目的分析骨质疏松性椎体压缩性骨折(OVCF)患者球囊椎体后凸成形术(BKP)后骨水泥渗漏与球囊扩张压力(BEP)的关系。方法回顾性分析在我院接受BKP的116例老年OVCF患者的临床资料,根据术前和术后72 h X射线检查和CT增强扫描结果,评估疗效和...目的分析骨质疏松性椎体压缩性骨折(OVCF)患者球囊椎体后凸成形术(BKP)后骨水泥渗漏与球囊扩张压力(BEP)的关系。方法回顾性分析在我院接受BKP的116例老年OVCF患者的临床资料,根据术前和术后72 h X射线检查和CT增强扫描结果,评估疗效和骨水泥渗漏发生情况。根据是否发生骨水泥渗漏将患者分为骨水泥渗漏组和无骨水泥渗漏组。采用视觉模拟量表(VAS)评分评估患者的疼痛程度,Barthel指数评分法评估日常生活障碍。采用受试者工作特征(ROC)曲线分析BEP和骨水泥体积预测骨水泥渗漏的曲线下面积(AUC)和最佳截断值。采用多因素Logistic回归分析影响骨水泥渗漏的危险因素。结果单节段手术82例,双节段手术27例,三节段手术7例,共涉及157节椎体。患者术后椎体前缘高度、椎体后缘高度和矢状面局部后凸Cobb角、胸腰椎后凸角均得到显著矫正,且VAS评分和Barthel指数评分均较术前改善(P<0.05)。术后24例患者发生骨水泥渗漏,其中1例发生骨水泥肺栓塞(BEP)。骨水泥渗漏组术中BEP和骨水泥体积明显大于无骨水泥渗漏组(P<0.05)。经ROC曲线分析显示,术中BEP(AUC=0.756)和骨水泥体积(AUC=0.661)都可以预测骨水泥渗漏,最佳截断值分别为135 psi和6.08 mL。多因素Logistic回归分析显示,BEP≥135 psi是骨水泥渗漏的危险因素(OR=1.038,95%CI:1.018~1.058,P<0.001)。结论BKP是治疗老年OVCF的安全有效方案,BEP较高是骨水泥渗漏的危险因素,BEP≥135 psi的患者骨水泥渗漏的风险较高。展开更多
目的:基于R语言探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的组穴规律,为针灸治疗该病提供选穴依据。方法:检索“知网”、“维普”、“万方”、“中国生物医学文献数据库”中治疗骨质疏松性压缩性骨折的相关文献,并用采用Excel...目的:基于R语言探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的组穴规律,为针灸治疗该病提供选穴依据。方法:检索“知网”、“维普”、“万方”、“中国生物医学文献数据库”中治疗骨质疏松性压缩性骨折的相关文献,并用采用Excel软件进行统计,利用R语言进行频数统计、关联规则分析、聚类分析。结果:共纳入52个处方,共包含穴位39个,选穴频数前10的穴位为:肾俞、腰阳关、命门、足三里、大肠俞、委中、阳陵泉、腰椎夹脊、三阴交、环跳;穴位归经以膀胱经为主,特定穴以背俞穴为主;关联规则分析显示以百会、脾俞、至阳、肝俞、上髎、气海、关元、大椎穴为主的核心组合;层次聚类分析得到4类、15类穴位组合。结论:探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的临床组穴规律,为临床治疗骨质疏松性椎体压缩性骨折提供选穴思路。Objective: To explore the acupuncture combination therapy regimen for osteoporotic vertebral compression fractures and provide acupoint selection guidelines based on R language. Methods: The relevant literature on the treatment of osteoporotic vertebral compression fractures was searched on “CNKI”, “VIP”, “Wanfang”, and “China Biomedical Literature Database”, and statistical analysis was conducted using Excel software. Frequency statistics, association rule analysis, and clustering analysis were conducted using R language. Results: A total of 52 prescriptions were included, containing 39 acupoints. The top 10 acupoints with the highest frequency of selection were: Shenshu, Yaoyangguan, Mingmen, Zusanli, Dachangshu, Weizhong, Yanglingquan, Yaozhuijiaji, Sanyinjiao, and Huantiao;the main meridians of the acupoints were the Bladder Meridian;the specific points were mainly back shu points;the core combination of association rule analysis was mainly Baihui, Bladder 20, Zhiyang, Shangliao, Qihai, Guanyuan, and Dazhui;the clustering analysis obtained 4 categories and 15 categories of acupoint combinations. Conclusion: This study explores the clinical acupoint combination regimen for the treatment of osteoporotic vertebral compression fractures by R language, providing acupoint selection ideas for clinical treatment of osteoporotic vertebral compression fractures.展开更多
文摘目的:基于R语言探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的组穴规律,为针灸治疗该病提供选穴依据。方法:检索“知网”、“维普”、“万方”、“中国生物医学文献数据库”中治疗骨质疏松性压缩性骨折的相关文献,并用采用Excel软件进行统计,利用R语言进行频数统计、关联规则分析、聚类分析。结果:共纳入52个处方,共包含穴位39个,选穴频数前10的穴位为:肾俞、腰阳关、命门、足三里、大肠俞、委中、阳陵泉、腰椎夹脊、三阴交、环跳;穴位归经以膀胱经为主,特定穴以背俞穴为主;关联规则分析显示以百会、脾俞、至阳、肝俞、上髎、气海、关元、大椎穴为主的核心组合;层次聚类分析得到4类、15类穴位组合。结论:探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的临床组穴规律,为临床治疗骨质疏松性椎体压缩性骨折提供选穴思路。Objective: To explore the acupuncture combination therapy regimen for osteoporotic vertebral compression fractures and provide acupoint selection guidelines based on R language. Methods: The relevant literature on the treatment of osteoporotic vertebral compression fractures was searched on “CNKI”, “VIP”, “Wanfang”, and “China Biomedical Literature Database”, and statistical analysis was conducted using Excel software. Frequency statistics, association rule analysis, and clustering analysis were conducted using R language. Results: A total of 52 prescriptions were included, containing 39 acupoints. The top 10 acupoints with the highest frequency of selection were: Shenshu, Yaoyangguan, Mingmen, Zusanli, Dachangshu, Weizhong, Yanglingquan, Yaozhuijiaji, Sanyinjiao, and Huantiao;the main meridians of the acupoints were the Bladder Meridian;the specific points were mainly back shu points;the core combination of association rule analysis was mainly Baihui, Bladder 20, Zhiyang, Shangliao, Qihai, Guanyuan, and Dazhui;the clustering analysis obtained 4 categories and 15 categories of acupoint combinations. Conclusion: This study explores the clinical acupoint combination regimen for the treatment of osteoporotic vertebral compression fractures by R language, providing acupoint selection ideas for clinical treatment of osteoporotic vertebral compression fractures.
