To enhance the separation selectivity of Mg-MOF-74 towards CO_(2) in a CO_(2)/N_(2) mixture,a series of Mg-MOF-74 and Ni_(x)/Mg_(1-x)-MOF-74 adsorbents were prepared by solvothermal synthesis in this paper.It was foun...To enhance the separation selectivity of Mg-MOF-74 towards CO_(2) in a CO_(2)/N_(2) mixture,a series of Mg-MOF-74 and Ni_(x)/Mg_(1-x)-MOF-74 adsorbents were prepared by solvothermal synthesis in this paper.It was found that the adsorption capacity of Mg-MOF-74 for CO_(2) could be effectively increased by optimizing the amount of acetic acid.On this basis,the bimetal MOF-74 adsorbent was prepared by metal modification.The multi-component dynamic adsorption penetration analysis was utilized to examine the CO_(2) adsorption capacity and CO_(2)/N_(2) selectivity of the diverse adsorbent materials.The results showed that Ni0.11/Mg0.89-MOF-74 showed a CO_(2) adsorption capacity of 7.02 mmol/g under pure CO_(2) atmosphere and had a selectivity of 20.50 for CO_(2)/N_(2) under 15% CO_(2)/85%N_(2) conditions,which was 10.2% and 18.02% higher than that of Mg-MOF-74 respectively.Combining XPS,SEM and N_(2) adsorption-desorption characterization analysis,it was attributed to the effect of the more stable unsaturated metal sites Ni into the Mg-MOF-74 on the pore structure and the synergistic interaction between the two metals.Density Functional Theory(DFT)simulations revealed that the synergistic interaction between modulated the electrostatic potential strength and gradient of the material,which was more favorable for the adsorption of CO_(2) molecules with small diameters and large quadrupole moment.In addition,the Ni0.11/Mg0.89-MOF-74 showed commendable cyclic stability,underscoring its promising potential for practical applications.展开更多
Size distribution of nano-carbides produced by duplex treatments of surface nanocrystallization(by surface severe plastic deformation) and plasma electrolytic carburizing on CP-Ti was investigated.Skewness and kurtosi...Size distribution of nano-carbides produced by duplex treatments of surface nanocrystallization(by surface severe plastic deformation) and plasma electrolytic carburizing on CP-Ti was investigated.Skewness and kurtosis of Gussian shape distribution curves were studied and the effect of time was determined.The usage of longer time is more suitable for achieving less size of complex nano-carbides.Surface roughness of treated samples was measured.It is observed that there is an optimum level for time on surface roughness increasing(difference between two measured data).展开更多
True Boiling Point (TBP) distillation is one of the most common experimental techniques for determination of petroleum properties. The methods for performing TBP distillation experiments are described by ASTM D2892 ...True Boiling Point (TBP) distillation is one of the most common experimental techniques for determination of petroleum properties. The methods for performing TBP distillation experiments are described by ASTM D2892 and by ASTM D5236. However, these methods are established for petroleum fractions that reach temperatures up to 565 ~C. In this work, two petroleum residues were distilled in a falling film molecular distillation prototype and the data were used to obtain the extension of the TBP curve above a temperature of 565 ~C. It was possible to extend the TBP curve of both petroleum up to temperatures close to 700 ~C with consistency and continuity in comparison to the standard curve. In addition, an amount of raw material that was been treated as residue could be reused.展开更多
Effects of heat and mass transfer in the flow of Burgers fluid over an inclined sheet are discussed. Problems formulation and relevant analysis are given in the presence of thermal radiation and non-uniform heat sourc...Effects of heat and mass transfer in the flow of Burgers fluid over an inclined sheet are discussed. Problems formulation and relevant analysis are given in the presence of thermal radiation and non-uniform heat source/sink. Thermal conductivity is taken temperature dependent. The nonlinear partial differential equations are simplified using boundary layer approximations. The resultant nonlinear ordinary differential equations are solved for the series solutions. The convergence of series solutions is obtained by plotting theη-curves for the velocity, temperature and concentration fields. Results of this work describe the role of different physical parameters involved in the problem. The Deborah numbers corresponding to relaxation time(β1 and β2) and angle of inclination(α) decrease the fluid velocity and concentration field. Concentration field decays as Deborah numbers corresponding to retardation time(β3) and mixed convection parameter(G) increase. Large values of heat generation/absorption parameters A/B, and the temperature distribution across the boundary layer increase. Numerical values of local Nusselt number,-θ′(0), and local Sherwood number,-f′(0), are computed and analyzed. It is found that θ′(0) increases with an increase in β3.展开更多
