The serum samples and corresponding cervical swabs were collected from 50 women with genital warts from Tianjin city, China. The neutralizing antibodies against HPV-16, -18, -58, -45, -6 and -11 in serum samples were ...The serum samples and corresponding cervical swabs were collected from 50 women with genital warts from Tianjin city, China. The neutralizing antibodies against HPV-16, -18, -58, -45, -6 and -11 in serum samples were tested by using pseudovirus-based neutralization assays and HPV DNAs in cervical swabs were also tested by using a typing kit that can detect 21 types of HPV. The results revealed that 36% （18/50） of sera were positive for type-specific neutralizing antibodies with a titer range of 160-2560, of which 22%（11/50）, 12%（6/50）, 10%（5/50）, 4%（2/50）, 4%（2/50） and 2%（1/50） were against HPVs -6, -16, -18, -58, -45 and -1 l, respectively. Additionally, 60% （30/50） of samples were HPV DNA-positive, in which the most common types detected were HPV-68（18%）, HPV-16（14%）, HPV-58（12%）, HPV-33（8%） and HPV-6, HPV-11, HPV-18 and HPV-52 （6% each）. The concordance between HPV DNA and corresponding neutralizing antibodies was 56% （28/50） with a significant difference （P〈0.05）. The full-length sequences of five HPV types （HPV -42, -52, -53, -58 and -68） were determined and exhibited 98%-100% identities with their reported genomes. The present data may have utility for investigating the natural history of HPV infection and promote the development of HPV vaccines.展开更多
The North China Plain(NCP) has recently faced serious air quality problems as a result of enhanced gas pollutant emissions due to the process of urbanization and rapid economic growth.To explore regional air pollution...The North China Plain(NCP) has recently faced serious air quality problems as a result of enhanced gas pollutant emissions due to the process of urbanization and rapid economic growth.To explore regional air pollution in the NCP,measurements of surface ozone(O3),nitrogen oxides(NOx),and sulfur dioxide(SO2) were carried out from May to November 2013 at a rural site(Xianghe) between the twin megacities of Beijing and Tianjin.The highest hourly ozone average was close to 240 ppbv in May,followed by around 160 ppbv in June and July.High ozone episodes were more notable than in 2005 and were mainly associated with air parcels from the city cluster in the hinterland of the polluted NCP to the southwest of the site.For NOx,an important ozone precursor,the concentrations ranged from several ppbv to nearly 180 ppbv in the summer and over 400 ppbv in the fall.The occurrence of high NOx concentrations under calm conditions indicated that local emissions were dominant in Xianghe.The double-peak diurnal pattern found in NOxconcentrations and NO/NOx ratios was probably shaped by local emissions,photochemical removal,and dilution resulting from diurnal variations of surface wind speed and the boundary layer height.A pronounced SO2 daytime peak was noted and attributed to downward mixing from an SO2-rich layer above,while the SO2-polluted air mass transported from possible emission sources,which differed between the non-heating(September and October) and heating(November) periods,was thought to be responsible for night-time high concentrations.展开更多
Based on introducing geological structure of Tanggu area, the authors analyzed the sedimentary environment of Paleogene Dongying Formation, and further analyzed its geothermal occurrence. The studied area spans two gr...Based on introducing geological structure of Tanggu area, the authors analyzed the sedimentary environment of Paleogene Dongying Formation, and further analyzed its geothermal occurrence. The studied area spans two grade IV tectonic units which are Beitang depression and Banqiao depression. The studied area is mainly located in the Tanggu nose-like structure which is the secondary structure of Beitang depression. Its existence affects the sedimentary distribution of the part strata of Paleogene. The depositions of Dongying Ⅲ （ SQEd3 ） and Dongying Ⅱ （ SQEd2 ） are mainly delta front facies and lake sand bars which are propitious to the geothermal fluid enrichment. The favorable enrichment region of geothermal fluid is located in south Hetou- Tanggu. Most of Dongying Ⅰ （ SQEd1 ） changes into swamp plain deposition, only the northeast part of this area is the distributary riverway facies with developed sand layers. There is the favorable enrichment region of geothermal fluid. The hydraulic connection is weak among the geothermal reservoirs of Dongying Formation and its overlying Guantao and Minghuazhen formations. The underlying Shahejie Formation geothermal reservoir pro- vides a steady stream of fluid supply and ground pressure protection for Dongying Formation geothermal reservoir.展开更多
