothesis that circulating FHb contributes to the development of intestinal injury.展开更多
Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper inten...Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper intends to fill this vacuum. It seeks to rediscover Epstein＇s communist experience, with particular focus on his fervent activism in and unapologetic defense of the Cultural Revolution. Through analyzing his experience, this paper exposes the essential allurement of Chinese communism encapsulated in the ideals of revolutionary regeneration and revolutionary virtues. Beyond Epstein＇s communist experience, this paper calls for a deeper and broader pondering on the analogy between communism and religion. Such an illuminating analogy should inspire more intellectual efforts than critical expositions of formalistic vainglory or personality cult.展开更多
The 7th Biennial Conference of Chinese Ecological Economics Society (CEES) was held from 5th to 7th, Nov.2006 in Qingdao University. The paper summarizes the major viewpoint presented at the conference: eco-economicre...The 7th Biennial Conference of Chinese Ecological Economics Society (CEES) was held from 5th to 7th, Nov.2006 in Qingdao University. The paper summarizes the major viewpoint presented at the conference: eco-economicresearch and construction of a harmonious society in China. The conference put forward that it is an objectivity andinevitability for human being to enter the harmonious society, that eco-economics is one of the theoretical bases for theconstruction of the harmonious society, and that the research of eco-economics in China should reflect new contentsdeveloped in the process of modernization in China and make proper contributions to the construction of the harmonioussociety.展开更多
We describe a patient with a Homo sapiens mutL homolog 1 (MLH1)-associated Lynch syndrome with previous diagnoses of two distinct primary cancers:a sigmoid colon cancer at the age of 39 years, and a right colon cancer...We describe a patient with a Homo sapiens mutL homolog 1 (MLH1)-associated Lynch syndrome with previous diagnoses of two distinct primary cancers:a sigmoid colon cancer at the age of 39 years, and a right colon cancer at the age of 50 years. The mutation identified in his blood and buccal cells, c.1771delG, p.Asp591Ilefs*25, appears to be a de novo event, as it was not transmitted by either of his parents. This type of de novo event is rare in MLH1 as only three cases have been reported in the literature so far. Further-more, the discordant results observed between repli-cation error phenotyping and immunohistochemistry highlight the importance of the systematic use of both pre-screening tests in the molecular diagnosis of Lynch syndrome.展开更多
The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a h...The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a harmonious relationship between teachers and students, the positions of the teachers and students in teaching should be first made clear, and then an effective mental communication between teachers and students is necessarily available.展开更多
文摘Naipaul＇s novel A bend in the river illustrates the social confusion and people＇s destitution and wasting time in African countries after their national independence. An important reason is the president＇s self-publicity, tyrannical hess and destructiveness. Whereas the author＇s subjective suspicion is visible in democratic development of African countries. Indeed, in a country development, it is quite necessary to depend on its citizen, observing public feelings; controlling a state with science; benefiting citizen; utilizing resources; constructing homestead, intending creation with a harmonious and stable way.
基金Supported by the Key Science and Technology Program of Henan Province(162102110136)the Science and Technology Fund for Outstanding Young People of Henan Academy of Agricultural Sciences(2016YQ28)~~
文摘With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And the analysis on the virus affinity peptide with high selectivity and high sensitivity could provide valuable means for disease detection, treatment as wel as the study on the molecular mechanism of virus affinity peptide. Therefore, we reviewed the bioinformatics pre-diction technologies of computer simulation, molecular docking and homology model-ing, as wel as the research method on analyzing and screening virus affinity pep-tide, such as Phage display technology.
文摘AIM To evaluate the numbers of different subsets of monocytes and their associations with the values of clinical measures in mild acute pancreatitis(MAP) patients.METHODS The study included one group of 13 healthy controls and another group of 24 patients with new-onset MAP. The numbers of different subsets of monocytes were examined in these two groups of subjects by flow cytometry. The concentrations of plasma interleukin(IL)-10 and IL-12 were determined by cytometric bead array. The acute physiology and chronic health evaluation(APACHE) II scores of individual patients were evaluated, and the levels of plasma C-reactive protein(CRP) as well as the activities of amylase and lipase were measured. RESULTS In comparison with that in the controls, significantly increased numbers of CD14+CD163-, CD14+CD163-MAC387+ M1 monocytes, but significantly reduced numbers of CD14+CD163+IL-10+ M2 monocytes were detected in the MAP patients(P < 0.01 or P < 0.05). Furthermore, significantly higher levels of plasma IL-10 and IL-12 were observed in the MAP patients(P < 0.01 for all). More importantly, the levels of plasma CRP were positively correlated with the numbers of CD14+CD163-(R = 0.5009, P = 0.0127) and CD14+CD163-MAC387+(R = 0.5079, P = 0.0113) M1 monocytes and CD14+CD163+CD115+ M2 monocytes(R = 0.4565, P = 0.0249) in the patients. The APACHE II scores correlated with the numbers of CD14+CD163+CD115+(R = 0.4581, P = 0.0244) monocytes and the levels of plasma IL-10(R = 0.4178, P = 0.0422) in the MAP patients. However, there was no significant association among other measures tested in this population. CONCLUSION Increased numbers of CD14+CD163- and CD14+ CD163-MAC387+ monocytes may contribute to the pathogenesis of MAP, and increased numbers of CD14+CD163+CD115+ monocytes may be a biomarker for evaluating the severity of MAP.