The isothermal extrusion process of hollow aluminium profile was investigated using incremental proportional-integral-derivative(PID)control algorithm and finite element simulations.The range of extrusion speed was de...The isothermal extrusion process of hollow aluminium profile was investigated using incremental proportional-integral-derivative(PID)control algorithm and finite element simulations.The range of extrusion speed was determined by considering the maximum extrusion load and production efficiency.By taking the optimal solution temperature of the secondary phase as the target temperature,the extrusion speed–stroke curve for realizing the isothermal extrusion of the aluminium profile was obtained.Results show that in the traditional constant extrusion speed process,the average temperature of the cross-section of the aluminium profile at the die exit rapidly increases and then slowly rises with the increase in ram displacement.As the extrusion speed increases,the temperature difference at the die exit of the profile along the extrusion direction increases.The exit temperature difference between the front and back ends of the extrudate along the extrusion direction obtained by adopting isothermal extrusion is about 6.9℃.Furthermore,the heat generated by plastic deformation and friction during extrusion is balanced with the heat transfer from the workpiece to the container,porthole die and external environment.展开更多
Objective: To determine the clinical serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9), individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases ...Objective: To determine the clinical serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9), individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods: The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating characteristic (ROC) curves were plotted. Results: Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined: in esophageal cancer, sensitivity=28%, negative predictive value (NPV)=61.72%, and AUC=0.742 (SE=0.05), with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 (SE=0.0S), with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 (SE=0.04), with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated: in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 (SE=0.05), with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 (SE=0.05), with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 (SE=0.05), with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined: in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 (95% CI: 0.0159-0.322); gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 (9$% CI: -0.0866-0.198); and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 (9S% CI: 0.137-0.415). Conclusion: CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.展开更多
The flow field of pulsing air separation is normally in an unsteady turbulence state.With the application of the basic principles of multiphase turbulent flows,we established the dynamical computational model,which sh...The flow field of pulsing air separation is normally in an unsteady turbulence state.With the application of the basic principles of multiphase turbulent flows,we established the dynamical computational model,which shows a remarkable variation of the unstable pulsing air flow field.CFD(computational fluid dynamics) was used to conduct the numerical simulation of the actual geometric model of the classifier.The inside velocity of the flowing fields was analyzed later.The simulation results indicate that the designed structure of the active pulsing air classifier provided a favorable environment for the separation of the particles with different physical characters by density.We shot the movement behaviors of the typical tracer grains in the active pulsing flow field using a high speed dynamic camera.The displacement and velocity curves of the particles in the continuous impulse periods were then analyzed.The experimental results indicate that the effective separation by density of the particles with the same settling velocity and different ranges of the density and particle size can be achieved in the active pulsing airflow field.The experimental results provide an agreement with the simulation results.展开更多
Drill machines used in surface mines, particularly in coal, is characterized by a very poor utilization (around 40%) and low availability (around 60%). The main purpose of this study is to develop a drill selec- t...Drill machines used in surface mines, particularly in coal, is characterized by a very poor utilization (around 40%) and low availability (around 60%). The main purpose of this study is to develop a drill selec- tion methodology and simultaneously a performance evaluation technique based on drill cuttings produced and drilling rate achieved. In all 28 blast drilled through were investigated. The drilling was accomplished by 5 different drill machines of Ingersoll-Rand and Revathi working in coal mines of Sonepur Bazari (SECL) and Block-II (BCCL). The drills are Rotary and Rotary Percussive type using tri- cone rock roller bits. Drill cuttings were collected and sieve analysis was done in the laboratory. Using Rosin Ramler Diagram, coarseness index (CI), mean chip size (d), specific-st trace area (SSA) and charac- teristic particle size distribution curves for all the holes drilled were plotted. The predictor equation for drill penetration rate established through multiple regressions was found to have a very good correlation with an index of determination of 0.85. A comparative analysis of particle size distribution curves was used to evaluate the drill efficiency. The suggested approach utilises the area under the curve, after the point of trend reversal and brittleness ratio of the respective bench to arrive at drill energy utilization index (DEUI), for mapping of drill machine to bench, The developed DEU1 can aid in selecting or mapping a right machine to right bench for achieving higher penetration rate and utilizations.展开更多