An effective evaluation system can provide specific and practical suggestions to the deep groundwater management. But such kind of evaluation system has not been proposed in China. In this study, an evaluation index s...An effective evaluation system can provide specific and practical suggestions to the deep groundwater management. But such kind of evaluation system has not been proposed in China. In this study, an evaluation index system is specifically developed to evaluate deep groundwater management efficiency. It is composed of three first-level indicators(law enforcement capability, management ability, and management effectiveness) and eleven second-level indicators. The second-level indicators include seven mandatory indicators and four optional indicators. Piecewise linear function is used to normalize the quantitative indicators, and expert scoring method and questionnaire survey method are used to normalize the qualitative indicators. Then a comprehensive indicator weighting evaluation method is used to evaluate the first-level indicators and the target topic. A case study is carried out to evaluate deep groundwater management efficiency in Tianjin City. According to the evaluation score in each period, the management efficiency of every district in Tianjin City gradually improved. The overall evaluation score in the early deep groundwater extraction period is 0.12. After a series of deep groundwater protection efforts, this score reached to 0.61 in 2007, and met the regulation criteria. The evaluation results also showed that the further groundwater management efforts in Tianjin City should be focused on building a dynamic database to collect comprehensive deep well-log data; and on a reasonable design and distribution of the groundwater monitoring network. It demonstrated that the index system is suitable to locate the deficiencies of current groundwater management systems and to guide further improvements. It can then be used to protect deep groundwater.展开更多
As the development of productive forces, the most critical and most active factors in people is the fimdamental driving force of regional economic sustainable development and cooperation has a vital role in regional e...As the development of productive forces, the most critical and most active factors in people is the fimdamental driving force of regional economic sustainable development and cooperation has a vital role in regional economic development Only speed up regional economic cooperation and enforce the integration of regional talent development, can the Beijing-Tianjin-Hebei region achieves rapid development, and become China＇ s third largest economic growth pole, following the Pearl River Delta and Yangtze River Delta. Based on reviewing the integration process of the integration of regional talent development in the Beijing-Tianjin-Hebci region, this paper further analyze differences in the economic development status, the level of human capital, wage levels, employment status, and the development of educational science and technology among Hebei Province, Beijing and Tianjin, and concludes talent development strategy for Hebei Province replying the personnel integration of Beijing, Tianjin and Hebei Province.展开更多
文摘The serum samples and corresponding cervical swabs were collected from 50 women with genital warts from Tianjin city, China. The neutralizing antibodies against HPV-16, -18, -58, -45, -6 and -11 in serum samples were tested by using pseudovirus-based neutralization assays and HPV DNAs in cervical swabs were also tested by using a typing kit that can detect 21 types of HPV. The results revealed that 36% （18/50） of sera were positive for type-specific neutralizing antibodies with a titer range of 160-2560, of which 22%（11/50）, 12%（6/50）, 10%（5/50）, 4%（2/50）, 4%（2/50） and 2%（1/50） were against HPVs -6, -16, -18, -58, -45 and -1 l, respectively. Additionally, 60% （30/50） of samples were HPV DNA-positive, in which the most common types detected were HPV-68（18%）, HPV-16（14%）, HPV-58（12%）, HPV-33（8%） and HPV-6, HPV-11, HPV-18 and HPV-52 （6% each）. The concordance between HPV DNA and corresponding neutralizing antibodies was 56% （28/50） with a significant difference （P〈0.05）. The full-length sequences of five HPV types （HPV -42, -52, -53, -58 and -68） were determined and exhibited 98%-100% identities with their reported genomes. The present data may have utility for investigating the natural history of HPV infection and promote the development of HPV vaccines.