文摘A society of knowledge has a mission based on information dissemination and its usage, but its purpose cannot be completely realized without library as an institution that collects, processes, archives, protects and provides library collections to the public. Elementary- and high-school libraries, as well as the academic ones, are ubiquitous as associates and promoters of importance of information in the Digital Age. Information literacy becomes a foundation of an individual＇s literacy in general and leads him/her toward lifelong learning that becomes a philosophy on the way to a society of knowledge. The paper presents research results of informatics and information literacy among students with a purpose of improving the library mission and vision within future education. Data were collected by poll and the pollees were high-school and university students of Slavonski Brod and Osijek. This study found that although the trend of Internet usage in a library is not high, the percentage of those possessing a basic Information and Communication Technology OCT） literacy level is high. Another significant fact is that the number of those unskilled in ICT usage （online database and catalog search） is high which represents a challenge to the libraries and ICT experts who are the incumbents of great responsibility.
基金supported by the Laboratory Directed Research & Development program at Pacific Northwest National Laboratory (PNNL)
文摘We have adapted and characterized electrolysis reactors to complement the conversion of regional- and community-scale quantities of waste into fuel or chemicals, The overall process must he able to contend with a wide range of feedstocks, must he inherently safe, and should not rely on external facilities for co-reactants or heat rejection and supply, Our current approach is based on the upgrading of hio-oil produced by the hydrothermal liquefaction （HTL） of carbon-containing waste feedstocks, HTL can convert a variety of feedstocks into a bio-oil that requires much less upgrading than the products of other ways of deconstructing hiomass, We are now investigating the use of electrochemical processes for the further conversions needed to transform the hio-oil from HTL into fuel or higher value chemicals, We, and others, have shown that electrochemical reduction can offer adequate reaction rates and at least some of the nec- essary generality, In addition, an electrochemical reactor necessarily both oxidizes （removes electrons） on one side of the reactor and reduces （adds electrons） on the other side, Therefore, the two types of reac- tions could, in principle, he coupled to upgrade the hio-oil and simultaneously polish the water that is employed as a reactant and a carrier in the upstream HTL, Here, we overview a notional process, the possible conversion chemistry, and the economics of an HTL-electrochemical process,
基金Supported by The Profileringsfonds of the Maastricht University Medical Center(to Jacobs MJ and Buurman WA)an AGIKO-stipendium 920-03-522(to Lubbers T)from The Netherlands Organization for Health Research and Development
文摘AIM:To study the effect of circulating cell-free oxy-hemoglobin(FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS:To induce elevated intravascular circulating FHb,male Sprague-Dawley rats received water or FHb infusion.Microcirculatory changes in jejunum,ileum and colon were evaluated using fluorescent microspheres.Intestinal injury was quantified as plasmatic release of ileal lipid binding protein(iLBP) and verified by histological analysis of the ileum. RESULTS:Water and FHb infusions resulted,when compared with saline infusion,in reduced intestinal microcirculation(after 30 min P<0.05,or better;after 60 min FHb infusion P<0.05 for jejunum and colon) .Circulating FHb levels correlated significantly with release of iLBP(Spearman r=0.72,P=0.0011) .Epithelial cell injury of the villi was histologically observed after water and FHb infusions. CONCLUSION:This study shows that circulating FHb leads to a reduction in intestinal microcirculatory blood flow with marked injury to intestinal epithelial cells. These data support the hypothesis that circulating FHb contributes to the development of intestinal injury.
文摘Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper intends to fill this vacuum. It seeks to rediscover Epstein＇s communist experience, with particular focus on his fervent activism in and unapologetic defense of the Cultural Revolution. Through analyzing his experience, this paper exposes the essential allurement of Chinese communism encapsulated in the ideals of revolutionary regeneration and revolutionary virtues. Beyond Epstein＇s communist experience, this paper calls for a deeper and broader pondering on the analogy between communism and religion. Such an illuminating analogy should inspire more intellectual efforts than critical expositions of formalistic vainglory or personality cult.
文摘The 7th Biennial Conference of Chinese Ecological Economics Society (CEES) was held from 5th to 7th, Nov.2006 in Qingdao University. The paper summarizes the major viewpoint presented at the conference: eco-economicresearch and construction of a harmonious society in China. The conference put forward that it is an objectivity andinevitability for human being to enter the harmonious society, that eco-economics is one of the theoretical bases for theconstruction of the harmonious society, and that the research of eco-economics in China should reflect new contentsdeveloped in the process of modernization in China and make proper contributions to the construction of the harmonioussociety.
文摘We describe a patient with a Homo sapiens mutL homolog 1 (MLH1)-associated Lynch syndrome with previous diagnoses of two distinct primary cancers:a sigmoid colon cancer at the age of 39 years, and a right colon cancer at the age of 50 years. The mutation identified in his blood and buccal cells, c.1771delG, p.Asp591Ilefs*25, appears to be a de novo event, as it was not transmitted by either of his parents. This type of de novo event is rare in MLH1 as only three cases have been reported in the literature so far. Further-more, the discordant results observed between repli-cation error phenotyping and immunohistochemistry highlight the importance of the systematic use of both pre-screening tests in the molecular diagnosis of Lynch syndrome.
文摘The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a harmonious relationship between teachers and students, the positions of the teachers and students in teaching should be first made clear, and then an effective mental communication between teachers and students is necessarily available.