CDW (construction and demolition wastes) present a high amount of aggregate chips covered with mortar. This results in high absorption of water with a direct impact in particle breakage or disaggregation. It is supp...CDW (construction and demolition wastes) present a high amount of aggregate chips covered with mortar. This results in high absorption of water with a direct impact in particle breakage or disaggregation. It is supposed that intra particle suction plays an important role in this phenomenon. However, WRCs (water retention curves) of CDW are not well understood. In this work, the WRCs of dynamically compacted specimens of aggregates recycled from the demolition of the National Stadium in Brasilia are studied. The objective of this study is to obtain WRCs of the recycled materials by using the pressure plate and filter paper methods. The breaking effect during compaction is quantified from the grain size distribution curves. The particle breakage during compaction increases when the energy is augmented. The results from the WRCs were incorporated into a pore size capillary model to predict pore size distribution.展开更多
Reduction of drag torque in disengaged wet clutch is one of important potentials for vehicle transmission improvement. The flow of the oil film in clutch clearance is investigated. A three-dimension Navier-Stokes(N-S)...Reduction of drag torque in disengaged wet clutch is one of important potentials for vehicle transmission improvement. The flow of the oil film in clutch clearance is investigated. A three-dimension Navier-Stokes(N-S) equation based on laminar flow is presented to model the drag torque. Pressure and speed distribution in radial and circumferential directions are deduced. The theoretical analysis reveals that oil flow acceleration in radial direction caused by centrifugal force is the key reason for the shrinking of oil film as constant feeding flow rate. The peak drag torque occurs at the beginning of oil film shrinking. A variable is introduced to describe effective oil film area and drag torque after oil film shrinking is well evaluated with the variable. Under the working condition, tests were made to obtain drag torque curves at different clutch speed and oil viscosity. The tests confirm that simulation results agree with test data. The model performs well in the prediction of drag torque and lays a theoretical foundation to reduce it.展开更多
The maximum entropy distribution, which consists of various recognized theoretical distributions, is a better curve to estimate the design thickness of sea ice. Method of moment and empirical curve fitting method are ...The maximum entropy distribution, which consists of various recognized theoretical distributions, is a better curve to estimate the design thickness of sea ice. Method of moment and empirical curve fitting method are common-used parameter estimation methods for maximum entropy distribution. In this study, we propose to use the particle swarm optimization method as a new parameter estimation method for the maximum entropy distribution, which has the advantage to avoid deviation introduced by simplifications made in other methods. We conducted a case study to fit the hindcasted thickness of the sea ice in the Liaodong Bay of Bohai Sea using these three parameter-estimation methods for the maximum entropy distribution. All methods implemented in this study pass the K-S tests at 0.05 significant level. In terms of the average sum of deviation squares, the empirical curve fitting method provides the best fit for the original data, while the method of moment provides the worst. Among all three methods, the particle swarm optimization method predicts the largest thickness of the sea ice for a same return period. As a result, we recommend using the particle swarm optimization method for the maximum entropy distribution for offshore structures mainly influenced by the sea ice in winter, but using the empirical curve fitting method to reduce the cost in the design of temporary and economic buildings.展开更多
The size of bubbles created in the flotation process is of great importance to the efficiency of the mineral separation achieved.Meanwhile,it is believed that frother transport between phases is perhaps the most impor...The size of bubbles created in the flotation process is of great importance to the efficiency of the mineral separation achieved.Meanwhile,it is believed that frother transport between phases is perhaps the most important reason for the interactive nature of the phenomena occurring in the bulk and froth phases in flotation,as frother adsorbed in the surface of rising bubbles is removed from the bulk phase and then released into the froth as a fraction of the bubbles burst.This causes the increased concentration in the froth compared to the bulk concentration,named as frother partitioning.Partitioning reflects the adsorption of frother on bubbles and how to influence bubble size is not known.There currently exists no such a topic aiming to link these two key parameters.To fill this vacancy,the correspondence between bubble size and frother partitioning was examined.Bubble size was measured by sampling-for-imaging(SFI)technique.Using total organic carbon(TOC)analysis to measure the frother partitioning between froth and bulk phases was determined.Measurements have shown,with no exceptions including four different frothers,higher frother concentration is in the bulk than in the froth.The results also show strong partitioning giving an increase in bubble size which implies there is a compelling relationship between these two,represented by CFroth/CBulk and D32.The CFroth/CBulkand D32 curves show similar exponential decay relationships as a function of added frother in the system,strongly suggesting that the frother concentration gradient between the bulk solution and the bubble interface is the driving force contributing to bubble size reduction.展开更多
