PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indica...PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.展开更多
患者男性,6岁。因双眼夜间视物模糊2年来我院就诊。查体：视力双眼1.0,眼压：右眼15 mm Hg（1 mm Hg=0.133 k Pa）,左眼16 mm Hg,双眼结膜无充血,角膜透明,前房深度可,瞳孔圆,直径约3 mm,对光反射可,晶状体透明,眼底：视盘边界清,C/D〈0...患者男性,6岁。因双眼夜间视物模糊2年来我院就诊。查体：视力双眼1.0,眼压：右眼15 mm Hg（1 mm Hg=0.133 k Pa）,左眼16 mm Hg,双眼结膜无充血,角膜透明,前房深度可,瞳孔圆,直径约3 mm,对光反射可,晶状体透明,眼底：视盘边界清,C/D〈0.3,动静脉颜色均呈暗红色,不易区分,部分动脉周边区血管一侧有白线,一侧有暗影,后极部视网膜平伏,后极部眼底呈锡箔样灰白色调,周边视网膜可见灰黑色大小不等密集斑块,黄斑中心凹反光存（图1）。未行眼底血管荧光造影检查,患者不能配合视野、ERG检查。展开更多
文摘PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.
文摘患者男性,6岁。因双眼夜间视物模糊2年来我院就诊。查体：视力双眼1.0,眼压：右眼15 mm Hg（1 mm Hg=0.133 k Pa）,左眼16 mm Hg,双眼结膜无充血,角膜透明,前房深度可,瞳孔圆,直径约3 mm,对光反射可,晶状体透明,眼底：视盘边界清,C/D〈0.3,动静脉颜色均呈暗红色,不易区分,部分动脉周边区血管一侧有白线,一侧有暗影,后极部视网膜平伏,后极部眼底呈锡箔样灰白色调,周边视网膜可见灰黑色大小不等密集斑块,黄斑中心凹反光存（图1）。未行眼底血管荧光造影检查,患者不能配合视野、ERG检查。
