Restless legs syndrome (RLS) symptoms are often reported in Parkinson’s disea se (PD), but prevalence studies of RLS in PD are few and the results are inconsi stent. In addition,clinical overlapping between RLS, “we...Restless legs syndrome (RLS) symptoms are often reported in Parkinson’s disea se (PD), but prevalence studies of RLS in PD are few and the results are inconsi stent. In addition,clinical overlapping between RLS, “wearing off” related l ower limb discomfort and restlessness, and akathisia complicate the clinical ass essments of true RLS in PD. Underlying pathophysiology potentially shared by RLS and PD is mainly suggested by similarities in treatment response. Functional im aging studies in RLS are still inconclusive, although some authors have found su btle deficits in nigrostriatal terminal function. Longterm prospective studies o f RLS cohorts will clarify whether or not RLS is associated with an increased ri sk for development of PD.展开更多
周期性睡眠腿动(periodic limb movements in sleep,PLMS)是一种与睡眠相关的异常肢体活动,表现为在睡眠过程中间断出现的大脚趾有节奏地背曲,踝关节趾曲,偶有膝关节和髋关节的屈曲[1]。一般认为频繁的PLMS,如周期性睡眠腿动指数(period...周期性睡眠腿动(periodic limb movements in sleep,PLMS)是一种与睡眠相关的异常肢体活动,表现为在睡眠过程中间断出现的大脚趾有节奏地背曲,踝关节趾曲,偶有膝关节和髋关节的屈曲[1]。一般认为频繁的PLMS,如周期性睡眠腿动指数(periodic limb movement incdex,PLMI)≥15次/h可能与躯体疾病的发生和预后相关[2]。频繁发生的PLMS若合并睡眠障碍、白天嗜睡、情绪改变等症状时,考虑诊断周期性肢体活动症(periodic limb movement disorder,PLMD)。不宁腿综合征(restless legs syndrome,RLS)是另一种常见的睡眠相关肢体运动障碍,表现为休息时下肢难以抑制的不适感,运动和按摩后可暂时缓解。展开更多
腿痛趾动综合征(Painful legs and moving toes,PLMT)由Spillane等于1971年首次提出,迄今为止,国外文献报道的病例已有30例以上。该综合征的特点是脚或下肢疼痛,同时伴有足趾的不随意运动,一侧或双侧下肢受累,也可两侧下肢交替出现。本...腿痛趾动综合征(Painful legs and moving toes,PLMT)由Spillane等于1971年首次提出,迄今为止,国外文献报道的病例已有30例以上。该综合征的特点是脚或下肢疼痛,同时伴有足趾的不随意运动,一侧或双侧下肢受累,也可两侧下肢交替出现。本综合征有别于以往描述的基底节疾病以及其它肢体不随意运动疾病,已做为一个独立的疾病单元被列出。展开更多
文摘Restless legs syndrome (RLS) symptoms are often reported in Parkinson’s disea se (PD), but prevalence studies of RLS in PD are few and the results are inconsi stent. In addition,clinical overlapping between RLS, “wearing off” related l ower limb discomfort and restlessness, and akathisia complicate the clinical ass essments of true RLS in PD. Underlying pathophysiology potentially shared by RLS and PD is mainly suggested by similarities in treatment response. Functional im aging studies in RLS are still inconclusive, although some authors have found su btle deficits in nigrostriatal terminal function. Longterm prospective studies o f RLS cohorts will clarify whether or not RLS is associated with an increased ri sk for development of PD.
文摘周期性睡眠腿动(periodic limb movements in sleep,PLMS)是一种与睡眠相关的异常肢体活动,表现为在睡眠过程中间断出现的大脚趾有节奏地背曲,踝关节趾曲,偶有膝关节和髋关节的屈曲[1]。一般认为频繁的PLMS,如周期性睡眠腿动指数(periodic limb movement incdex,PLMI)≥15次/h可能与躯体疾病的发生和预后相关[2]。频繁发生的PLMS若合并睡眠障碍、白天嗜睡、情绪改变等症状时,考虑诊断周期性肢体活动症(periodic limb movement disorder,PLMD)。不宁腿综合征(restless legs syndrome,RLS)是另一种常见的睡眠相关肢体运动障碍,表现为休息时下肢难以抑制的不适感,运动和按摩后可暂时缓解。
文摘腿痛趾动综合征(Painful legs and moving toes,PLMT)由Spillane等于1971年首次提出,迄今为止,国外文献报道的病例已有30例以上。该综合征的特点是脚或下肢疼痛,同时伴有足趾的不随意运动,一侧或双侧下肢受累,也可两侧下肢交替出现。本综合征有别于以往描述的基底节疾病以及其它肢体不随意运动疾病,已做为一个独立的疾病单元被列出。