A new model is established to describe heat exchanging of the incompletely mixed fluid flowing in the tubes and the unmixed fluid crossing out of the tubes in the heat-exchangers especially in air cooler. In the model...A new model is established to describe heat exchanging of the incompletely mixed fluid flowing in the tubes and the unmixed fluid crossing out of the tubes in the heat-exchangers especially in air cooler. In the model, a new method of analyzing volume is proposed to develop the temperature distribution equations of the two fluids --tw(x) and ta(X,,7"). With tw(x) and ta (x, ,7), the curves of the temperature distribution of the two fluids can be obtained. Also tw(x) and ta(x,n) can be used to calculate parameters of structure of an air cooler and to improve performances of it.展开更多
The aim of the experiment is to analyze and view the distribution of gangue withdifferent particle sizes in mine spoil pile cross section.According to the Dimensionalmethod,'Pi'theorem was employed first to ab...The aim of the experiment is to analyze and view the distribution of gangue withdifferent particle sizes in mine spoil pile cross section.According to the Dimensionalmethod,'Pi'theorem was employed first to abbreviate ten physical and mechanical parametersto three dimensionless groups, and then the similarity criterion and coefficient ofthe experiment were determined and calculated based on particle size distribution curve.The similarity model was designed and constructed to represent the process of the minespoil pile.The profile of the final model shows that the small sized particles mainly composethe upper zone of the mine spoil pile, while the bottom of the pile is dominated bybigger sized particles, and the intermediate section presents a zigzag stripe cross-beddingstructure which is composed by small-medium scale particles and medium-large scaleparticles.Each stripe has two critical angles: one is the angle in which gangue particlescan maintain their stability condition, with approximate range from 24° to 26°; and theother is the angle in which particles can stop gliding downwards, approximately varyingfrom 34° to 36°.展开更多
The characteristics of density yield curve of coal and distribution curve of products can be described with median, quartile deviation, the quartile measure of skewness and kurtosis like K. On the basis of 16 groups o...The characteristics of density yield curve of coal and distribution curve of products can be described with median, quartile deviation, the quartile measure of skewness and kurtosis like K. On the basis of 16 groups of coal density composition data and their jigging stratification data derived from the pilot jig, the regression analysis has been done for the relationship between the characteristic values of the density curve and the characteristic values of the distribution curve.The results show as follow: (1) The bigger the skewness of the density curve, the bigger the probable error (Ep) and imperfection (I ) are. (2) The bigger the median of density curve, the smaller the probable error or imperfection is. (3) The characteristic values of density curve have no influence on the kurtosis K of the distribution curve.展开更多
The van Genuchten model is the most widely used soil water retention curve (SWRC) model. Two undisturbed soils (clay and loam) were used to evaluate the accuracy of the integral method to estimate van Genuchten mo...The van Genuchten model is the most widely used soil water retention curve (SWRC) model. Two undisturbed soils (clay and loam) were used to evaluate the accuracy of the integral method to estimate van Genuchten model parameters and to determine SWRCs of undisturbed soils. SWRCs calculated by the integral method were compared with those measured by a high speed centrifuge technique. The accuracy of the calculated results was evaluated graphically, as well as by root mean square error (RMSE), normalized root mean square error (NRMSE) and Willmott's index of agreement (1). The results obtained from the integral method were quite similar to those by the centrifuge technique. The RMSEs (4.61 ×10^-5 for Eum-Orthic Anthrosol and 2.74 × 10^-4 for Los-Orthic Entisol) and NRMSEs (1.56 × 10^-4 for Eum- Orthic Anthrosol and 1.45 ×10^-3 for Los-Orthic Entisol) were relatively small. The 1 values were 0.973 and 0.943 for Eum-Orthic Anthrosol and Los-Orthic Entisol, respectively, indicating a good agreement between the integral method values and the centrifuge values. Therefore, the integral method could be used to estimate SWRCs of undisturbed clay and loam soils.展开更多
