The inclusion interactions between flavonoids and β cyclodextrin( β CD) and its derivatives have been studied by a phase solubility method. The phase solubility graphs showed that the 1∶1 inclusion compounds were f...The inclusion interactions between flavonoids and β cyclodextrin( β CD) and its derivatives have been studied by a phase solubility method. The phase solubility graphs showed that the 1∶1 inclusion compounds were formed beween β CD and rutin, qucertin and morin respectively. The compounds appeared to be a type of A L inclusion. β CD derivatives have stronger binding capacity than β CD. The enhanced solubility of compounds decreased in the order methyl β CD>hydroxypropyl β CD> β CD. The highest solubility was obtained in methyl β CD inclusion complex with qucertin in level of 50 times than that in water.展开更多
文摘The inclusion interactions between flavonoids and β cyclodextrin( β CD) and its derivatives have been studied by a phase solubility method. The phase solubility graphs showed that the 1∶1 inclusion compounds were formed beween β CD and rutin, qucertin and morin respectively. The compounds appeared to be a type of A L inclusion. β CD derivatives have stronger binding capacity than β CD. The enhanced solubility of compounds decreased in the order methyl β CD>hydroxypropyl β CD> β CD. The highest solubility was obtained in methyl β CD inclusion complex with qucertin in level of 50 times than that in water.
