The presidential research program Brain Research through Advancing Innovative Neurotechnologies(BRAIN)Initiative was established5years ago in the United States;it has been a driving force of the United States governme...The presidential research program Brain Research through Advancing Innovative Neurotechnologies(BRAIN)Initiative was established5years ago in the United States;it has been a driving force of the United States government and private factors to promote technology development in basic and translational neuroscience research.We here summarize the research plan and recent progress in cellular neuroscience,electrical and optical engineering,chemical and systems neurobiology,and brain mapping technologies.The research plan recognizes the importance of identifying different cell populations and unknown cell types in the human brain and diseased models.Technological advances in multielectrode arrays and chemical flow measurement probes not only demonstrate the capacity of detecting neural activities in large areas,but also enable a new era of studying the neural coding information.Large-scale coordination of neuronal activity and brain mapping information will allow for the identification of therapeutic targets in neurological disorders,which is benefited by big data acquisition and analysis.Specifically,increased brain databases will expedite the dissection of thoughts,emotions,cognition,and will thereby help the development of better understanding and treatments of brain disorders.Since cell therapy demonstrates potential for regenerative medicine,the utilization of the newly advanced technologies may further improve the translational potentials and precision controls of transplanted grafts.The development of new diagnostic and therapeutic tools also requires international collaborations on science,technology,advocating,healthcare and medical ethics to advance the innovation and clinical practices.展开更多
Since China put forward the Belt and Road Initiative and a community with shared future for mankind,mainstream media in the United States such as The Washington Post,The New York Times and The Wall Street Journal have...Since China put forward the Belt and Road Initiative and a community with shared future for mankind,mainstream media in the United States such as The Washington Post,The New York Times and The Wall Street Journal have given continuous reports.As the world’s superpower,the United States has a developed media system and a wide range of influence.The study extracted 173 valid texts from May 2015 to March 2020,among which only 5 reports were on a community with shared future for mankind.American media mainly reported from five aspects including economy,politics,cultural,security and environment,although there is no lack of certain sounds,there was more negative reports.It can provide a reference basis for our accurate response and creating a positive international public opinion environment that grasping the reporting trends on the Belt and Road Initiative and a community with shared future for mankind accurately.展开更多
Background： Criteria for determining brain death （BD） vary between China and the United States. We reported the results of an investigation designed to compare procedures to determine BD in two countries. Methods：...Background： Criteria for determining brain death （BD） vary between China and the United States. We reported the results of an investigation designed to compare procedures to determine BD in two countries. Methods： The latest criteria in the United states were published in 2010. The latest criteria in China were published in 2009. We used these two types of BD criteria to evaluate patients who were considered to be BD. The time, cost, and accuracy of the diagnosis were compared. Results： From January 1, 2012 to October 8, 2013, there were 37 patients which were applied for BD evaluation in the Neurological Intensive Care Unit of Beijing Tiantan Hospital. The cause of coma were known as subarachnoid hemorrhage （18 patients, 48.6%）, intracerebral hemorrhage （8 patients, 21.6%）, cerebral ischemia （9 patients, 24.3%）, brain stem tumor （1 patient, 2.7%）, and intracranial infection （1 patient, 2.7%）. The clinical examinations were done for all of the patients except 1 patient who had low blood pressure. Three patients had hrainstem reflexes that were excluded from BD. Twenty-five patients had apnea tests, and 20 tests were completed that were all positive. Confirmatory tests were completed differently： Transcranial Doppler （30 patients, positive rate 86.7%）, electroencephalogram （25 patients, positive rate 100%）, and somatosensory evoked potential （16 patients, positive rate 100%）. Thirty-three patients were diagnosed BD by criteria of the United States. Only 9 patients were diagnosed BD by Chinese criteria. The use of time and money in the USA criteria was obviously fewer than those in Chinese criteria （P = 0.000）. Conclusion： Compared with BD criteria of the United States, Chinese criteria were stricter, lower positive rate, more cost in money and time, and more reliable by families and doctors.展开更多