An asymptotic semi-analytical method for heat transfer in counter-flow honeycomb regenerator is proposed. By introducing a combined heat-transfer coefficient between the gas and solid phase, a heat transfer model is b...An asymptotic semi-analytical method for heat transfer in counter-flow honeycomb regenerator is proposed. By introducing a combined heat-transfer coefficient between the gas and solid phase, a heat transfer model is built based on the thin-walled assumption. The dimensionless thermal equation is deduced by considering solid heat conduction along the passage length. The asymptotic analysis is used for the small parameter of heat conduction term in equation. The first order asymptotic solution to temperature distribution under weak solid heat conduction is achieved after Laplace transformation through the multiple scales method and the symbolic manipulation function in MATLAB. Semi-analytical solutions agree with tests and finite-difference numerical results. It is proved possible for the asymptotic analysis to improve the effectiveness, economics and precision of thermal research on regenerator.展开更多
基金supported by National Natural Science Foundation of China(U23A20100)the Strategic Priority Research Program(A)of the Chinese Academy of Sciences(XDA0390404)+5 种基金ICC CAS SCJC-DT-2023-03,the Foundation of State Key Laboratory of Coal Conversion(J24-25-619)Youth Innovation Promotion Association CAS(2018209,2020179)Key R&D Program of Shanxi Province(202102090301008,202202090301013)the special fund for S&T Innovation Team of Shanxi Province(202204051001012)Project of International Cooperation and Exchange NSFC-RFBR(22011530069)Tianjin Science and Technology Plan Project(22YFYSHZ00290)。
文摘To enhance the separation selectivity of Mg-MOF-74 towards CO_(2) in a CO_(2)/N_(2) mixture,a series of Mg-MOF-74 and Ni_(x)/Mg_(1-x)-MOF-74 adsorbents were prepared by solvothermal synthesis in this paper.It was found that the adsorption capacity of Mg-MOF-74 for CO_(2) could be effectively increased by optimizing the amount of acetic acid.On this basis,the bimetal MOF-74 adsorbent was prepared by metal modification.The multi-component dynamic adsorption penetration analysis was utilized to examine the CO_(2) adsorption capacity and CO_(2)/N_(2) selectivity of the diverse adsorbent materials.The results showed that Ni0.11/Mg0.89-MOF-74 showed a CO_(2) adsorption capacity of 7.02 mmol/g under pure CO_(2) atmosphere and had a selectivity of 20.50 for CO_(2)/N_(2) under 15% CO_(2)/85%N_(2) conditions,which was 10.2% and 18.02% higher than that of Mg-MOF-74 respectively.Combining XPS,SEM and N_(2) adsorption-desorption characterization analysis,it was attributed to the effect of the more stable unsaturated metal sites Ni into the Mg-MOF-74 on the pore structure and the synergistic interaction between the two metals.Density Functional Theory(DFT)simulations revealed that the synergistic interaction between modulated the electrostatic potential strength and gradient of the material,which was more favorable for the adsorption of CO_(2) molecules with small diameters and large quadrupole moment.In addition,the Ni0.11/Mg0.89-MOF-74 showed commendable cyclic stability,underscoring its promising potential for practical applications.
基金Partial work of this project funded by National Elite Foundation of Iran and Iranian Nanotechnology Initiative is appreciated.
文摘Size distribution of nano-carbides produced by duplex treatments of surface nanocrystallization(by surface severe plastic deformation) and plasma electrolytic carburizing on CP-Ti was investigated.Skewness and kurtosis of Gussian shape distribution curves were studied and the effect of time was determined.The usage of longer time is more suitable for achieving less size of complex nano-carbides.Surface roughness of treated samples was measured.It is observed that there is an optimum level for time on surface roughness increasing(difference between two measured data).
文摘True Boiling Point (TBP) distillation is one of the most common experimental techniques for determination of petroleum properties. The methods for performing TBP distillation experiments are described by ASTM D2892 and by ASTM D5236. However, these methods are established for petroleum fractions that reach temperatures up to 565 ~C. In this work, two petroleum residues were distilled in a falling film molecular distillation prototype and the data were used to obtain the extension of the TBP curve above a temperature of 565 ~C. It was possible to extend the TBP curve of both petroleum up to temperatures close to 700 ~C with consistency and continuity in comparison to the standard curve. In addition, an amount of raw material that was been treated as residue could be reused.
文摘Effects of heat and mass transfer in the flow of Burgers fluid over an inclined sheet are discussed. Problems formulation and relevant analysis are given in the presence of thermal radiation and non-uniform heat source/sink. Thermal conductivity is taken temperature dependent. The nonlinear partial differential equations are simplified using boundary layer approximations. The resultant nonlinear ordinary differential equations are solved for the series solutions. The convergence of series solutions is obtained by plotting theη-curves for the velocity, temperature and concentration fields. Results of this work describe the role of different physical parameters involved in the problem. The Deborah numbers corresponding to relaxation time(β1 and β2) and angle of inclination(α) decrease the fluid velocity and concentration field. Concentration field decays as Deborah numbers corresponding to retardation time(β3) and mixed convection parameter(G) increase. Large values of heat generation/absorption parameters A/B, and the temperature distribution across the boundary layer increase. Numerical values of local Nusselt number,-θ′(0), and local Sherwood number,-f′(0), are computed and analyzed. It is found that θ′(0) increases with an increase in β3.