基金supported by the National Natural Science Foundation of China (Grant Nos.41305114 and 41175030)supported by Beijing Municipal Natural Science Foundation (Grant No.8121002)
文摘The North China Plain(NCP) has recently faced serious air quality problems as a result of enhanced gas pollutant emissions due to the process of urbanization and rapid economic growth.To explore regional air pollution in the NCP,measurements of surface ozone(O3),nitrogen oxides(NOx),and sulfur dioxide(SO2) were carried out from May to November 2013 at a rural site(Xianghe) between the twin megacities of Beijing and Tianjin.The highest hourly ozone average was close to 240 ppbv in May,followed by around 160 ppbv in June and July.High ozone episodes were more notable than in 2005 and were mainly associated with air parcels from the city cluster in the hinterland of the polluted NCP to the southwest of the site.For NOx,an important ozone precursor,the concentrations ranged from several ppbv to nearly 180 ppbv in the summer and over 400 ppbv in the fall.The occurrence of high NOx concentrations under calm conditions indicated that local emissions were dominant in Xianghe.The double-peak diurnal pattern found in NOxconcentrations and NO/NOx ratios was probably shaped by local emissions,photochemical removal,and dilution resulting from diurnal variations of surface wind speed and the boundary layer height.A pronounced SO2 daytime peak was noted and attributed to downward mixing from an SO2-rich layer above,while the SO2-polluted air mass transported from possible emission sources,which differed between the non-heating(September and October) and heating(November) periods,was thought to be responsible for night-time high concentrations.
基金Supported by Project of Dongying Geothermal Resources Survey in Tanggu area of Tianjin(Tianjin Land and Housing Task[2008]No.003)
文摘Based on introducing geological structure of Tanggu area, the authors analyzed the sedimentary environment of Paleogene Dongying Formation, and further analyzed its geothermal occurrence. The studied area spans two grade IV tectonic units which are Beitang depression and Banqiao depression. The studied area is mainly located in the Tanggu nose-like structure which is the secondary structure of Beitang depression. Its existence affects the sedimentary distribution of the part strata of Paleogene. The depositions of Dongying Ⅲ （ SQEd3 ） and Dongying Ⅱ （ SQEd2 ） are mainly delta front facies and lake sand bars which are propitious to the geothermal fluid enrichment. The favorable enrichment region of geothermal fluid is located in south Hetou- Tanggu. Most of Dongying Ⅰ （ SQEd1 ） changes into swamp plain deposition, only the northeast part of this area is the distributary riverway facies with developed sand layers. There is the favorable enrichment region of geothermal fluid. The hydraulic connection is weak among the geothermal reservoirs of Dongying Formation and its overlying Guantao and Minghuazhen formations. The underlying Shahejie Formation geothermal reservoir pro- vides a steady stream of fluid supply and ground pressure protection for Dongying Formation geothermal reservoir.
基金Under the auspices of National Basic Research Program of China(No.2010CB428804)
文摘An effective evaluation system can provide specific and practical suggestions to the deep groundwater management. But such kind of evaluation system has not been proposed in China. In this study, an evaluation index system is specifically developed to evaluate deep groundwater management efficiency. It is composed of three first-level indicators(law enforcement capability, management ability, and management effectiveness) and eleven second-level indicators. The second-level indicators include seven mandatory indicators and four optional indicators. Piecewise linear function is used to normalize the quantitative indicators, and expert scoring method and questionnaire survey method are used to normalize the qualitative indicators. Then a comprehensive indicator weighting evaluation method is used to evaluate the first-level indicators and the target topic. A case study is carried out to evaluate deep groundwater management efficiency in Tianjin City. According to the evaluation score in each period, the management efficiency of every district in Tianjin City gradually improved. The overall evaluation score in the early deep groundwater extraction period is 0.12. After a series of deep groundwater protection efforts, this score reached to 0.61 in 2007, and met the regulation criteria. The evaluation results also showed that the further groundwater management efforts in Tianjin City should be focused on building a dynamic database to collect comprehensive deep well-log data; and on a reasonable design and distribution of the groundwater monitoring network. It demonstrated that the index system is suitable to locate the deficiencies of current groundwater management systems and to guide further improvements. It can then be used to protect deep groundwater.
文摘As the development of productive forces, the most critical and most active factors in people is the fimdamental driving force of regional economic sustainable development and cooperation has a vital role in regional economic development Only speed up regional economic cooperation and enforce the integration of regional talent development, can the Beijing-Tianjin-Hebei region achieves rapid development, and become China＇ s third largest economic growth pole, following the Pearl River Delta and Yangtze River Delta. Based on reviewing the integration process of the integration of regional talent development in the Beijing-Tianjin-Hebci region, this paper further analyze differences in the economic development status, the level of human capital, wage levels, employment status, and the development of educational science and technology among Hebei Province, Beijing and Tianjin, and concludes talent development strategy for Hebei Province replying the personnel integration of Beijing, Tianjin and Hebei Province.
