计算机爱好者通常应用PCTOOLS、DISKCOPY、DUP等工具软件复制磁盘。但它们有许多不足之处。而美国Micro System Design公司推出的DISKDUPE(简称DDUP)磁盘复制工具软件克服了上述缺点,不仅速度快,质量好,而且辅助功能齐全,是一个较好的...计算机爱好者通常应用PCTOOLS、DISKCOPY、DUP等工具软件复制磁盘。但它们有许多不足之处。而美国Micro System Design公司推出的DISKDUPE(简称DDUP)磁盘复制工具软件克服了上述缺点,不仅速度快,质量好,而且辅助功能齐全,是一个较好的复制工具。展开更多
分析了数据复制技术在实时灾备系统中的应用,指出了SQL Server 2000提供的数据复制功能存在的两个问题:其一是分发代理调用系统自动生成的Update存储过程会出现错误,其二是复制数据在网络传输过程中没有采用数据压缩机制。为解决这些问...分析了数据复制技术在实时灾备系统中的应用,指出了SQL Server 2000提供的数据复制功能存在的两个问题:其一是分发代理调用系统自动生成的Update存储过程会出现错误,其二是复制数据在网络传输过程中没有采用数据压缩机制。为解决这些问题,文中通过SQL 2000的编程接口SQL-DMO和ActiveX控件开发出新的数据复制管理工具用以构建正确的基于数据复制技术的灾备环境,并采用了数据通讯压缩技术。经过对比实验,给出了数据复制系统的最优部署架构,成功地实现了基于数据复制技术的数据库灾备系统的应用。展开更多
RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the specific degradation of mRNA with identical sequences. The human herpes simplex virus type 1 (HSV-1) RR is composed ...RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the specific degradation of mRNA with identical sequences. The human herpes simplex virus type 1 (HSV-1) RR is composed of two distinct homodimeric subunits encoded by UL39 and UL40,respectively. In this study,we applied siRNAs targeting the UL39 and UL40 genes of HSV-1. We showed that synthetic siRNA silenced effectively and specifically UL39 and UL40 mRNA expression and inhibited HSV-1 replication. Our work offers new possibilities for RNAi as a genetic tool for inhibition of HSV-1 replication.展开更多
Clinical disorders often are characterized by a breakdown in dynamical processes that contribute to the control of upright standing.Disruption to a large number of physiological processes operating at different time s...Clinical disorders often are characterized by a breakdown in dynamical processes that contribute to the control of upright standing.Disruption to a large number of physiological processes operating at different time scales can lead to alterations in postural center of pressure(Co P)fluctuations.Multiscale entropy(MSE) has been used to identify differences in fluctuations of postural Co P time series between groups with and without known physiological impairments at multiple time scales.The purpose of this paper is to:1) review basic elements and current developments in entropy techniques used to assess physiological complexity;and 2) identify how MSE can provide insights into the complexity of physiological systems operating at multiple time scales that underlie the control of posture.We review and synthesize evidence from the literature providing support for MSE as a valuable tool to evaluate the breakdown in the physiological processes that accompany changes due to aging and disease in postural control.This evidence emerges from observed lower MSE values in individuals with multiple sclerosis,idiopathic scoliosis,and in older individuals with sensory impairments.Finally,we suggest some future applications of MSE that will allow for further insight into how physiological deficits impact the complexity of postural fluctuations;this information may improve the development and evaluation of new therapeutic interventions.展开更多
文摘分析了数据复制技术在实时灾备系统中的应用,指出了SQL Server 2000提供的数据复制功能存在的两个问题:其一是分发代理调用系统自动生成的Update存储过程会出现错误,其二是复制数据在网络传输过程中没有采用数据压缩机制。为解决这些问题,文中通过SQL 2000的编程接口SQL-DMO和ActiveX控件开发出新的数据复制管理工具用以构建正确的基于数据复制技术的灾备环境,并采用了数据通讯压缩技术。经过对比实验,给出了数据复制系统的最优部署架构,成功地实现了基于数据复制技术的数据库灾备系统的应用。
基金The Nation "863" Program of China(2006AA02A226)The Joint Funds of National Science Foundation of China (U0632010)+2 种基金The State KeyLaboratory of Phytochemistry and Plant Resources in West ChinaChinese Academy of Sciences (O807B11211, O807E21211)"211 grant of MOE"
文摘RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the specific degradation of mRNA with identical sequences. The human herpes simplex virus type 1 (HSV-1) RR is composed of two distinct homodimeric subunits encoded by UL39 and UL40,respectively. In this study,we applied siRNAs targeting the UL39 and UL40 genes of HSV-1. We showed that synthetic siRNA silenced effectively and specifically UL39 and UL40 mRNA expression and inhibited HSV-1 replication. Our work offers new possibilities for RNAi as a genetic tool for inhibition of HSV-1 replication.
文摘Clinical disorders often are characterized by a breakdown in dynamical processes that contribute to the control of upright standing.Disruption to a large number of physiological processes operating at different time scales can lead to alterations in postural center of pressure(Co P)fluctuations.Multiscale entropy(MSE) has been used to identify differences in fluctuations of postural Co P time series between groups with and without known physiological impairments at multiple time scales.The purpose of this paper is to:1) review basic elements and current developments in entropy techniques used to assess physiological complexity;and 2) identify how MSE can provide insights into the complexity of physiological systems operating at multiple time scales that underlie the control of posture.We review and synthesize evidence from the literature providing support for MSE as a valuable tool to evaluate the breakdown in the physiological processes that accompany changes due to aging and disease in postural control.This evidence emerges from observed lower MSE values in individuals with multiple sclerosis,idiopathic scoliosis,and in older individuals with sensory impairments.Finally,we suggest some future applications of MSE that will allow for further insight into how physiological deficits impact the complexity of postural fluctuations;this information may improve the development and evaluation of new therapeutic interventions.