基金the financial supports from the National Natural Science Foundation of China(No.52005244)the Scientific Research Fund of Hunan Provincial Education Department,China(Nos.18B285,18B552)+1 种基金the Natural Science Foundation of Hunan Provincial,China(Nos.2019JJ50510,2019JJ70077)Young Scholars Program of Furong Scholar Program,China.
文摘The isothermal extrusion process of hollow aluminium profile was investigated using incremental proportional-integral-derivative(PID)control algorithm and finite element simulations.The range of extrusion speed was determined by considering the maximum extrusion load and production efficiency.By taking the optimal solution temperature of the secondary phase as the target temperature,the extrusion speed–stroke curve for realizing the isothermal extrusion of the aluminium profile was obtained.Results show that in the traditional constant extrusion speed process,the average temperature of the cross-section of the aluminium profile at the die exit rapidly increases and then slowly rises with the increase in ram displacement.As the extrusion speed increases,the temperature difference at the die exit of the profile along the extrusion direction increases.The exit temperature difference between the front and back ends of the extrudate along the extrusion direction obtained by adopting isothermal extrusion is about 6.9℃.Furthermore,the heat generated by plastic deformation and friction during extrusion is balanced with the heat transfer from the workpiece to the container,porthole die and external environment.
基金the financial support provided by the Biotechnology Information Service–Sub-Distributed Information Centre(supported by the Department of Biotechnology,Government of India)Advanced Bioinformatics Centre(supported by the Government of Rajasthan)at Birla Institute of Scientific Research for the infrastructure and facilities for conducting statistical work
文摘Objective: To determine the clinical serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9), individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods: The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating characteristic (ROC) curves were plotted. Results: Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined: in esophageal cancer, sensitivity=28%, negative predictive value (NPV)=61.72%, and AUC=0.742 (SE=0.05), with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 (SE=0.0S), with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 (SE=0.04), with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated: in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 (SE=0.05), with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 (SE=0.05), with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 (SE=0.05), with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined: in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 (95% CI: 0.0159-0.322); gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 (9$% CI: -0.0866-0.198); and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 (9S% CI: 0.137-0.415). Conclusion: CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.
基金the financial support provided by the National Natural Science Foundation of China (No.51074156)the Natural Science Foundation of China for InnovativeResearch Group (No. 50921002)+1 种基金the Natural Science Foundation of Jiangsu Province of China (No. BK2010002)the Fundamental Research Funds for the Central Universities (No. 2010ZDP01A06)
文摘The flow field of pulsing air separation is normally in an unsteady turbulence state.With the application of the basic principles of multiphase turbulent flows,we established the dynamical computational model,which shows a remarkable variation of the unstable pulsing air flow field.CFD(computational fluid dynamics) was used to conduct the numerical simulation of the actual geometric model of the classifier.The inside velocity of the flowing fields was analyzed later.The simulation results indicate that the designed structure of the active pulsing air classifier provided a favorable environment for the separation of the particles with different physical characters by density.We shot the movement behaviors of the typical tracer grains in the active pulsing flow field using a high speed dynamic camera.The displacement and velocity curves of the particles in the continuous impulse periods were then analyzed.The experimental results indicate that the effective separation by density of the particles with the same settling velocity and different ranges of the density and particle size can be achieved in the active pulsing airflow field.The experimental results provide an agreement with the simulation results.
文摘Drill machines used in surface mines, particularly in coal, is characterized by a very poor utilization (around 40%) and low availability (around 60%). The main purpose of this study is to develop a drill selec- tion methodology and simultaneously a performance evaluation technique based on drill cuttings produced and drilling rate achieved. In all 28 blast drilled through were investigated. The drilling was accomplished by 5 different drill machines of Ingersoll-Rand and Revathi working in coal mines of Sonepur Bazari (SECL) and Block-II (BCCL). The drills are Rotary and Rotary Percussive type using tri- cone rock roller bits. Drill cuttings were collected and sieve analysis was done in the laboratory. Using Rosin Ramler Diagram, coarseness index (CI), mean chip size (d), specific-st trace area (SSA) and charac- teristic particle size distribution curves for all the holes drilled were plotted. The predictor equation for drill penetration rate established through multiple regressions was found to have a very good correlation with an index of determination of 0.85. A comparative analysis of particle size distribution curves was used to evaluate the drill efficiency. The suggested approach utilises the area under the curve, after the point of trend reversal and brittleness ratio of the respective bench to arrive at drill energy utilization index (DEUI), for mapping of drill machine to bench, The developed DEU1 can aid in selecting or mapping a right machine to right bench for achieving higher penetration rate and utilizations.
