Computational analysis is essential for transforming the masses of microarray datainto a mechanistic understanding of cancer. Here we present a method for findinggene functional modules of cancer from microarray data ...Computational analysis is essential for transforming the masses of microarray datainto a mechanistic understanding of cancer. Here we present a method for findinggene functional modules of cancer from microarray data and have applied it tocolon cancer. First, a colon cancer gene network and a normal colon tissue genenetwork were constructed using correlations between the genes. Then the modulesthat tended to have a homogeneous functional composition were identified by split-ting up the network. Analysis of both networks revealed that they are scale-free.Comparison of the gene functional modules for colon cancer and normal tissuesshowed that the modules’ functions changed with their structures.展开更多
The 53.667 MHz continuous-wave heavy ion RFQ has been designed and manufactured for the SSC-LINAC project.This four-rod RFQ accelerates ions with maximum mass to charge ratio of 7 from 3.728 keV/u to 143 keV/u.Measure...The 53.667 MHz continuous-wave heavy ion RFQ has been designed and manufactured for the SSC-LINAC project.This four-rod RFQ accelerates ions with maximum mass to charge ratio of 7 from 3.728 keV/u to 143 keV/u.Measurements have been carried out to check the RF performance of the cavity and the quality of the electric field.The S11 of the power coupler is adjusted to better than-44 dB,and the Q0 of the cavity is 6440.The quality of the electric field is evaluated by the perturbation method.The measurement procedure and data analysis will be discussed in detail.The error due to gravity of the perturbation bead has been corrected by averaging the fields in different quadrants.As a result,the unflatness of the electric field is±2.5%,and the dipole field component distributes from 0%to 20%in different longitudinal positions,which indicates the asymmetry of the quadrupole field.The unflatness of the quadrupole field distribution represents a good agreement with the simulation results.High power RF test and beam commissioning of the RFQ are on schedule in early 2014.展开更多
基金the National Natural Science Foundation of China （Grant No. 60234020）.
文摘Computational analysis is essential for transforming the masses of microarray datainto a mechanistic understanding of cancer. Here we present a method for findinggene functional modules of cancer from microarray data and have applied it tocolon cancer. First, a colon cancer gene network and a normal colon tissue genenetwork were constructed using correlations between the genes. Then the modulesthat tended to have a homogeneous functional composition were identified by split-ting up the network. Analysis of both networks revealed that they are scale-free.Comparison of the gene functional modules for colon cancer and normal tissuesshowed that the modules’ functions changed with their structures.
基金supported by the National Natural Science Foundation of China(Grant Nos.11079001 and 10905003)the Linear Accelerator Center of PKU-IMPCAS
文摘The 53.667 MHz continuous-wave heavy ion RFQ has been designed and manufactured for the SSC-LINAC project.This four-rod RFQ accelerates ions with maximum mass to charge ratio of 7 from 3.728 keV/u to 143 keV/u.Measurements have been carried out to check the RF performance of the cavity and the quality of the electric field.The S11 of the power coupler is adjusted to better than-44 dB,and the Q0 of the cavity is 6440.The quality of the electric field is evaluated by the perturbation method.The measurement procedure and data analysis will be discussed in detail.The error due to gravity of the perturbation bead has been corrected by averaging the fields in different quadrants.As a result,the unflatness of the electric field is±2.5%,and the dipole field component distributes from 0%to 20%in different longitudinal positions,which indicates the asymmetry of the quadrupole field.The unflatness of the quadrupole field distribution represents a good agreement with the simulation results.High power RF test and beam commissioning of the RFQ are on schedule in early 2014.
