Five new 6-O-prolinated monoacetylbritannilactones have been synthesized from N-acetylprolyl chlorides with 4-N,N-dimethylaminopyridine as catalyst and characterized by elemental analysis, IR, 1H NMR, 1H-1H COSY and M...Five new 6-O-prolinated monoacetylbritannilactones have been synthesized from N-acetylprolyl chlorides with 4-N,N-dimethylaminopyridine as catalyst and characterized by elemental analysis, IR, 1H NMR, 1H-1H COSY and MS. The compound 3b displayed a good biological activity for human HL-60 cell in vitro（ED50=4.6 mg/L）.展开更多
文摘Five new 6-O-prolinated monoacetylbritannilactones have been synthesized from N-acetylprolyl chlorides with 4-N,N-dimethylaminopyridine as catalyst and characterized by elemental analysis, IR, 1H NMR, 1H-1H COSY and MS. The compound 3b displayed a good biological activity for human HL-60 cell in vitro（ED50=4.6 mg/L）.