文摘CDW (construction and demolition wastes) present a high amount of aggregate chips covered with mortar. This results in high absorption of water with a direct impact in particle breakage or disaggregation. It is supposed that intra particle suction plays an important role in this phenomenon. However, WRCs (water retention curves) of CDW are not well understood. In this work, the WRCs of dynamically compacted specimens of aggregates recycled from the demolition of the National Stadium in Brasilia are studied. The objective of this study is to obtain WRCs of the recycled materials by using the pressure plate and filter paper methods. The breaking effect during compaction is quantified from the grain size distribution curves. The particle breakage during compaction increases when the energy is augmented. The results from the WRCs were incorporated into a pore size capillary model to predict pore size distribution.
基金supported by National Defense Arming Pre-researching Project(Grant No. 40402060102)
文摘Reduction of drag torque in disengaged wet clutch is one of important potentials for vehicle transmission improvement. The flow of the oil film in clutch clearance is investigated. A three-dimension Navier-Stokes(N-S) equation based on laminar flow is presented to model the drag torque. Pressure and speed distribution in radial and circumferential directions are deduced. The theoretical analysis reveals that oil flow acceleration in radial direction caused by centrifugal force is the key reason for the shrinking of oil film as constant feeding flow rate. The peak drag torque occurs at the beginning of oil film shrinking. A variable is introduced to describe effective oil film area and drag torque after oil film shrinking is well evaluated with the variable. Under the working condition, tests were made to obtain drag torque curves at different clutch speed and oil viscosity. The tests confirm that simulation results agree with test data. The model performs well in the prediction of drag torque and lays a theoretical foundation to reduce it.
基金supported by the National Natural Science Foundation of China (Nos. 51279186, 51479183, 51509227)the Shandong Province Natural Science Foundation, China (No. ZR2014EEQ030)the Fundamental Research Funds for the Central Universities (No. 201413003)
文摘The maximum entropy distribution, which consists of various recognized theoretical distributions, is a better curve to estimate the design thickness of sea ice. Method of moment and empirical curve fitting method are common-used parameter estimation methods for maximum entropy distribution. In this study, we propose to use the particle swarm optimization method as a new parameter estimation method for the maximum entropy distribution, which has the advantage to avoid deviation introduced by simplifications made in other methods. We conducted a case study to fit the hindcasted thickness of the sea ice in the Liaodong Bay of Bohai Sea using these three parameter-estimation methods for the maximum entropy distribution. All methods implemented in this study pass the K-S tests at 0.05 significant level. In terms of the average sum of deviation squares, the empirical curve fitting method provides the best fit for the original data, while the method of moment provides the worst. Among all three methods, the particle swarm optimization method predicts the largest thickness of the sea ice for a same return period. As a result, we recommend using the particle swarm optimization method for the maximum entropy distribution for offshore structures mainly influenced by the sea ice in winter, but using the empirical curve fitting method to reduce the cost in the design of temporary and economic buildings.
基金Project supported by the Collaborative Research and Development Program of Natural Sciences and Engineering Research Council of Canada
文摘The size of bubbles created in the flotation process is of great importance to the efficiency of the mineral separation achieved.Meanwhile,it is believed that frother transport between phases is perhaps the most important reason for the interactive nature of the phenomena occurring in the bulk and froth phases in flotation,as frother adsorbed in the surface of rising bubbles is removed from the bulk phase and then released into the froth as a fraction of the bubbles burst.This causes the increased concentration in the froth compared to the bulk concentration,named as frother partitioning.Partitioning reflects the adsorption of frother on bubbles and how to influence bubble size is not known.There currently exists no such a topic aiming to link these two key parameters.To fill this vacancy,the correspondence between bubble size and frother partitioning was examined.Bubble size was measured by sampling-for-imaging(SFI)technique.Using total organic carbon(TOC)analysis to measure the frother partitioning between froth and bulk phases was determined.Measurements have shown,with no exceptions including four different frothers,higher frother concentration is in the bulk than in the froth.The results also show strong partitioning giving an increase in bubble size which implies there is a compelling relationship between these two,represented by CFroth/CBulk and D32.The CFroth/CBulkand D32 curves show similar exponential decay relationships as a function of added frother in the system,strongly suggesting that the frother concentration gradient between the bulk solution and the bubble interface is the driving force contributing to bubble size reduction.