文摘The presidential research program Brain Research through Advancing Innovative Neurotechnologies(BRAIN)Initiative was established5years ago in the United States;it has been a driving force of the United States government and private factors to promote technology development in basic and translational neuroscience research.We here summarize the research plan and recent progress in cellular neuroscience,electrical and optical engineering,chemical and systems neurobiology,and brain mapping technologies.The research plan recognizes the importance of identifying different cell populations and unknown cell types in the human brain and diseased models.Technological advances in multielectrode arrays and chemical flow measurement probes not only demonstrate the capacity of detecting neural activities in large areas,but also enable a new era of studying the neural coding information.Large-scale coordination of neuronal activity and brain mapping information will allow for the identification of therapeutic targets in neurological disorders,which is benefited by big data acquisition and analysis.Specifically,increased brain databases will expedite the dissection of thoughts,emotions,cognition,and will thereby help the development of better understanding and treatments of brain disorders.Since cell therapy demonstrates potential for regenerative medicine,the utilization of the newly advanced technologies may further improve the translational potentials and precision controls of transplanted grafts.The development of new diagnostic and therapeutic tools also requires international collaborations on science,technology,advocating,healthcare and medical ethics to advance the innovation and clinical practices.
基金Postgraduate Innovation Program of Jiangsu Province in 2020:research on the construction of a community of shared future for mankind from the perspective of Marx’s thoery of world history(KYCX20_3060)Key projects in 2017 of The National Social Science Fund of China“The spread of Chinese traditional elementary school among countries in‘the Belt and Road Initiative’”(No.17AZS012)Teaching reform and research topics of Jiangsu University“Research on the construction of the mixed teaching mode of‘Internet+ideological and political courses’”(No.2019JGZD014)。
文摘Since China put forward the Belt and Road Initiative and a community with shared future for mankind,mainstream media in the United States such as The Washington Post,The New York Times and The Wall Street Journal have given continuous reports.As the world’s superpower,the United States has a developed media system and a wide range of influence.The study extracted 173 valid texts from May 2015 to March 2020,among which only 5 reports were on a community with shared future for mankind.American media mainly reported from five aspects including economy,politics,cultural,security and environment,although there is no lack of certain sounds,there was more negative reports.It can provide a reference basis for our accurate response and creating a positive international public opinion environment that grasping the reporting trends on the Belt and Road Initiative and a community with shared future for mankind accurately.
文摘Background： Criteria for determining brain death （BD） vary between China and the United States. We reported the results of an investigation designed to compare procedures to determine BD in two countries. Methods： The latest criteria in the United states were published in 2010. The latest criteria in China were published in 2009. We used these two types of BD criteria to evaluate patients who were considered to be BD. The time, cost, and accuracy of the diagnosis were compared. Results： From January 1, 2012 to October 8, 2013, there were 37 patients which were applied for BD evaluation in the Neurological Intensive Care Unit of Beijing Tiantan Hospital. The cause of coma were known as subarachnoid hemorrhage （18 patients, 48.6%）, intracerebral hemorrhage （8 patients, 21.6%）, cerebral ischemia （9 patients, 24.3%）, brain stem tumor （1 patient, 2.7%）, and intracranial infection （1 patient, 2.7%）. The clinical examinations were done for all of the patients except 1 patient who had low blood pressure. Three patients had hrainstem reflexes that were excluded from BD. Twenty-five patients had apnea tests, and 20 tests were completed that were all positive. Confirmatory tests were completed differently： Transcranial Doppler （30 patients, positive rate 86.7%）, electroencephalogram （25 patients, positive rate 100%）, and somatosensory evoked potential （16 patients, positive rate 100%）. Thirty-three patients were diagnosed BD by criteria of the United States. Only 9 patients were diagnosed BD by Chinese criteria. The use of time and money in the USA criteria was obviously fewer than those in Chinese criteria （P = 0.000）. Conclusion： Compared with BD criteria of the United States, Chinese criteria were stricter, lower positive rate, more cost in money and time, and more reliable by families and doctors.