文摘A new model is established to describe heat exchanging of the incompletely mixed fluid flowing in the tubes and the unmixed fluid crossing out of the tubes in the heat-exchangers especially in air cooler. In the model, a new method of analyzing volume is proposed to develop the temperature distribution equations of the two fluids --tw(x) and ta(X,,7"). With tw(x) and ta (x, ,7), the curves of the temperature distribution of the two fluids can be obtained. Also tw(x) and ta(x,n) can be used to calculate parameters of structure of an air cooler and to improve performances of it.
基金Supported by the National Natural Science Foundation of China(50874102,50974070)
文摘The aim of the experiment is to analyze and view the distribution of gangue withdifferent particle sizes in mine spoil pile cross section.According to the Dimensionalmethod,'Pi'theorem was employed first to abbreviate ten physical and mechanical parametersto three dimensionless groups, and then the similarity criterion and coefficient ofthe experiment were determined and calculated based on particle size distribution curve.The similarity model was designed and constructed to represent the process of the minespoil pile.The profile of the final model shows that the small sized particles mainly composethe upper zone of the mine spoil pile, while the bottom of the pile is dominated bybigger sized particles, and the intermediate section presents a zigzag stripe cross-beddingstructure which is composed by small-medium scale particles and medium-large scaleparticles.Each stripe has two critical angles: one is the angle in which gangue particlescan maintain their stability condition, with approximate range from 24° to 26°; and theother is the angle in which particles can stop gliding downwards, approximately varyingfrom 34° to 36°.
文摘The characteristics of density yield curve of coal and distribution curve of products can be described with median, quartile deviation, the quartile measure of skewness and kurtosis like K. On the basis of 16 groups of coal density composition data and their jigging stratification data derived from the pilot jig, the regression analysis has been done for the relationship between the characteristic values of the density curve and the characteristic values of the distribution curve.The results show as follow: (1) The bigger the skewness of the density curve, the bigger the probable error (Ep) and imperfection (I ) are. (2) The bigger the median of density curve, the smaller the probable error or imperfection is. (3) The characteristic values of density curve have no influence on the kurtosis K of the distribution curve.
基金Project supported by the International Partnership Program for Creative Research Teams of the Chinese Academy of Sciences (CAS) & the State Administration of Foreign Experts Affairs (SAFEA), China, and the Hundreds-Talent Program of the Chinese Academy of Sciences, China (No. 90502006)
文摘The van Genuchten model is the most widely used soil water retention curve (SWRC) model. Two undisturbed soils (clay and loam) were used to evaluate the accuracy of the integral method to estimate van Genuchten model parameters and to determine SWRCs of undisturbed soils. SWRCs calculated by the integral method were compared with those measured by a high speed centrifuge technique. The accuracy of the calculated results was evaluated graphically, as well as by root mean square error (RMSE), normalized root mean square error (NRMSE) and Willmott's index of agreement (1). The results obtained from the integral method were quite similar to those by the centrifuge technique. The RMSEs (4.61 ×10^-5 for Eum-Orthic Anthrosol and 2.74 × 10^-4 for Los-Orthic Entisol) and NRMSEs (1.56 × 10^-4 for Eum- Orthic Anthrosol and 1.45 ×10^-3 for Los-Orthic Entisol) were relatively small. The 1 values were 0.973 and 0.943 for Eum-Orthic Anthrosol and Los-Orthic Entisol, respectively, indicating a good agreement between the integral method values and the centrifuge values. Therefore, the integral method could be used to estimate SWRCs of undisturbed clay and loam soils.
基金Supported by Chinese National Programs for High Technology Research and Development (No. 2001AA514013)
文摘An asymptotic semi-analytical method for heat transfer in counter-flow honeycomb regenerator is proposed. By introducing a combined heat-transfer coefficient between the gas and solid phase, a heat transfer model is built based on the thin-walled assumption. The dimensionless thermal equation is deduced by considering solid heat conduction along the passage length. The asymptotic analysis is used for the small parameter of heat conduction term in equation. The first order asymptotic solution to temperature distribution under weak solid heat conduction is achieved after Laplace transformation through the multiple scales method and the symbolic manipulation function in MATLAB. Semi-analytical solutions agree with tests and finite-difference numerical results. It is proved possible for the asymptotic analysis to improve the effectiveness, economics and precision of thermal research on regenerator.